BRPI0518101A - métodos de produção e sìntese de composições nanoparticuladas, composições obtidas e seu uso - Google Patents

métodos de produção e sìntese de composições nanoparticuladas, composições obtidas e seu uso

Info

Publication number
BRPI0518101A
BRPI0518101A BRPI0518101-1A BRPI0518101A BRPI0518101A BR PI0518101 A BRPI0518101 A BR PI0518101A BR PI0518101 A BRPI0518101 A BR PI0518101A BR PI0518101 A BRPI0518101 A BR PI0518101A
Authority
BR
Brazil
Prior art keywords
compositions
nanoparticulate
present
synthesis
nanoparticulate compositions
Prior art date
Application number
BRPI0518101-1A
Other languages
English (en)
Inventor
Trevor Payne
Felix Meiser
Almar Postma
Raffaele Cammarano
Frank Caruso
James Williams
Paul Mccormick
Aaron Dodd
Original Assignee
Iceutica Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004907377A external-priority patent/AU2004907377A0/en
Application filed by Iceutica Pty Ltd filed Critical Iceutica Pty Ltd
Publication of BRPI0518101A publication Critical patent/BRPI0518101A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MéTODOS DE PRODUçãO E SìNTESE DE COMPOSIçõES NANOPARTICULADAS. Trata-se a presente invenção de composições m icroestruturais melhoradas de nanocompósitos terapeuticamente ativos, que incluem composições nanoparticuladas e preparações nanoparticuladas. As modalidades preferidas da presente invenção incluem composições nanoparticuladas, que compreendem nanopartículas de um agente terapeuticamente ativo dispersas em uma matriz carreadora. A presente invenção também se refere a um método para o preparo das ditas composições nanoparticuladas e preparações nanoparticuladas, por meio do uso da sintese mecanoquímica no estado sólido. Adicionalmente, a presente invenção também se refere aos produtos terapêuticos produzidos por meio do uso das ditas composições nanoparticuladas, bem como a métodos de tratamento, por meio do uso das ditas composições nanoparticuladas.
BRPI0518101-1A 2004-12-31 2005-12-30 métodos de produção e sìntese de composições nanoparticuladas, composições obtidas e seu uso BRPI0518101A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2004907377A AU2004907377A0 (en) 2004-12-31 Nano-Particle Composition(s) and Method for Synthesis Thereof
PCT/AU2005/001977 WO2006069419A1 (en) 2004-12-31 2005-12-30 Nanoparticle composition and methods for synthesis thereof

Publications (1)

Publication Number Publication Date
BRPI0518101A true BRPI0518101A (pt) 2008-10-28

Family

ID=36614419

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518101-1A BRPI0518101A (pt) 2004-12-31 2005-12-30 métodos de produção e sìntese de composições nanoparticuladas, composições obtidas e seu uso

Country Status (10)

Country Link
US (4) US20090028948A1 (pt)
EP (1) EP1830824B1 (pt)
JP (2) JP6091041B2 (pt)
CN (2) CN101094659A (pt)
BR (1) BRPI0518101A (pt)
CA (2) CA2858733C (pt)
IL (1) IL183843A (pt)
NZ (1) NZ555719A (pt)
WO (1) WO2006069419A1 (pt)
ZA (1) ZA200704613B (pt)

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Also Published As

Publication number Publication date
IL183843A (en) 2017-01-31
CN101094659A (zh) 2007-12-26
JP2008526689A (ja) 2008-07-24
US20250387343A1 (en) 2025-12-25
EP1830824A4 (en) 2012-08-29
CA2858733C (en) 2017-12-19
JP6113878B2 (ja) 2017-04-12
EP1830824A1 (en) 2007-09-12
IL183843A0 (en) 2007-10-31
US20090028948A1 (en) 2009-01-29
NZ555719A (en) 2010-11-26
EP1830824B1 (en) 2016-01-13
JP2016106123A (ja) 2016-06-16
JP6091041B2 (ja) 2017-03-08
CN104083342A (zh) 2014-10-08
US20200360294A1 (en) 2020-11-19
US20180169028A1 (en) 2018-06-21
ZA200704613B (en) 2008-05-28
CA2593862A1 (en) 2006-07-06
CA2593862C (en) 2014-10-21
WO2006069419A1 (en) 2006-07-06
CA2858733A1 (en) 2006-07-06

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]