BRPI0619255A8 - Composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer - Google Patents

Composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer

Info

Publication number
BRPI0619255A8
BRPI0619255A8 BRPI0619255A BRPI0619255A BRPI0619255A8 BR PI0619255 A8 BRPI0619255 A8 BR PI0619255A8 BR PI0619255 A BRPI0619255 A BR PI0619255A BR PI0619255 A BRPI0619255 A BR PI0619255A BR PI0619255 A8 BRPI0619255 A8 BR PI0619255A8
Authority
BR
Brazil
Prior art keywords
compound
cancer immunotherapy
pharmaceutical composition
hydrogen atom
drug
Prior art date
Application number
BRPI0619255A
Other languages
English (en)
Inventor
Nishihara Toshio
Gotoh Masashi
Original Assignee
Int Inst Cancer Immunology Inc
Dainippon Sumitomo Pharma Co
Chugai Seiyaku Kabishiki Kaisha
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Inst Cancer Immunology Inc, Dainippon Sumitomo Pharma Co, Chugai Seiyaku Kabishiki Kaisha, Sumitomo Dainippon Pharma Co Ltd filed Critical Int Inst Cancer Immunology Inc
Publication of BRPI0619255A2 publication Critical patent/BRPI0619255A2/pt
Publication of BRPI0619255A8 publication Critical patent/BRPI0619255A8/pt
Publication of BRPI0619255B1 publication Critical patent/BRPI0619255B1/pt
Publication of BRPI0619255B8 publication Critical patent/BRPI0619255B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

COMPOSTO DE PEPTÍDEO, COMPOSIÇÃO FARMACÊUTICA, ANTICORPO, USO DO COMPOSTO E MEDICAMENTO PARA IMUNOTERAPIA DE CÂNCER. A presente invenção refere-se a um composto da fórmula (1) em que X é um resíduo de tirosina ou um resíduo de metionina; Y e Z são, cada, uma ligação simples ou similar; R1 é um átomo de hidrogênio ou similar; R2 é um grupo hidróxi ou similar; R3 é um átomo de hidrogênio, grupo alquila, grupo amino ou similar; R4 é um átomo de hidrogênio, grupo alquila, grupo carbóxi ou similar; m é 1 ou 2; e n é um número inteiro de 0 a 2, com a condição de que quando n é 0, R3 é um átomo de hidrogênio ou um grupo alquila, ou um sal farmaceuticamente aceitável do mesmo, e seu uso em imunoterapia de câncer.
BRPI0619255A 2005-11-30 2006-11-29 composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer BRPI0619255B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005346577 2005-11-30
JP2005-346577 2005-11-30
PCT/JP2006/323827 WO2007063903A1 (ja) 2005-11-30 2006-11-29 新規ペプチド化合物

Publications (4)

Publication Number Publication Date
BRPI0619255A2 BRPI0619255A2 (pt) 2011-09-27
BRPI0619255A8 true BRPI0619255A8 (pt) 2015-12-15
BRPI0619255B1 BRPI0619255B1 (pt) 2021-05-11
BRPI0619255B8 BRPI0619255B8 (pt) 2021-05-25

Family

ID=38092236

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0619255A BRPI0619255B8 (pt) 2005-11-30 2006-11-29 composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer

Country Status (18)

Country Link
US (4) US7939627B2 (pt)
EP (1) EP1961761B1 (pt)
JP (4) JP4394724B2 (pt)
KR (1) KR101385805B1 (pt)
CN (2) CN105315347A (pt)
AU (1) AU2006319892B2 (pt)
BR (1) BRPI0619255B8 (pt)
CA (1) CA2631292C (pt)
DE (1) DE602006017880D1 (pt)
DK (1) DK1961761T3 (pt)
ES (1) ES2352855T3 (pt)
HK (1) HK1221230A1 (pt)
PL (1) PL1961761T3 (pt)
PT (1) PT1961761E (pt)
RU (1) RU2424247C2 (pt)
SI (1) SI1961761T1 (pt)
TW (1) TWI372152B (pt)
WO (1) WO2007063903A1 (pt)

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Also Published As

Publication number Publication date
US9273148B2 (en) 2016-03-01
BRPI0619255B1 (pt) 2021-05-11
RU2424247C2 (ru) 2011-07-20
KR101385805B1 (ko) 2014-04-16
EP1961761B1 (en) 2010-10-27
JP5049323B2 (ja) 2012-10-17
WO2007063903A1 (ja) 2007-06-07
US9765114B2 (en) 2017-09-19
SI1961761T1 (sl) 2010-12-31
AU2006319892B2 (en) 2012-05-10
PT1961761E (pt) 2010-12-16
TW200730540A (en) 2007-08-16
HK1122819A1 (en) 2009-05-29
US20100062010A1 (en) 2010-03-11
BRPI0619255A2 (pt) 2011-09-27
JP4394724B2 (ja) 2010-01-06
US8575308B2 (en) 2013-11-05
JP2012158597A (ja) 2012-08-23
US20140046036A1 (en) 2014-02-13
CN101336249A (zh) 2008-12-31
CN105315347A (zh) 2016-02-10
JP2014080435A (ja) 2014-05-08
JPWO2007063903A1 (ja) 2009-05-07
JP2009286792A (ja) 2009-12-10
US20160168197A1 (en) 2016-06-16
AU2006319892A1 (en) 2007-06-07
HK1221230A1 (zh) 2017-05-26
EP1961761A1 (en) 2008-08-27
KR20080073356A (ko) 2008-08-08
JP5597668B2 (ja) 2014-10-01
CA2631292C (en) 2014-05-06
BRPI0619255B8 (pt) 2021-05-25
JP5800928B2 (ja) 2015-10-28
TWI372152B (en) 2012-09-11
DE602006017880D1 (pt) 2010-12-09
RU2008126305A (ru) 2010-01-10
ES2352855T3 (es) 2011-02-23
DK1961761T3 (da) 2010-11-29
PL1961761T3 (pl) 2011-04-29
CA2631292A1 (en) 2007-06-07
US7939627B2 (en) 2011-05-10
US20110229506A1 (en) 2011-09-22
EP1961761A4 (en) 2009-01-21

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