BRPI0620723A2 - inibição de igf1r mediada por rnai para tratamento de angiogênese ocular - Google Patents

inibição de igf1r mediada por rnai para tratamento de angiogênese ocular Download PDF

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Publication number: BRPI0620723A2
Authority: BR; Brazil
Prior art keywords: nucleotides; mrna; seq; filament; rna
Prior art date: 2005-12-29

Application number

BRPI0620723-5A

Other languages

English (en)

Portuguese (pt)

Inventor

Jon E Chatterton

David P Bingaman

Original Assignee

Alcon Res Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-29

Filing date

2006-12-29

Publication date

2011-11-22

2006-12-29 Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd

2011-11-22 Publication of BRPI0620723A2 publication Critical patent/BRPI0620723A2/pt

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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
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Organic Chemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
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Wood Science & Technology (AREA)
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Biotechnology (AREA)
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Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Cardiology (AREA)
Emergency Medicine (AREA)
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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0620723-5A 2005-12-29 2006-12-29 inibição de igf1r mediada por rnai para tratamento de angiogênese ocular BRPI0620723A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US75479605P	2005-12-29	2005-12-29
US60/754,796		2005-12-29
PCT/US2006/062750 WO2007076548A2 (en)	2005-12-29	2006-12-29	RNAi-MEDIATED INHIBITION OF IGFlR FOR TREATMENT OF OCULAR ANGIOGENESIS

Publications (1)

Publication Number	Publication Date
BRPI0620723A2 true BRPI0620723A2 (pt)	2011-11-22

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ID=38218895

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0620723-5A BRPI0620723A2 (pt)	2005-12-29	2006-12-29	inibição de igf1r mediada por rnai para tratamento de angiogênese ocular

Country Status (16)

Country	Link
US (2)	US20070275922A1 (pl)
EP (2)	EP1966368B1 (pl)
JP (2)	JP2009522312A (pl)
KR (1)	KR20080082655A (pl)
CN (1)	CN101326282A (pl)
AU (1)	AU2006330435C1 (pl)
BR (1)	BRPI0620723A2 (pl)
CA (1)	CA2632690C (pl)
CY (1)	CY1113098T1 (pl)
DK (1)	DK1966368T3 (pl)
ES (1)	ES2392185T3 (pl)
PL (1)	PL1966368T3 (pl)
PT (1)	PT1966368E (pl)
RU (1)	RU2008130901A (pl)
WO (1)	WO2007076548A2 (pl)
ZA (1)	ZA200805601B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008137066A1 (en) *	2007-05-02	2008-11-13	The Board Of Regents Of The University Of Oklahoma	Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases
WO2010042751A2 (en) *	2008-10-08	2010-04-15	Chimeros Inc.	Chimeric therapeutics, compositions, and methods for using same
CN102727513B (zh) *	2011-04-15	2014-07-09	百奥迈科生物技术有限公司	靶向于组织因子基因的小核酸及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000078341A1 (en) *	1999-06-21	2000-12-28	Murdoch Childrens Research Institute	A method for the prophylaxis and/or treatment of medical disorders
US20050164966A1 (en) *	2001-05-18	2005-07-28	Sirna Therapeutics, Inc.	RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)
EP1432724A4 (en) *	2002-02-20	2006-02-01	Sirna Therapeutics Inc	INTERFERENCE MEDIATION INHIBITION OF GENE RNA FROM MAP KINASE
GB0212303D0 (en) *	2002-05-28	2002-07-10	Isis Innovation	Molecular targetting of IGF-1 receptor
US20040086860A1 (en) *	2002-10-04	2004-05-06	Muhammad Sohail	Methods of producing RNAs of defined length and sequence
CA2515484C (en) *	2003-02-11	2011-09-20	Antisense Therapeutics Ltd	Modulation of insulin like growth factor i receptor expression
US7803781B2 (en) *	2003-02-28	2010-09-28	Isis Pharmaceuticals, Inc.	Modulation of growth hormone receptor expression and insulin-like growth factor expression
ATE514434T1 (de) *	2004-02-25	2011-07-15	Dana Farber Cancer Inst Inc	Hemmer des insulinartigen wachstumsfaktor- rezeptors-1 zur hemmung von tumorzellwachstum

2006
- 2006-12-29 DK DK06840364.1T patent/DK1966368T3/da active
- 2006-12-29 JP JP2008548873A patent/JP2009522312A/ja active Pending
- 2006-12-29 CN CNA2006800464673A patent/CN101326282A/zh active Pending
- 2006-12-29 BR BRPI0620723-5A patent/BRPI0620723A2/pt not_active Application Discontinuation
- 2006-12-29 AU AU2006330435A patent/AU2006330435C1/en not_active Ceased
- 2006-12-29 PT PT06840364T patent/PT1966368E/pt unknown
- 2006-12-29 WO PCT/US2006/062750 patent/WO2007076548A2/en not_active Ceased
- 2006-12-29 PL PL06840364T patent/PL1966368T3/pl unknown
- 2006-12-29 KR KR1020087015418A patent/KR20080082655A/ko not_active Ceased
- 2006-12-29 RU RU2008130901/13A patent/RU2008130901A/ru not_active Application Discontinuation
- 2006-12-29 EP EP06840364A patent/EP1966368B1/en not_active Not-in-force
- 2006-12-29 US US11/617,899 patent/US20070275922A1/en not_active Abandoned
- 2006-12-29 CA CA2632690A patent/CA2632690C/en not_active Expired - Fee Related
- 2006-12-29 ES ES06840364T patent/ES2392185T3/es active Active
- 2006-12-29 EP EP12174878A patent/EP2527443A3/en not_active Withdrawn
2008
- 2008-06-26 ZA ZA2008/05601A patent/ZA200805601B/en unknown
2012
- 2012-09-07 CY CY20121100808T patent/CY1113098T1/el unknown
- 2012-09-25 JP JP2012210913A patent/JP2012254095A/ja active Pending
2014
- 2014-03-28 US US14/229,055 patent/US20140364480A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20140364480A1 (en)	2014-12-11
ES2392185T3 (es)	2012-12-05
AU2006330435C1 (en)	2014-03-06
EP1966368A4 (en)	2010-10-06
HK1117873A1 (en)	2009-01-23
CY1113098T1 (el)	2016-04-13
JP2009522312A (ja)	2009-06-11
WO2007076548A2 (en)	2007-07-05
WO2007076548A3 (en)	2008-04-17
PT1966368E (pt)	2012-11-02
AU2006330435B2 (en)	2013-08-22
JP2012254095A (ja)	2012-12-27
DK1966368T3 (da)	2012-09-17
ZA200805601B (en)	2009-12-30
US20070275922A1 (en)	2007-11-29
CN101326282A (zh)	2008-12-17
EP2527443A3 (en)	2013-02-20
EP1966368A2 (en)	2008-09-10
CA2632690A1 (en)	2007-07-05
CA2632690C (en)	2015-01-13
PL1966368T3 (pl)	2013-03-29
EP2527443A2 (en)	2012-11-28
KR20080082655A (ko)	2008-09-11
EP1966368B1 (en)	2012-08-22
RU2008130901A (ru)	2010-04-10
AU2006330435A1 (en)	2007-07-05

Legal Events

Date	Code	Title	Description
2012-04-10	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2015-06-30	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2015-11-24	B15K	Others concerning applications: alteration of classification	Free format text: A CLASSIFICACAO ANTERIOR ERA: C12N 15/113 Ipc: C12N 15/113 (2010.01), A61K 31/7105 (2006.01), A61
2016-08-02	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2016-11-16	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2017-07-04	B09B	Patent application refused [chapter 9.2 patent gazette]
2018-05-29	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL

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BRPI0621264A2 (pt)	2011-12-06	inibição mediada por rnai de rho quinase para o tratamento de distúrbios oculares
US20110190376A1 (en)	2011-08-04	RNAi-RELATED INHIBITION OF TNFa SIGNALING PATHWAY FOR TREATMENT OF MACULAR EDEMA
US20140364480A1 (en)	2014-12-11	RNAi-MEDIATED INHIBITION OF IGF1R FOR TREATMENT OF OCULAR ANGIOGENESIS
HK1117873B (en)	2012-12-21	Rnai-mediated inhibition of igf-1r for treatment of ocular angiogenesis
MX2008006910A (es)	2008-09-02	Inhibicion mediada por rnai de igfir para tratamiento de angiogenesis ocular
MX2008007106A (en)	2008-09-26	Rnai-mediated inhibition of hif1a for treatment of ocular angiogenesis