BRPI0611954A2 - processos para a produÇço de compostos de anel fundido policÍclico - Google Patents

processos para a produÇço de compostos de anel fundido policÍclico

Info

Publication number
BRPI0611954A2
BRPI0611954A2 BRPI0611954-9A BRPI0611954A BRPI0611954A2 BR PI0611954 A2 BRPI0611954 A2 BR PI0611954A2 BR PI0611954 A BRPI0611954 A BR PI0611954A BR PI0611954 A2 BRPI0611954 A2 BR PI0611954A2
Authority
BR
Brazil
Prior art keywords
ring compounds
production
fused ring
polycyclic fused
polycycic
Prior art date
Application number
BRPI0611954-9A
Other languages
English (en)
Inventor
Phong Vu
Robert A Holton
Original Assignee
Univ Florida State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State Res Found filed Critical Univ Florida State Res Found
Publication of BRPI0611954A2 publication Critical patent/BRPI0611954A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • C07F7/0838—Compounds with one or more Si-O-Si sequences
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • C07F7/0838—Compounds with one or more Si-O-Si sequences
    • C07F7/0872—Preparation and treatment thereof
    • C07F7/0874—Reactions involving a bond of the Si-O-Si linkage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCESSOS PARA A PRODUÇçO DE COMPOSTOS DE ANEL FUNDIDO POLICÍCLICO. A presente invenção refere-se a processos para a produção de compostos de anel fundido policíclico. Os compostos de anel fundido policíclico são produzidos protegendo um poliol do anel fundido policíclico com um grupo de proteção com base em silício de ligação e ligando uma cadeia lateral adequada. Novos compostos de anel fundido policíclico e com postos intermediários são também descritos.
BRPI0611954-9A 2005-06-10 2006-06-08 processos para a produÇço de compostos de anel fundido policÍclico BRPI0611954A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68942505P 2005-06-10 2005-06-10
US72452705P 2005-10-07 2005-10-07
US78894306P 2006-04-04 2006-04-04
PCT/US2006/022213 WO2006135655A2 (en) 2005-06-10 2006-06-08 Processes for the production of polycyclic fused ring compounds

Publications (1)

Publication Number Publication Date
BRPI0611954A2 true BRPI0611954A2 (pt) 2009-04-28

Family

ID=37451161

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0611954-9A BRPI0611954A2 (pt) 2005-06-10 2006-06-08 processos para a produÇço de compostos de anel fundido policÍclico

Country Status (11)

Country Link
US (2) US7667055B2 (pt)
EP (1) EP1919926A2 (pt)
JP (1) JP2008545791A (pt)
KR (1) KR20080030013A (pt)
AU (1) AU2006258065A1 (pt)
BR (1) BRPI0611954A2 (pt)
CA (1) CA2610925A1 (pt)
IL (1) IL187860A0 (pt)
MX (1) MX2007015595A (pt)
TW (1) TW200718704A (pt)
WO (1) WO2006135655A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1303077C (zh) * 2004-01-16 2007-03-07 桂林晖昂生化药业有限责任公司 合成紫杉烷的制备工艺
JP2008546646A (ja) * 2005-06-10 2008-12-25 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド β−ラクタムの鏡像異性体混合物の分離
JP4833126B2 (ja) * 2007-03-26 2011-12-07 Ｎｔｎ株式会社 潤滑剤劣化検出装置および検出装置付き軸受

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
US5284865A (en) * 1991-09-23 1994-02-08 Holton Robert A Cyclohexyl substituted taxanes and pharmaceutical compositions containing them
US5430160A (en) * 1991-09-23 1995-07-04 Florida State University Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
US5399726A (en) * 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
FR2697447B1 (fr) * 1992-11-05 1995-01-13 Inst Francais Du Petrole Dispositif et procédé pour effectuer la séparation de phases par filtration et centrifugation.
US5602246A (en) * 1992-11-25 1997-02-11 Schering Aktiengesellschaft Process for the preparation of fludarabine or fludarabine phosphate from guanosine
ZA94128B (en) 1993-02-01 1994-08-19 Univ New York State Res Found Process for the preparation of taxane derivatives and betalactam intermediates therefor
US5703247A (en) 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
US5763477A (en) * 1994-07-22 1998-06-09 Dr. Reddy's Research Foundation Taxane derivatives from 14-β-hydroxy-10 deacetylbaccatin III
US5760251A (en) * 1995-08-11 1998-06-02 Sepracor, Inc. Taxol process and compounds
FR2740451B1 (fr) * 1995-10-27 1998-01-16 Seripharm Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
EP0933360A1 (en) * 1997-12-22 1999-08-04 Pharmachemie B.V. Synthesis of new beta-lactams
US6997821B2 (en) * 1999-11-01 2006-02-14 Callaway Golf Company Golf club head
US6479679B1 (en) 2001-04-25 2002-11-12 Napro Biotherapeutics, Inc. Two-step conversion of protected taxane ester to paclitaxel
EP1537094B1 (en) 2002-08-04 2014-07-02 Phyton Holdings, LLC Methods for converting taxane amides to paclitaxel or other taxanes
DE10243564B4 (de) * 2002-09-19 2006-11-30 Siemens Ag Schaltungsanordnung zur Mittelwertbildung
US20050288521A1 (en) 2004-06-29 2005-12-29 Phytogen Life Sciences Inc. Semi-synthetic conversion of paclitaxel to docetaxel
EP3345631A1 (en) 2005-02-18 2018-07-11 Abraxis BioScience, LLC Drugs with improved hydrophobicity for incorporation in medical devices

Also Published As

Publication number Publication date
US20100228038A1 (en) 2010-09-09
WO2006135655A2 (en) 2006-12-21
AU2006258065A1 (en) 2006-12-21
JP2008545791A (ja) 2008-12-18
TW200718704A (en) 2007-05-16
KR20080030013A (ko) 2008-04-03
CA2610925A1 (en) 2006-12-21
US20060281934A1 (en) 2006-12-14
US7667055B2 (en) 2010-02-23
MX2007015595A (es) 2008-03-07
IL187860A0 (en) 2008-03-20
EP1919926A2 (en) 2008-05-14
WO2006135655A3 (en) 2007-02-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]