BRPI0519712A2 - modificador superficial de (polialcàxi)-sulfonatos - Google Patents

modificador superficial de (polialcàxi)-sulfonatos

Info

Publication number
BRPI0519712A2
BRPI0519712A2 BRPI0519712-0A BRPI0519712A BRPI0519712A2 BR PI0519712 A2 BRPI0519712 A2 BR PI0519712A2 BR PI0519712 A BRPI0519712 A BR PI0519712A BR PI0519712 A2 BRPI0519712 A2 BR PI0519712A2
Authority
BR
Brazil
Prior art keywords
compounds
present
surfactants
methods
pharmaceutical
Prior art date
Application number
BRPI0519712-0A
Other languages
English (en)
Inventor
James E Kipp
Ton That Hai
Bennett P Melnick
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of BRPI0519712A2 publication Critical patent/BRPI0519712A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
    • C08G65/326—Polymers modified by chemical after-treatment with inorganic compounds containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyethers (AREA)

Abstract

MODIFICADOR SUPERFICIAL DE (POLIALCàXI)-SULFONATOS. A presente invenção refere-se a compostos inusitados, métodos para fabricar e métodos de uso. A presente invenção refere-se também a partículas sólidas de agentes farmacêuticos ativos, que têm um ou mais dos compostos da presente invenção associados com a superfície dos mesmos. Os compostos da presente invenção compreendem um poliéter apoiar ligado de forma covalente a um grupo sulfonato anjônico. Os compostos têm um caráter anfifílico e, de preferência, são tensoativos. Tais compostos são, de preferência, úteis como agentes tensoativos para revestir e estabilizar dispersões de partículas em um meio liquido contínuo. Estes agentes tensoativos podem ser aplicados na estabilização de suspensões, emulsões, ou formulações de lipossomas, intencionadas para uso farmacêutico, médico, cosmético ou agrícola. As partículas que podem ser preparadas por uma série de métodos e irão, de preferência, compreender um agente farmacêutico. As composições farmacêuticas da presente invenção podem ser usadas para tratar uma miríade de condições, e podem ser administradas por muitas vias, incluindo via intravenosa, intramuscular, subcutânea, intratecal, subdural, intacameral, intracerebral, intralesional, tópica, oral, bucal, retal, pulmonar, e nasal.
BRPI0519712-0A 2004-12-21 2005-12-15 modificador superficial de (polialcàxi)-sulfonatos BRPI0519712A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63806704P 2004-12-21 2004-12-21
PCT/US2005/045321 WO2006081000A2 (en) 2004-12-21 2005-12-15 (polyalkoxy)sulfonate surface modifiers

Publications (1)

Publication Number Publication Date
BRPI0519712A2 true BRPI0519712A2 (pt) 2009-03-10

Family

ID=36608726

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0519712-0A BRPI0519712A2 (pt) 2004-12-21 2005-12-15 modificador superficial de (polialcàxi)-sulfonatos

Country Status (8)

Country Link
US (1) US7776360B2 (pt)
EP (1) EP1833877A2 (pt)
JP (1) JP2008524393A (pt)
AU (1) AU2005326168A1 (pt)
BR (1) BRPI0519712A2 (pt)
CA (1) CA2591554A1 (pt)
MX (1) MX2007007442A (pt)
WO (1) WO2006081000A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009015397A1 (en) * 2007-07-26 2009-01-29 Nanoscan Imaging, Llc Methods for imaging using improved nanoparticulate contrast agents
DK2200588T3 (da) * 2007-09-25 2019-07-01 Solubest Ltd Sammensætninger, som omfatter lipofile aktive forbindelser, og fremgangsmåde til fremstilling deraf
AU2012332894A1 (en) * 2011-10-31 2014-05-08 Merck Sharp & Dohme Corp. Nano-suspension process
WO2014112586A1 (ja) * 2013-01-18 2014-07-24 株式会社クラレ ポリオキシアルキレン変性ビニルアルコール系重合体を含有する組成物
HRP20250718T1 (hr) * 2016-08-15 2025-08-15 F. Hoffmann-La Roche Ag Kromatografski postupak za kvantifikaciju neionskog surfaktanta u sastavu koji sadrži neionski surfaktant i polipeptid
WO2020123129A1 (en) 2018-12-11 2020-06-18 Dow Global Technologies Llc Aqueous solutions of poorly soluble active ingredients using polyalkyoxylated amino alcohols
BR112021008954A2 (pt) 2018-12-11 2021-08-10 Dow Global Technologies Llc composição, e, método
CN112592706B (zh) * 2020-12-03 2022-11-29 西安长庆化工集团有限公司 一种压裂用驱油剂及其制备方法和应用
CN115466343B (zh) * 2021-06-11 2023-10-27 中昊晨光化工研究院有限公司 一种聚醚二酸或其盐类表面活性剂及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014537A1 (de) * 1990-05-07 1991-11-14 Goldschmidt Ag Th Verfahren zur herstellung von hochelastischen, polyurethangruppen aufweisenden schaumstoffen mit verminderter stauchhaerte
DE4202187A1 (de) * 1992-01-28 1993-07-29 Goldschmidt Ag Th Polyacrylsaeureester mit ethersulfonatgruppen
US5739212A (en) * 1992-12-08 1998-04-14 Skw Trostberg Aktiengesellschaft Water-soluble graft polymers
DE69325391T2 (de) * 1993-01-20 2000-02-24 Agfa-Gevaert N.V., Mortsel Fotopolymerisierbare Zusammensetzung mit hoher Empfindlichkeit und dieseZusammensetzung verwendendes Vefahren zum Herstellen von Bildern
US5569448A (en) 1995-01-24 1996-10-29 Nano Systems L.L.C. Sulfated nonionic block copolymer surfactants as stabilizer coatings for nanoparticle compositions
US5718919A (en) * 1995-02-24 1998-02-17 Nanosystems L.L.C. Nanoparticles containing the R(-)enantiomer of ibuprofen
JP4484247B2 (ja) * 1995-02-24 2010-06-16 エラン ファーマ インターナショナル，リミティド ナノ粒子分散体を含有するエアロゾル
US5565188A (en) * 1995-02-24 1996-10-15 Nanosystems L.L.C. Polyalkylene block copolymers as surface modifiers for nanoparticles

Also Published As

Publication number Publication date
WO2006081000A3 (en) 2006-09-28
US20060141048A1 (en) 2006-06-29
CA2591554A1 (en) 2006-08-03
WO2006081000A9 (en) 2006-08-31
JP2008524393A (ja) 2008-07-10
EP1833877A2 (en) 2007-09-19
AU2005326168A1 (en) 2006-08-03
MX2007007442A (es) 2007-08-15
US7776360B2 (en) 2010-08-17
WO2006081000A2 (en) 2006-08-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B25G Requested change of headquarter approved

Owner name: BAXTER INTERNATIONAL INC. (US) , BAXTER HEALTHCARE

Free format text: ENDERECO DO 1O DEPOSITANTE ALTERADO CONFORME SOLICITADO NA PETICAO NO 020110115944/RJ DE 11/11/2011.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 6A ANUIDADE.