BRPI0520902A2 - MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF THAT BINDS TO PSCA PROTEINS FOR CANCER DIAGNOSIS, METHOD FOR PRODUCING THE SAME, HIB'RIDOMA, POLYNUCLEOTIDE, VECTOR, CELL, COMPOSITION, ASSAY TO DETECT THE PRESENCE OF A PSCA PROTEIN AND METHOD FOR DETECTING A PSCA PROTEIN - Google Patents
MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF THAT BINDS TO PSCA PROTEINS FOR CANCER DIAGNOSIS, METHOD FOR PRODUCING THE SAME, HIB'RIDOMA, POLYNUCLEOTIDE, VECTOR, CELL, COMPOSITION, ASSAY TO DETECT THE PRESENCE OF A PSCA PROTEIN AND METHOD FOR DETECTING A PSCA PROTEINInfo
- Publication number
- BRPI0520902A2 BRPI0520902A2 BRPI0520902A BRPI0520902A2 BR PI0520902 A2 BRPI0520902 A2 BR PI0520902A2 BR PI0520902 A BRPI0520902 A BR PI0520902A BR PI0520902 A2 BRPI0520902 A2 BR PI0520902A2
- Authority
- BR
- Brazil
- Prior art keywords
- psca
- psca protein
- ridoma
- hib
- polynucleotide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/857,484 US7622564B2 (en) | 2003-05-30 | 2004-05-28 | Prostate stem cell antigen (PSCA) variants and subsequences thereof |
| PCT/US2004/017231 WO2005014780A2 (en) | 2003-05-30 | 2004-05-28 | Prostate stem cell antigen (psca) variants and subsequences thereof |
| US61638104P | 2004-10-05 | 2004-10-05 | |
| US60/616,381 | 2004-10-05 | ||
| US61788104P | 2004-10-12 | 2004-10-12 | |
| US60/617,881 | 2004-10-12 | ||
| US62131004P | 2004-10-21 | 2004-10-21 | |
| US60/621,310 | 2004-10-21 | ||
| US63307704P | 2004-12-02 | 2004-12-02 | |
| US60/633,077 | 2004-12-02 | ||
| US67200005P | 2005-04-14 | 2005-04-14 | |
| US60/672,000 | 2005-04-14 | ||
| BRPI0511624-4A BRPI0511624B1 (en) | 2004-05-28 | 2005-05-17 | MONOCLONAL ANTIBODY THAT BINDS TO PSCA PROTEIN, USE OF IT, HYBRIDOMA, VECTOR, PHARMACEUTICAL COMPOSITION, AS WELL AS ASSAY AND METHOD FOR DETECTION OF THE PRESENCE OF A PSCA PROTEIN IN A BIOLOGICAL SAMPLE |
| PCT/US2005/017412 WO2005118864A2 (en) | 2004-05-28 | 2005-05-17 | Antibodies and related molecules that bind to psca proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0520902A2 true BRPI0520902A2 (en) | 2011-10-25 |
| BRPI0520902B1 BRPI0520902B1 (en) | 2021-11-30 |
Family
ID=44210117
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0511624-4A BRPI0511624B1 (en) | 2004-05-28 | 2005-05-17 | MONOCLONAL ANTIBODY THAT BINDS TO PSCA PROTEIN, USE OF IT, HYBRIDOMA, VECTOR, PHARMACEUTICAL COMPOSITION, AS WELL AS ASSAY AND METHOD FOR DETECTION OF THE PRESENCE OF A PSCA PROTEIN IN A BIOLOGICAL SAMPLE |
| BR122018073034-0A BR122018073034B1 (en) | 2004-05-28 | 2005-05-17 | ANTIBODIES AND RELATED MOLECULES THAT BIND TO PSCA PROTEINS |
| BRPI0520902-1A BRPI0520902B1 (en) | 2004-05-28 | 2005-05-17 | MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT OF THE SAME THAT BINDS TO PSCA PROTEINS FOR THE DIAGNOSIS OF CANCER, METHOD FOR PRODUCTION THEREOF, HYBRIDOMA, POLYNUCLEOTIDE, VECTOR, COMPOSITION, ASSAY TO DETECT THE PRESENCE OF A PSCA PROTEIN AND METHOD OF DETECTION OF ONE PSCA PROTEIN |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0511624-4A BRPI0511624B1 (en) | 2004-05-28 | 2005-05-17 | MONOCLONAL ANTIBODY THAT BINDS TO PSCA PROTEIN, USE OF IT, HYBRIDOMA, VECTOR, PHARMACEUTICAL COMPOSITION, AS WELL AS ASSAY AND METHOD FOR DETECTION OF THE PRESENCE OF A PSCA PROTEIN IN A BIOLOGICAL SAMPLE |
| BR122018073034-0A BR122018073034B1 (en) | 2004-05-28 | 2005-05-17 | ANTIBODIES AND RELATED MOLECULES THAT BIND TO PSCA PROTEINS |
Country Status (6)
| Country | Link |
|---|---|
| KR (2) | KR101282396B1 (en) |
| CN (1) | CN102344493B (en) |
| BR (3) | BRPI0511624B1 (en) |
| IL (1) | IL214210A (en) |
| NO (1) | NO341404B1 (en) |
| SI (1) | SI1753871T1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2442919T3 (en) | 2007-03-27 | 2014-02-14 | Immunovia Ab | Signature / protein markers for the detection of adenocarcinoma |
| TR201900694T4 (en) * | 2012-08-23 | 2019-02-21 | Agensys Inc | Antibody drug conjugates (ADC) that bind to 158p1d7 proteins. |
| BR112015013700A8 (en) | 2012-12-13 | 2020-02-18 | Inovio Pharmaceuticals Inc | composition, nucleotide sequence, synthetic antibody, and, use of the composition |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| EP3080159A4 (en) | 2013-12-13 | 2017-08-02 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
| CN107427566B (en) | 2014-12-01 | 2021-08-17 | 宾夕法尼亚大学理事会 | DNA antibody constructs and methods of use |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| CN119930826A (en) * | 2023-11-02 | 2025-05-06 | 重庆精准生物产业技术研究院有限公司 | Fully humanized single-chain antibody against PSCA and its application |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6258939B1 (en) * | 1997-03-10 | 2001-07-10 | The Regents Of The University Of California | PSCA antibodies and hybridomas producing them |
| US6267960B1 (en) * | 1997-03-10 | 2001-07-31 | The Regents Of The University Of California | PSCA: prostate stem cell antigen |
| US6541212B2 (en) * | 1997-03-10 | 2003-04-01 | The Regents Of The University Of California | Methods for detecting prostate stem cell antigen protein |
| JP4028237B2 (en) * | 1999-10-29 | 2007-12-26 | ジェネンテック・インコーポレーテッド | Anti-prostate stem cell antigen (PSCA) antibody composition and method of use |
-
2005
- 2005-05-17 SI SI200532000T patent/SI1753871T1/en unknown
- 2005-05-17 KR KR1020117010832A patent/KR101282396B1/en not_active Expired - Lifetime
- 2005-05-17 BR BRPI0511624-4A patent/BRPI0511624B1/en not_active IP Right Cessation
- 2005-05-17 BR BR122018073034-0A patent/BR122018073034B1/en active IP Right Grant
- 2005-05-17 CN CN201110118165.5A patent/CN102344493B/en not_active Expired - Lifetime
- 2005-05-17 BR BRPI0520902-1A patent/BRPI0520902B1/en active IP Right Grant
-
2006
- 2006-12-28 KR KR1020067027763A patent/KR101215611B1/en not_active Expired - Lifetime
-
2011
- 2011-04-29 NO NO20110647A patent/NO341404B1/en unknown
- 2011-07-20 IL IL214210A patent/IL214210A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| SI1753871T1 (en) | 2016-01-29 |
| BRPI0511624B1 (en) | 2022-02-08 |
| CN102344493B (en) | 2014-09-03 |
| BR122018073034B1 (en) | 2021-10-13 |
| KR20070047251A (en) | 2007-05-04 |
| IL214210A0 (en) | 2011-08-31 |
| KR101282396B1 (en) | 2013-07-04 |
| KR20110056564A (en) | 2011-05-30 |
| NO20110647L (en) | 2006-12-19 |
| BR122018073034B8 (en) | 2022-10-11 |
| BRPI0520902B1 (en) | 2021-11-30 |
| CN102344493A (en) | 2012-02-08 |
| NO341404B1 (en) | 2017-10-30 |
| KR101215611B1 (en) | 2012-12-28 |
| IL214210A (en) | 2013-01-31 |
| BRPI0511624A (en) | 2008-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 7A. ANUIDADE. |
|
| B08H | Application fees: decision cancelled [chapter 8.8 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 NA RPI 2204 DE 02/04/2013. |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/05/2005, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |