BRPI0709412A8 - método de produção de uma bandagem hemostática utilizando um objeto rotativo - Google Patents

método de produção de uma bandagem hemostática utilizando um objeto rotativo

Info

Publication number
BRPI0709412A8
BRPI0709412A8 BRPI0709412A BRPI0709412A BRPI0709412A8 BR PI0709412 A8 BRPI0709412 A8 BR PI0709412A8 BR PI0709412 A BRPI0709412 A BR PI0709412A BR PI0709412 A BRPI0709412 A BR PI0709412A BR PI0709412 A8 BRPI0709412 A8 BR PI0709412A8
Authority
BR
Brazil
Prior art keywords
producing
collector
hemostatic bandage
fibers
rotating disc
Prior art date
Application number
BRPI0709412A
Other languages
English (en)
Inventor
Larsen Gustavo
Velarde-Ortiz Raffet
Spretz Ruben
Original Assignee
Larsen Gustavo
Raffet Velardez Ortiz
Spretz Ruben
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Larsen Gustavo, Raffet Velardez Ortiz, Spretz Ruben filed Critical Larsen Gustavo
Publication of BRPI0709412A2 publication Critical patent/BRPI0709412A2/pt
Publication of BRPI0709412A8 publication Critical patent/BRPI0709412A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D10/00—Physical treatment of artificial filaments or the like during manufacture, i.e. during a continuous production process before the filaments have been collected
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D01D5/0092—Electro-spinning characterised by the electro-spinning apparatus characterised by the electrical field, e.g. combined with a magnetic fields, using biased or alternating fields
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/18—Formation of filaments, threads, or the like by means of rotating spinnerets
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Textile Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)

Abstract

método de produção de uma bandagem hemostatica utilizando um objeto rotativo trata-se de um método de manufaturar uma bandagem hemostática fibrosa resistente e flexível ao produzir fibras que expõem ao máximo a área de superfície por unidade de peso de ingredientes ativos como um meio para ajudar no processode formação de coágulo e como um meio para minimizar o desperdício de ingredientes ativos. o método utiliza um objeto rotativo para fazer girar um precursor de fibra biocompativel líquido, o qual é adicionado em seu centro. asfibras formadas então são depositadas em um coletor localizado a uma distância do objeto rotativo tal que cria uma camada de fibra no coletor. uma diferença de potencial elétrico é mantida entre o disco rotativo e o coletor. então, uma espécie de pró-coagulação líquido é introduzido no centro do disco rotativo de maneira tal que faz girar o disco rotativo e reveste as fibras.
BRPI0709412A 2006-03-28 2007-01-13 método de produção de uma bandagem hemostática utilizando um objeto rotativo BRPI0709412A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74386606P 2006-03-28 2006-03-28
US60/743,866 2006-03-28
PCT/IB2007/050107 WO2007110783A2 (en) 2006-03-28 2007-01-13 Method of manufacturing fibrous hemostatic bandages

Publications (2)

Publication Number Publication Date
BRPI0709412A2 BRPI0709412A2 (pt) 2011-07-12
BRPI0709412A8 true BRPI0709412A8 (pt) 2019-01-02

Family

ID=38541513

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0709412A BRPI0709412A8 (pt) 2006-03-28 2007-01-13 método de produção de uma bandagem hemostática utilizando um objeto rotativo

Country Status (6)

Country Link
US (2) US20090136651A1 (pt)
EP (1) EP1998798B1 (pt)
BR (1) BRPI0709412A8 (pt)
ES (1) ES2405945T3 (pt)
PL (1) PL1998798T3 (pt)
WO (1) WO2007110783A2 (pt)

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Also Published As

Publication number Publication date
US20120171355A1 (en) 2012-07-05
BRPI0709412A2 (pt) 2011-07-12
WO2007110783A2 (en) 2007-10-04
US20090136651A1 (en) 2009-05-28
EP1998798B1 (en) 2013-02-27
EP1998798A4 (en) 2010-04-14
ES2405945T3 (es) 2013-06-04
WO2007110783A3 (en) 2009-04-23
US8257778B2 (en) 2012-09-04
EP1998798A2 (en) 2008-12-10
PL1998798T3 (pl) 2013-08-30

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