BRPI0616155A8 - Sistema de administração de gás farmacêutico a um paciente - Google Patents

Sistema de administração de gás farmacêutico a um paciente

Info

Publication number
BRPI0616155A8
BRPI0616155A8 BRPI0616155A BRPI0616155A BRPI0616155A8 BR PI0616155 A8 BRPI0616155 A8 BR PI0616155A8 BR PI0616155 A BRPI0616155 A BR PI0616155A BR PI0616155 A BRPI0616155 A BR PI0616155A BR PI0616155 A8 BRPI0616155 A8 BR PI0616155A8
Authority
BR
Brazil
Prior art keywords
patient
pharmaceutical gas
gas
pharmaceutical
desired amount
Prior art date
Application number
BRPI0616155A
Other languages
English (en)
Inventor
J Montgomery Frederick
P L Bathe Duncan
Original Assignee
Mallinckrodt Pharma Ip Trading D A C
Ino Therapeutics Llc
Therakos Inc
Mallinckrodt Critical Care Finance Inc
Mallinckrodt Ip
Mallinckrodt Hospital Products Ip Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Pharma Ip Trading D A C, Ino Therapeutics Llc, Therakos Inc, Mallinckrodt Critical Care Finance Inc, Mallinckrodt Ip, Mallinckrodt Hospital Products Ip Ltd filed Critical Mallinckrodt Pharma Ip Trading D A C
Publication of BRPI0616155A2 publication Critical patent/BRPI0616155A2/pt
Publication of BRPI0616155A8 publication Critical patent/BRPI0616155A8/pt
Publication of BRPI0616155B1 publication Critical patent/BRPI0616155B1/pt
Publication of BRPI0616155B8 publication Critical patent/BRPI0616155B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0051—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes with alarm devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0875—Connecting tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0225—Carbon oxides, e.g. Carbon dioxide
    • A61M2202/0233—Carbon monoxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/42—Rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Primary Health Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Emergency Alarm Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SISTEMA E MÉTODO DE ADMINISTRAÇÃO DE UM GÁS FARMACÊUTICO A UM PACIENTE. A presente invenção refere-se a um método e sistema para o envio de um gás farmacêutico a um paciente. O método e sistema proporcionam uma quantidade desejada de um gás farmacêutico a um paciente independente do padrão respiratório do paciente. Os gases farmacêuticos preferidos são CO e NO, ambos os quais são proporcionados como uma concentração em um gás veículo. O sistema de controle de gás determina o envio de um gás farmacêutico ao paciente para resultar na quantidade desejada conhecida (por exemplo, em moléculas, miligramas ou outras unidades quantificadas) do gás farmacêutico sendo enviado. Com a conclusão da re- ferida quantidade desejada conhecida de gás farmacêutico em uma pluralidade de respirações, o sistema pode ou terminar qualquer envio adicional de gás farmacêutico ou pode ativar um alarme para alertar ao usuário de que a quantidade conhecida foi enviada. O sistema é também dotado de funções de alarme para alertar o usuário de possíveis maus funcionamentos do sistema.
BRPI0616155A 2005-09-21 2006-09-13 sistema de administração de gás farmacêutico a um paciente BRPI0616155B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/231,554 US7523752B2 (en) 2005-09-21 2005-09-21 System and method of administering a pharmaceutical gas to a patient
US11/231,554 2005-09-21
PCT/US2006/035450 WO2007037975A2 (en) 2005-09-21 2006-09-13 System and method of administering a pharmaceutical gas to a patient

Publications (4)

Publication Number Publication Date
BRPI0616155A2 BRPI0616155A2 (pt) 2011-06-07
BRPI0616155A8 true BRPI0616155A8 (pt) 2018-04-03
BRPI0616155B1 BRPI0616155B1 (pt) 2020-11-17
BRPI0616155B8 BRPI0616155B8 (pt) 2021-05-25

Family

ID=37882847

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0616155A BRPI0616155B8 (pt) 2005-09-21 2006-09-13 sistema de administração de gás farmacêutico a um paciente

Country Status (17)

Country Link
US (11) US7523752B2 (pt)
EP (3) EP1937343B1 (pt)
JP (1) JP4994380B2 (pt)
CN (3) CN103285487B (pt)
AU (1) AU2006295150B2 (pt)
BR (1) BRPI0616155B8 (pt)
CA (2) CA2623052C (pt)
CY (2) CY1117999T1 (pt)
DK (2) DK3372269T3 (pt)
ES (3) ES2905888T3 (pt)
HU (2) HUE029106T2 (pt)
LT (1) LT3372269T (pt)
MX (2) MX370646B (pt)
PL (2) PL1937343T3 (pt)
PT (2) PT1937343T (pt)
SI (2) SI3372269T1 (pt)
WO (1) WO2007037975A2 (pt)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE529989C2 (sv) * 2004-09-03 2008-01-29 Ric Investments Llc Gasregulator
FR2875138B1 (fr) 2004-09-15 2008-07-11 Mallinckrodt Dev France Sa Procede de regulation pour un humidificateur chauffant
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US20070181126A1 (en) * 2006-02-08 2007-08-09 Tolmie Craig R Method and apparatus for ventilating a patient with a breathing gas mixture formed from nitric oxide, air, and oxygen
JP2011522621A (ja) 2008-06-06 2011-08-04 ネルコー ピューリタン ベネット エルエルシー 患者の努力に比例した換気のためのシステムおよび方法
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US8393323B2 (en) 2008-09-30 2013-03-12 Covidien Lp Supplemental gas safety system for a breathing assistance system
CA2763111C (en) 2009-05-27 2019-09-24 Ino Therapeutics Llc Devices and methods for engaging indexed valve and pressurized canister assembly with collar and for linear actuation by plunger assembly into fluid communication with device for regulating drug delivery
AU2009202685B1 (en) 2009-06-30 2010-08-19 Ino Therapeutics Llc Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
DE102010016699A1 (de) * 2010-04-29 2011-11-03 Maquet Gmbh & Co. Kg Verfahren und Vorrichtung zur Applikation mindestens eines medizinischen Gases an einen mit Hilfe eines Beatmungsgeräts beatmeten Patienten
DK2661300T3 (en) 2011-01-06 2018-01-15 Ino Therapeutics Llc Gas supply device and system
US8783250B2 (en) 2011-02-27 2014-07-22 Covidien Lp Methods and systems for transitory ventilation support
US8714154B2 (en) 2011-03-30 2014-05-06 Covidien Lp Systems and methods for automatic adjustment of ventilator settings
JP5907675B2 (ja) * 2011-06-17 2016-04-26 フクダ電子株式会社 一酸化炭素投与システム
JP6112757B2 (ja) * 2011-06-17 2017-04-12 フクダ電子株式会社 一酸化炭素投与システム
JP6112756B2 (ja) * 2011-06-17 2017-04-12 フクダ電子株式会社 一酸化炭素投与システム
US10426913B2 (en) 2011-11-07 2019-10-01 Mallinckrodt Hospital Products IP Limited Apparatus and method for monitoring nitric oxide delivery
HK1198520A1 (en) 2011-11-07 2015-05-15 Mallinckrodt Hospital Products IP Limited Apparatus and method for monitoring nitric oxide delivery
CN102500024B (zh) * 2011-12-01 2014-06-25 于邦仲 一种呼吸机流量检测系统
US8944051B2 (en) 2012-04-05 2015-02-03 Ino Therapeutics Llc Breathing apparatus detection and purging
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
TR201707036T4 (en) 2012-12-04 2018-11-21 Ino Therapeutics Llc Cannula to minimize dose dilution during administration of nitric oxide
US9604026B2 (en) * 2013-02-20 2017-03-28 Wisconsin Alumni Research Foundation Medical carbon monoxide delivery system
MX363691B (es) * 2013-03-13 2019-03-29 Mallinckrodt Hospital Products Ip Ltd Aparato y metodo para monitorizar el suministro de oxido nitrico.
ES2981406T3 (es) 2013-03-15 2024-10-08 Mallinckrodt Pharmaceuticals Ireland Ltd Administración y monitorización de óxido nítrico en fluidos ex vivo
EP3466473B1 (en) * 2013-03-15 2020-05-27 Mallinckrodt Hospital Products IP Limited Therapeutic gas delivery device with pulsed and continuous flow control
US9629358B2 (en) 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
AU2014227790B2 (en) 2013-03-15 2019-03-14 Mallinckrodt Hospital Products IP Limited Therapeutic gas delivery device with pulsed and continuous flow control
US10342948B2 (en) 2013-03-18 2019-07-09 Mallinckrodt Hospital Products IP Limited Therapeutic gas delivery device with pulsed and continuous flow control
CN103263715B (zh) * 2013-05-24 2015-12-02 史源 一氧化碳吸入仪
US10512741B2 (en) 2013-09-13 2019-12-24 Mallinckrodt Hospital Products IP Limited Clinical decision support system and methods
US20150114395A1 (en) * 2013-10-29 2015-04-30 General Electric Company Method and arrangement for determining a ventilation need specific for a patient
US9381212B2 (en) 2014-01-10 2016-07-05 Mallinckrodt Hospital Products IP Limited Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
US10188822B2 (en) 2014-03-13 2019-01-29 Mallinckrodt Hospital Products IP Limited Gas delivery device and system for use in magnetic resonance imaging
US10226592B2 (en) 2014-04-01 2019-03-12 Mallinckrodt Hospital Product Ip Limited Systems and method for delivery of therapeutic gas to patients in need thereof using enhanced breathing circuit gas (BCG) flow measurement
TW201618795A (zh) * 2014-04-15 2016-06-01 波泰里斯股份有限公司 用以改良器官功能及延長器官移植物壽命之系統及方法
US10071213B2 (en) 2014-05-02 2018-09-11 Mallinckrodt Hospital Products IP Limited Systems and method for delivery of therapeutic gas to patients, in need thereof, receiving breathing gas from a ventilator that varies at least pressure and/or flow using enhanced therapeutic gas (NO) flow measurement
WO2015172160A1 (en) 2014-05-09 2015-11-12 Ino Therapeutics Llc Systems and methods for intelligent gas source management and/or systems and methods for delivery of therapeutic gas and/or enhanced performance verification for therapeutic gas delivery
US10525226B2 (en) * 2014-05-14 2020-01-07 Mallinckrodt Hospital Products IP Limited Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
US10384031B1 (en) 2014-06-20 2019-08-20 Mallinckrodt Hospital Products IP Limited Systems and methods for manufacturing and safety of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
US9808591B2 (en) 2014-08-15 2017-11-07 Covidien Lp Methods and systems for breath delivery synchronization
US10758703B2 (en) 2014-10-17 2020-09-01 Mallinckrodt Hospital Products IP Limited Systems and methods for providing a pulse of a therapeutic gas with a desired flow profile to maximize therapeutic effectiveness
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
AU2016243801B2 (en) 2015-04-02 2020-05-21 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
EP3302267A4 (en) * 2015-06-03 2019-01-16 The Regents of the University of California RECOVERY AND VENTILATION MONITOR
MX2018004020A (es) 2015-10-01 2018-09-11 Mallinckrodt Hospital Products Ip Ltd Dispositivo y método para la dispersión de no de concentración alta con gas de terapia de inhalación.
JP7045319B2 (ja) 2016-02-02 2022-03-31 マリンクロット ホスピタル プロダクツ アイピー リミテッド 呼吸ガス流の計測における中断の補償
US10398820B2 (en) 2016-02-12 2019-09-03 Mallinckrodt Hospital Products IP Limited Use and monitoring of inhaled nitric oxide with left ventricular assist devices
WO2018157175A1 (en) 2017-02-27 2018-08-30 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
BR112019016708B1 (pt) 2017-02-27 2024-01-30 Third Pole, Inc Sistemas de geração de óxido nítrico
JP2021509109A (ja) 2017-12-28 2021-03-18 ベレロフォン パルス テクノロジーズ エルエルシー 肺高血圧症の治療のための吸入用一酸化窒素のパルス投与
US11478594B2 (en) 2018-05-14 2022-10-25 Covidien Lp Systems and methods for respiratory effort detection utilizing signal distortion
US11752287B2 (en) 2018-10-03 2023-09-12 Covidien Lp Systems and methods for automatic cycling or cycling detection
WO2020142658A1 (en) 2019-01-04 2020-07-09 Bellerophon Therapeutics Use of inhaled nitric oxide (ino) for improving activity levels in patients with lung-related conditions
GB2581999B (en) * 2019-03-07 2023-01-04 Bpr Medical Ltd Gas flow alarm
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
CN114269685A (zh) 2019-05-15 2022-04-01 第三极股份有限公司 用于一氧化氮生成的电极
WO2020232414A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Architectures for production of nitric oxide
EP3741415B1 (en) * 2019-05-23 2021-09-08 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Resuscitation bag system with a gas control unit
US11324954B2 (en) 2019-06-28 2022-05-10 Covidien Lp Achieving smooth breathing by modified bilateral phrenic nerve pacing
WO2021105900A1 (en) 2019-11-25 2021-06-03 Beyond Air, Inc. System and method for delivery of gas to a tissue
EP3839959A1 (en) * 2019-12-19 2021-06-23 Koninklijke Philips N.V. Transdermal sedative release control in autonomous imaging
CN111135406B (zh) * 2020-01-10 2023-08-08 宁波戴维医疗器械股份有限公司 一种高频呼吸机
EP4069069A4 (en) 2020-01-11 2024-07-03 Third Pole, Inc. SYSTEMS AND METHODS FOR NITROGEN OXIDE PRODUCTION WITH HUMIDITY CONTROL
WO2021231363A1 (en) * 2020-05-11 2021-11-18 The United States Of America As Represented By The Secretary Of The Navy Medical ventilator and method of use
EP4167920A4 (en) 2020-06-18 2024-06-12 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11369763B2 (en) 2020-07-31 2022-06-28 Soco International Llc Respiratory ventilatory device and method of operating same
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
EP4405019A4 (en) 2021-09-23 2025-07-16 Third Pole Inc SYSTEMS AND METHODS FOR PROVIDING NITRIC OXIDE
WO2023201363A2 (en) 2022-04-14 2023-10-19 Third Pole, Inc. Delivery of medicinal gas in a liquid medium
USD1108635S1 (en) 2023-02-14 2026-01-06 Mallinckrodt Pharmaceuticals Ireland Limited Therapeutic gas delivery device
USD1087129S1 (en) 2023-02-14 2025-08-05 Mallinckrodt Pharmaceuticals Ireland Limited Display screen or portion thereof with graphical user interface
USD1069817S1 (en) 2023-02-14 2025-04-08 Mallinckrodt Pharmaceuticals Ireland Limited Display screen or portion thereof with graphical user interface
USD1061594S1 (en) 2023-02-14 2025-02-11 Mallinckrodt Pharmaceuticals Ireland Limited Display screen or portion thereof with graphical user interface
USD1060405S1 (en) 2023-02-14 2025-02-04 Mallinckrodt Pharmaceuticals Ireland Limited Display screen or portion thereof with graphical user interface
USD1092732S1 (en) 2023-02-14 2025-09-09 Mallinckrodt Pharmaceuticals Ireland Limited Injector module
USD1073017S1 (en) 2023-02-14 2025-04-29 Mallinckrodt Pharmaceuticals Ireland Limited Gas cylinder
USD1092742S1 (en) 2023-02-14 2025-09-09 Mallinckrodt Pharmaceuticals Ireland Limited Therapeutic gas cylinder bay
USD1064285S1 (en) 2023-02-14 2025-02-25 Mallinckrodt Pharmaceuticals Ireland Limited Therapeutic gas delivery cart
FR3157812B1 (fr) * 2024-01-03 2025-12-19 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3802417A (en) * 1968-12-21 1974-04-09 V Lang Device for combined monitoring and stimulation of respiration
JPS6294175A (ja) * 1985-10-18 1987-04-30 鳥取大学長 呼吸同調式ガス吹送装置および方法
EP1875917A3 (en) * 1990-12-05 2012-11-28 The General Hospital Corporation Use of NO for the treatment or prevention of reversible pulmonary vasoconstriction
US5319355A (en) * 1991-03-06 1994-06-07 Russek Linda G Alarm for patient monitor and life support equipment system
GB2279014B (en) 1993-06-02 1997-07-16 Niall Keaney Device for controlling delivery of respiratory drugs
GB9320978D0 (en) 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
US5558083A (en) * 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
JP2786808B2 (ja) 1994-02-10 1998-08-13 忠道 目黒 気相系呼吸機能の測定方法および測定結果を用いた気相系呼吸機能の健康管理方法
JP3142716B2 (ja) * 1994-04-28 2001-03-07 裕一 石部 呼吸器への一酸化窒素の供給装置
ES2267141T3 (es) * 1996-04-05 2007-03-01 The General Hospital Corporation Tratamiento de una hemoglobinopatia.
US5752504A (en) 1996-12-13 1998-05-19 Ohmeda Inc. System for monitoring therapy during calibration
US5732693A (en) 1996-10-02 1998-03-31 Ohmeda Inc. Pause control of nitric oxide therapy
CN1179331A (zh) * 1996-10-11 1998-04-22 鲍辛纳克·乔治斯 呼吸辅助设备
JPH10179742A (ja) * 1996-12-25 1998-07-07 Sumitomo Seika Chem Co Ltd 携帯用一酸化窒素−酸素ガス供給装置およびその操作方法
JP2001517108A (ja) 1997-01-17 2001-10-02 メッサー オーストリア ゲゼルシャフト ミット ベシュレンクテル ハフツング 制御されるガス供給システム
US5918596A (en) 1997-04-22 1999-07-06 Instrumentarium Corp. Special gas dose delivery apparatus for respiration equipment
US6125846A (en) 1997-05-16 2000-10-03 Datex-Ohmeda, Inc. Purge system for nitric oxide administration apparatus
US6164276A (en) * 1997-05-16 2000-12-26 Datex-Ohmeda, Inc. Accurate dose nitric oxide pulse delivery device with monitoring and alarms
US6371114B1 (en) 1998-07-24 2002-04-16 Minnesota Innovative Technologies & Instruments Corporation Control device for supplying supplemental respiratory oxygen
US6109260A (en) 1998-02-18 2000-08-29 Datex-Ohmeda, Inc. Nitric oxide administration device with timed pulse
US6089229A (en) * 1998-05-26 2000-07-18 Datex-Ohmeda, Inc. High concentration no pulse delivery device
JP2000024110A (ja) * 1998-07-16 2000-01-25 Teijin Ltd 呼吸同調型気体供給装置
FI110065B (fi) * 1998-12-08 2002-11-29 Instrumentarium Oyj Sovitelma takaisinkytketyn säätöjärjestelmän yhteydessä
US7678390B2 (en) * 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
CN2368059Y (zh) * 1999-04-21 2000-03-08 莫绪明 一氧化氮气体吸入流量控制仪
DE60027403T2 (de) * 1999-09-22 2006-10-19 Instrumentarium Corp. Verbesserung der Sauerstoffversorgung in Lebewesen mit gestörter Sauerstoffversorgung
SE9903467D0 (sv) * 1999-09-24 1999-09-24 Siemens Elema Ab Feedback control of mechanical breathing aid gas flow
US7516742B2 (en) 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6581599B1 (en) * 1999-11-24 2003-06-24 Sensormedics Corporation Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients
CN2439288Y (zh) 2000-07-27 2001-07-18 中国人民解放军第二军医大学南京军医学院 一氧化氮高频喷射通气治疗仪
US6668828B1 (en) * 2000-10-16 2003-12-30 Pulmonox Technologies Corporations System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient
JP2002143305A (ja) * 2000-11-14 2002-05-21 Gunma Koike:Kk 呼吸同調型酸素供給装置
EP1395241B9 (en) * 2001-05-25 2005-06-15 Medtronic, Inc. Implantable medical device with controllable gaseous agent release system
CA2351217C (en) * 2001-06-19 2008-12-02 Teijin Limited An apparatus for supplying a therapeutic oxygen gas
DE60209784T2 (de) * 2001-12-06 2006-11-30 Cardinal Health 303, Inc., San Diego Infusionsvorrichtung mit co2 überwachung
BRPI0307673A2 (pt) * 2002-02-13 2016-11-08 Beth Israel Hospital métodos de tratar doença vascular.
US20030189492A1 (en) * 2002-04-04 2003-10-09 Harvie Mark R. Monitoring, alarm and automatic adjustment system for users of oxygen and compressed air
RS91004A (sr) * 2002-04-15 2007-02-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education, Postupci za lečenje ileusa
US6909912B2 (en) 2002-06-20 2005-06-21 University Of Florida Non-invasive perfusion monitor and system, specially configured oximeter probes, methods of using same, and covers for probes
DE10230165A1 (de) * 2002-07-04 2004-01-15 Ino Therapeutics Gmbh Verfahren und Vorrichtung zur Administration von Kohlenmonoxid
PL377733A1 (pl) * 2002-11-07 2006-02-06 University Of Pittsburgh Of The Commonwealth System Of Higher Education Leczenie wstrząsu krwotocznego
CN2584208Y (zh) * 2003-01-22 2003-11-05 陈延航 主动按需脉冲吸氧控制器
DE10306766A1 (de) 2003-02-18 2004-08-26 Ino Therapeutics Gmbh Dosierte Abgabe eines therapeutischen Gases
DE10321448A1 (de) * 2003-05-13 2004-12-02 Ino Therapeutics Gmbh Verfahren und Vorrichtung zur kontrollierten Zumischung eines Gases oder Gasgemisches zu einem Gas(gemisch)strom
US20080029093A1 (en) 2004-05-11 2008-02-07 Alex Stenzler Intermittent Dosing Of Nitric Oxide Gas
US7690378B1 (en) * 2004-07-21 2010-04-06 Pacesetter, Inc. Methods, systems and devices for monitoring respiratory disorders
US7370651B2 (en) 2005-04-01 2008-05-13 Ric Investments, Llc Gas conserving device
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US7305988B2 (en) 2005-12-22 2007-12-11 The General Electric Company Integrated ventilator nasal trigger and gas monitoring system
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US20100175695A1 (en) 2009-01-12 2010-07-15 Mindray Ds Usa, Inc. Auxiliary gas mixing in an anesthesia system
AU2009202685B1 (en) 2009-06-30 2010-08-19 Ino Therapeutics Llc Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
DK2661300T3 (en) 2011-01-06 2018-01-15 Ino Therapeutics Llc Gas supply device and system

Also Published As

Publication number Publication date
JP4994380B2 (ja) 2012-08-08
US20120042875A1 (en) 2012-02-23
US7523752B2 (en) 2009-04-28
US20120266879A1 (en) 2012-10-25
US20130302447A1 (en) 2013-11-14
CA2623052A1 (en) 2007-04-05
JP2009508637A (ja) 2009-03-05
PT3372269T (pt) 2022-01-31
US8517015B2 (en) 2013-08-27
DK3372269T3 (da) 2022-01-31
ES2670503T3 (es) 2018-05-30
EP1937343A2 (en) 2008-07-02
CN103285487B (zh) 2016-03-02
HUE057384T2 (hu) 2022-05-28
US20200163989A1 (en) 2020-05-28
CN101312761B (zh) 2014-04-23
BRPI0616155B8 (pt) 2021-05-25
HUE029106T2 (en) 2017-02-28
US8408206B2 (en) 2013-04-02
US20130306068A1 (en) 2013-11-21
US20130298909A1 (en) 2013-11-14
AU2006295150B2 (en) 2010-09-23
US9351994B2 (en) 2016-05-31
SI1937343T1 (sl) 2016-08-31
CA2623052C (en) 2016-04-19
US20090205655A1 (en) 2009-08-20
EP2644222A1 (en) 2013-10-02
WO2007037975A3 (en) 2007-10-04
BRPI0616155B1 (pt) 2020-11-17
SI3372269T1 (sl) 2022-05-31
US20120042876A1 (en) 2012-02-23
PL1937343T3 (pl) 2016-10-31
EP1937343A4 (en) 2011-08-17
US8616204B2 (en) 2013-12-31
US8397721B2 (en) 2013-03-19
CN103285487A (zh) 2013-09-11
US8091549B2 (en) 2012-01-10
US8607792B2 (en) 2013-12-17
US20130186396A1 (en) 2013-07-25
EP2644222B1 (en) 2018-03-21
ES2905888T3 (es) 2022-04-12
HK1126150A1 (en) 2009-08-28
HK1189181A1 (zh) 2014-05-30
CA2836041A1 (en) 2007-04-05
EP3372269A1 (en) 2018-09-12
US20070062527A1 (en) 2007-03-22
DK1937343T3 (en) 2016-07-25
PT1937343T (pt) 2016-07-13
LT3372269T (lt) 2022-02-25
ES2579432T3 (es) 2016-08-11
EP1937343B1 (en) 2016-03-30
US10548920B2 (en) 2020-02-04
AU2006295150A1 (en) 2007-04-05
CN101312761A (zh) 2008-11-26
MX2019015465A (es) 2020-02-12
EP3372269B1 (en) 2021-11-10
CY1117999T1 (el) 2017-05-17
WO2007037975A2 (en) 2007-04-05
US20160271168A1 (en) 2016-09-22
CA2836041C (en) 2016-05-17
MX370646B (es) 2019-12-18
CY1125324T1 (el) 2024-02-16
CN103463720B (zh) 2017-04-12
US8720440B2 (en) 2014-05-13
BRPI0616155A2 (pt) 2011-06-07
PL3372269T3 (pl) 2022-04-25
CN103463720A (zh) 2013-12-25

Similar Documents

Publication Publication Date Title
BRPI0616155A8 (pt) Sistema de administração de gás farmacêutico a um paciente
Zhang et al. Neutrophil autophagy and NETosis in COVID-19: perspectives
MX2009003048A (es) Disposiciones a base de anticuerpo para detectar transductores de multiple señal en celulas circulantes raras.
Li et al. Decrease the flow setting to improve trans‐nasal pulmonary aerosol delivery via “high‐flow nasal cannula” to infants and toddlers
BR112012019624A2 (pt) sistema e método para administrar medicamentos a um paciente
WO2008036801A3 (en) Methods and systems of delivering medication via inhalation
BR0213397A (pt) Método para suprimento de uma mistura de gases a um paciente, sistema para suprimento de gás a um paciente, usos de halotano, de enflurano, de isoflurano, de sevoflurano e de desflurano no sistema para suprimento, sistema para suprimento de medicamento, e, método para suprimento de medicamento terapêutico
BRPI0609725B8 (pt) dispositivo de filtro de nebulizador e sistema para aerossolização de um medicamento
BRPI1006007A8 (pt) Sistema de suporte de pressão com respirações administratdas por aparelho, método para prover suporte de pressão a um paciente, sistema de suporte de pressão, e, sistema para prover o suporte de pressão a um paciente
Ahmad et al. Impact of bispectral index monitoring on fast tracking of gynecologic patients undergoing laparoscopic surgery
WO2007135578A3 (en) Warning system for timely administration of drugs that have to be administered at certain times
BRPI0516262A (pt) métodos e kits para distribuir fármacos por nebulização
UY27757A1 (es) Medicamento que contiene betamiméticos y un nuevo anticolinérgico.
Borland et al. Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized controlled trial
Martucci et al. Veno-venous ECMO in ARDS after post-traumatic pneumonectomy
NO20091628L (no) Kombinasjonsmedikament
Addis et al. Halogen gas exposure: toxic effects on the parturient
Steyl et al. A randomised controlled trial comparing quality of recovery between desflurane and isoflurane inhalation anaesthesia in patients undergoing ophthalmological surgery at a tertiary hospital in South Africa (DIQoR trial)
Vestbo et al. Translated impact on carbon footprint from choice of inhaled therapy: a Danish scenario
Carron et al. Spinal block with 1.5 mg hyperbaric bupivacaine: not successful for everyone
Chen et al. Comparison of postoperative analgesia and side effects in pediatric laparoscopic surgery with morphine and nalbuphine
Nair et al. Postoperative sore throat prevention: Is there an evidence or is it much ado about nothing?
Koumbourlis et al. Continuous inhalation of ipratropium bromide for acute asthma refractory to β2-agonist treatment
Van Velzen et al. Pharmacokinetics of nasally administered tobramycin, colistin sulphomethate sodium and a combination of tobramycin and colistin sulphomethate sodium
Rupika et al. Is This the Right Time to Consider Using Oxygen-conserving Devices in Clinical Practice?

Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: INO THERAPEUTICS LLC (US)

B25A Requested transfer of rights approved

Owner name: THERAKOS, INC. (US)

B25A Requested transfer of rights approved

Owner name: MALLINCKRODT CRITICAL CARE FINANCE INC. (US)

B25A Requested transfer of rights approved

Owner name: MALLINCKRODT PHARMA IP TRADING D.A.C. (IE)

B25A Requested transfer of rights approved

Owner name: MALLINCKRODT IP (IE)

B25A Requested transfer of rights approved

Owner name: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED (IE)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/11/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/09/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF