BRPI0600285A - compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticas - Google Patents
compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticasInfo
- Publication number
- BRPI0600285A BRPI0600285A BRPI0600285-4A BRPI0600285A BRPI0600285A BR PI0600285 A BRPI0600285 A BR PI0600285A BR PI0600285 A BRPI0600285 A BR PI0600285A BR PI0600285 A BRPI0600285 A BR PI0600285A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical compounds
- compounds useful
- nanoparticles
- treating restenosis
- nanoparticulate pharmaceutical
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 208000037803 restenosis Diseases 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 abstract 4
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
COMPOSTOS FARMACêUTICOS CONTENDO NANOPARTìCULAS úTEIS PARA TRATAMENTO DE LESõES REESTENóTICAS São descritos compostos farmacêuticos contendo nanopartículas úteis para tratamento de lesões reestenóticas que compreendem nanoparticulas de rapamicina (sirolimus) ou análogos e/ou nanoparticulas de paclitaxel ou análogos, isoladamente ou em associação, ditas nanoparticulas com ou sem revestimento catiónico.
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRC10600285-4A BRPI0600285C1 (pt) | 2006-01-13 | 2006-01-13 | compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticas |
| EP07701600A EP1978957A4 (en) | 2006-01-13 | 2007-01-12 | NANOTEILS CONTAINING PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF RESTENOTIC LESIONS |
| CA002636336A CA2636336A1 (en) | 2006-01-13 | 2007-01-12 | Pharmaceutical compounds that contain nanoparticles useful for treating restenotic lesions |
| JP2008549721A JP2009523133A (ja) | 2006-01-13 | 2007-01-12 | 再狭窄病変治療に有用なナノ粒子含有の薬化合物類 |
| CNA2007800017443A CN101365447A (zh) | 2006-01-13 | 2007-01-12 | 用于治疗再狭窄病变的含有纳米粒子的药物组合物 |
| AU2007204550A AU2007204550A1 (en) | 2006-01-13 | 2007-01-12 | Pharmaceutical compounds that contain nanoparticles useful for treating restenotic lesions |
| PCT/BR2007/000015 WO2007079560A2 (en) | 2006-01-13 | 2007-01-12 | Pharmaceutical compounds that contain nanoparticles useful for treating restenotic lesions |
| US12/217,028 US20090011005A1 (en) | 2006-01-13 | 2008-07-01 | Pharmaceuticals compositions containing nanomaterials useful for treating restenotic lesions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRC10600285-4A BRPI0600285C1 (pt) | 2006-01-13 | 2006-01-13 | compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0600285A true BRPI0600285A (pt) | 2007-10-02 |
| BRPI0600285C1 BRPI0600285C1 (pt) | 2011-10-11 |
Family
ID=38256650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRC10600285-4A BRPI0600285C1 (pt) | 2006-01-13 | 2006-01-13 | compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticas |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090011005A1 (pt) |
| EP (1) | EP1978957A4 (pt) |
| JP (1) | JP2009523133A (pt) |
| CN (1) | CN101365447A (pt) |
| AU (1) | AU2007204550A1 (pt) |
| BR (1) | BRPI0600285C1 (pt) |
| CA (1) | CA2636336A1 (pt) |
| WO (1) | WO2007079560A2 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
| US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US20080175887A1 (en) * | 2006-11-20 | 2008-07-24 | Lixiao Wang | Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs |
| US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
| EP2092942A1 (en) * | 2006-11-20 | 2009-08-26 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8414525B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
| US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
| US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
| WO2010024898A2 (en) | 2008-08-29 | 2010-03-04 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
| CA2798180A1 (en) | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| KR101314579B1 (ko) * | 2011-04-07 | 2013-10-10 | 광주과학기술원 | 파크리탁셀이 선적된 고분자 나노입자 및 그 제조방법 |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| HUP1400075A2 (hu) | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
| CN114028623B (zh) * | 2021-10-26 | 2024-02-27 | 江苏朴芃医疗科技有限公司 | 心脏分流器 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6537579B1 (en) * | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US6273913B1 (en) * | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
| US20030129215A1 (en) * | 1998-09-24 | 2003-07-10 | T-Ram, Inc. | Medical devices containing rapamycin analogs |
| TR200003435T2 (tr) * | 1998-05-20 | 2001-03-21 | The Liposome Company,Inc. | Yeni parçacıklı formülasyonlar |
| US8067032B2 (en) * | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| US20030065382A1 (en) * | 2001-10-02 | 2003-04-03 | Fischell Robert E. | Means and method for the treatment of coronary artery obstructions |
| US20050095267A1 (en) * | 2002-12-04 | 2005-05-05 | Todd Campbell | Nanoparticle-based controlled release polymer coatings for medical implants |
| CN102697737B (zh) * | 2003-04-03 | 2014-03-19 | 杰西.L.-S.奥 | 负载肿瘤靶向药物的颗粒 |
| MXPA05012467A (es) * | 2003-05-19 | 2006-02-22 | Baxter Int | Particulas solidas que comprenden un anticonvulsivo o un inmunosupresor revestido con uno o mas modificadores de superficie. |
| US8043631B2 (en) * | 2004-04-02 | 2011-10-25 | Au Jessie L S | Tumor targeting drug-loaded particles |
| JP2008512350A (ja) * | 2004-07-01 | 2008-04-24 | イェール ユニバーシティ | 標的化され、そして高密度で薬物が負荷されるポリマー性物質 |
| US7727554B2 (en) * | 2004-12-21 | 2010-06-01 | Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center | Sustained-release nanoparticle compositions and methods for using the same |
| WO2006102378A2 (en) * | 2005-03-21 | 2006-09-28 | Macusight, Inc. | Drug delivery systems for treatment of diseases or conditions |
-
2006
- 2006-01-13 BR BRC10600285-4A patent/BRPI0600285C1/pt active Search and Examination
-
2007
- 2007-01-12 EP EP07701600A patent/EP1978957A4/en not_active Withdrawn
- 2007-01-12 CA CA002636336A patent/CA2636336A1/en not_active Abandoned
- 2007-01-12 JP JP2008549721A patent/JP2009523133A/ja active Pending
- 2007-01-12 WO PCT/BR2007/000015 patent/WO2007079560A2/en not_active Ceased
- 2007-01-12 CN CNA2007800017443A patent/CN101365447A/zh active Pending
- 2007-01-12 AU AU2007204550A patent/AU2007204550A1/en not_active Abandoned
-
2008
- 2008-07-01 US US12/217,028 patent/US20090011005A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009523133A (ja) | 2009-06-18 |
| CN101365447A (zh) | 2009-02-11 |
| BRPI0600285C1 (pt) | 2011-10-11 |
| EP1978957A4 (en) | 2013-01-09 |
| WO2007079560A3 (en) | 2007-12-27 |
| AU2007204550A1 (en) | 2007-07-19 |
| US20090011005A1 (en) | 2009-01-08 |
| EP1978957A2 (en) | 2008-10-15 |
| WO2007079560A2 (en) | 2007-07-19 |
| CA2636336A1 (en) | 2007-07-19 |
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