BRPI0703658A8 - n-benzyl derivatives - (- 3-o-acetyl) -piperidines, pharmaceutical compositions containing them, and processes for their preparation - Google Patents

n-benzyl derivatives - (- 3-o-acetyl) -piperidines, pharmaceutical compositions containing them, and processes for their preparation

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Publication number
BRPI0703658A8
BRPI0703658A8 BRPI0703658A BRPI0703658A BRPI0703658A8 BR PI0703658 A8 BRPI0703658 A8 BR PI0703658A8 BR PI0703658 A BRPI0703658 A BR PI0703658A BR PI0703658 A BRPI0703658 A BR PI0703658A BR PI0703658 A8 BRPI0703658 A8 BR PI0703658A8
Authority
BR
Brazil
Prior art keywords
acetyl
preparation
pharmaceutical compositions
compositions containing
processes
Prior art date
Application number
BRPI0703658A
Other languages
Portuguese (pt)
Inventor
Viegas Junior Cláudio
Paranho Veloso Marcia
Santos Rocha Mônica
G Castro Newton
Da Silva Bolzani Vanderlan
Original Assignee
Fund Amparo Pesquisa Estado Minas Gerais Fapemig
Univ Federal De Alfenas Unifal Mg
Univ Federal Do Rio De Janeiro Ufrj
Univ Estadual Paulista Julio De Mesquita Filho Unesp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fund Amparo Pesquisa Estado Minas Gerais Fapemig, Univ Federal De Alfenas Unifal Mg, Univ Federal Do Rio De Janeiro Ufrj, Univ Estadual Paulista Julio De Mesquita Filho Unesp filed Critical Fund Amparo Pesquisa Estado Minas Gerais Fapemig
Priority to BRPI0703658A priority Critical patent/BRPI0703658B8/en
Publication of BRPI0703658A2 publication Critical patent/BRPI0703658A2/en
Publication of BRPI0703658A8 publication Critical patent/BRPI0703658A8/en
Publication of BRPI0703658B1 publication Critical patent/BRPI0703658B1/en
Publication of BRPI0703658B8 publication Critical patent/BRPI0703658B8/en

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  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

derivados n-benzil-(-3-acetil)piperidínicos, composições farmacêuticas contendos os mesmos, e processos para sua preparação. a presente invenção proporciona derivados piperidínicos, em especial a derivados 3-o-acetil-piperidinil-n-benzil-subsitutídos de fórmula geral (i) e/ou (ii). em especial, tais compostos apresentam atividade inibidora de acetilcolinesterase no sistema nervoso central em ensaios farmacológicos, podendo ser úteis no tratamento de doenças como a doença de alzheimer. também são revelados: um processo para a preparação destes compostos; e composições farmacêuticas contendo os mesmos.n-benzyl - (- 3-acetyl) piperidine derivatives, pharmaceutical compositions containing the same, and processes for their preparation. the present invention provides piperidine derivatives, in particular 3-o-acetyl-piperidinyl-n-benzyl-substituted derivatives of the general formula (i) and / or (ii). in particular, such compounds have acetylcholinesterase inhibitory activity in the central nervous system in pharmacological tests, and may be useful in the treatment of diseases such as alzheimer's disease. also disclosed: a process for the preparation of these compounds; and pharmaceutical compositions containing them.

BRPI0703658A 2007-10-03 2007-10-03 n-benzyl-(-3-o-acetyl)-piperidine derivatives, pharmaceutical compositions containing them, and processes for their preparation BRPI0703658B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0703658A BRPI0703658B8 (en) 2007-10-03 2007-10-03 n-benzyl-(-3-o-acetyl)-piperidine derivatives, pharmaceutical compositions containing them, and processes for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0703658A BRPI0703658B8 (en) 2007-10-03 2007-10-03 n-benzyl-(-3-o-acetyl)-piperidine derivatives, pharmaceutical compositions containing them, and processes for their preparation

Publications (4)

Publication Number Publication Date
BRPI0703658A2 BRPI0703658A2 (en) 2010-06-08
BRPI0703658A8 true BRPI0703658A8 (en) 2021-03-16
BRPI0703658B1 BRPI0703658B1 (en) 2021-03-30
BRPI0703658B8 BRPI0703658B8 (en) 2021-05-25

Family

ID=42234003

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0703658A BRPI0703658B8 (en) 2007-10-03 2007-10-03 n-benzyl-(-3-o-acetyl)-piperidine derivatives, pharmaceutical compositions containing them, and processes for their preparation

Country Status (1)

Country Link
BR (1) BRPI0703658B8 (en)

Also Published As

Publication number Publication date
BRPI0703658B1 (en) 2021-03-30
BRPI0703658B8 (en) 2021-05-25
BRPI0703658A2 (en) 2010-06-08

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Legal Events

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B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: PARA QUE A SOLICITACAO REQUERIDA NA PETICAO NO 020080076912/RJ DE 21/05/2008 SEJA ATENDIDA, APRESENTE DOCUMENTO QUE COMPROVE TAL PEDIDO, UMA VEZ QUE O DOCUMENTO APRESENTADO NA REFERENTE PETICAO NAO FOI DATADO E HA UMA DIVERGENCIA, NO QUE DIZ RESPEITO AO TITULO DO PROCESSO. RESSALTA-SE QUE DEVE CONSTAR A CIENCIA DOS DEMAIS DEPOSITANTES, NO QUE SE REFERE A INCLUSAO DO DEPOSITANTE. SOLICITA-SE AINDA, A REGULARIZACAO DAS PROCURACOES, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO EM SUA FORMA AUTENTICADA; OU SEGUNDO PARECER DA PROCURADORIA MEMO/INPI/PROC/NO 074/93, DEVE CONSTAR UMA DECLARACAO DE VERACIDADE, A QUAL DEVE SER ASSINADA POR UMA PES

B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: PARA QUE A SOLICITACAO REQUERIDA NA PETICAO NO 020080076912/RJ DE 21/05/2008 SEJA ATENDIDA, APRESENTE DOCUMENTO QUE COMPROVE TAL PEDIDO, UMA VEZ QUE O DOCUMENTO APRESENTADO NA REFERENTE PETICAO NAO FOI DATADO E HA UMA DIVERGENCIA, NO QUE DIZ RESPEITO AO TITULO DO PROCESSO. RESSALTA-SE QUE DEVE CONSTAR A CIENCIA DOS DEMAIS DEPOSITANTES, NO QUE SE REFERE A INCLUSAO DO DEPOSITANTE. SOLICITA-SE AINDA, A REGULARIZACAO DAS PROCURACOES, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO EM SUA FORMA AUTENTICADA; OU SEGUNDO PARECER DA PROCURADORIA MEMO/INPI/PROC/NO 074/93, DEVE CONSTAR UMA DECLARACAO DE VERACIDADE, A QUAL DEVE SER ASSINADA POR UMA PES

B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 3A E 4A ANUIDADES.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE A DESPACHO 8.6 NA RPI 2167 DE 17/07/2012.

B03H Publication of an application: rectification [chapter 3.8 patent gazette]

Free format text: REFERENTE A RPI 2057 DE 08/06/2010, QUANTO AOS ITENS (71 E 74).

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B03H Publication of an application: rectification [chapter 3.8 patent gazette]

Free format text: REFERENTE A RPI NO 2057 QUANTO AOS ITENS (71) E (72).

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/03/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/10/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF