BRPI0517643A - derivados de ácido piridono-carboxìlico ou seus sais - Google Patents
derivados de ácido piridono-carboxìlico ou seus saisInfo
- Publication number
- BRPI0517643A BRPI0517643A BRPI0517643-3A BRPI0517643A BRPI0517643A BR PI0517643 A BRPI0517643 A BR PI0517643A BR PI0517643 A BRPI0517643 A BR PI0517643A BR PI0517643 A BRPI0517643 A BR PI0517643A
- Authority
- BR
- Brazil
- Prior art keywords
- atom
- present
- pyridono
- salts
- group
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- YSLIPUSJNFIFAB-UHFFFAOYSA-N 2-oxopyridine-1-carboxylic acid Chemical class OC(=O)N1C=CC=CC1=O YSLIPUSJNFIFAB-UHFFFAOYSA-N 0.000 abstract 1
- 102000004506 Blood Proteins Human genes 0.000 abstract 1
- 108010017384 Blood Proteins Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
DERIVADOS DE ACIDO PIRIDONO-CARBOXILICO OU SEUS SAIS. A invenção propõe medicamentos que apresentam uma atividade antibacteriana excelente, baixa toxicidade, uma melhor biodisponibilidade e baixos graus de ligação àsproteínas do plasma. Os derivados de ácidos piridono-carbo-xílicos representados pela fórmula geral (1) ou seus sais; e agentes antibacterianos ou medicamentos, contendo os mesmos. A fórmula geral (1) em que R e metila, flúor ou cloro; R e hidrogênio ou alquila inferior; R é isopropila ou tercbutila; R~ 4~ é metila ou halogênio; e R~ 5~ é flúor ou cloro.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004333244 | 2004-11-17 | ||
| PCT/JP2005/021093 WO2006054623A1 (ja) | 2004-11-17 | 2005-11-17 | 新規ピリドンカルボン酸誘導体又はその塩 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0517643A true BRPI0517643A (pt) | 2008-10-14 |
Family
ID=36407161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0517643-3A BRPI0517643A (pt) | 2004-11-17 | 2005-11-17 | derivados de ácido piridono-carboxìlico ou seus sais |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7713997B2 (pt) |
| EP (1) | EP1813610B1 (pt) |
| JP (1) | JP3995705B2 (pt) |
| KR (1) | KR20070084159A (pt) |
| CN (1) | CN101061109B (pt) |
| AT (1) | ATE480535T1 (pt) |
| AU (1) | AU2005307447B2 (pt) |
| BR (1) | BRPI0517643A (pt) |
| CA (1) | CA2588034A1 (pt) |
| CY (1) | CY1110898T1 (pt) |
| DE (1) | DE602005023513D1 (pt) |
| DK (1) | DK1813610T3 (pt) |
| ES (1) | ES2349278T3 (pt) |
| MX (1) | MX2007005892A (pt) |
| PL (1) | PL1813610T3 (pt) |
| PT (1) | PT1813610E (pt) |
| RU (1) | RU2379304C2 (pt) |
| SI (1) | SI1813610T1 (pt) |
| WO (1) | WO2006054623A1 (pt) |
| ZA (1) | ZA200704862B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112018076175A2 (pt) * | 2016-06-15 | 2019-03-26 | Wakunaga Pharmaceutical Co., Ltd. | novo derivado de ácido piridonacarboxílico ou sal deste |
| RU2634122C1 (ru) * | 2016-12-14 | 2017-10-24 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Фторхинолоны на основе 4-дезоксипиридоксина |
| CN114539213A (zh) * | 2021-08-18 | 2022-05-27 | 广东工业大学 | 一种氟喹诺酮类化合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69231422T2 (de) * | 1991-05-28 | 2001-03-29 | Daiichi Pharmaceutical Co., Ltd. | Pyridoncarbonsäurederivate |
| DK0992501T3 (da) * | 1995-09-22 | 2002-10-28 | Wakunaga Pharma Co Ltd | Pyridoncarboxylsyre derivater som antibakterielle midler |
| MXPA02000103A (es) * | 1999-07-01 | 2003-07-21 | Wakunaga Pharma Co Ltd | Derivado de acido quinolin carboxilico o sales del mismo. |
| JP2004521892A (ja) * | 2000-12-20 | 2004-07-22 | メルク エンド カムパニー インコーポレーテッド | （ハロ−ベンゾカルボニル）複素環縮合フェニル系ｐ３８キナーゼ阻害剤 |
-
2005
- 2005-11-17 JP JP2006545116A patent/JP3995705B2/ja not_active Expired - Fee Related
- 2005-11-17 CA CA002588034A patent/CA2588034A1/en not_active Abandoned
- 2005-11-17 RU RU2007122499/04A patent/RU2379304C2/ru not_active IP Right Cessation
- 2005-11-17 AT AT05806666T patent/ATE480535T1/de active
- 2005-11-17 ZA ZA200704862A patent/ZA200704862B/xx unknown
- 2005-11-17 DE DE602005023513T patent/DE602005023513D1/de not_active Expired - Lifetime
- 2005-11-17 ES ES05806666T patent/ES2349278T3/es not_active Expired - Lifetime
- 2005-11-17 EP EP05806666A patent/EP1813610B1/en not_active Expired - Lifetime
- 2005-11-17 DK DK05806666.3T patent/DK1813610T3/da active
- 2005-11-17 CN CN2005800394017A patent/CN101061109B/zh not_active Expired - Fee Related
- 2005-11-17 SI SI200531160T patent/SI1813610T1/sl unknown
- 2005-11-17 WO PCT/JP2005/021093 patent/WO2006054623A1/ja not_active Ceased
- 2005-11-17 PT PT05806666T patent/PT1813610E/pt unknown
- 2005-11-17 PL PL05806666T patent/PL1813610T3/pl unknown
- 2005-11-17 US US11/719,547 patent/US7713997B2/en not_active Expired - Fee Related
- 2005-11-17 KR KR1020077010652A patent/KR20070084159A/ko not_active Ceased
- 2005-11-17 AU AU2005307447A patent/AU2005307447B2/en not_active Ceased
- 2005-11-17 MX MX2007005892A patent/MX2007005892A/es active IP Right Grant
- 2005-11-17 BR BRPI0517643-3A patent/BRPI0517643A/pt not_active IP Right Cessation
-
2010
- 2010-11-12 CY CY20101101020T patent/CY1110898T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE480535T1 (de) | 2010-09-15 |
| AU2005307447A1 (en) | 2006-05-26 |
| AU2005307447B2 (en) | 2011-03-10 |
| KR20070084159A (ko) | 2007-08-24 |
| EP1813610A4 (en) | 2009-05-20 |
| ES2349278T3 (es) | 2010-12-29 |
| JP3995705B2 (ja) | 2007-10-24 |
| PT1813610E (pt) | 2010-10-11 |
| CN101061109A (zh) | 2007-10-24 |
| CY1110898T1 (el) | 2015-06-10 |
| RU2379304C2 (ru) | 2010-01-20 |
| US20090149440A1 (en) | 2009-06-11 |
| SI1813610T1 (sl) | 2010-12-31 |
| HK1109616A1 (en) | 2008-06-13 |
| US7713997B2 (en) | 2010-05-11 |
| DK1813610T3 (da) | 2010-12-06 |
| PL1813610T3 (pl) | 2011-02-28 |
| WO2006054623A1 (ja) | 2006-05-26 |
| EP1813610A1 (en) | 2007-08-01 |
| RU2007122499A (ru) | 2008-12-27 |
| CN101061109B (zh) | 2011-05-25 |
| CA2588034A1 (en) | 2006-05-26 |
| ZA200704862B (en) | 2008-12-31 |
| JPWO2006054623A1 (ja) | 2008-05-29 |
| MX2007005892A (es) | 2007-06-19 |
| EP1813610B1 (en) | 2010-09-08 |
| DE602005023513D1 (de) | 2010-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |