BRPI0518600A2 - produto mÉdico compreendendo um medicamento de peptÍdeo tipo glucagon, idealizado para inalaÇço pulmonar - Google Patents

produto mÉdico compreendendo um medicamento de peptÍdeo tipo glucagon, idealizado para inalaÇço pulmonar

Info

Publication number
BRPI0518600A2
BRPI0518600A2 BRPI0518600-5A BRPI0518600A BRPI0518600A2 BR PI0518600 A2 BRPI0518600 A2 BR PI0518600A2 BR PI0518600 A BRPI0518600 A BR PI0518600A BR PI0518600 A2 BRPI0518600 A2 BR PI0518600A2
Authority
BR
Brazil
Prior art keywords
medical product
glucagon
pulmonary inhalation
container
inhalation
Prior art date
Application number
BRPI0518600-5A
Other languages
English (en)
Inventor
Thomas Nilsson
Sven Calander
Alf Niemi
Claes Friberg
Lars Kax
Mattias Myrman
Original Assignee
Mederio Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mederio Ag filed Critical Mederio Ag
Priority claimed from PCT/SE2005/001648 external-priority patent/WO2006059939A1/en
Publication of BRPI0518600A2 publication Critical patent/BRPI0518600A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Packages (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PRODUTO MÉDICO COMPREENDENDO UM MEDICANENTO DE PEPTÍDEO TIPO GLUCAGON, IDEALIZADO PARA INALAÇçO PULMONAR. A presente invenção divulga um produto médico. Basicamente, o produto médico compreende uma dose precisamente aferida de um medicamento de peptídeo tipo glucagon (GLP), idealizada para inalação pulmonar e colocada em um recipiente com vedação de alta proteção de barreira e à prova de umidade. Opcionalmente, o produto médico também compreende uma dose de insulina. O recipiente é adaptado para aplicação em um inalador de pó seco. A dose introduzida no recipiente é idealizada para uma liberação prolongada, mediante inalação profunda ao pulmão, quando os ingredientes ativos são absorvidos dentro do sistema. Opcionalmente, o produto médico pode também compreender pelo menos um excipiente biologicamente aceitável.
BRPI0518600-5A 2004-12-03 2005-11-02 produto mÉdico compreendendo um medicamento de peptÍdeo tipo glucagon, idealizado para inalaÇço pulmonar BRPI0518600A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0402976A SE0402976L (sv) 2004-12-03 2004-12-03 Medicinsk produkt
US11/049,696 US20060120969A1 (en) 2004-12-03 2005-02-04 Medical product for inhalation containing glucagon-like peptide-1 (GLP-1)
PCT/SE2005/001648 WO2006059939A1 (en) 2004-12-03 2005-11-02 A medical product comprising a glucagon-like peptide medicament intended for pulmonary inhalation

Publications (1)

Publication Number Publication Date
BRPI0518600A2 true BRPI0518600A2 (pt) 2008-11-25

Family

ID=33550603

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518600-5A BRPI0518600A2 (pt) 2004-12-03 2005-11-02 produto mÉdico compreendendo um medicamento de peptÍdeo tipo glucagon, idealizado para inalaÇço pulmonar

Country Status (9)

Country Link
US (2) US20060120969A1 (pt)
JP (1) JP2008521893A (pt)
CN (1) CN101111226A (pt)
BR (1) BRPI0518600A2 (pt)
IL (1) IL183623A0 (pt)
MX (1) MX2007006533A (pt)
RU (1) RU2007124795A (pt)
SE (1) SE0402976L (pt)
ZA (1) ZA200705376B (pt)

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US8921311B2 (en) 2003-08-01 2014-12-30 Mannkind Corporation Method for treating hyperglycemia
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CN102131516B (zh) 2008-06-27 2016-03-16 杜克大学 包含弹性蛋白样肽的治疗剂
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
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CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
CN102596175A (zh) 2009-07-06 2012-07-18 赛诺菲-安万特德国有限公司 含有甲硫氨酸的水性胰岛素制备物
JP5801997B2 (ja) * 2009-07-07 2015-10-28 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器
US8642548B2 (en) 2009-08-07 2014-02-04 Mannkind Corporation Val (8) GLP-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
US20110118178A1 (en) * 2009-11-13 2011-05-19 Sanofi-Aventis Deutschland Gmbh Method of treatment of diabetes type 2 comprising add-on therapy to insulin glargine and metformin
PT3345593T (pt) 2009-11-13 2023-11-27 Sanofi Aventis Deutschland Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina
MY180661A (en) 2009-11-13 2020-12-04 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist, an insulin and methionine
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2011121425A1 (en) * 2010-03-31 2011-10-06 Glenmark Pharmaceuticals Limited Pharmaceutical powder composition for inhalation
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
PL2611458T3 (pl) 2010-08-30 2017-02-28 Sanofi-Aventis Deutschland Gmbh Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2
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US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
AR087693A1 (es) 2011-08-29 2014-04-09 Sanofi Aventis Deutschland Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
AU2014228415B2 (en) 2013-03-15 2018-08-09 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
US20150038674A1 (en) * 2013-08-05 2015-02-05 Bayrak Bertan Boran Use of glp-2 analogues in pulmonary diseases for therapeutic purpose
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Also Published As

Publication number Publication date
IL183623A0 (en) 2007-09-20
MX2007006533A (es) 2007-08-02
SE0402976D0 (sv) 2004-12-03
RU2007124795A (ru) 2009-01-10
CN101111226A (zh) 2008-01-23
SE0402976L (sv) 2006-06-04
ZA200705376B (en) 2008-12-31
JP2008521893A (ja) 2008-06-26
US20060120969A1 (en) 2006-06-08
US20060239933A1 (en) 2006-10-26

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Legal Events

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]