BRPI0603073A - método para distribuição de fármacos para tecido sob propulsão de microjatos - Google Patents

método para distribuição de fármacos para tecido sob propulsão de microjatos

Info

Publication number
BRPI0603073A
BRPI0603073A BRPI0603073-4A BRPI0603073A BRPI0603073A BR PI0603073 A BRPI0603073 A BR PI0603073A BR PI0603073 A BRPI0603073 A BR PI0603073A BR PI0603073 A BRPI0603073 A BR PI0603073A
Authority
BR
Brazil
Prior art keywords
tissue
micro
drug
jet propelled
delivering drugs
Prior art date
Application number
BRPI0603073-4A
Other languages
English (en)
Inventor
Scott J Gilbert
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38357882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0603073(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of BRPI0603073A publication Critical patent/BRPI0603073A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587—Lighting arrangements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/59—Aesthetic features, e.g. distraction means to prevent fears of child patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)

Abstract

"MéTODO PARA DISTRIBUIçãO DE FáRMACOS PARA TECIDO SOB PROPULSãO DE MICROJATOS". A presente invenção refere-se a um método de distribuição de um fármaco para o tecido inclui as etapas de: fornecer um dispositivo de distribuição de fármaco possuindo pelo menos um bocal e um fármaco contido em uma parte do dispositivo; identificar um local para distribuição do fármaco em ou no tecido; colocar uma parte do dispositivo em ou perto do local; e distribuir o fármaco para o tecido no local através de pelo menos um bocal do dispositivo sob propulsão por microjatos.
BRPI0603073-4A 2005-08-10 2006-08-09 método para distribuição de fármacos para tecido sob propulsão de microjatos BRPI0603073A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/200,772 US20070055199A1 (en) 2005-08-10 2005-08-10 Drug delivery device for buccal and aural applications and other areas of the body difficult to access
US11/200,971 US8591457B2 (en) 2005-08-10 2005-08-10 Method for making a needle-free jet injection drug delivery device
US11/200,749 US8998881B2 (en) 2005-08-10 2005-08-10 Method for delivering drugs to tissue under microjet propulsion
US11/201,071 US20070055200A1 (en) 2005-08-10 2005-08-10 Needle-free jet injection drug delivery device

Publications (1)

Publication Number Publication Date
BRPI0603073A true BRPI0603073A (pt) 2007-03-27

Family

ID=38357882

Family Applications (3)

Application Number Title Priority Date Filing Date
BRPI0603087-4A BRPI0603087A (pt) 2005-08-10 2006-08-09 dispositivo de aplicação de fármacos de injeção de jato livre de agulha
BRPI0603073-4A BRPI0603073A (pt) 2005-08-10 2006-08-09 método para distribuição de fármacos para tecido sob propulsão de microjatos
BRPI0603196-0A BRPI0603196A (pt) 2005-08-10 2006-08-10 dispositivo para distribuição de fármacos para aplicações bucais e auriculares e outras áreas do corpo difìceis de acessar

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0603087-4A BRPI0603087A (pt) 2005-08-10 2006-08-09 dispositivo de aplicação de fármacos de injeção de jato livre de agulha

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0603196-0A BRPI0603196A (pt) 2005-08-10 2006-08-10 dispositivo para distribuição de fármacos para aplicações bucais e auriculares e outras áreas do corpo difìceis de acessar

Country Status (7)

Country Link
US (4) US20070055199A1 (pt)
EP (4) EP1752174B1 (pt)
JP (3) JP5095153B2 (pt)
CN (4) CN1911465B (pt)
AU (4) AU2006203195B2 (pt)
BR (3) BRPI0603087A (pt)
CA (4) CA2555400C (pt)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE409057T1 (de) 2002-02-11 2008-10-15 Antares Pharma Inc Intradermales injektionsgerät
US7638138B2 (en) * 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
WO2004087243A1 (ja) 2003-03-27 2004-10-14 Bioactis Limited 鼻腔用粉末薬剤施薬装置
WO2006016530A1 (ja) * 2004-08-10 2006-02-16 Translational Research, Ltd. 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
WO2006079064A1 (en) 2005-01-24 2006-07-27 Antares Pharma, Inc. Prefilled needle assisted jet injector
US7833189B2 (en) 2005-02-11 2010-11-16 Massachusetts Institute Of Technology Controlled needle-free transport
US20070055199A1 (en) * 2005-08-10 2007-03-08 Gilbert Scott J Drug delivery device for buccal and aural applications and other areas of the body difficult to access
WO2007058966A1 (en) * 2005-11-11 2007-05-24 Massachusetts Institute Of Technology Controlled needle-free eye injector
WO2007061896A1 (en) * 2005-11-17 2007-05-31 Zogenix, Inc. Delivery of viscous formulations by needle-free injection
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
CA2657435A1 (en) 2006-07-10 2008-07-03 Medipacs, Inc. Super elastic epoxy hydrogel
DE202006018609U1 (de) * 2006-08-29 2007-05-16 Euro-Celtique S.A. Verwendung von Opioidformulierungen in nadellosen Vorrichtungen zur Medikamentenverabreichung
US20090124996A1 (en) * 2006-11-03 2009-05-14 Scott Heneveld Apparatus and methods for injecting high viscosity dermal fillers
ES2652415T3 (es) 2006-12-26 2018-02-02 Shin Nippon Biomedical Laboratories, Ltd. Preparación para aplicación transnasal
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8827979B2 (en) 2007-03-19 2014-09-09 Insuline Medical Ltd. Drug delivery device
JP2008301847A (ja) * 2007-06-05 2008-12-18 Canon Inc 吸入装置及びその駆動方法
US9995295B2 (en) 2007-12-03 2018-06-12 Medipacs, Inc. Fluid metering device
US8409133B2 (en) 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
EP2231258A1 (en) 2007-12-21 2010-09-29 Aesthetic Sciences Corporation Self-contained pressurized injection device
US20100152646A1 (en) * 2008-02-29 2010-06-17 Reshma Girijavallabhan Intravitreal injection device and method
WO2009134336A1 (en) * 2008-04-28 2009-11-05 Zogenix, Inc. Novel formulations for treatment of migraine
EP2278947A4 (en) * 2008-05-21 2013-11-06 Teikoku Pharma Usa Inc TREATMENT OF DYSMENORRHEA BY TRANSDERMAL ADMINISTRATION OF NON-TEMPEROIDAL INFLAMMATORY DRUGS
US8398583B2 (en) 2008-07-09 2013-03-19 Massachusetts Institute Of Technology Method and apparatus for extraction of a sample from a sample source
US8231588B2 (en) * 2008-08-01 2012-07-31 Tian Xia Methods for ameliorating pain and devices for delivering a medicament
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
US7678078B1 (en) 2008-10-21 2010-03-16 KMG Pharma LLC Intravitreal injection device, system and method
EP2355758A2 (en) 2008-11-07 2011-08-17 Insuline Medical Ltd. Device and method for drug delivery
AU2010226442A1 (en) * 2009-03-20 2011-10-13 Antares Pharma, Inc. Hazardous agent injection system
EP2429495A4 (en) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd INTRANASAL PHARMACEUTICAL COMPOSITION WITH IMPROVED PHARMACOKINETICS
GB2472327B (en) * 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
US8758271B2 (en) 2009-09-01 2014-06-24 Massachusetts Institute Of Technology Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties
US9238102B2 (en) 2009-09-10 2016-01-19 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
EP2482915A4 (en) * 2009-10-02 2014-04-02 Insuline Medical Ltd DEVICE AND METHOD FOR DELIVERY OF MEDICATION TO TARGETED SKIN LAYER
US20110105990A1 (en) * 2009-11-04 2011-05-05 Silvestrini Thomas A Zonal drug delivery device and method
US20120003601A1 (en) 2009-12-15 2012-01-05 Massachusetts Institute Of Technology Jet Injector Use In Oral Evaluation
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
US8652118B2 (en) * 2010-04-08 2014-02-18 Kmg Pharma, Llc Sub-mucosal agent delivery, apparatus, system and method
US8430862B2 (en) * 2010-04-08 2013-04-30 KMG Pharma LLC Subconjunctival agent delivery apparatus, system and method
US8574217B2 (en) * 2010-04-08 2013-11-05 Kmg Pharma, Llc Sub-mucosal agent delivery method for the eye
CA2810078A1 (en) * 2010-09-15 2012-03-22 Zogenix, Inc. Needle-free injectors and design parameters thereof that optimize injection performance
CN107096101A (zh) * 2010-10-07 2017-08-29 麻省理工学院 使用伺服控制的无针注射器的注射方法
JP5934710B2 (ja) * 2010-10-07 2016-06-15 マサチューセッツ インスティテュート オブ テクノロジー ローレンツ力直動型の無針式ジェット注射システムを用いた固形物および／または流体の供給
US20130277443A1 (en) * 2010-10-20 2013-10-24 Wolfe Tory Medical, Inc. Miniature fluid atomizer
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
JP2013059424A (ja) * 2011-09-12 2013-04-04 Daicel Corp 無針注射器
JP6246995B2 (ja) * 2012-02-24 2017-12-13 株式会社ダイセル 無針注射器
JP2015510956A (ja) 2012-03-14 2015-04-13 メディパックス インコーポレイテッド 過剰反応性分子を含むスマートポリマー材料
EP2833944A4 (en) 2012-04-06 2016-05-25 Antares Pharma Inc ADMINISTRATION OF TESTOSTERONE COMPOSITIONS BY NEEDLE-SUPPORTED NOZZLE INJECTION
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
EP2854727B1 (en) 2012-05-24 2019-04-10 Altaviz LLC Viscous fluid injector
US9700375B2 (en) * 2012-06-30 2017-07-11 Rollins Enterprises, Llc Laser NIL liposuction system and method
CN102727980B (zh) * 2012-07-07 2013-12-11 安徽理工大学 用于局部麻醉的多喷口射流注射系统
KR101575039B1 (ko) * 2012-07-19 2015-12-07 (주)아모레퍼시픽 노즐 장치 및 이를 포함하는 최소 침습형 주입 장치
DE102012214152A1 (de) * 2012-08-09 2014-02-13 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zum gezielten Aufbringen eines Flüssigkeitsstrahls
EP2897535A4 (en) * 2012-09-24 2016-06-22 Cormatrix Cardiovascular Inc INJECTION DEVICE WITH MULTIPLE NEEDLES AND SYSTEM FOR THE DISTRIBUTION OF PHARMACOLOGICAL ACTIVE SUBSTANCES TO BIOLOGICAL TISSUE
PL2732770T3 (pl) * 2012-11-16 2016-12-30 Bezigłowe urządzenie do iniekcji
PT2953667T (pt) 2013-02-11 2020-01-28 Antares Pharma Inc Dispositivo de injeção a jato auxiliado por agulha tendo força de gatilho reduzida
JP6030803B2 (ja) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド ピニオンシステムを有する用量注射器
ES2689394T3 (es) * 2013-05-21 2018-11-13 Lts Lohmann Therapie-Systeme Ag Sistema de inyección para inyectar un gran volumen
US11278682B2 (en) 2014-11-09 2022-03-22 Sipnose Ltd. Device and method for aerosolized delivery of substance to a natural orifice of the body
US12329902B2 (en) 2013-08-22 2025-06-17 Sipnose Ltd. Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization
US11471618B2 (en) 2014-11-09 2022-10-18 Sipnose Ltd. Adjustable dosing delivery and multi sectioned drug compartment
US11992604B2 (en) 2014-11-09 2024-05-28 Sipnose Ltd. Devices and methods for delivering a substance to a body cavity
US11116914B2 (en) * 2014-11-09 2021-09-14 Sipnose Ltd. Device and method for aerosolized delivering of substance to a natural orifice of the body
US12491325B2 (en) 2013-08-22 2025-12-09 Aptargroup, Inc. Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity
DE202013105715U1 (de) 2013-08-22 2014-02-19 Sipnose Ltd. Vorrichtung zur Abgabe einer vorbestimmten Menge einer Substanz an eine natürliche Öffnung des Körpers
US12594388B2 (en) 2013-08-22 2026-04-07 Aptargroup, Inc. Device to deliver a predetermined amount of a substance to a natural orifice of the body
CN103463708A (zh) * 2013-08-29 2013-12-25 苏州大学 多点无针注射安瓿装置
AU2014312045B2 (en) 2013-08-30 2019-03-14 Hollister Incorporated Device for trans anal irrigation
BR112016009874B1 (pt) * 2013-11-05 2022-10-11 Synagile Corporation Dispositivos de liberação de fármaco, e composições farmacêuticas e usos
FR3014571B1 (fr) * 2013-12-11 2021-04-09 Dav Dispositif de commande a retour sensoriel
KR101606549B1 (ko) 2014-03-13 2016-03-25 주식회사 진성이앤지 마이크로제트 충돌을 이용한 나노입자 제조장치
US10213564B2 (en) * 2014-05-19 2019-02-26 Frank J. Cain Biomedical aural delivery systems and methods
JP6612017B2 (ja) * 2014-06-03 2019-11-27 株式会社ダイセル 無針注射器による注射システム
AU2015287992B2 (en) 2014-07-08 2020-03-12 Hollister Incorporated Trans anal irrigation platform with bed module
WO2016007533A1 (en) 2014-07-08 2016-01-14 Hollister Incorporated Portable trans anal irrigation device
US11191908B2 (en) * 2014-08-10 2021-12-07 Antares Pharma, Inc. Syringe shock absorber for use in an injection device
US9782549B2 (en) * 2014-10-22 2017-10-10 Ethicon, Inc. Distance indicators for medicinal spray devices
AU2016258179B2 (en) 2015-05-06 2021-07-01 Synagile Corporation Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use
JP6557409B2 (ja) 2015-06-03 2019-08-07 ノボピクシス・インコーポレイテッドＮｏｖｏｐｙｘｉｓ， Ｉｎｃ． 流体送達装置および方法
KR101667216B1 (ko) 2015-06-18 2016-10-18 방철환 약물 주입 장치
FR3038232B1 (fr) * 2015-06-30 2017-07-28 Crossject Dispositif d’injection sans aiguille equipe d’un ressort de compression
FR3038229B1 (fr) * 2015-06-30 2017-07-28 Crossject Dispositif d’injection sans aiguille equipe d’un dispositif de percussion perfectionne
KR102829941B1 (ko) 2015-11-13 2025-07-04 타르간 인크. 동물에 물질을 주입하기 위한 자동 시스템 및 방법
US10842467B2 (en) * 2015-12-15 2020-11-24 Portal Instruments, Inc. Biospecimen extraction apparatus
EP3398635B1 (en) * 2015-12-28 2021-12-08 Daicel Corporation Injection apparatus
CN105413024A (zh) * 2016-01-07 2016-03-23 深圳市赫拉铂氢时代科技有限公司 纳米/微米氢水无针注射仪及其注射方法
FR3047903B1 (fr) * 2016-02-18 2018-03-23 Crossject Dispositif d’injection sans aiguille a membrane cintree
US11020160B2 (en) * 2016-03-21 2021-06-01 Warsaw Orthopedic, Inc. Surgical injection system and method
EP3851135B1 (en) 2016-07-08 2025-11-26 Hollister Incorporated Body cavity irrigation system
JP6821779B2 (ja) 2016-07-08 2021-01-27 ホリスター・インコーポレイテッドＨｏｌｌｉｓｔｅｒ Ｉｎｃｏｒｐｏｒａｔｅｄ 経肛門的洗腸療法装置
EP3510161A4 (en) 2016-08-23 2020-04-22 Akouos, Inc. COMPOSITIONS AND METHODS FOR TREATING PERSONAL HEARING LOSS IN A PERSON
KR101757158B1 (ko) 2016-09-26 2017-07-26 방철환 약물 주입 장치
FR3057169B1 (fr) * 2016-10-11 2022-04-01 Crossject Buse d’injection pour dispositif d’injection sans aiguille
US11596422B2 (en) 2016-11-03 2023-03-07 Hollister Incorporated Adjustable bowel treatment arm
FR3058718B1 (fr) * 2016-11-15 2020-11-06 Crossject Procede de trempe a l’air d’un corps creux en verre allonge comprenant un percage axial
AU2017375606B2 (en) 2016-12-14 2021-12-23 Hollister Incorporated Transanal irrigation device and system
US20180256867A1 (en) * 2017-03-07 2018-09-13 Bruce H. Levin Nasal Delivery Device and Methods of Use
US10420679B2 (en) * 2017-04-21 2019-09-24 Victoria Fan Heated mist earache and infection treatment device
CN107316525A (zh) * 2017-05-24 2017-11-03 浙江中医药大学 一种医用教学模拟注射器
DE102017115779A1 (de) 2017-07-13 2019-01-17 Gerresheimer Regensburg Gmbh Spritzgusswerkzeug zum Herstellen eines Spritzgussteils und Verfahren zum Herstellen eines Spritzgussteils
KR101862201B1 (ko) * 2017-08-31 2018-05-29 제이에스케이바이오메드(주) 역류방지밸브가 구비된 마이크로젯 약물 주사 장치
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
WO2019156238A1 (ja) * 2018-02-09 2019-08-15 株式会社ダイセル 注入器及びそれを用いた注入対象への生体分子を含む溶液の注入方法
WO2019156239A1 (ja) * 2018-02-09 2019-08-15 株式会社ダイセル 注入器及びそれを用いた注入対象の細胞核内への生体分子を含む溶液の注入方法
JP7280201B2 (ja) * 2018-02-09 2023-05-23 株式会社ダイセル 注入器
FR3080843B1 (fr) * 2018-05-07 2020-05-29 Horus Pharma Dispositif de conditionnement et distribution d'un produit ayant un embout doseur a extremite exterieurement propre
JP2019005589A (ja) * 2018-07-19 2019-01-17 ウルフ トリー メディカル インコーポレイテッド 小型流体噴霧器
US11472131B2 (en) * 2018-08-06 2022-10-18 Portal Instruments, Inc. Injection nozzle and method of making same
US11638794B2 (en) 2018-10-23 2023-05-02 Aktivax, Inc. Intranasal pressure drug delivery device
WO2020106757A1 (en) * 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
CN109431679B (zh) * 2018-12-06 2024-02-06 苏州理想眼科医院有限公司 一种眼内精密器械无摩擦手柄
CN109701143B (zh) * 2018-12-26 2021-03-19 孟荣华 一种便携式鼻腔上药器
FR3092254B1 (fr) * 2019-02-01 2021-10-29 Crossject Dispositif de contrôle de pression ou alternativement de force d’injection d’une pluralité de jets générés en sortie d’un dispositif d'injection sans aiguille
CN113692274A (zh) 2019-03-01 2021-11-23 拉尼医疗有限公司 从可吞咽装置到患者的肠道中的推进药物递送
KR102274614B1 (ko) * 2019-08-26 2021-07-07 제이에스케이바이오메드(주) 멀티노즐이 구비된 바늘 없는 주사기 및 이의 제조방법
CN110860030B (zh) * 2019-11-19 2021-10-15 深圳市佳鑫一帆科技有限公司 一种无针水光针的制造方法
JP7447446B2 (ja) * 2019-11-28 2024-03-12 セイコーエプソン株式会社 薬液投与方法
CN116096905A (zh) 2020-02-21 2023-05-09 阿库斯股份有限公司 用于治疗人受试者的非年龄相关性听力损伤的组合物和方法
US11666741B1 (en) * 2021-06-01 2023-06-06 TruCelium Inc. Method for delivering matter into the human body
CN113318301A (zh) * 2021-06-28 2021-08-31 北京科技大学 一种大剂量多孔无针注射器
CN114984379B (zh) * 2022-05-18 2024-02-09 浙江工业大学 高压驱动无针注射装置
WO2025003228A1 (en) * 2023-06-27 2025-01-02 Intervet International B.V. Injection system
JPWO2025009547A1 (pt) * 2023-07-05 2025-01-09
CN117504053B (zh) * 2023-11-16 2024-11-29 江苏乐聚医药科技有限公司 用于无针注射器的药管和包括该药管的无针注射器
WO2025206737A1 (ko) * 2024-03-26 2025-10-02 바즈바이오메딕 주식회사 무바늘 주사기
CN121059946A (zh) * 2025-10-30 2025-12-05 北京理工大学 一种超高速射流深度可控的药物递送设备

Family Cites Families (316)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE902776C (de) 1949-08-17 1954-01-28 August Rooseboom Selbsttaetiger Injektionsapparat mit Ampulle
US2687730A (en) 1951-12-04 1954-08-31 Jr George N Hein Ampoule
US3055362A (en) 1956-05-16 1962-09-25 Auguste Rooseboom Hypodermic injection apparatus
US3306291A (en) * 1964-04-14 1967-02-28 Burron Medical Prod Inc Disposable sterile syringes, needle containers and the like having prestressed frangible portions therein
US3403679A (en) 1964-12-11 1968-10-01 Secr Defence Brit Hypodermic injection apparatus with a secondary capsule-collapsing means
FR2052106A6 (pt) 1969-07-16 1971-04-09 Merieux Inst
US3688765A (en) 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
BE795162A (fr) * 1972-02-10 1973-08-08 Philips Nv Injektie-inrichting
US3802430A (en) * 1972-06-30 1974-04-09 L Arnold Disposable pyrotechnically powered injector
US4137804A (en) * 1974-07-12 1979-02-06 Gerber Garment Technology, Inc. Fluid cutting jet receiver
US3945379A (en) * 1974-08-08 1976-03-23 Smithkline Corporation Injection device
US3933155A (en) * 1975-01-23 1976-01-20 Mizzy Inc. Pressure injector apparatus having improved trigger mechanism
US4031889A (en) 1975-03-25 1977-06-28 William Floyd Pike Power operated aspirating hypodermic syringe
US4165739A (en) 1976-09-02 1979-08-28 Doherty Norman R Inoculator
US4165800A (en) 1976-09-02 1979-08-28 Doherty Norman R Device for spring-loading a needleless innoculator
US4089334A (en) * 1976-10-07 1978-05-16 Schwebel Paul R Pyrotechnically powered needleless injector
US4104105A (en) 1976-10-28 1978-08-01 Burroughs Corporation Automatic overlay attaching apparatus
USD248568S (en) * 1976-12-13 1978-07-18 Aaron Ismach Animal intradermal nozzle for jet injection device
US4108176A (en) 1977-02-25 1978-08-22 Agri-Bio Corporation Automatic injecting apparatus
US4188949A (en) * 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
US4152060A (en) 1977-08-10 1979-05-01 Polaroid Corporation Epicyclic electromechanically actuated lens drive
DE2832252A1 (de) 1978-07-22 1980-01-31 Hoechst Ag Impfpistole
BR7806153A (pt) * 1978-09-19 1980-04-01 Halen Elliot Brasil Ind Com Eq Injetor hipodermico a pressao para vacinacao intermitente
DE2947376A1 (de) 1979-11-24 1981-06-11 Wolfgang Dipl.-Chem. Dr. Bobo-Dioulasso Hirsch Verfahren zur herstellung von trifluoressigsaeurederivaten
US4342310A (en) 1980-07-08 1982-08-03 Istvan Lindmayer Hydro-pneumatic jet injector
US4403609A (en) 1981-02-24 1983-09-13 Cohen Edgar C Vacuum-compression injector
US4421508A (en) 1981-02-24 1983-12-20 Cohen Edgar C Vacuum-compression injector
DE3115377A1 (de) 1981-04-16 1982-12-16 Hoechst Ag, 6000 Frankfurt Nadelloses injektionsgeraet
DE3115374A1 (de) 1981-04-16 1982-11-11 Hoechst Ag, 6000 Frankfurt Nadelloses injektionsgeraet
DE3115373A1 (de) 1981-04-16 1982-11-11 Hoechst Ag, 6000 Frankfurt Nadelloses injektionsgeraet
DE3115376A1 (de) 1981-04-16 1982-12-16 Hoechst Ag, 6000 Frankfurt Nadelloses injektionsgeraet
US4447225A (en) * 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
CA1178503A (en) 1982-05-27 1984-11-27 Health-Mor Personal Care Corporation Needleless hypodermic injector
HU189198B (en) 1982-12-10 1986-06-30 Adorjan,Andras,Hu Plastic syringe for single use as well as plastic piston particularly for plastic syringes
IT1195615B (it) 1983-01-24 1988-10-19 Mario Geat Dispositivo iniettore ttancutaneo
DK149527C (da) * 1983-03-23 1987-06-22 Kr Ger Maskinfabrik A S M Fugepistol
US4518385A (en) * 1983-06-13 1985-05-21 Preci-Tech Ltd. Disposable syringe for needleless injector
US4518384A (en) 1983-06-17 1985-05-21 Survival Technology, Inc. Multiple medicament cartridge clip and medicament discharging device therefor
HU186718B (en) 1983-06-29 1985-09-30 Radelkis Electrokemiai Automatic needleless syringe operable by cardox cylinder suitable for personal giving injection e.g. insulin
HU194056B (en) 1983-11-14 1988-01-28 Tibor Pelvay Semi-automatic injecting instrument
DE3427187A1 (de) * 1984-07-24 1986-01-30 Hoechst Ag, 6230 Frankfurt Nadelloses injektionsgeraet
US4678461A (en) 1984-11-01 1987-07-07 Survival Technology, Inc. Automatic injector with improved glass container protector
US4596556A (en) * 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
CN85200273U (zh) * 1985-04-01 1985-09-10 大连化学工业公司 无针注射器
US4592752A (en) 1985-08-02 1986-06-03 Neefe Charles W Non-optical corneal drug delivery
ATE95998T1 (de) 1985-09-27 1993-11-15 Mentor O & O Inc Unabhaengiges, tragbares ultraschall-instrument zur anwendung in der augenheilkunde.
US4680027A (en) * 1985-12-12 1987-07-14 Injet Medical Products, Inc. Needleless hypodermic injection device
JPH0649038B2 (ja) 1986-04-14 1994-06-29 財団法人ライフテクノロジー研究所 医療用カプセル
EP0250022A3 (en) * 1986-06-17 1988-06-22 SICIM SpA Portable endermic injector
HU197218B (en) 1986-07-30 1989-03-28 Robert Mate Self-injecting device for throw -away medical syringe provided with feeder
EP0261719A3 (en) 1986-09-23 1990-10-10 Akzo N.V. Thermochemiluminescent cyclodextrin complexes
US4722728A (en) * 1987-01-23 1988-02-02 Patents Unlimited, Ltd. Needleless hypodermic injector
HU195428B (en) 1987-02-17 1988-05-30 Fegyver Es Gazkeszuelekgyar Needleless vaccinating instrument of adjustable injection depth operable by hand-power
DE3715258C2 (de) * 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injektionsgerät
JPH0622637B2 (ja) 1987-05-26 1994-03-30 アカリス，クロード 特に歯科治療用の針の無い液体注射装置
US5569190A (en) 1987-06-08 1996-10-29 D'antonio; Nicholas F. Hypodermic fluid dispenser
US6056716A (en) 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
US4940460A (en) * 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) * 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US5009637A (en) * 1987-11-16 1991-04-23 Sy-Quest International Limited Apparatus for hypodermic injection of liquids
US4874367A (en) 1988-02-05 1989-10-17 Marpam International, Inc. Hypodermic jet injector and cartridge therefor
US5073165A (en) 1988-02-05 1991-12-17 Marpam International, Inc. Hypodermic jet injector and cartridge therefor
US5179022A (en) * 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
US5195526A (en) * 1988-03-11 1993-03-23 Michelson Gary K Spinal marker needle
US4913699A (en) * 1988-03-14 1990-04-03 Parsons James S Disposable needleless injection system
GB8809115D0 (en) * 1988-04-18 1988-05-18 Turner R C Syringes
US4894054A (en) 1988-06-20 1990-01-16 Miskinyar Shir A Preloaded automatic disposable syringe
US5066276A (en) 1988-06-21 1991-11-19 Alcon Laboratories, Inc. Method and apparatus for injecting viscous fluid into the eye to lift pre-retinal and post-retinal membrane with linear pressure control
JPH0720857B2 (ja) 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
USRE35986E (en) 1988-08-23 1998-12-08 Meridian Medical Technologies, Inc. Multiple chamber automatic injector
US5024656A (en) * 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US6132763A (en) 1988-10-20 2000-10-17 Polymasc Pharmaceuticals Plc Liposomes
US5151098A (en) * 1990-07-23 1992-09-29 Hanspeter Loertscher Apparatus for controlled tissue ablation
US4944726A (en) * 1988-11-03 1990-07-31 Applied Vascular Devices Device for power injection of fluids
FR2638360A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Injecteur d'insuline automatique sans aiguille, portable avec plusieurs tetes d'injection interchangeables a multitrous
DE3901691A1 (de) * 1988-11-21 1990-07-26 Holzer Walter Verfahren und hilfsmittel zur nadellosen injektion
US4894405A (en) * 1988-11-25 1990-01-16 Tremco Incorporated Concrete and masonry waterproofing composition
WO1990010771A1 (en) 1989-03-15 1990-09-20 Mitsubishi Metal Corporation Crack repairing method
IE72466B1 (en) 1989-03-17 1997-04-09 Baxter Int Blunt-ended cannula device
US5057087A (en) * 1989-04-24 1991-10-15 Harmon James E Hypodermic needle safety system
US5102393A (en) 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US5056973A (en) 1989-10-16 1991-10-15 Textron Inc. Bulb fastener
US5620689A (en) * 1989-10-20 1997-04-15 Sequus Pharmaceuuticals, Inc. Liposomes for treatment of B-cell and T-cell disorders
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
GB8926825D0 (en) 1989-11-28 1990-01-17 Glaxo Group Ltd Device
DE4010355A1 (de) * 1990-03-28 1991-10-02 Schering Ag Bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
US5062830A (en) 1990-04-04 1991-11-05 Derata Corporation Dry disposable nozzle assembly for medical jet injector
US5092843A (en) * 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
US5531707A (en) * 1990-06-08 1996-07-02 Ab Astra Device for introducing a substance into a body cavity of a patient
US5273530A (en) * 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5352196A (en) 1990-11-19 1994-10-04 Habley Medical Technology Corporation Mixing vial
US5275918A (en) * 1991-02-27 1994-01-04 E. I. Du Pont De Nemours And Company Ultraviolet curable heat activatable transfer toners
US5176645A (en) 1991-05-01 1993-01-05 Diana Corporation Pneumatic, modular device for dispensing medication to animals
GB9111600D0 (en) 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
IT1252832B (it) 1991-08-06 1995-06-28 Sicim Spa Testina monouso per iniettori per iniezioni sottocutanee senza ago
US5190523A (en) * 1991-08-16 1993-03-02 Idee International R & D Inc. Disposable syringe and injector
GB9118204D0 (en) * 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
GB9125699D0 (en) 1991-12-03 1992-01-29 Glaxo Group Ltd Device
GB9126209D0 (en) 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
FR2690838B1 (fr) 1992-05-06 1996-07-12 Rhone Merieux Ensemble de vaccination contre la maladie hemorragique virale du lapin et vaccins conditionnes pour etre utilises dans cet ensemble.
WO1993023552A1 (en) * 1992-05-21 1993-11-25 Government Of The United States As Represented By Secretary Department Of Health And Human Services Targeting gene expression to living tissue using jet injection
US5236424A (en) 1992-06-05 1993-08-17 Cardiac Pathways Corporation Catheter with retractable cannula for delivering a plurality of chemicals
AU4058993A (en) 1992-06-15 1994-01-04 Max Wyssmann Device for the intentional and controllable distribution of a liquid or visquous material
US5383851A (en) * 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5304128A (en) * 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
WO1994007554A1 (en) * 1992-09-28 1994-04-14 Equidyne Systems, Incorporated Hypodermic jet injector
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
IT1256577B (it) 1992-12-11 1995-12-11 Ermanno Greco Dispositivo predisposto per la somministrazione automatica di un farmaco per via intradermica.
US5395619A (en) 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
US6326353B1 (en) 1993-03-23 2001-12-04 Sequus Pharmaceuticals, Inc. Enhanced circulation effector composition and method
US6180134B1 (en) * 1993-03-23 2001-01-30 Sequus Pharmaceuticals, Inc. Enhanced ciruclation effector composition and method
US5746714A (en) 1993-04-05 1998-05-05 P.A.T.H. Air powered needleless hypodermic injector
TW360548B (en) * 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
GB9307624D0 (en) 1993-04-13 1993-06-02 Smith & Nephew Wound dressing
US5951531A (en) 1993-04-20 1999-09-14 Medchem Products, Inc. Apparatus and method for applying a particulate hemostatic agent to living tissue
EP0695169B1 (en) 1993-04-22 2002-11-20 SkyePharma Inc. Multivesicular cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use
US5695472A (en) 1993-05-27 1997-12-09 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5358489A (en) 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5453096A (en) 1993-07-26 1995-09-26 Merck & Co., Inc. Device for the distribution of successive doses of a fluid product-in particular medicinal or cosmetic-contained in a vial
JP3487856B2 (ja) * 1993-07-31 2004-01-19 ウェストン メディカル リミテッド 無針注射器
US5425715A (en) 1993-08-05 1995-06-20 Survival Technology, Inc. Reloadable injector
US5464629A (en) 1993-11-16 1995-11-07 Georgetown University Method of forming hydrogel particles having a controlled size using liposomes
US5330430A (en) 1993-12-06 1994-07-19 Sullivan Robert J Retractable syringe applicator
US5354286A (en) 1993-12-07 1994-10-11 Survival Technology, Inc. Injection device having polyparaxylylene coated container
HU214350B (hu) 1993-12-13 1998-03-30 Mom Invest Kft. Tűnélküli oltókészülék
FR2715071B1 (fr) 1994-01-17 1996-03-01 Aguettant Lab Injecteur automatique de médicament.
EP1293559B1 (en) * 1994-01-21 2005-07-27 Powderject Vaccines, Inc. Gas driven gene delivery instrument
FR2718357B1 (fr) 1994-04-06 1997-10-03 Defarges Alain Moreau Perfectionnements apportés à un dispositif d'injection par jet sans aiguille.
US5899880A (en) * 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
GB9408500D0 (en) 1994-04-28 1994-06-22 Pa Consulting Services Improvements in or relating to injection devices
GB9411115D0 (en) * 1994-06-03 1994-07-27 Secr Defence Stabilisation of photosensitive material
GB9412301D0 (en) 1994-06-17 1994-08-10 Safe T Ltd Hollow-needle drugs etc applicators
US5540657A (en) * 1994-07-15 1996-07-30 Collagen Corporation Delivery device for injectable materials
US5604680A (en) * 1994-08-15 1997-02-18 Cadence Design Systems, Inc. Virtual interface representation of hierarchical symbolic layouts
US5837276A (en) 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5591184A (en) * 1994-10-13 1997-01-07 Sentinel Medical, Inc. Fluid jet surgical cutting instrument
US5876380A (en) * 1994-10-19 1999-03-02 Manganini; Steven J. Portable syringe dispenser system
AUPM922394A0 (en) 1994-11-03 1994-11-24 Astra Pharmaceuticals Pty Ltd Plastic syringe with overcap
US6214388B1 (en) * 1994-11-09 2001-04-10 The Regents Of The University Of California Immunoliposomes that optimize internalization into target cells
GB9426379D0 (en) * 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
GB9502879D0 (en) * 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
US5792099A (en) 1995-02-14 1998-08-11 Decamp; Dennis Syringe and cannula for insertion of viscoelastic material into an eye and method of using same
GB9504878D0 (en) 1995-03-10 1995-04-26 Weston Medical Ltd Viscously coupled actuator
US5503628A (en) 1995-03-15 1996-04-02 Jettek, Inc. Patient-fillable hypodermic jet injector
DE29507987U1 (de) 1995-05-15 1996-09-19 Ferton Holding, Delemont Ejektionsgerät zur Hochdruckejektion einer Flüssigkeit
US5501666A (en) * 1995-05-24 1996-03-26 Mycone Dental Supply Co. Needleless injector
US5730723A (en) * 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
GB9515846D0 (en) 1995-08-02 1995-10-04 Boc Group Plc Gas capsule
CN1147107A (zh) 1995-09-14 1997-04-09 王文华 一种汉字编码方法及其键盘
FR2739562B1 (fr) * 1995-10-09 1998-04-24 Moreau Defarges Alain Dispositif d'injection par jet sans aiguille, comportant une cartouche surmoulee
US6080130A (en) * 1998-11-14 2000-06-27 Castellano; Thomas P. Gas power source for a needle-less injector
US6013050A (en) * 1995-10-20 2000-01-11 Powderject Research Limited Particle delivery
US5567160A (en) 1995-10-26 1996-10-22 Survival Technology, Inc. Autoinjector training device
US5840062A (en) 1995-11-08 1998-11-24 Gumaste; Anand V. Solid state fluid delivery system
US5899879A (en) 1995-12-19 1999-05-04 Genesis Medical Technologies, Inc. Spring-actuated needleless injector
US5836911A (en) 1996-02-01 1998-11-17 Medi-Ject Corporation Injection device having positioning means
US5921967A (en) * 1996-02-29 1999-07-13 Medi-Ject Corporation Plunger for nozzle assembly
US5697917A (en) 1996-02-29 1997-12-16 Medi-Ject Corporation Nozzle assembly with adjustable plunger travel gap
US5800388A (en) 1996-02-29 1998-09-01 Medi-Ject Corporation Plunger/ram assembly adapted for a fluid injector
US5722953A (en) * 1996-02-29 1998-03-03 Medi-Ject Corporation Nozzle assembly for injection device
EP0956059A1 (en) * 1996-02-29 1999-11-17 Medi-Ject Corporation Nozzle assembly with adjustable plunger travel gap
TW341721B (en) 1996-03-14 1998-10-01 Matsushita Electric Industrial Co Ltd Formation of flat pattern, flat pattern forming apparatus, and semiconductor integrated circuit device
US5782802A (en) 1996-03-22 1998-07-21 Vitajet Corporation Multiple use needle-less hypodermic injection device for individual users
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
US6405936B1 (en) * 1996-05-13 2002-06-18 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
CZ294265B6 (cs) 1996-07-01 2004-11-10 Pharmacia & Upjohn Ab Injekční zařízení a způsob ovládání jeho pracovní činnosti
FR2751228B1 (fr) 1996-07-19 1998-11-20 Rhone Merieux Vaccin polynucleotidique bovin pour voie intradermique
CA2209406C (en) * 1996-07-24 2007-05-15 David W. Birch Gas capsule and gas delivery system
NL1004059C2 (nl) * 1996-09-18 1998-03-19 Plastic Moulding Appliances B Samenstel van houder en breeksluiting en werkwijze voor de vervaardiging daarvan.
BR9711420A (pt) 1996-09-26 1999-08-24 Akzo Nobel Nv Injetor sem agulha
US6009504A (en) 1996-09-27 1999-12-28 Intel Corporation Apparatus and method for storing data associated with multiple addresses in a storage element using a base address and a mask
ES2251728T3 (es) * 1996-10-09 2006-05-01 Hns International Inc. Injex-Equidyne Systems Inyector hipodermico a chorro.
AU4907897A (en) * 1996-10-11 1998-05-11 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method
US6224903B1 (en) 1996-10-11 2001-05-01 Sequus Pharmaceuticals, Inc. Polymer-lipid conjugate for fusion of target membranes
US6056973A (en) 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
EP0957980A4 (en) * 1996-11-27 2000-03-29 Gen Hospital Corp DELIVERY OF CONNECTIONS BY TRANSIENT IMPULSES
DE29724735U1 (de) * 1996-12-11 2003-11-13 GeSIM Gesellschaft für Silizium-Mikrosysteme mbH, 01454 Großerkmannsdorf Mikroejektionspumpe
DE19701494A1 (de) 1997-01-17 1998-07-23 Boehringer Mannheim Gmbh Transdermales Injektionssystem
US5860957A (en) 1997-02-07 1999-01-19 Sarcos, Inc. Multipathway electronically-controlled drug delivery system
US6179583B1 (en) * 1997-02-25 2001-01-30 Weston Medical Limited Metered fluid delivery device
US5888615A (en) * 1997-03-04 1999-03-30 Avery Dennison Corporation Cling films and articles
US5926723A (en) 1997-03-04 1999-07-20 Advanced Micro Devices, Inc. Generation of a loose planarization mask having relaxed boundary conditions for use in shallow trench isolation processes
US5938637A (en) 1997-03-14 1999-08-17 Path Single-use medicine delivery unit for needleless hypodermic injector
DE19712064A1 (de) 1997-03-24 1998-10-01 Braunewell Markus Elektromagnetischer Antrieb
WO1998042959A1 (de) 1997-03-24 1998-10-01 Lsp Innovative Automotive Systems Gmbh Elektromagnetische stellvorrichtung
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
US5911703A (en) 1997-05-22 1999-06-15 Avant Drug Delivery Systems, Inc. Two-stage fluid medicament jet injector
EP0888790A1 (en) 1997-07-04 1999-01-07 PowderJect Research Limited Drug particle delivery device
WO1999003521A1 (en) * 1997-07-14 1999-01-28 Novo Nordisk A/S Injection member
US6074360A (en) * 1997-07-21 2000-06-13 Boehringer Mannheim Gmbh Electromagnetic transdermal injection device and methods related thereto
GB9716065D0 (en) * 1997-07-31 1997-10-01 Owen Mumford Ltd Improvements relating to injection devices
US6171276B1 (en) 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
US5921966A (en) 1997-08-11 1999-07-13 Becton Dickinson And Company Medication delivery pen having an improved clutch assembly
US6149626A (en) 1997-10-03 2000-11-21 Bachynsky; Nicholas Automatic injecting syringe apparatus
IE970782A1 (en) 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
CA2301534A1 (en) 1997-10-23 1999-05-06 Morten Mernoe An infusion pump system and an infusion pump unit
US6610042B2 (en) 1997-12-05 2003-08-26 Felton Medical, Inc. Disposable unit-dose jet-injection syringe for pre-filled and/or transfilled liquid injectable medical drug or vaccine products and method thereof
ATE269669T1 (de) 1998-01-12 2004-07-15 Alsensa Aps Injektionseinheit
GB9808408D0 (en) 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
US6156008A (en) 1998-05-04 2000-12-05 Castellano; Thomas P. Device for avoiding subdermal hematomas from an injection
US6063054A (en) * 1998-05-13 2000-05-16 Mark L. Anderson Injector pump
US6063132A (en) 1998-06-26 2000-05-16 International Business Machines Corporation Method for verifying design rule checking software
US6189136B1 (en) * 1998-07-20 2001-02-13 Philips Electronics, North America Corp. Design level optical proximity correction methods
CN1651103A (zh) 1998-07-27 2005-08-10 安塔雷斯药品公司 一种注射装置
US6428528B2 (en) * 1998-08-11 2002-08-06 Antares Pharma, Inc. Needle assisted jet injector
GB9818110D0 (en) 1998-08-19 1998-10-14 Weston Medical Ltd Needleless injectors and other devices
JP2000074226A (ja) 1998-08-27 2000-03-14 Eagle Ind Co Ltd メカニカルシール
GB9819962D0 (en) * 1998-09-15 1998-11-04 Weston Medical Ltd Needleless injection cartridge
US6506177B2 (en) * 1998-10-14 2003-01-14 Sergio Landau Needle-less injection system
SE9803662D0 (sv) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab Autoinjector
EP1131124B1 (fr) * 1998-11-17 2006-01-18 Henri Mehier Dispositif destine a assurer la delivrance d'une substance active directement au sein d'un tissu cellulaire, moyen d'implantation du dispositif et appareils destines a l'injection de substance active dans ledit dispositif
US6096002A (en) 1998-11-18 2000-08-01 Bioject, Inc. NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method
US6689093B2 (en) * 1998-11-18 2004-02-10 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6783509B1 (en) 1998-11-18 2004-08-31 Bioject Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6264629B1 (en) 1998-11-18 2001-07-24 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6304673B1 (en) 1998-12-04 2001-10-16 Shou-Min Tseng Method and device for automatic matching of seal prints
US6232113B1 (en) * 1998-12-08 2001-05-15 Tien-Li Lee Particle bombardment device
US6383168B1 (en) 1998-12-08 2002-05-07 Bioject Medical Technologies Inc. Needleless syringe with prefilled cartridge
US6132395A (en) 1998-12-08 2000-10-17 Bioject, Inc. Needleless syringe with prefilled cartridge
ATE307627T1 (de) 1998-12-18 2005-11-15 Biovalve Technologies Inc Injektionsvorrichtung
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
DE19859133C1 (de) 1998-12-21 2000-05-18 Ferton Holding Sa Ejektionsgerät zur Hochdruckejektion einer Flüssigkeit
DE19859137C1 (de) * 1998-12-21 2000-05-18 Ferton Holding Sa Ejektionsgerät zur Hochdruckejektion einer Flüssigkeit
SE525728C2 (sv) * 1999-01-27 2005-04-12 Ericsson Telefon Ab L M Portabel telekommunikationsanordning för flera ljudtillbehör
US6849060B1 (en) * 1999-01-29 2005-02-01 Powderject Research Limited Particle delivery device
US6375638B2 (en) * 1999-02-12 2002-04-23 Medtronic Minimed, Inc. Incremental motion pump mechanisms powered by shape memory alloy wire or the like
US6258062B1 (en) 1999-02-25 2001-07-10 Joseph M. Thielen Enclosed container power supply for a needleless injector
EP1033143B1 (en) 1999-02-26 2007-01-10 F. Hoffmann-La Roche Ag Device for administering a medication
DE19913344C1 (de) 1999-03-24 2000-08-24 Deutscher Zahnarzt Verlag Dzv Nadelloses Injektionsgerät
AU4656000A (en) * 1999-04-22 2000-11-10 Gilbert Garitano Needleless permanent makeup and tattoo device
EP1180046A2 (en) 1999-05-19 2002-02-20 Weston Medical Limited Needleless injector drug capsule
AU5595300A (en) 1999-06-02 2000-12-18 Microheart, Inc. Devices and methods for delivering a drug
KR100758158B1 (ko) 1999-07-14 2007-09-12 알자 코포레이션 중성 지질중합체 및 그를 함유하는 리포솜 조성물
FR2796288B1 (fr) 1999-07-16 2001-08-10 Cross Site Technologies Seringue sans aiguille avec injecteur a elements emboites
FR2796289B1 (fr) 1999-07-16 2001-08-10 Cross Site Technologies Seringue sans aiguille avec injecteur a elements superposes
PT1649886E (pt) 1999-07-23 2008-05-28 Mannkind Corp Cápsulas de dose unitária para um inalador de pó seco
US6319224B1 (en) 1999-08-20 2001-11-20 Bioject Medical Technologies Inc. Intradermal injection system for injecting DNA-based injectables into humans
US6656164B1 (en) 1999-09-07 2003-12-02 Computer Controlled Syringe, Inc. Retractable needle device
US6224567B1 (en) * 1999-09-08 2001-05-01 Cambridge Biostability Limited Modified disposable injector device
EP1220697B1 (en) 1999-10-11 2004-12-29 Felton International, Inc. Universal anti-infectious protector for needleless injectors
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6673035B1 (en) * 1999-10-22 2004-01-06 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US6344027B1 (en) * 1999-12-08 2002-02-05 Scimed Life Systems, Inc. Needle-less injection apparatus and method
FR2802103B1 (fr) 1999-12-08 2003-10-03 Poudres & Explosifs Ste Nale Seringue sans aiguille fonctionnant avec entrainement du principe actif par effet tube a choc
FR2802102B1 (fr) * 1999-12-08 2002-07-12 Poudres & Explosifs Ste Nale Seringue sans aiguille munie d'un tube d'ejection a section constante
EP1242132B1 (en) * 1999-12-23 2003-10-15 Arnold Neracher Injection device and propulsion system therefor
FR2802820B1 (fr) * 1999-12-27 2002-10-18 Poudres & Explosifs Ste Nale Seringue sans aiguille fonctionnant par effet tube a choc, avec maintien prealable du principe actif sur le cote
WO2001051109A1 (en) 2000-01-07 2001-07-19 Biovalve Technologies, Inc. Injection device
US6210359B1 (en) * 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
FR2804329B1 (fr) 2000-02-02 2002-12-13 Poudres & Explosifs Ste Nale Seringue sans aiguille munie d'un opercule contenant le principe actif
FR2804869B1 (fr) 2000-02-11 2002-05-17 Poudres & Explosifs Ste Nale Seringue sans aiguille pour l'injection d'un liquide contenu dans une ampoule pre-remplie
CA2331030A1 (en) 2000-02-16 2001-08-16 Roche Diagnostics Gmbh Hypodermic needleless injection system
FR2805749B1 (fr) 2000-03-01 2002-05-17 Poudres & Explosifs Ste Nale Seringue sans aiguille a deux niveaux de vitesse d'injection
DE10010123A1 (de) * 2000-03-03 2001-09-20 Boehringer Ingelheim Int Nadelloser Injektor in Miniaturausführung
US6689092B2 (en) * 2000-03-03 2004-02-10 Boehringer International Gmbh Needle-less injector of miniature type
WO2001070309A1 (en) * 2000-03-23 2001-09-27 Antares Pharma, Inc. Single use disposable jet injector
US6558348B2 (en) 2000-04-07 2003-05-06 Equidyne Systems, Inc. Low cost disposable needleless injector system for variable and fixed dose applications
FR2807946B1 (fr) 2000-04-19 2002-06-07 Poudres & Explosifs Ste Nale Seringue sans aiguille fonctionnant avec un chargement pyrotechnique bicomposition
US6716190B1 (en) * 2000-04-19 2004-04-06 Scimed Life Systems, Inc. Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body
US6689101B2 (en) * 2000-05-22 2004-02-10 Pharmacia Ab Medical arrangement
US6740062B2 (en) * 2000-05-22 2004-05-25 Pharmacia Ab Medical device
US6406456B1 (en) 2000-06-08 2002-06-18 Avant Drug Delivery Systems, Inc. Jet injector
US6645169B1 (en) 2000-06-08 2003-11-11 Avant Drug Delivery Systems, Inc. Air-in-tip jet injector
WO2001097900A1 (en) * 2000-06-21 2001-12-27 Medjet Inc. Method and process for generating a high repetition rate pulsed microjet
US6733929B2 (en) 2000-07-05 2004-05-11 Numerical Technologies, Inc. Phase shift masking for complex patterns with proximity adjustments
EP1172721A1 (en) * 2000-07-10 2002-01-16 Sony International (Europe) GmbH Method for controlling network devices via a MMI
US6418551B1 (en) 2000-08-03 2002-07-09 Avant! Corporation Design rule checking tools and methods that use waiver layout patterns to waive unwanted dimensional check violations
US6602222B1 (en) 2000-10-13 2003-08-05 Cambridge Biostability Ltd. Disposable injection device
FR2815544B1 (fr) 2000-10-23 2003-02-14 Poudres & Explosifs Ste Nale Seringue sans aiguille securisee a architecture compacte
US6652483B2 (en) 2000-11-07 2003-11-25 Avant Drug Delivery Systems, Inc. Needleless jet injector system with separate drug reservoir
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
SE0100091D0 (sv) 2001-01-12 2001-01-12 Pharmacia Ab A device and a method for dispensing at least two mutually reactive components
AUPR272901A0 (en) * 2001-01-25 2001-02-22 Gainful Plan Limited Method of preparing biological materials and preparations produced using same
US6645170B2 (en) 2001-03-05 2003-11-11 Bioject Medical Technologies, Inc. Simplified disposable needle-free injection apparatus and method
US6471669B2 (en) 2001-03-05 2002-10-29 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US6685692B2 (en) * 2001-03-08 2004-02-03 Abbott Laboratories Drug delivery system
US6613010B2 (en) 2001-04-13 2003-09-02 Penjet Corporation Modular gas-pressured needle-less injector
JP4340067B2 (ja) 2001-04-23 2009-10-07 ウィスコンシン アルムニ リサーチ ファウンデイション 二機能性改変ハイドロゲル
WO2002089767A1 (en) 2001-05-03 2002-11-14 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
US6585685B2 (en) 2001-06-08 2003-07-01 Bioject Inc. Jet injector apparatus and method
US6752781B2 (en) * 2001-06-08 2004-06-22 Sergio Landau Durable hypodermic jet injector apparatus and method
US6648850B2 (en) 2001-06-08 2003-11-18 Bioject, Inc. Durable needle-less jet injector apparatus and method
DE10131178A1 (de) * 2001-06-29 2003-01-16 Boehringer Ingelheim Pharma Vernebler zur Applikation von Flüssigkeiten in die Augen
EP1409464A4 (en) 2001-07-16 2005-11-02 Ranbaxy Lab Ltd OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS
US6653319B1 (en) 2001-08-10 2003-11-25 University Of Kentucky Research Foundation Pharmaceutical formulation for poorly water soluble camptothecin analogues
US20030061583A1 (en) * 2001-09-14 2003-03-27 Numerical Technologies, Inc. Shape and look-up table based design rule checking (DRC) for physical verification of integrated circuit layouts
US6582422B2 (en) 2001-10-03 2003-06-24 Bausch & Lomb Incorporated Ophthalmic delivery device
EP1434530A2 (en) * 2001-10-12 2004-07-07 AMS Research Corporation Surgical instrument and method
US6824526B2 (en) 2001-10-22 2004-11-30 Penjet Corporation Engine and diffuser for use with a needle-less injector
US6939323B2 (en) 2001-10-26 2005-09-06 Massachusetts Institute Of Technology Needleless injector
EP1443992B1 (en) 2001-11-09 2007-01-03 Alza Corporation Collapsible syringe cartridge
CA2465502C (en) * 2001-11-09 2011-03-22 Pedro De La Serna Pneumatic powered autoinjector
US6607510B2 (en) 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US6676630B2 (en) * 2002-06-04 2004-01-13 Bioject Medical Technologies, Inc. Needle-free injection system
TWI314464B (en) 2002-06-24 2009-09-11 Alza Corp Reusable, spring driven autoinjector
SE0202063D0 (sv) 2002-07-03 2002-07-03 Pharmacia Ab Jet injector and method for its operation and production
US6792586B2 (en) 2002-07-23 2004-09-14 Sun Microsystems, Inc. Correction of spacing violations between wide class objects of dummy geometries
US6718527B2 (en) * 2002-07-23 2004-04-06 Sun Microsystems, Inc. Automated design rule violation correction when adding dummy geometries to a design layout
US6816998B2 (en) 2002-07-23 2004-11-09 Sun Microsystems, Inc. Correction of spacing violations between dummy geometries and wide class objects of design geometries
US6772401B2 (en) 2002-07-23 2004-08-03 Sun Microsystems Inc Correction of spacing violations between design geometries and wide class objects of dummy geometries
US6892363B2 (en) 2002-07-23 2005-05-10 Sun Microsystems, Inc. Correction of width violations of dummy geometries
WO2004011065A1 (en) 2002-07-31 2004-02-05 Alza Corporation Injection device providing automatic needle retraction
JP3828476B2 (ja) * 2002-10-15 2006-10-04 株式会社センサータ・テクノロジーズジャパン 無通電式密閉型モータプロテクタ
AU2003294935A1 (en) 2003-02-25 2004-09-17 F. Hoffmann-La Roche Ag Needleless hypodermic injection device with non-electric primer ignition means
US7203490B2 (en) 2003-03-24 2007-04-10 Atc Technologies, Llc Satellite assisted push-to-send radioterminal systems and methods
AU2004232366A1 (en) 2003-04-21 2004-11-04 Corium International, Inc. Apparatus and methods for repetitive microjet drug delivery
JP2005204837A (ja) * 2004-01-21 2005-08-04 Kitakyushu Foundation For The Advancement Of Industry Science & Technology 薬液放出制御用マイクロ液体デバイスおよびその製造方法
CN2680281Y (zh) * 2004-02-03 2005-02-23 中国人民解放军第三○二医院 粉末无针注射给药装置
WO2005084748A1 (en) * 2004-03-04 2005-09-15 Hadasit Medical Research Services & Development Company Ltd. Safe device for iontophoretic delivery of drugs
US20070055199A1 (en) 2005-08-10 2007-03-08 Gilbert Scott J Drug delivery device for buccal and aural applications and other areas of the body difficult to access

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CN1911465A (zh) 2007-02-14
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