BRPI0620280B8 - método de inativação de patógenos e / ou leucócitos em concentrados de plaquetas - Google Patents

método de inativação de patógenos e / ou leucócitos em concentrados de plaquetas

Info

Publication number
BRPI0620280B8
BRPI0620280B8 BRPI0620280A BRPI0620280A BRPI0620280B8 BR PI0620280 B8 BRPI0620280 B8 BR PI0620280B8 BR PI0620280 A BRPI0620280 A BR PI0620280A BR PI0620280 A BRPI0620280 A BR PI0620280A BR PI0620280 B8 BRPI0620280 B8 BR PI0620280B8
Authority
BR
Brazil
Prior art keywords
pathogen
platelet concentrates
inactivation method
leukocytes
agitation
Prior art date
Application number
BRPI0620280A
Other languages
English (en)
Inventor
Mohr Harald
H Walker Wolfram
Original Assignee
Forschungsgemeinschaft Der Drk Blutspendedienste E V
Maco Pharma S A Laboratoires Pharmaceutiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungsgemeinschaft Der Drk Blutspendedienste E V, Maco Pharma S A Laboratoires Pharmaceutiques filed Critical Forschungsgemeinschaft Der Drk Blutspendedienste E V
Publication of BRPI0620280A2 publication Critical patent/BRPI0620280A2/pt
Publication of BRPI0620280B1 publication Critical patent/BRPI0620280B1/pt
Publication of BRPI0620280B8 publication Critical patent/BRPI0620280B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet [UV] radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

método de inativação de patógenos e/ ou leucócitos em concentrados de plaquetas. a invenção relaciona-se com um método de inativação de patógenos tais como bactérias e vírus e/ ou leucócitos em concentrados flexíveis com luz ultravíoleta usando agitação. o produto sanguíneo é embalada numa bolsa flexível para permitir a intermistura do fluido por agitação(inclinação, rotação, translação). isto é também promovido pelo enchimento da bolsa a 30% máxima da capacidade de enchimento.
BRPI0620280A 2005-12-23 2006-12-21 método de inativação de patógenos e / ou leucócitos em concentrados de plaquetas BRPI0620280B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005062410A DE102005062410A1 (de) 2005-12-23 2005-12-23 Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht
DE102005062410.3 2005-12-23
PCT/DE2006/002311 WO2007076834A1 (de) 2005-12-23 2006-12-21 Verfahren zur bestrahlung von thrombozytenkonzentraten in flexiblen behältnissen mit ultraviolettem licht

Publications (3)

Publication Number Publication Date
BRPI0620280A2 BRPI0620280A2 (pt) 2013-03-12
BRPI0620280B1 BRPI0620280B1 (pt) 2016-06-28
BRPI0620280B8 true BRPI0620280B8 (pt) 2017-11-07

Family

ID=37946290

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0620280A BRPI0620280B8 (pt) 2005-12-23 2006-12-21 método de inativação de patógenos e / ou leucócitos em concentrados de plaquetas

Country Status (15)

Country Link
US (1) US8173066B2 (pt)
EP (1) EP1968652B1 (pt)
JP (1) JP5319298B2 (pt)
KR (1) KR101338511B1 (pt)
CN (1) CN101340936B (pt)
AT (1) ATE555815T1 (pt)
AU (1) AU2006332293B2 (pt)
BR (1) BRPI0620280B8 (pt)
CA (1) CA2634296C (pt)
DE (1) DE102005062410A1 (pt)
ES (1) ES2389778T3 (pt)
MX (1) MX2008008240A (pt)
NZ (1) NZ569429A (pt)
RU (1) RU2441669C2 (pt)
WO (1) WO2007076834A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3101221B2 (ja) 1997-01-23 2000-10-23 日鐵溶接工業株式会社 ２電極片面ガスシールドアーク溶接方法
JP3121597B2 (ja) 1999-10-20 2001-01-09 日鐵溶接工業株式会社 ２電極片面ガスシールドアーク溶接装置
DE102005062410A1 (de) 2005-12-23 2007-08-09 Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht
DE102005062634A1 (de) 2005-12-23 2007-06-28 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
EP1902740A1 (en) 2006-09-19 2008-03-26 Maco Pharma S.A. Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system
EP2008669A1 (en) 2007-06-22 2008-12-31 Maco Pharma S.A. Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process
FR2941866B1 (fr) 2009-02-09 2011-05-13 Maco Pharma Sa Procede pour modifier les proprietes d'un fluide par irradiation et systeme pour sa mise en oeuvre
US8883409B1 (en) 2013-12-08 2014-11-11 Hemalux LLC Method of reducing pathogens in whole blood by illuminating with ultraviolet light under low oxygen conditions
JP6559577B2 (ja) * 2016-01-06 2019-08-14 日機装株式会社 流体殺菌装置及び流体殺菌方法
EP3399986B1 (en) * 2016-01-07 2023-02-22 Cerus Corporation Systems and methods for preparation of platelets
RU167874U1 (ru) * 2016-08-03 2017-01-11 Государственное бюджетное учреждение здравоохранения города Москвы "Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы" Устройство для подготовки криоконсервированных тромбоцитов к трансфузии
US11020502B1 (en) 2020-05-01 2021-06-01 Uv Innovators, Llc Ultraviolet (UV) light emission device, and related methods of use, particularly suited for decontamination
CN111544296B (zh) * 2020-06-18 2024-03-12 四川省人民医院 一种血液制品光能保藏袋
FR3112985B1 (fr) 2020-08-03 2023-11-17 Maco Pharma Sa Appareil pour souder une poche
FR3133135B1 (fr) 2022-03-04 2026-01-30 Maco Pharma Sa Système à poches pour le traitement par irradiation électromagnétique d’un fluide biologique
FR3133134A1 (fr) 2022-03-04 2023-09-08 Maco Pharma Système à poches pour le traitement par irradiation électromagnétique d’un fluide biologique
FR3138040A1 (fr) 2022-07-21 2024-01-26 Maco Pharma Appareil et procédé pour irradier un fluide biologique

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2030200A (en) * 1934-03-30 1936-02-11 Rca Corp Ceramic object and method of making the same
US4469227A (en) * 1983-08-17 1984-09-04 Clifford Faust Package for cryogenically frozen liquids
US4586928A (en) * 1984-10-09 1986-05-06 Miles Laboratories, Inc. Pivoting frangible valve for plastic bags
US4952812A (en) * 1986-08-26 1990-08-28 Baxter International Inc. Irradiation of blood products
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
GB8807380D0 (en) 1988-03-29 1988-05-05 Gunn A Blood processing apparatus
US4952818A (en) * 1989-05-17 1990-08-28 International Business Machines Corporation Transmission line driver circuits
JPH05132424A (ja) * 1991-11-08 1993-05-28 Nissho Corp 赤血球を含む血液製剤の紫外線照射方法
JPH05131018A (ja) 1991-11-11 1993-05-28 Terumo Corp バツグ連結体およびその製造方法
US6420570B1 (en) * 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5625079A (en) * 1993-06-28 1997-04-29 Cerus Corporation Synthesizing psoralen compounds useful as intermediates
AU1172195A (en) * 1993-11-10 1995-05-29 Steritech, Inc. Device and method for photoactivation
EP1842561A1 (fr) * 1995-07-14 2007-10-10 CAF - DCF cvba - scrl Procédé et installation d'inactivation UV de virus dans des produits sanguins
DE29801590U1 (de) 1998-01-30 1998-04-16 Maco Pharma Int Gmbh Blutbeutelsystem zur Virusinaktivierung von Blut, Blutkomponenten und Plasma
EP1002512A3 (en) 1998-11-19 2001-01-24 Bracco International B.V. Flexible container for the containment and delivery of fluids
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6268120B1 (en) * 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US6576201B1 (en) 2000-01-28 2003-06-10 Baxter International Inc. Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation
US6596230B1 (en) 2000-01-28 2003-07-22 Baxter International Inc. Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation
RU2193893C2 (ru) * 2000-04-17 2002-12-10 Научно-технический центр "Лекбиотех" Способ стерилизации плазмы и препаратов из плазмы крови
AU2001296309A1 (en) 2000-09-27 2002-04-08 Gambro, Inc Inactivation of contaminants using photosensitizers and pulsed light
DE10056096A1 (de) * 2000-11-13 2002-06-13 Bayer Ag Vorrichtung zur Bestrahlung von Flüssigkeiten
US20020138066A1 (en) * 2001-03-23 2002-09-26 Gambro, Inc. Multiple compartment bag with openable closure assembly
US20030127603A1 (en) 2001-05-15 2003-07-10 Bernard Horowitz Apparatus for the inactivation of pathogens in protein-containing fluids and uses thereof
US20030064001A1 (en) * 2001-05-17 2003-04-03 Fries William M. System for the decontamination of fluid products using light
US20030228564A1 (en) * 2001-05-30 2003-12-11 Edrich Richard Alan Nitric oxide in a pathogen inactivation process
JP2005503870A (ja) * 2001-09-27 2005-02-10 ガンブロ、 インコーポレイテッド 体外血液処理に使用する高周波または電磁気情報装置および方法
DE10152159A1 (de) 2001-10-25 2003-05-15 Aventis Behring Gmbh Verfahren zur proteinschonenden Reinigung von kontaminierten biologischen Flüssigkeiten
WO2003063915A1 (en) 2002-02-01 2003-08-07 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
WO2003086479A1 (en) 2002-04-12 2003-10-23 Throwleigh Technologies, L.L.C. Methods and apparatus for decontaminating fluids
CA2484116C (en) * 2002-04-26 2010-08-03 Gambro, Inc. Apparatus and method for irradiating and mixing fluids in containers
US7207964B2 (en) * 2003-03-17 2007-04-24 Hemavation, Llc Apparatus and method for down-regulating immune system mediators in blood
US8296071B2 (en) * 2004-03-15 2012-10-23 Terumo Bct Biotechnologies, Llc Methods for uniformly treating biological samples with electromagnetic radiation
FR2887335B1 (fr) 2005-06-21 2007-08-10 Maco Pharma Sa Procede pour la determination d'une contamination pathogene dans un fluide contenant des plaquettes sanguines
DE102005062634A1 (de) 2005-12-23 2007-06-28 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
DE102005062410A1 (de) 2005-12-23 2007-08-09 Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht
EP1902740A1 (en) 2006-09-19 2008-03-26 Maco Pharma S.A. Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system
EP2008669A1 (en) * 2007-06-22 2008-12-31 Maco Pharma S.A. Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process

Also Published As

Publication number Publication date
US20090155121A1 (en) 2009-06-18
AU2006332293A1 (en) 2007-07-12
KR20080091157A (ko) 2008-10-09
RU2441669C2 (ru) 2012-02-10
US8173066B2 (en) 2012-05-08
ES2389778T3 (es) 2012-10-31
BRPI0620280A2 (pt) 2013-03-12
DE102005062410A1 (de) 2007-08-09
EP1968652A1 (de) 2008-09-17
HK1121975A1 (en) 2009-05-08
CN101340936B (zh) 2013-01-16
MX2008008240A (es) 2008-09-11
NZ569429A (en) 2011-09-30
ATE555815T1 (de) 2012-05-15
KR101338511B1 (ko) 2013-12-10
AU2006332293B2 (en) 2013-03-14
EP1968652B1 (de) 2012-05-02
WO2007076834A8 (de) 2007-10-04
RU2008129481A (ru) 2010-01-27
JP5319298B2 (ja) 2013-10-16
CN101340936A (zh) 2009-01-07
JP2009523710A (ja) 2009-06-25
BRPI0620280B1 (pt) 2016-06-28
CA2634296C (en) 2014-07-15
CA2634296A1 (en) 2007-07-12
WO2007076834A1 (de) 2007-07-12

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