BRPI0606189A2 - composição, vacina e método para proteger um animal porcino de infecção por um vìrus de prrs, célula hospedeira transfectada, método para fazer um vìrus de prrs geneticamente modificado e atenuado - Google Patents

composição, vacina e método para proteger um animal porcino de infecção por um vìrus de prrs, célula hospedeira transfectada, método para fazer um vìrus de prrs geneticamente modificado e atenuado

Info

Publication number
BRPI0606189A2
BRPI0606189A2 BRPI0606189-3A BRPI0606189A BRPI0606189A2 BR PI0606189 A2 BRPI0606189 A2 BR PI0606189A2 BR PI0606189 A BRPI0606189 A BR PI0606189A BR PI0606189 A2 BRPI0606189 A2 BR PI0606189A2
Authority
BR
Brazil
Prior art keywords
prrs virus
genetically modified
vaccine
protecting
composition
Prior art date
Application number
BRPI0606189-3A
Other languages
English (en)
Inventor
Dongwan Yoo
Changhee Lee
Jay Gregory Calvert
Siao-Kun Welch
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BRPI0606189A2 publication Critical patent/BRPI0606189A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation
    • C12N2770/10062—Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

COMPOSIçãO, VACINA E MéTODO PARA PROTEGER UM ANIMAL PORCINO DE INFECçãO POR UM VìRUS DE PRRS, CéLULA HOSPEDEIRA TRANSFECTADA, MéTODO PARA FAZER UM VìRUS DE PRRS GENETICAMENTE MODIFICADO E ATENUADO. A presente invenção refere-se a um vírus de PRRS geneticamente modificado e um polinucleotídeo que o codifica. Vacinas que compreendem o vírus geneticamente modificado e os polinucleotídeos também são fornecidos.
BRPI0606189-3A 2005-02-25 2006-02-13 composição, vacina e método para proteger um animal porcino de infecção por um vìrus de prrs, célula hospedeira transfectada, método para fazer um vìrus de prrs geneticamente modificado e atenuado BRPI0606189A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65652305P 2005-02-25 2005-02-25
US73066305P 2005-10-27 2005-10-27
PCT/IB2006/000376 WO2006129139A1 (en) 2005-02-25 2006-02-13 N protein mutants of porcine reproductive and respiratory syndrome virus

Publications (1)

Publication Number Publication Date
BRPI0606189A2 true BRPI0606189A2 (pt) 2009-06-09

Family

ID=36218763

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606189-3A BRPI0606189A2 (pt) 2005-02-25 2006-02-13 composição, vacina e método para proteger um animal porcino de infecção por um vìrus de prrs, célula hospedeira transfectada, método para fazer um vìrus de prrs geneticamente modificado e atenuado

Country Status (15)

Country Link
US (3) US7544362B1 (pt)
EP (1) EP1856141A1 (pt)
JP (1) JP4320357B2 (pt)
KR (2) KR20100090311A (pt)
CN (1) CN101128478B (pt)
AR (1) AR052392A1 (pt)
AU (1) AU2006253891B2 (pt)
BR (1) BRPI0606189A2 (pt)
CA (1) CA2599322C (pt)
MX (1) MX2007009060A (pt)
NO (1) NO20074885L (pt)
NZ (1) NZ561848A (pt)
RU (1) RU2381035C2 (pt)
TW (1) TWI366602B (pt)
WO (1) WO2006129139A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2381035C2 (ru) * 2005-02-25 2010-02-10 Пфайзер Продактс Инк. Композиция для защиты свиней от инфекции ррсс-вируса (варианты) и вакцина, содержащая указанную композицию (варианты)
CN102256997A (zh) 2008-10-16 2011-11-23 美国辉瑞有限公司 细环病毒分离株和组合物
US8846388B2 (en) 2009-10-16 2014-09-30 Zoetis Llc Infectious clones of torque teno virus
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
BR112013030321A2 (pt) 2011-05-27 2017-07-11 Sinovet Beijing Biotechnology Co Ltd composição de vacina, método para preparar a composição de vacina, uso da composição de vacina, método para imunizar um porco, cepa de vacina contra csfv e uso de uma célula no cultivo de uma cepa de vacina contra csfv.
EP2718429A1 (en) 2011-06-08 2014-04-16 Zoetis LLC Infectious clones of torque teno virus
CN103732250A (zh) * 2011-06-14 2014-04-16 全球免疫股份有限公司 基于酵母的治疗或预防丁型肝炎病毒感染的组合物和方法
CA2871786C (en) * 2012-04-24 2021-11-16 Ohio State Innovation Foundation Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
CA2872789C (en) * 2012-05-17 2019-09-03 Zoetis Llc Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning
KR102276341B1 (ko) * 2020-01-29 2021-07-12 주식회사 바이오포아 유럽형 돼지 생식기 호흡기 증후군 바이러스의 제조 방법 및 이의 용도
KR102402645B1 (ko) * 2020-01-29 2022-05-26 주식회사 바이오포아 유럽형 돼지 생식기 호흡기 증후군 바이러스의 변이주 및 이를 포함하는 백신 조성물
EP4098741A4 (en) * 2020-01-29 2024-04-03 Biopoa, Inc. MUTANT STRAIN OF EUROPEAN SWINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, AND VACCINE USING SAME
CN114315984B (zh) * 2021-12-29 2023-02-03 中国农业科学院兰州兽医研究所 一种用于制备prrsv基因ii型表位缺失疫苗毒株的n蛋白表位突变标记及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
CA2290220C (en) * 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
CA2366072C (en) * 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
EP1254213A2 (en) * 2000-01-26 2002-11-06 Boehringer Ingelheim Vetmedica Gmbh Recombinant attenuation of prrsv
RU2003129068A (ru) * 2001-03-09 2005-04-10 Бёрингер Ингельхайм Ветмедика Гмбх (De) Штаммы вируса репродуктивного и респираторного синдрома свиней (prrs) с ослабленной жизнеспособностью
EP1397498A1 (en) * 2001-05-21 2004-03-17 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Delections in arterivirus replicons
RU2381035C2 (ru) * 2005-02-25 2010-02-10 Пфайзер Продактс Инк. Композиция для защиты свиней от инфекции ррсс-вируса (варианты) и вакцина, содержащая указанную композицию (варианты)

Also Published As

Publication number Publication date
US8128937B2 (en) 2012-03-06
NO20074885L (no) 2007-11-22
CN101128478A (zh) 2008-02-20
NZ561848A (en) 2010-02-26
AR052392A1 (es) 2007-03-14
TW200641126A (en) 2006-12-01
US20100136051A1 (en) 2010-06-03
JP2008531006A (ja) 2008-08-14
KR20100090311A (ko) 2010-08-13
US7544362B1 (en) 2009-06-09
CN101128478B (zh) 2013-08-14
US20090226486A1 (en) 2009-09-10
TWI366602B (en) 2012-06-21
MX2007009060A (es) 2007-09-11
RU2007131536A (ru) 2009-03-27
JP4320357B2 (ja) 2009-08-26
US20090130143A1 (en) 2009-05-21
KR20070095453A (ko) 2007-09-28
EP1856141A1 (en) 2007-11-21
AU2006253891B2 (en) 2011-12-01
CA2599322C (en) 2013-09-03
KR100996105B1 (ko) 2010-11-22
WO2006129139A1 (en) 2006-12-07
AU2006253891A1 (en) 2006-12-07
RU2381035C2 (ru) 2010-02-10
CA2599322A1 (en) 2006-12-07

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements