BRPI0519959A2 - copolìmero de (met)acrilato aniÈnico parcialmente neutralizado - Google Patents

copolìmero de (met)acrilato aniÈnico parcialmente neutralizado

Info

Publication number
BRPI0519959A2
BRPI0519959A2 BRPI0519959-0A BRPI0519959A BRPI0519959A2 BR PI0519959 A2 BRPI0519959 A2 BR PI0519959A2 BR PI0519959 A BRPI0519959 A BR PI0519959A BR PI0519959 A2 BRPI0519959 A2 BR PI0519959A2
Authority
BR
Brazil
Prior art keywords
meth
acrylate copolymer
anionic
neutralized anionic
weight
Prior art date
Application number
BRPI0519959-0A
Other languages
English (en)
Inventor
Rosario Lizio
Hans-Ulrich Petereit
Erna Roth
Michael Damm
Ruediger Alexowsky
Original Assignee
Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm Gmbh filed Critical Roehm Gmbh
Publication of BRPI0519959A2 publication Critical patent/BRPI0519959A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C08F220/1802—C2-(meth)acrylate, e.g. ethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
    • C08L33/08—Homopolymers or copolymers of acrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
    • C08L33/10—Homopolymers or copolymers of methacrylic acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

COPOLìMERO DE (MET)ACRILATO ANIÈNICO PARCIALMENTE NEUTRALIZADO. A presente invenção refere-se a um copolímero de (met)acrilato aniónico parcialmente neutralizado consistindo em unidades polimerizadas com radical contendo 25-95% em peso de C14 alquil ésteres de ácido (met)acrílico e 5-75% em peso de monómero (met)acrilato com um grupo aniónico, onde 0,1 a 25% de grupos aniónicos contidos são neutralizados por uma base. A dita invenção é caracterizada em que a dita base é realizada na forma de uma base orgânica catiónica cujo peso molecular é maior que 150. Uma forma médica contendo o dito copolímero de (met)acrilato aniónico parcialmente neutralizado e o uso do dito copolímero de (met)acrilato aniónico parcialmente neutralizado para produção de uma forma médica liberando rapidamente uma substância ativa tendo um determinado valor de pH também são mostrados.
BRPI0519959-0A 2005-02-15 2005-12-15 copolìmero de (met)acrilato aniÈnico parcialmente neutralizado BRPI0519959A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005007059A DE102005007059A1 (de) 2005-02-15 2005-02-15 Teilneutralisiertes anionisches (Meth)acrylat-Copolymer
PCT/EP2005/013513 WO2006087027A1 (de) 2005-02-15 2005-12-15 Teilneutralisiertes anionisches (meth)acrylat-copolymer

Publications (1)

Publication Number Publication Date
BRPI0519959A2 true BRPI0519959A2 (pt) 2009-04-07

Family

ID=35809632

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0519959-0A BRPI0519959A2 (pt) 2005-02-15 2005-12-15 copolìmero de (met)acrilato aniÈnico parcialmente neutralizado

Country Status (16)

Country Link
US (1) US8431157B2 (pt)
EP (1) EP1848751B1 (pt)
JP (1) JP5032341B2 (pt)
KR (2) KR20070111483A (pt)
CN (1) CN101103055B (pt)
AT (1) ATE471954T1 (pt)
BR (1) BRPI0519959A2 (pt)
CA (1) CA2597800C (pt)
DE (2) DE102005007059A1 (pt)
ES (1) ES2347342T3 (pt)
IL (1) IL185218A (pt)
MX (1) MX2007009502A (pt)
PL (1) PL1848751T3 (pt)
SI (1) SI1848751T1 (pt)
TW (1) TW200635963A (pt)
WO (1) WO2006087027A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10333443A1 (de) * 2003-07-23 2005-02-10 Goldschmidt Ag Emulgator für dünnflüssige W/O-Emulsionen auf Basis von teilvernetzten Polyglycerinestern der Polyhydroxystearinsäure
DE102005032806A1 (de) 2005-07-12 2007-01-18 Röhm Gmbh Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten
DE102006035549A1 (de) * 2006-07-27 2008-01-31 Evonik Röhm Gmbh Arzneiform mit mindestens zweischichtiger Trennschicht
LT2152250T (lt) * 2007-05-07 2019-12-27 Evonik Operations Gmbh Kietos dozavimo formos, apimančios enterinę dangą su pagreitintu vaisto atpalaidavimu
JP5281358B2 (ja) * 2008-10-27 2013-09-04 学校法人常翔学園 高分子、経上皮吸収促進剤、及び医薬用製剤
US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
US8859697B2 (en) 2010-10-13 2014-10-14 Evonik Röhm Gmbh Process for preparing a (meth)acrylate copolymer containing tertiary amino groups by free-radical polymerization in solution
CA2885680C (en) 2011-09-07 2022-10-04 Roland Saur-Brosch Formulation for the controlled release of one or several substances in the digestive tract of a mammal.
CN103342974B (zh) * 2013-07-05 2016-04-13 中国科学院青岛生物能源与过程研究所 一种仿贻贝蛋白环保型锂离子电池粘合剂
WO2016066249A1 (en) * 2014-10-28 2016-05-06 Merck Patent Gmbh Preparation of nanoparticles-releasing enteric microparticles
DE102018129419A1 (de) * 2018-11-22 2020-05-28 Johannes Gutenberg-Universität Mainz Acrylat-Copolymer für galenische Anwendungen
CA3121333A1 (en) * 2018-12-05 2020-06-11 Evonik Operations Gmbh Process for preparing polymeric particles
DE102019135432A1 (de) * 2019-12-20 2021-06-24 Lts Lohmann Therapie-Systeme Ag Lösliche Rückschicht für OTF
DE102021107829A1 (de) * 2021-03-29 2022-09-29 Lts Lohmann Therapie-Systeme Ag. Oraler Dünnfilm
CN113929807B (zh) * 2021-06-25 2022-09-27 贵州省欣紫鸿药用辅料有限公司 一种烯烃酸树脂及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208791A1 (de) * 1982-03-11 1983-09-22 Röhm GmbH, 6100 Darmstadt Verfahren zum ueberziehen von arzneiformen mittes eines in wasser dispergierten ueberzugsmittels
US5160737A (en) 1988-05-03 1992-11-03 Perio Products Ltd. Liquid polymer composition, and method of use
US5438076A (en) * 1988-05-03 1995-08-01 Perio Products, Ltd. Liquid polymer composition, and method of use
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
EP0520119A1 (de) * 1991-06-17 1992-12-30 Spirig Ag Pharmazeutische Präparate Neue orale Diclofenaczubereitung
WO1994018834A1 (en) * 1993-02-16 1994-09-01 Virginia Tech Intellectual Properties, Inc. Polyelectrolyte dna conjugation and genetic transformation of an animal
FR2706126B1 (fr) * 1993-06-08 1995-07-21 Oreal Composition cosmétique contenant un pseudo-latex ayant des propriétés de rémanence.
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
DE10220470A1 (de) * 2002-04-30 2003-11-20 Roehm Gmbh ph-sensitives Polymer
CN1545421A (zh) * 2001-06-22 2004-11-10 �Ʒ� 包含低溶解度和/或酸敏感的药物以及中和的酸性聚合物的药物组合物
DE10208335A1 (de) * 2002-02-27 2003-09-04 Roehm Gmbh Arzneiform und Verfahren zu ihrer Herstellung
DE10250543A1 (de) * 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
MXPA04010956A (es) * 2003-01-30 2005-01-25 Roehm Gmbh Forma de dosis farmaceutica y metodo para la produccion de la misma.
CN1784436B (zh) * 2003-03-07 2010-06-02 巴斯福股份公司 聚合物制品
DE10332160A1 (de) 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
DE10353186A1 (de) 2003-11-13 2005-06-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz
DE10353196A1 (de) 2003-11-13 2005-06-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform mit einer die Abgabe einer modulatorischen Substanz beeinflussenden Matrix
JP2007517038A (ja) * 2003-12-30 2007-06-28 ドクター レディズ ラボラトリーズ リミテッド 薬学的組成物
DE102004036437A1 (de) 2004-07-27 2006-03-23 Röhm GmbH & Co. KG Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
ES2385498T3 (es) 2006-08-18 2012-07-25 Evonik Röhm Gmbh Composición farmacéutica con liberación controlada de la sustancia activa, para sustancias activas con una buena solubilidad en agua

Also Published As

Publication number Publication date
SI1848751T1 (sl) 2010-10-29
WO2006087027A1 (de) 2006-08-24
CN101103055A (zh) 2008-01-09
DE502005009807D1 (de) 2010-08-05
CN101103055B (zh) 2011-04-20
JP5032341B2 (ja) 2012-09-26
CA2597800C (en) 2012-10-23
MX2007009502A (es) 2007-09-21
PL1848751T3 (pl) 2010-11-30
EP1848751A1 (de) 2007-10-31
US8431157B2 (en) 2013-04-30
CA2597800A1 (en) 2006-08-24
IL185218A0 (en) 2008-02-09
TW200635963A (en) 2006-10-16
KR20070111483A (ko) 2007-11-21
ATE471954T1 (de) 2010-07-15
JP2008530319A (ja) 2008-08-07
EP1848751B1 (de) 2010-06-23
US20090041842A1 (en) 2009-02-12
IL185218A (en) 2012-10-31
ES2347342T3 (es) 2010-10-28
KR20130042644A (ko) 2013-04-26
DE102005007059A1 (de) 2006-08-24

Similar Documents

Publication Publication Date Title
IL185218A0 (en) Partly neutralised anionic (meth) acrylate copolymer
FR2873702B1 (fr) Copolymere hyperbranche comprenant des monomeres selectionnes, composition le comprenant, et procede cosmetique
WO2007006353A3 (de) Verwendung eines teilneutralisierten, anionischen (meth) acrylat-copolymers als uberzug fur die herstellung einer arzneiform mit einer wirkstofffreisetzung bei erniedrigten ph-werten
EP1931806A4 (en) PKR ACTIVATION BY HYBRIDIZATION CHAIN REACTION
AR061978A1 (es) Polimeros
AR047540A1 (es) Particulados
AU2003266351A1 (en) Multilayer dosage forms, which contain active substances and which comprise a neutral core, and an inner and outer coating consisting of methacrylate copolymers and methacrylate monomers
ATE474563T1 (de) Hydrogelzusammensetzung zur transdermalen arzneistoffabgabe
EP2363437A3 (en) Ink composition, ink set and image forming method
EP1794173A4 (en) AMPLIFICATION BLOCKERS COMPRISING INTERCALING NUCLEIC ACIDS (TNA) EMBEDDING INTERCALING PSEUDONUCLEOTIDES (IPN)
WO2007120707A3 (en) Polyamide composition comprising a modifier
UA95237C2 (uk) Імуногенна композиція
WO2009021728A3 (en) Targeted block copolymer micelles
FR2829383B1 (fr) Compositions cosmetiques contenant un copolymere d'acide methacrylique, une silicone et un polymere cationique et leurs utilisations
WO2005118008A3 (en) Compositions and articles containing a crosslinked polymer matrix and an immobilized active liquid, as well as methods of making and using the same
IL180849A (en) Medicament in a multilayer form
ATE327732T1 (de) Zusammensetzung für ein umformbares hairstyling, die heterogene(meth)acrylcopolymer-partikel enthält
ATE521373T1 (de) Knochenzementzusammensetzung
SG151263A1 (en) Water-soluble copolymer having alkyl-modified carboxyl groups
FR2868784B1 (fr) Copolymere sequence, composition le comprenant et procede de traitement cosmetique
EP1632508A3 (fr) Nouveaux copolymères éthyléniques, compositions les comprenant et procédé de traitement
DE502008002284D1 (de) Biologisch wirksame moleküle, insbesondere auf grundlage von pna und sirna, verfahren zu deren zellspezifischen aktivierung sowie applikationskit zur verabreichung
ATE474582T1 (de) Pharmazeutische zusammensetzung enthaltend glucan aus mikroalgen
BR0300817A (pt) Composição cosmética e processo de tratamento das matérias queratìnicas
TR200902782A1 (tr) Canlı aşı bileşimi

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: EVONIK ROEHM GMBH (DE)

Free format text: NOME ALTERADO DE: ROEHM GMBH

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.