BRPI0519705A2 - composiÇÕes, proteÍnas de fusço e mÉtodos de estimular uma resposta imune em um indivÍduo - Google Patents

composiÇÕes, proteÍnas de fusço e mÉtodos de estimular uma resposta imune em um indivÍduo

Info

Publication number
BRPI0519705A2
BRPI0519705A2 BRPI0519705-8A BRPI0519705A BRPI0519705A2 BR PI0519705 A2 BRPI0519705 A2 BR PI0519705A2 BR PI0519705 A BRPI0519705 A BR PI0519705A BR PI0519705 A2 BRPI0519705 A2 BR PI0519705A2
Authority
BR
Brazil
Prior art keywords
compositions
fusion proteins
individual
immune response
stimulating
Prior art date
Application number
BRPI0519705-8A
Other languages
English (en)
Inventor
Thomas J Powell
Valerian Nakkar
Langzhou Song
William F Mcdonald
Duane D Hewitt
Original Assignee
Vaxinnate Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxinnate Corp filed Critical Vaxinnate Corp
Publication of BRPI0519705A2 publication Critical patent/BRPI0519705A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSIÇÕES, PROTEÍNAS DE FUSIO E METODOS DE ESTIMULAR UMA RESPOSTA IMUNE EM UM INDIVÍDUO. Trata-se de composições, proteínas de fusão e polipeptídeos que compreendem pelo menos um padrão molecular associado a patógeno e pelo menos uma parte de pelo menos uma proteína de membrana integral de um antigeno viral de influenza. As composições, proteínas de fusão e polipeptídeos são usadas para estimular uma resposta imune em um indivíduo.
BRPI0519705-8A 2004-12-21 2005-12-21 composiÇÕes, proteÍnas de fusço e mÉtodos de estimular uma resposta imune em um indivÍduo BRPI0519705A2 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US63825404P 2004-12-21 2004-12-21
US63835004P 2004-12-21 2004-12-21
US64506705P 2005-01-19 2005-01-19
US65320705P 2005-02-15 2005-02-15
US66687805P 2005-03-31 2005-03-31
US68207705P 2005-05-18 2005-05-18
US74120205P 2005-11-30 2005-11-30
PCT/US2005/046662 WO2006069262A2 (en) 2004-12-21 2005-12-21 Compositions of influenza viral proteins and methods of use thereof

Publications (1)

Publication Number Publication Date
BRPI0519705A2 true BRPI0519705A2 (pt) 2009-03-10

Family

ID=36272492

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0519705-8A BRPI0519705A2 (pt) 2004-12-21 2005-12-21 composiÇÕes, proteÍnas de fusço e mÉtodos de estimular uma resposta imune em um indivÍduo

Country Status (9)

Country Link
EP (1) EP1831259A2 (pt)
JP (1) JP2008524261A (pt)
AU (2) AU2005319141B8 (pt)
BR (1) BRPI0519705A2 (pt)
CA (1) CA2593746A1 (pt)
MX (1) MX2007007586A (pt)
NZ (1) NZ556004A (pt)
SG (1) SG160424A1 (pt)
WO (1) WO2006069262A2 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2594612A1 (en) 2005-01-19 2006-07-27 Vaxinnate Corporation Compositions comprising pathogen-associated molecular patterns and antigens and their use to stimulate an immune response
ES2555544T3 (es) 2006-03-07 2016-01-04 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
WO2007127290A2 (en) * 2006-04-24 2007-11-08 Protelix, Inc. Method for producing viral vaccine and therapeutic peptide antigens
EP2857038B1 (en) * 2006-09-18 2019-04-10 The Board of Trustees of the University of Arkansas Compositions and methods of enhancing immune responses
EP1925318A1 (en) * 2006-11-20 2008-05-28 Paul-Ehrlich-Institut Recombinant modified vaccinia virus Ankara (MVA)-based vaccine for the avian flu
US8778847B2 (en) * 2007-06-13 2014-07-15 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Immunogenic peptides of influenza virus
PL2173376T3 (pl) 2007-08-02 2015-08-31 Biondvax Pharmaceuticals Ltd Multimeryczne wieloepitopowe szczepionki przeciwko grypie
GB0720250D0 (en) 2007-10-17 2007-11-28 Univ Edinburgh Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof
EP2223934B1 (en) * 2007-11-14 2012-10-03 Institute Of Microbiology, Chinese Academy Of Sciences Polypeptides for inhibiting influenza virus infection
AU2009236585B2 (en) 2008-04-18 2013-03-07 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
JP2012523379A (ja) 2009-04-09 2012-10-04 ザ ユニバーシティー オブ メルボルン 免疫原性組成物およびその使用
MX348663B (es) * 2009-09-08 2017-05-26 Inst Tecnologico Estudios Superiores Monterrey Proceso de producción de una vacuna recombinante, dicha vacuna expresable en cepas de escherichia coli y su uso para combatir la influenza a h1ni1 brote 2009.
EP2521563B1 (en) * 2010-01-06 2016-12-07 VaxInnate Corporation Compositions for providing protective immunity in the elderly
NO2525817T3 (pt) 2010-01-21 2018-01-06
CN103118709A (zh) * 2010-03-26 2013-05-22 新兴产品开发盖瑟斯堡有限公司 流感病毒基质2蛋白的胞外域、其表达系统和应用
GB201009273D0 (en) * 2010-06-03 2010-07-21 Glaxosmithkline Biolog Sa Novel vaccine
WO2012037612A1 (en) 2010-09-22 2012-03-29 The University Of Melbourne Novel immunostimulatory method
CA2828068C (en) 2011-02-22 2019-03-19 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
HK1208355A1 (en) 2012-11-05 2016-03-04 Georgia State University Research Foundation, Inc. Universal influenza vaccine based on heterologous multiple m2e proteins
RU2571944C1 (ru) * 2014-10-17 2015-12-27 Общество с ограниченной ответственностью "НТфарма" Противогриппозная вакцина широкого спектра действия против птичьего гриппа а на основе эктодомена белка м2
PL3728289T3 (pl) 2017-12-21 2026-01-26 Axelia Oncology Pty Ltd Zoptymalizowane związki
JP2022539091A (ja) 2019-06-26 2022-09-07 アクセリア オンコロジー ピーティーワイ リミテッド 新規な分子
WO2023028661A1 (en) * 2021-09-02 2023-03-09 Ena Respiratory Pty Ltd Formulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0313154A (pt) * 2002-08-12 2005-08-02 Council The Queensland Inst Of Novos lipopeptìdeos imunogênicos que compreendem epitopos de célula t-helper e de célula b
BRPI0407877A (pt) * 2003-03-07 2006-03-01 Merck & Co Inc conjugado de peptìdeo-proteìna, vacina para a prevenção ou melhora da infecção pelo vìrus influenza, e, método para induzir um resposta imune em um paciente

Also Published As

Publication number Publication date
MX2007007586A (es) 2007-12-10
AU2005319141A1 (en) 2006-06-29
WO2006069262A3 (en) 2007-02-01
CA2593746A1 (en) 2006-06-29
WO2006069262A2 (en) 2006-06-29
JP2008524261A (ja) 2008-07-10
SG160424A1 (en) 2010-04-29
EP1831259A2 (en) 2007-09-12
AU2010200048A1 (en) 2010-01-28
AU2005319141B2 (en) 2010-02-18
NZ556004A (en) 2010-05-28
AU2005319141B8 (en) 2010-03-18

Similar Documents

Publication Publication Date Title
MX2007007586A (es) Composiciones de proteinas de virus de gripe y metodos de uso de las mismas.
CY1123952T1 (el) Απομονωση και καθαρισμος αντισωματων αντι-il-13 με την χρηση χρωματογραφιας χημικης συγγενειας πρωτεινης α
HN2006016512A (es) Anticuerpos anti-il-6, composiciones, metodos y usos
DK1939281T4 (da) Immortaliserede andecellelinjer til virusproduktion
CY1117162T1 (el) Μεθοδος κατασκευης αντισωματος fc-ετεροδιμερικων μοριων χρησιμοποιωντας αποτελεσματα ηλεκτροστατικης καθοδηγησης
AR057614A1 (es) Composiciones y metodos para producir moleculas de union con antigeno hibridas y usos de las mismas
BRPI0606479A (pt) composições; proteìnas de fusão; polipepitìdeos; e métodos para estimular uma resposta imune em um indivìduo
NO20063026L (no) Antistoffer
AR038568A1 (es) Anticuerpos anti-a beta y su uso
BRPI0508935A (pt) agonistas de receptor seletivo y4 para intervenções terapêuticas
EA201100070A1 (ru) Туберкулезный белок rv2386c, композиции и их применения
BRPI0515649B8 (pt) Processo para preparação de composições de anticorpo monoclonal altamente concentradas
AR070690A1 (es) Metodos y composiciones que utilizan polipeptidos de fusion de klotho-fgf (factor de crecimiento de fibroblastos)
ATE529442T1 (de) Verbesserte humane interferon-moleküle und ihre verwendungen
WO2007047829A3 (en) Novel heterodimeric proteins and uses thereof
DK1423419T3 (da) Hybrid- og tandemekspression af Neisseria-proteiner
IL187168A (en) Proteins or polypeptides which comprise two identical nanobodies against von willebrand factor, methods for their preparation, pharmaceutical compositions comprising them and their uses
MY206284A (en) Anti-cd63 antibodies, conjugates, and uses thereof
ATE539089T1 (de) Cyclische rezeptor-assoziierte-proteine (rap)- peptide
WO2010074575A3 (en) Recombinant classical swine fever virus (csfv) comprising a modified e2 protein and methods for generating said recombinant csfv.
MXPA05009580A (es) Vacuna contra el virus de la influenza.
EP4374913A3 (en) Novel human serum albumin mutant
BR112022026580A2 (pt) Composições e métodos para induzir uma resposta imune contra coronavírus
NO20062709L (no) Stamceller som er egnet for transplantasjon, fremstilling derav og farmasoytiske preperater omfattende nevnte stamceller
AR042968A1 (es) Anticuerpos de virus anti-dengue composiciones metodos y usos

Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 6A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.