BRPI0518952A2 - mÉtodo para a produÇço de um agente de contraste marcador ou um agente terapÊutico, agentes de contraste marcadores, e, uso dos agentes de contraste marcadores ou dos agentes terapÊuticos de marcaÇço - Google Patents
mÉtodo para a produÇço de um agente de contraste marcador ou um agente terapÊutico, agentes de contraste marcadores, e, uso dos agentes de contraste marcadores ou dos agentes terapÊuticos de marcaÇçoInfo
- Publication number
- BRPI0518952A2 BRPI0518952A2 BRPI0518952-7A BRPI0518952A BRPI0518952A2 BR PI0518952 A2 BRPI0518952 A2 BR PI0518952A2 BR PI0518952 A BRPI0518952 A BR PI0518952A BR PI0518952 A2 BRPI0518952 A2 BR PI0518952A2
- Authority
- BR
- Brazil
- Prior art keywords
- agents
- marker contrast
- therapeutic
- agent
- marker
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
- A61K49/0067—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle quantum dots, fluorescent nanocrystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1255—Granulates, agglomerates, microspheres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Optics & Photonics (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mathematical Physics (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Theoretical Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
MÉTODO PARA A PRODUÇçO DE UM AGENTE DE CONTRASTE MARCADOR OU UM AGENTE TERAPÊUTICO, AGENTES DE CONTRASTE MARCADORES, E, USO DOS AGENTES DE CONTRASTE MARCADORES OU DOS AGENTES TERAPÊUTICOS DE MARCAÇçO. Esta invenção diz respeito a um método de sintetizar agentes de contraste para formação de imagem molecular e diagnóstico e terapia de marcação, agentes de contraste marcadores e agentes terapêuticos marcadores, e seu uso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04106694 | 2004-12-17 | ||
| PCT/IB2005/054185 WO2006064451A2 (en) | 2004-12-17 | 2005-12-12 | Targeting contrast agents or targeting therapeutic agents for molecular imaging and therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0518952A2 true BRPI0518952A2 (pt) | 2008-12-16 |
Family
ID=36174791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0518952-7A BRPI0518952A2 (pt) | 2004-12-17 | 2005-12-12 | mÉtodo para a produÇço de um agente de contraste marcador ou um agente terapÊutico, agentes de contraste marcadores, e, uso dos agentes de contraste marcadores ou dos agentes terapÊuticos de marcaÇço |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090238767A1 (pt) |
| EP (1) | EP1827506A2 (pt) |
| JP (1) | JP2008524202A (pt) |
| CN (1) | CN101080240A (pt) |
| BR (1) | BRPI0518952A2 (pt) |
| RU (1) | RU2007127314A (pt) |
| WO (1) | WO2006064451A2 (pt) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117883596A (zh) * | 2022-10-09 | 2024-04-16 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种乏氧响应的t1-t2可切换型mri造影剂、其制备方法及应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7635680B2 (en) | 2001-02-21 | 2009-12-22 | Alavita Pharmaceuticals, Inc. | Attenuation of reperfusion injury |
| WO2006138145A1 (en) | 2005-06-14 | 2006-12-28 | Northwestern University | Nucleic acid functionalized nanoparticles for therapeutic applications |
| EP1921081A1 (en) | 2006-11-06 | 2008-05-14 | Koninklijke Philips Electronics N.V. | Use of arylboronic acids in protein labelling |
| AU2008212820B2 (en) | 2007-02-09 | 2014-01-30 | Northwestern University | Particles for detecting intracellular targets |
| JP2008266194A (ja) * | 2007-04-19 | 2008-11-06 | Hiroshi Tanaka | 分子プローブの原料として有用な新規有機化合物 |
| GB0709561D0 (en) * | 2007-05-18 | 2007-06-27 | Siemens Medical Solutions | Assessment of vascular compartment volume PET modeling |
| EP2005973A1 (de) * | 2007-06-22 | 2008-12-24 | nanoPET Pharma GmbH | Positronen emittierende anorganische Partikel enthaltende Zusammensetzungen und deren Verwendung in der Medizin, insbesondere für diagnostische Verfahren |
| KR101031049B1 (ko) * | 2008-04-17 | 2011-04-25 | 한국생명공학연구원 | 다기능성 퍼플루오르카본 나노 에멀젼을 이용한 세포 표지및 영상화 |
| GB0811856D0 (en) | 2008-06-27 | 2008-07-30 | Ucl Business Plc | Magnetic microbubbles, methods of preparing them and their uses |
| KR101094207B1 (ko) * | 2008-08-21 | 2011-12-14 | 연세대학교 산학협력단 | T1―t2 이중방식 mri 조영제 |
| JP5427329B2 (ja) * | 2008-08-30 | 2014-02-26 | 国立大学法人九州大学 | 金微粒子とその製造方法 |
| WO2010055950A1 (ja) | 2008-11-17 | 2010-05-20 | 財団法人ヒューマンサイエンス振興財団 | 癌間質の構成因子に対して特異的結合能を有する物質と抗腫瘍性化合物との複合体による新規の癌ターゲティング治療 |
| DK2365803T3 (en) | 2008-11-24 | 2018-01-22 | Univ Northwestern | POLYVALENT RNA NANOPARTICLE COMPOSITIONS |
| BRPI0923859B8 (pt) * | 2008-12-29 | 2022-10-25 | Gen Electric | composição de agente de diagnóstico, e, método para a produção das nanopartículas |
| US9399075B2 (en) | 2008-12-29 | 2016-07-26 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| US20100233270A1 (en) | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
| JP5847588B2 (ja) * | 2009-02-13 | 2016-01-27 | ユニヴァーシティ オブ ワシントン | 磁気共鳴イメージングのためのガドリニウム発現脂質ナノ粒子 |
| BRPI0924549A2 (pt) * | 2009-06-12 | 2016-04-26 | Amrita Vishwa Vidyapeetham University | nano fotomedicamentos como alvo para terapia fotodinâmica do câncer |
| US20120277283A1 (en) * | 2009-08-04 | 2012-11-01 | Mirkin Chad A | Localized Delivery of Gold Nanoparticles for Therapeutic and Diagnostic Applications |
| US20120269730A1 (en) * | 2009-08-07 | 2012-10-25 | Northwestern University | Intracellular Delivery of Contrast Agents with Functionalized Nanoparticles |
| JP5866119B2 (ja) | 2009-10-30 | 2016-02-17 | ノースウェスタン ユニバーシティ | 鋳型ナノ複合体 |
| EP2493458A2 (en) * | 2009-10-30 | 2012-09-05 | The Ohio State University | Multi-functional biodegradable particles for selectable targeting, imaging, and therapeutic delivery and use thereof for treating ocular disorders |
| WO2011084641A2 (en) * | 2009-12-16 | 2011-07-14 | The Regents Of The University Of California | Gold coating of rare earth nano-phosphors and uses thereof |
| EP2416345A1 (en) | 2010-08-06 | 2012-02-08 | Philips Intellectual Property & Standards GmbH | Particle-based matrix carriers for mass spectrometry |
| CN102397564B (zh) * | 2010-09-19 | 2013-05-29 | 复旦大学 | 一种肿瘤靶向诊断核磁共振造影剂及其制备方法 |
| US10175170B2 (en) | 2010-12-16 | 2019-01-08 | The Regents Of The University Of California | Metal coating of rare earth nano-phosphors and uses thereof |
| CN102167813B (zh) * | 2011-01-19 | 2012-08-08 | 兰州大学 | 一种荧光示踪纳米磁共振成像造影剂 |
| FI124029B (fi) * | 2011-03-24 | 2014-02-14 | Upm Kymmene Corp | Menetelmä mikrokapseleiden valmistamiseksi hemiselluloosasta |
| EP2952210A3 (en) * | 2011-04-07 | 2016-03-16 | Emory University | Compositions comprising saccharide binding moieties and methods for targeted therapy |
| RU2465010C1 (ru) * | 2011-06-08 | 2012-10-27 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Контрастное средство для магнитно-резонансной томографии |
| CN102861346A (zh) * | 2011-07-08 | 2013-01-09 | 复旦大学附属肿瘤医院 | 细胞凋亡PET/CT活体分子影像探针18F-Annexin B1及其制备方法和用途 |
| CN102881392A (zh) * | 2011-07-15 | 2013-01-16 | 北京格加纳米技术有限公司 | 一种功能化磁性颗粒及其合成方法 |
| JP2014526517A (ja) | 2011-09-14 | 2014-10-06 | ノースウェスタン ユニバーシティ | 血液脳関門を通過することができるナノ抱合体 |
| CN102430130B (zh) * | 2011-11-24 | 2012-12-12 | 北京化工大学 | 一种医药用改性葡聚糖包覆磁性纳米颗粒复合材料及其制备方法 |
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| CN103159841B (zh) * | 2013-03-18 | 2014-07-02 | 江苏省原子医学研究所 | 一种99mTc标记Cys-Annexin V的方法及其应用 |
| CN103159842B (zh) * | 2013-03-18 | 2015-07-01 | 江苏省原子医学研究所 | 一种用于99mTc标记的Cys-Annexin V药盒及其配制方法与应用 |
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| US11213593B2 (en) | 2014-11-21 | 2022-01-04 | Northwestern University | Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates |
| CN104491881A (zh) * | 2014-12-05 | 2015-04-08 | 北京肿瘤医院 | 一种荧光偶联的特异性前哨淋巴结显像剂及其制备方法 |
| CN104758954B (zh) * | 2015-03-16 | 2017-08-25 | 北京化工大学 | 一种基于金属离子诱导多肽自组装的双功能纳米复合球及其制备方法 |
| GB2541003A (en) * | 2015-08-05 | 2017-02-08 | Kran Life Sciences Llp | Neurodegenerative disorders |
| CN105097174B (zh) * | 2015-08-12 | 2018-06-22 | 华南理工大学 | 一种木聚糖季铵盐纳米磁性颗粒及其制备方法 |
| KR101852066B1 (ko) * | 2016-09-09 | 2018-04-27 | 한국과학기술연구원 | 불소계 용매에 대한 분산성이 향상된 자성 나노입자 및 이의 제조방법 |
| CN107224588B (zh) * | 2016-11-08 | 2020-03-17 | 暨南大学 | 一种具有磁-pH值双响应的药物载体的制备方法 |
| CN108245689A (zh) * | 2016-12-29 | 2018-07-06 | 国家纳米科学中心 | 用于提高核磁共振检测精确度的造影剂、制备方法及应用 |
| CN107324399B (zh) * | 2017-07-12 | 2019-04-23 | 海门市彼维知识产权服务有限公司 | 一种氧化铁纳米材料和用作肿瘤药物靶向载体的用途 |
| CN107469092A (zh) * | 2017-08-07 | 2017-12-15 | 上海纳米技术及应用国家工程研究中心有限公司 | 靶向性纳米材料制备方法及其产品和应用 |
| CN108570081B (zh) * | 2018-05-25 | 2020-06-30 | 西南医科大学附属医院 | 一种葡萄糖类影像诊断及治疗的配体化合物及制备和应用 |
| CN111024683B (zh) * | 2019-12-26 | 2021-05-07 | 湖南大学 | 一种化学发光体系及其制备方法和应用 |
| CN111326302B (zh) * | 2020-03-23 | 2021-10-29 | 南通三优佳磁业有限公司 | 一种用于工业清洁空气的核壳结构磁性材料及制备方法 |
| CN111729093B (zh) * | 2020-06-29 | 2022-05-24 | 南京超维景生物科技有限公司 | 一种造影剂成膜剂组合物、造影剂成膜脂液、造影剂及其制备方法 |
| CA3190518A1 (en) * | 2020-08-06 | 2022-02-10 | Adiposs SA | Pet-ct imaging methods, contrast agents and pharmaceutical compositions for use in said imaging methods |
| CN112940157B (zh) * | 2021-03-22 | 2023-01-10 | 南方医科大学 | 一种钆螯合物及其制备方法和应用 |
| TWI886408B (zh) * | 2021-09-09 | 2025-06-11 | 原創生醫股份有限公司 | 用於超音波造影之金屬複合物及其用途 |
| CN115825442B (zh) * | 2021-11-23 | 2024-12-24 | 中国人民解放军总医院第一医学中心 | 钙钛矿纳米晶在制备用于肿瘤诊断或治疗的探针中的应用 |
| CN116077685B (zh) * | 2023-02-17 | 2024-11-26 | 成都纽瑞特医疗科技股份有限公司 | 放射性核素标记的含硼药物及其制备和应用 |
| CN120037403B (zh) * | 2025-02-11 | 2026-03-17 | 浙江大学医学院附属邵逸夫医院 | 一种ros响应载药双靶向治疗糖尿病肾病纳米递送系统的制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992017215A1 (en) * | 1990-03-28 | 1992-10-15 | Nycomed Salutar, Inc. | Contrast media |
| DE4117782C2 (de) * | 1991-05-28 | 1997-07-17 | Diagnostikforschung Inst | Nanokristalline magnetische Eisenoxid-Partikel, Verfahren zu ihrer Herstellung sowie diagnostische und/oder therapeutische Mittel |
| WO1994020148A1 (en) * | 1993-03-12 | 1994-09-15 | Mallinckrodt Medical, Inc. | Imidazole based nitrogen-sulfur ligands useful in radiographic imaging agents |
| US6333110B1 (en) * | 1998-11-10 | 2001-12-25 | Bio-Pixels Ltd. | Functionalized nanocrystals as visual tissue-specific imaging agents, and methods for fluorescence imaging |
| WO2005032598A1 (en) * | 2003-10-02 | 2005-04-14 | The General Hospital Corporation | Polybiotin compounds for magnetic resonance imagining and drug delivery |
-
2005
- 2005-12-12 US US11/721,382 patent/US20090238767A1/en not_active Abandoned
- 2005-12-12 JP JP2007546265A patent/JP2008524202A/ja active Pending
- 2005-12-12 RU RU2007127314/15A patent/RU2007127314A/ru not_active Application Discontinuation
- 2005-12-12 EP EP05825688A patent/EP1827506A2/en not_active Withdrawn
- 2005-12-12 BR BRPI0518952-7A patent/BRPI0518952A2/pt not_active Application Discontinuation
- 2005-12-12 WO PCT/IB2005/054185 patent/WO2006064451A2/en not_active Ceased
- 2005-12-12 CN CN200580043039.0A patent/CN101080240A/zh active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117883596A (zh) * | 2022-10-09 | 2024-04-16 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种乏氧响应的t1-t2可切换型mri造影剂、其制备方法及应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2007127314A (ru) | 2009-01-27 |
| EP1827506A2 (en) | 2007-09-05 |
| CN101080240A (zh) | 2007-11-28 |
| JP2008524202A (ja) | 2008-07-10 |
| WO2006064451A2 (en) | 2006-06-22 |
| US20090238767A1 (en) | 2009-09-24 |
| WO2006064451A3 (en) | 2007-03-01 |
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