BRPI0709412A8 - método de produção de uma bandagem hemostática utilizando um objeto rotativo - Google Patents

método de produção de uma bandagem hemostática utilizando um objeto rotativo

Info

Publication number
BRPI0709412A8
BRPI0709412A8 BRPI0709412A BRPI0709412A BRPI0709412A8 BR PI0709412 A8 BRPI0709412 A8 BR PI0709412A8 BR PI0709412 A BRPI0709412 A BR PI0709412A BR PI0709412 A BRPI0709412 A BR PI0709412A BR PI0709412 A8 BRPI0709412 A8 BR PI0709412A8
Authority
BR
Brazil
Prior art keywords
producing
collector
hemostatic bandage
fibers
rotating disc
Prior art date
Application number
BRPI0709412A
Other languages
English (en)
Inventor
Larsen Gustavo
Velarde-Ortiz Raffet
Spretz Ruben
Original Assignee
Larsen Gustavo
Raffet Velardez Ortiz
Spretz Ruben
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Larsen Gustavo, Raffet Velardez Ortiz, Spretz Ruben filed Critical Larsen Gustavo
Publication of BRPI0709412A2 publication Critical patent/BRPI0709412A2/pt
Publication of BRPI0709412A8 publication Critical patent/BRPI0709412A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D10/00—Physical treatment of artificial filaments or the like during manufacture, i.e. during a continuous production process before the filaments have been collected
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D01D5/0092—Electro-spinning characterised by the electro-spinning apparatus characterised by the electrical field, e.g. combined with a magnetic fields, using biased or alternating fields
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/18—Formation of filaments, threads, or the like by means of rotating spinnerets
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Textile Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Mechanical Engineering (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)

Abstract

método de produção de uma bandagem hemostatica utilizando um objeto rotativo trata-se de um método de manufaturar uma bandagem hemostática fibrosa resistente e flexível ao produzir fibras que expõem ao máximo a área de superfície por unidade de peso de ingredientes ativos como um meio para ajudar no processode formação de coágulo e como um meio para minimizar o desperdício de ingredientes ativos. o método utiliza um objeto rotativo para fazer girar um precursor de fibra biocompativel líquido, o qual é adicionado em seu centro. asfibras formadas então são depositadas em um coletor localizado a uma distância do objeto rotativo tal que cria uma camada de fibra no coletor. uma diferença de potencial elétrico é mantida entre o disco rotativo e o coletor. então, uma espécie de pró-coagulação líquido é introduzido no centro do disco rotativo de maneira tal que faz girar o disco rotativo e reveste as fibras.
BRPI0709412A 2006-03-28 2007-01-13 método de produção de uma bandagem hemostática utilizando um objeto rotativo BRPI0709412A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74386606P 2006-03-28 2006-03-28
US60/743,866 2006-03-28
PCT/IB2007/050107 WO2007110783A2 (en) 2006-03-28 2007-01-13 Method of manufacturing fibrous hemostatic bandages

Publications (2)

Publication Number Publication Date
BRPI0709412A2 BRPI0709412A2 (pt) 2011-07-12
BRPI0709412A8 true BRPI0709412A8 (pt) 2019-01-02

Family

ID=38541513

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0709412A BRPI0709412A8 (pt) 2006-03-28 2007-01-13 método de produção de uma bandagem hemostática utilizando um objeto rotativo

Country Status (6)

Country Link
US (2) US20090136651A1 (pt)
EP (1) EP1998798B1 (pt)
BR (1) BRPI0709412A8 (pt)
ES (1) ES2405945T3 (pt)
PL (1) PL1998798T3 (pt)
WO (1) WO2007110783A2 (pt)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8303874B2 (en) 2006-03-28 2012-11-06 E I Du Pont De Nemours And Company Solution spun fiber process
US8297959B2 (en) 2006-05-03 2012-10-30 Terapia Celular, Ln, Inc. Systems for producing multilayered particles, fibers and sprays and methods for administering the same
WO2007135492A2 (en) * 2006-05-18 2007-11-29 Gustavo Larsen Methods for making a multicomponent hemostatic dressing
TW200848561A (en) * 2006-12-22 2008-12-16 Body Organ Biomedical Corp Device for manufacturing fibrils
US8277711B2 (en) 2007-03-29 2012-10-02 E I Du Pont De Nemours And Company Production of nanofibers by melt spinning
DE102007044648B4 (de) * 2007-09-18 2020-11-26 Carl Freudenberg Kg Bioresorbierbarer Gelatinevliesstoff
KR20100088141A (ko) * 2007-10-23 2010-08-06 피피지 인더스트리즈 오하이오 인코포레이티드 전기-기계적 방사에 의한 섬유의 제조
US9834865B2 (en) * 2007-12-17 2017-12-05 E I Du Pont De Nemours And Company Centrifugal solution spun nanofiber process
WO2010083530A2 (en) 2009-01-16 2010-07-22 Zeus Industrial Products, Inc. Electrospinning of ptfe with high viscosity materials
US20130268062A1 (en) 2012-04-05 2013-10-10 Zeus Industrial Products, Inc. Composite prosthetic devices
IN2012DN00525A (pt) 2009-08-07 2015-06-05 Zeus Ind Products Inc
CN102782196A (zh) 2010-10-14 2012-11-14 宙斯工业产品股份有限公司 抗微生物基材
EP2447397A1 (de) * 2010-10-29 2012-05-02 Carl Freudenberg KG Vliesstoffe aus synthetischen Polymeren sowie Rotationsspinnverfahren zur Herstellung derselben
JP6203639B2 (ja) 2011-01-28 2017-09-27 メリット・メディカル・システムズ・インコーポレイテッドＭｅｒｉｔ Ｍｅｄｉｃａｌ Ｓｙｓｔｅｍｓ，Ｉｎｃ． 電界紡糸されたｐｔｆｅでコーティングされたステントおよび使用方法
WO2013109528A1 (en) 2012-01-16 2013-07-25 Merit Medical Systems, Inc. Rotational spun material covered medical appliances and methods of manufacture
AR091031A1 (es) * 2012-05-14 2014-12-30 Teijin Ltd Producto en planchas y material hemostatico
US9527257B2 (en) * 2012-08-06 2016-12-27 Clarcor Inc. Devices and methods for the production of microfibers and nanofibers having one or more additives
EP2885071A4 (en) * 2012-08-14 2016-06-22 Evan Koslow METHOD FOR TREATING UNDERGROUND FORMATIONS USING MIXED RETAINING AGENTS
US10507268B2 (en) 2012-09-19 2019-12-17 Merit Medical Systems, Inc. Electrospun material covered medical appliances and methods of manufacture
US9198999B2 (en) 2012-09-21 2015-12-01 Merit Medical Systems, Inc. Drug-eluting rotational spun coatings and methods of use
DE102012224379A1 (de) * 2012-12-27 2014-07-03 Aesculap Ag Faserprodukt und Verfahren zu seiner Herstellung
CN103114342B (zh) * 2013-03-05 2016-01-20 青岛大学 一种简易高效制备定向纳米纤维的静电纺丝装置
WO2014159399A1 (en) 2013-03-13 2014-10-02 Merit Medical Systems, Inc. Methods, systems, and apparatuses for manufacturing rotational spun appliances
CN104884694B (zh) 2013-03-13 2018-09-11 麦瑞通医疗设备有限公司 连续沉积的纤维材料以及相关联的装置和方法
WO2014169239A1 (en) * 2013-04-12 2014-10-16 Donaldson Company, Inc. Centrifugal electrospinning process
EP3071397B1 (en) * 2013-11-20 2024-04-17 Trusscore Inc. Method for forming composites
DE102014202578A1 (de) * 2014-02-12 2015-08-13 Aesculap Ag Medizinisches Produkt und Verfahren zu seiner Herstellung
US20150345049A1 (en) * 2014-05-28 2015-12-03 University Of Georgia Research Foundation, Inc. Magnetospinning apparatus for low-magnetic materials and methods of use
CN104088024B (zh) * 2014-07-10 2017-02-01 北京化工大学 一种离心熔体静电纺丝装置
WO2016138221A1 (en) 2015-02-26 2016-09-01 Merit Medical Systems, Inc. Layered medical appliances and methods
US11155959B2 (en) 2017-06-20 2021-10-26 Lintec Of America, Inc. Densifying a nanofiber sheet using heat and force
CN107456609A (zh) * 2017-07-17 2017-12-12 浙江大学 方向性生物微纳米纤维支架快速制备装置及微纳米纤维支架的制备方法
WO2019089856A1 (en) 2017-10-31 2019-05-09 InMEDBio, LLC Absorbent, breathable and pathogen blocking/killing wound care dressing and fabrication thereof
KR101876196B1 (ko) * 2017-11-03 2018-07-09 세원셀론텍(주) 콜라겐을 이용하여 제조된 의료용 재료 및 그 제조방법
CN110257929B (zh) * 2019-06-26 2022-04-19 广东工业大学 一种离心静电纺丝设备
WO2022183215A1 (en) 2021-02-26 2022-09-01 Merit Medical Systems, Inc. Fibrous constructs with therapeutic material particles
CN119431191A (zh) * 2023-07-28 2025-02-14 中国科学院长春应用化学研究所 一种促凝血化合物及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5940054B2 (ja) * 1978-08-29 1984-09-27 株式会社佐藤技術研究所 融体から特定サイズの球形粒子を製造する方法
US4290993A (en) * 1980-01-10 1981-09-22 Battelle Development Corp. Method and apparatus for making nodule filament fibers
US4613076A (en) * 1984-02-15 1986-09-23 General Electric Company Apparatus and method for forming fine liquid metal droplets
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer
US5522879A (en) * 1991-11-12 1996-06-04 Ethicon, Inc. Piezoelectric biomedical device
US5468529A (en) * 1992-08-28 1995-11-21 Korea Institute Of Science And Technology Magnetic filter material comprising a self-bonding nonwoven fabric of continuous thermoplastic fibers and magnetic particulate within the fibers
US20020090725A1 (en) * 2000-11-17 2002-07-11 Simpson David G. Electroprocessed collagen
US20020042128A1 (en) * 2000-09-01 2002-04-11 Bowlin Gary L. Electroprocessed fibrin-based matrices and tissues
CA2379909C (en) * 1999-08-06 2011-01-04 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
WO2001051690A1 (en) * 2000-01-06 2001-07-19 Drexel University Electrospinning ultrafine conductive polymeric fibers
US6716274B2 (en) * 2000-09-05 2004-04-06 Donaldson Company, Inc. Air filter assembly for filtering an air stream to remove particulate matter entrained in the stream
CN1472373A (zh) * 2003-03-28 2004-02-04 中国科学院长春应用化学研究所 旋碟纺丝法及纺丝装置
EP1718147B1 (en) * 2004-02-23 2012-03-28 Loma Linda University Medical Center Hemostatic agent for topical and internal use
US7134857B2 (en) * 2004-04-08 2006-11-14 Research Triangle Institute Electrospinning of fibers using a rotatable spray head
US8481074B2 (en) * 2004-07-16 2013-07-09 Poly-Med, Inc. Hemostatic microfibrous constructs
WO2007135492A2 (en) 2006-05-18 2007-11-29 Gustavo Larsen Methods for making a multicomponent hemostatic dressing
SE530751C2 (sv) * 2007-02-20 2008-09-02 Ifp Res Ab Anordning för framställning av nanofiber
DE102007027014A1 (de) * 2007-06-08 2008-12-18 Rainer Busch Vorrichtung zur Herstellung von Nano- und Microfasern durch elektrostatisches Spinnen einer durch Zentrifugalkräften in radialer Richtung aufgeschichteten Polymerlösung

Also Published As

Publication number Publication date
PL1998798T3 (pl) 2013-08-30
US20090136651A1 (en) 2009-05-28
EP1998798A4 (en) 2010-04-14
BRPI0709412A2 (pt) 2011-07-12
WO2007110783A3 (en) 2009-04-23
ES2405945T3 (es) 2013-06-04
EP1998798A2 (en) 2008-12-10
US8257778B2 (en) 2012-09-04
US20120171355A1 (en) 2012-07-05
EP1998798B1 (en) 2013-02-27
WO2007110783A2 (en) 2007-10-04

Similar Documents

Publication Publication Date Title
WO2007110783A3 (en) Method of manufacturing fibrous hemostatic bandages
Zhao et al. Janus membrane with intrafibrillarly strontium-apatite-mineralized collagen for guided bone regeneration
Bai et al. Processes of electrospun polyvinylidene fluoride-based nanofibers, their piezoelectric properties, and several fantastic applications
Si et al. Bioinspired Janus all-natural electrospinning membranes with directional water transport as ecofriendly dry facial masks
Zhang et al. Fabrication, property and application of calcium alginate fiber: A review
Gong et al. Polydopamine-mediated immunomodulatory patch for diabetic periodontal tissue regeneration assisted by metformin-ZIF system
Zhang et al. Polylactic acid nanopillar array-driven osteogenic differentiation of human adipose-derived stem cells determined by pillar diameter
Huang et al. Water-based black phosphorus hybrid nanosheets as a moldable platform for wound healing applications
Zhou et al. Collagen functionalized with graphene oxide enhanced biomimetic mineralization and in situ bone defect repair
Robles et al. Advances in electrospun poly (ε-caprolactone)-based nanofibrous scaffolds for tissue engineering
Ghorbani et al. Decoration of electrical conductive polyurethane‐polyaniline/polyvinyl alcohol matrixes with mussel‐inspired polydopamine for bone tissue engineering
Jing et al. Roles of electrical stimulation in promoting osteogenic differentiation of BMSCs on conductive fibers
JP2009061109A5 (pt)
Li et al. Continuous manufacturing of bioinspired bone‐periosteum integrated scaffold to promote bone regeneration
Nassar et al. Effect of phytic acid used as etchant on bond strength, smear layer, and pulpal cells
BR112015022040A2 (pt) substrato de lenço dispersível em água
EP4056144A3 (en) Dental articles, methods, and kits including a compressible material
AR080801A1 (es) Metodo para hacer un revestimiento y un panel acustico revestido utilizando fibras degradadas
López-González et al. Modifications in gene expression in the process of osteoblastic differentiation of multipotent bone marrow-derived human mesenchymal stem cells induced by a novel osteoinductive porous medical-grade 3D-printed poly (ε-caprolactone)/β-tricalcium phosphate composite
MX345705B (es) Material flexible altamente absorbente.
CN103191463B (zh) 一种壳聚糖纤维/生物活性玻璃三维有序多孔支架材料的制备方法
RU2011118120A (ru) Облицованное матом цементирующее изделие и способ его получения
KR20110119684A (ko) 무기계 섬유 구조체 및 그 제조 방법
EA200801709A1 (ru) Изделие для чистки и/или ухода за кожей и способ его производства
CN103637883A (zh) 一种用于卫生用品的吸水芯体及其生产工艺

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements