BRPI0606108A2 - processo de tratamento - Google Patents
processo de tratamentoInfo
- Publication number
- BRPI0606108A2 BRPI0606108A2 BRPI0606108-7A BRPI0606108A BRPI0606108A2 BR PI0606108 A2 BRPI0606108 A2 BR PI0606108A2 BR PI0606108 A BRPI0606108 A BR PI0606108A BR PI0606108 A2 BRPI0606108 A2 BR PI0606108A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment process
- deplete
- antibodies
- patient
- cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64405905P | 2005-01-13 | 2005-01-13 | |
| PCT/US2006/001361 WO2006076651A2 (en) | 2005-01-13 | 2006-01-12 | Treatment method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0606108A2 true BRPI0606108A2 (pt) | 2009-06-02 |
Family
ID=36678251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0606108-7A BRPI0606108A2 (pt) | 2005-01-13 | 2006-01-12 | processo de tratamento |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20060188495A1 (no) |
| EP (1) | EP1841454A4 (no) |
| JP (1) | JP2008526998A (no) |
| KR (1) | KR20070104593A (no) |
| CN (1) | CN101102793A (no) |
| AU (1) | AU2006204757A1 (no) |
| BR (1) | BRPI0606108A2 (no) |
| CA (1) | CA2590163A1 (no) |
| DO (1) | DOP2006000013A (no) |
| GT (1) | GT200600020A (no) |
| IL (1) | IL183889A0 (no) |
| MX (1) | MX2007008218A (no) |
| NO (1) | NO20074130L (no) |
| RU (1) | RU2007130688A (no) |
| SV (1) | SV2006002375A (no) |
| TW (1) | TW200637574A (no) |
| WO (1) | WO2006076651A2 (no) |
| ZA (1) | ZA200705459B (no) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE311199T1 (de) | 1999-05-07 | 2005-12-15 | Genentech Inc | Behandlung von autoimmunkrankheiten mit antagonisten die oberflächenmarker von b zellen binden |
| PT1692182E (pt) | 2003-11-05 | 2010-05-13 | Roche Glycart Ag | Anticorpos de cd20 com uma afinidade de ligação acrescida ao receptor fc e uma função efectora acrescida |
| EA012464B1 (ru) | 2004-08-04 | 2009-10-30 | Эпплайд Молекьюлар Эволюшн, Инк. | Антитело против cd20 и его применение |
| WO2006116369A2 (en) * | 2005-04-22 | 2006-11-02 | Genentech, Inc. | Method for treating dementia or alzheimer's disease with a cd20 antibody |
| EP1878747A1 (en) | 2006-07-11 | 2008-01-16 | greenovation Biotech GmbH | Glyco-engineered antibodies |
| GB0707208D0 (en) * | 2007-04-13 | 2007-05-23 | Istituto Superiore Di Sanito | Novel disease treatments |
| GB0718684D0 (en) * | 2007-09-24 | 2007-10-31 | Roche Products Ltd | Treatment method |
| TW201438738A (zh) | 2008-09-16 | 2014-10-16 | 建南德克公司 | 治療進展型多發性硬化症之方法 |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| JP5828151B6 (ja) * | 2009-01-06 | 2018-09-19 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | アテローム性動脈硬化の処置のためのb細胞枯渇剤 |
| US8815242B2 (en) * | 2009-05-27 | 2014-08-26 | Synageva Biopharma Corp. | Avian derived antibodies |
| RU2012109451A (ru) * | 2009-08-14 | 2013-09-27 | Роше Гликарт Аг | Комбинированная терапия на основе афукозилированного антитела к cd20 в сочетании с флударабином и/или митоксантроном |
| AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
| CN102050877B (zh) * | 2009-10-30 | 2014-05-07 | 上海抗体药物国家工程研究中心有限公司 | 抗人cd20人源化抗体、其制备方法及用途 |
| JP2013517329A (ja) * | 2010-01-20 | 2013-05-16 | ベイヒル セラピューティクス インコーポレーティッド | 自己免疫疾患を処置するための併用治療 |
| US9173961B2 (en) | 2010-02-10 | 2015-11-03 | Immunogen, Inc. | CD20 antibodies and uses thereof |
| FR2962908A1 (fr) * | 2010-07-20 | 2012-01-27 | Lfb Biotechnologies | Formulation d'anticorps anti-cd20 |
| BR112013002535A2 (pt) | 2010-08-03 | 2019-09-24 | F. Hoffmann - La Roche Ag | biomarcadores de leucemia linfocítica crônica (cll) |
| JP2014506258A (ja) * | 2011-01-10 | 2014-03-13 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 新規使用 |
| US20130243750A1 (en) | 2012-01-31 | 2013-09-19 | Genentech, Inc. | Anti-ige antibodies and methods using same |
| US20160228371A1 (en) * | 2013-10-18 | 2016-08-11 | Abbvie Inc. | Stable solid units and methods of making the same |
| GB201516836D0 (en) * | 2015-09-23 | 2015-11-04 | Glaxosmithkline Ip No 2 Ltd | Dosing regimen of combination |
| AR106188A1 (es) | 2015-10-01 | 2017-12-20 | Hoffmann La Roche | Anticuerpos anti-cd19 humano humanizados y métodos de utilización |
| CN112805566A (zh) * | 2019-07-29 | 2021-05-14 | 上海谷森医药有限公司 | 用于吸入治疗肺癌的抗体类药物制剂 |
| EP4347647A1 (en) * | 2021-06-01 | 2024-04-10 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Use of b cell depleting agents for the treatment of rheumatic heart disease |
| EP4433506A1 (en) | 2021-11-16 | 2024-09-25 | Genentech, Inc. | Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5576195A (en) * | 1985-11-01 | 1996-11-19 | Xoma Corporation | Vectors with pectate lyase signal sequence |
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US6893625B1 (en) * | 1986-10-27 | 2005-05-17 | Royalty Pharma Finance Trust | Chimeric antibody with specificity to human B cell surface antigen |
| IL85035A0 (en) * | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5506126A (en) * | 1988-02-25 | 1996-04-09 | The General Hospital Corporation | Rapid immunoselection cloning method |
| US4861579A (en) * | 1988-03-17 | 1989-08-29 | American Cyanamid Company | Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies |
| ATE255131T1 (de) * | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| US7744877B2 (en) * | 1992-11-13 | 2010-06-29 | Biogen Idec Inc. | Expression and use of anti-CD20 Antibodies |
| US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| DE69303494T2 (de) * | 1992-11-13 | 1997-01-16 | Idec Pharma Corp | Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma |
| US5595721A (en) * | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| US20010056066A1 (en) * | 1996-07-26 | 2001-12-27 | Smithkline Beecham Corporation | Method of treating immune cell mediated systemic diseases |
| US6306393B1 (en) * | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| US6171586B1 (en) * | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| WO1999002567A2 (en) * | 1997-07-08 | 1999-01-21 | Board Of Regents, The University Of Texas System | Compositions and methods for producing homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells |
| US6242195B1 (en) * | 1998-04-02 | 2001-06-05 | Genentech, Inc. | Methods for determining binding of an analyte to a receptor |
| US6528624B1 (en) * | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
| US6194551B1 (en) * | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| PL195870B1 (pl) * | 1998-08-11 | 2007-11-30 | Biogen Idec Inc | Zastosowanie przeciwciała anty-CD20, zastosowanieznakowanego radioaktywnie przeciwciała anty-CD20,zastosowanie przeciwciała anty-CD20 do przygotowania leku zwierającego przeciwciało i chemioterapięoraz zastosowanie przeciwciała anty-CD20 do przygotowania leku zawierającego przeciwciało i szpik kostny |
| US6224866B1 (en) * | 1998-10-07 | 2001-05-01 | Biocrystal Ltd. | Immunotherapy of B cell involvement in progression of solid, nonlymphoid tumors |
| EP1035172A3 (en) * | 1999-03-12 | 2002-11-27 | Fuji Photo Film Co., Ltd. | Azomethine compound and oily magenta ink |
| EP1194167B1 (en) * | 1999-06-09 | 2009-08-19 | Immunomedics, Inc. | Immunotherapy of autoimmune disorders using antibodies which target b-cells |
| DE19930748C2 (de) * | 1999-07-02 | 2001-05-17 | Infineon Technologies Ag | Verfahren zur Herstellung von EEPROM- und DRAM-Grabenspeicherzellbereichen auf einem Chip |
| US20020006404A1 (en) * | 1999-11-08 | 2002-01-17 | Idec Pharmaceuticals Corporation | Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications |
| CA2390412A1 (en) * | 1999-11-08 | 2001-05-17 | Idec Pharmaceuticals Corporation | Treatment of b cell malignancies using anti-cd40l antibodies in combination with anti-cd20 antibodies and/or chemotherapeutics and radiotherapy |
| JP2003528155A (ja) * | 2000-03-24 | 2003-09-24 | カイロン コーポレイション | Cd20に対する抗体とインターロイキン−2との組み合わせを用いる非ホジキンリンパ腫の治療方法 |
| US20030185796A1 (en) * | 2000-03-24 | 2003-10-02 | Chiron Corporation | Methods of therapy for non-hodgkin's lymphoma |
| CN1981868A (zh) * | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗-cd20在b细胞淋巴瘤治疗中的联合应用 |
| AU2001247616B2 (en) * | 2000-04-11 | 2007-06-14 | Genentech, Inc. | Multivalent antibodies and uses therefor |
| EP1286692A4 (en) * | 2000-04-25 | 2004-11-17 | Idec Pharma Corp | INTRATHECAL ADMINISTRATION OF RITUXIMAB FOR THE TREATMENT OF LYMPHOMAS OF THE CENTRAL NERVOUS SYSTEM |
| AU6836301A (en) * | 2000-06-20 | 2002-01-02 | Idec Pharma Corp | Treatment of b-cell associated diseases such as malignancies and autoimmune diseases using a cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination |
| WO2001097843A2 (en) * | 2000-06-22 | 2001-12-27 | University Of Iowa Research Foundation | Methods for enhancing antibody-induced cell lysis and treating cancer |
| US20020058029A1 (en) * | 2000-09-18 | 2002-05-16 | Nabil Hanna | Combination therapy for treatment of autoimmune diseases using B cell depleting/immunoregulatory antibody combination |
| KR20100031769A (ko) * | 2000-12-28 | 2010-03-24 | 알투스 파마슈티컬스 인코포레이티드 | 전항체 및 이의 단편의 결정과 이의 제조 및 사용 방법 |
| US20030103971A1 (en) * | 2001-11-09 | 2003-06-05 | Kandasamy Hariharan | Immunoregulatory antibodies and uses thereof |
| ES2364816T3 (es) * | 2001-04-02 | 2011-09-14 | Genentech, Inc. | Terapia de combinación. |
| US8056639B2 (en) * | 2001-07-03 | 2011-11-15 | Emanuel Kulhanek | Well string injection system and method |
| GB0120747D0 (en) * | 2001-08-25 | 2001-10-17 | Lucas Western Inc | Control method |
| ATE443259T1 (de) * | 2001-09-20 | 2009-10-15 | Univ Texas | Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper- komplexe mit elisa-tests |
| KR100988949B1 (ko) * | 2001-10-25 | 2010-10-20 | 제넨테크, 인크. | 당단백질 조성물 |
| WO2003050358A1 (en) * | 2001-12-12 | 2003-06-19 | Trevor Loffel | A cellular honeycomb type reinforcing structure, and a method and apparatus for forming the structure |
| US20040093621A1 (en) * | 2001-12-25 | 2004-05-13 | Kyowa Hakko Kogyo Co., Ltd | Antibody composition which specifically binds to CD20 |
| RU2004127458A (ru) * | 2002-02-14 | 2005-10-27 | Иммуномедикс, Инк. (Us) | Анти-cd20 антитела, их гибридные белки и способы их использования |
| US20030180292A1 (en) * | 2002-03-14 | 2003-09-25 | Idec Pharmaceuticals | Treatment of B cell malignancies using anti-CD40L antibodies in combination with anti-CD20 antibodies and/or chemotherapeutics and radiotherapy |
| US20030219818A1 (en) * | 2002-05-10 | 2003-11-27 | Bohen Sean P. | Methods and compositions for determining neoplastic disease responsiveness to antibody therapy |
| US7341618B2 (en) * | 2002-10-24 | 2008-03-11 | Georgia Tech Research Corporation | Filters and methods of making and using the same |
| EP1944320A1 (en) * | 2002-12-16 | 2008-07-16 | Genentech, Inc. | Immunoglobulin variants and uses thereof |
| SI1613350T1 (sl) * | 2003-04-09 | 2009-08-31 | Genentech Inc | Zdravljenje avtoimunske bolezni pri bolniku z neustreznim odzivom na inhibitor TNF-alfa |
| KR101351122B1 (ko) * | 2003-05-09 | 2014-01-14 | 듀크 유니버시티 | Cd20-특이적 항체 및 이를 이용한 방법 |
| PT2272868E (pt) * | 2003-06-05 | 2015-07-07 | Genentech Inc | Terapêutica de combinação para distúrbios de células b |
| US6942551B2 (en) * | 2003-11-26 | 2005-09-13 | New Archery Products Corp. | Method for forming a cutting edge along an edge portion of a blade stock |
| EP1735000A2 (en) * | 2004-04-16 | 2006-12-27 | Genentech, Inc. | Method for augmenting b cell depletion |
| EP1753455A2 (en) * | 2004-06-04 | 2007-02-21 | Genentech, Inc. | Method for treating multiple sclerosis |
| CA2568336A1 (en) * | 2004-06-04 | 2005-12-22 | Genentech, Inc. | Method for treating lupus |
| US7193144B2 (en) * | 2005-01-31 | 2007-03-20 | Pioneer Hi-Bred International, Inc. | Inbred corn line PHCJP |
-
2006
- 2006-01-12 GT GT200600020A patent/GT200600020A/es unknown
- 2006-01-12 EP EP06718438A patent/EP1841454A4/en not_active Withdrawn
- 2006-01-12 MX MX2007008218A patent/MX2007008218A/es not_active Application Discontinuation
- 2006-01-12 SV SV2006002375A patent/SV2006002375A/es not_active Application Discontinuation
- 2006-01-12 KR KR1020077018412A patent/KR20070104593A/ko not_active Withdrawn
- 2006-01-12 BR BRPI0606108-7A patent/BRPI0606108A2/pt not_active IP Right Cessation
- 2006-01-12 JP JP2007551434A patent/JP2008526998A/ja active Pending
- 2006-01-12 CA CA002590163A patent/CA2590163A1/en not_active Abandoned
- 2006-01-12 AU AU2006204757A patent/AU2006204757A1/en not_active Abandoned
- 2006-01-12 US US11/332,194 patent/US20060188495A1/en not_active Abandoned
- 2006-01-12 DO DO2006000013A patent/DOP2006000013A/es unknown
- 2006-01-12 ZA ZA200705459A patent/ZA200705459B/xx unknown
- 2006-01-12 CN CNA2006800022822A patent/CN101102793A/zh active Pending
- 2006-01-12 TW TW095101252A patent/TW200637574A/zh unknown
- 2006-01-12 WO PCT/US2006/001361 patent/WO2006076651A2/en not_active Ceased
- 2006-01-12 RU RU2007130688/14A patent/RU2007130688A/ru not_active Application Discontinuation
-
2007
- 2007-06-13 IL IL183889A patent/IL183889A0/en unknown
- 2007-08-10 NO NO20074130A patent/NO20074130L/no not_active Application Discontinuation
- 2007-10-30 US US11/929,950 patent/US20080095771A1/en not_active Abandoned
-
2008
- 2008-05-21 US US12/125,037 patent/US20080299117A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080095771A1 (en) | 2008-04-24 |
| CA2590163A1 (en) | 2006-07-20 |
| SV2006002375A (es) | 2006-05-15 |
| US20060188495A1 (en) | 2006-08-24 |
| ZA200705459B (en) | 2008-09-25 |
| IL183889A0 (en) | 2007-10-31 |
| KR20070104593A (ko) | 2007-10-26 |
| AU2006204757A1 (en) | 2006-07-20 |
| DOP2006000013A (es) | 2006-07-15 |
| CN101102793A (zh) | 2008-01-09 |
| MX2007008218A (es) | 2007-08-17 |
| JP2008526998A (ja) | 2008-07-24 |
| EP1841454A2 (en) | 2007-10-10 |
| WO2006076651A3 (en) | 2006-11-30 |
| WO2006076651A2 (en) | 2006-07-20 |
| US20080299117A1 (en) | 2008-12-04 |
| NO20074130L (no) | 2007-10-09 |
| TW200637574A (en) | 2006-11-01 |
| RU2007130688A (ru) | 2009-02-20 |
| EP1841454A4 (en) | 2009-07-22 |
| GT200600020A (es) | 2006-11-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200637574A (en) | Treatment method | |
| EA200901211A1 (ru) | Антигены белка с5 и их применение | |
| EA201001695A1 (ru) | Применение эпотилона d для лечения заболеваний, связанных с тау-белком | |
| CY1120102T1 (el) | Συνθεσεις και μεθοδοι για μειωση τριγλυκεριδιων χωρις αυξηση επιπεδων ldl-c σε ενα υποκειμενο επι ταυτοχρονης θεραπειας στατινης | |
| AU2011328009A8 (en) | Compounds and methods for treating pain | |
| CY1121065T1 (el) | Αναστολεις ιβατ για την αγωγη ηπατικων νοσων | |
| EA201170465A1 (ru) | Способы лечения прогрессирующего множественного склероза | |
| BR112013029330A8 (pt) | uso de anticorpo imunoconjugado maytansinoide anti-cd19 para o tratamento de sintomas de doenças de célula-b | |
| EA201590833A1 (ru) | Антитела для лечения и профилактики болезни альцгеймера и их применение | |
| EA201001372A1 (ru) | Формы рифаксимина и их применение | |
| EA200970747A1 (ru) | Антагонисты активина-actriia и применение для стимуляции роста кости у больных раком | |
| EA201101521A1 (ru) | Способы лечения онкологических заболеваний, использующие эпиметаболические переключатели, многоаспектные внутриклеточные молекулы или факторы влияния | |
| MX346450B (es) | Composiciones y métodos para el tratamiento de la enfermedad celíaca. | |
| PH12013501490A1 (en) | Methods for diagnosing and treating eye-length related disorders | |
| NZ596187A (en) | Use of an anti-tau ps422 antibody for the treatment of brain diseases | |
| NO20083002L (no) | Fremgangsmate for anvendelse av CD40-bindende forbindelser | |
| PH12013501636A1 (en) | Treatment of osteoarthritis and pain | |
| CR9512A (es) | Metodos para el tratamiento de tumores de cerebro con anticuerpos | |
| BRPI0818215B8 (pt) | composições para cuidados com os cabelos e métodos cosméticos de tratamento dos cabelos | |
| EA201490746A2 (ru) | Применение прогестерона при профилактике и после острого периода для улучшения исходов, связанных с сотрясением мозга | |
| TW200728466A (en) | Antibody molecules having specificity for human IL-6 | |
| EA201492259A1 (ru) | Терапевтические применения фракций мастиковой смолы | |
| MY168748A (en) | Anti-asic1 antibodies and uses thereof | |
| EA201170356A1 (ru) | Полиморфные и аморфные формы лакозамида и аморфные композиции | |
| WO2010025321A3 (en) | Method for treating multiple sclerosis patients with anti-il2r antibodies |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 6A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012. |