BRPI0716409A2 - beta-interferona recombinante com atividade biolàgica aumentada - Google Patents

beta-interferona recombinante com atividade biolàgica aumentada

Info

Publication number
BRPI0716409A2
BRPI0716409A2 BRPI0716409-2A2A BRPI0716409A BRPI0716409A2 BR PI0716409 A2 BRPI0716409 A2 BR PI0716409A2 BR PI0716409 A BRPI0716409 A BR PI0716409A BR PI0716409 A2 BRPI0716409 A2 BR PI0716409A2
Authority
BR
Brazil
Prior art keywords
biological activity
increased biological
beta interferon
recombinant beta
recombinant
Prior art date
Application number
BRPI0716409-2A2A
Other languages
English (en)
Inventor
Deborah Johnson-Jackson
Kenji Furuya
Isabel Zaror
Douglas Larson
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0716409A2 publication Critical patent/BRPI0716409A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0716409-2A2A 2006-08-08 2007-07-24 beta-interferona recombinante com atividade biolàgica aumentada BRPI0716409A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83654106P 2006-08-08 2006-08-08
PCT/US2007/016722 WO2008020968A2 (en) 2006-08-08 2007-07-24 Recombinant interferon-beta with enhanced biological activity

Publications (1)

Publication Number Publication Date
BRPI0716409A2 true BRPI0716409A2 (pt) 2013-09-24

Family

ID=38857937

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0716409-2A2A BRPI0716409A2 (pt) 2006-08-08 2007-07-24 beta-interferona recombinante com atividade biolàgica aumentada

Country Status (11)

Country Link
US (1) US20090311216A1 (pt)
EP (1) EP2059528A2 (pt)
JP (1) JP2010500024A (pt)
KR (1) KR20090047452A (pt)
CN (1) CN101506232A (pt)
AU (1) AU2007284964A1 (pt)
BR (1) BRPI0716409A2 (pt)
CA (1) CA2658715A1 (pt)
MX (1) MX2009001348A (pt)
RU (1) RU2009107894A (pt)
WO (1) WO2008020968A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3126379B1 (en) * 2014-04-04 2019-05-22 Ares Trading SA Novel ifn beta protein analogs
CN107099569B (zh) * 2017-06-30 2021-05-07 北京生物制品研究所有限责任公司 一种规模化发酵生产重组人干扰素β1b蛋白的方法
RU2739261C1 (ru) * 2019-12-31 2020-12-22 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Способ количественного определения антипролиферативной активности интерферона-бета человека
WO2025024775A1 (en) * 2023-07-26 2025-01-30 Epivax, Inc. Modified interferon-beta-1 having reduced immunogenicity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK2942002A3 (en) * 1999-08-27 2002-08-06 Maxygen Aps A conjugate exhibiting interferon beta, a nucleotide sequence, an expressing vector, a host cell containing such a nucleotide sequence, method for the preparation thereof, pharmaceutical composition containing the same and its use
BR0207576A (pt) * 2001-02-27 2004-04-27 Maxygen Aps Variante glicosilada de um polipeptìdeo de interferon beta precursor (ifnb), processos de aumentar a glicosilação in vivo de uma molécula de ifnb precursora, de produzir uma molécula de ifnb glicosilada, para preparar uma variante conjugada e de tratar um mamìfero com esclerose múltiplam composição farmacêutica, molécula de ifnb variante, sequência de nucleotìdeo, vetor de expressão, célula hospedeira de glicosilação conjugado, e, uso de um conjugado
ATE415421T1 (de) * 2004-11-10 2008-12-15 Novartis Vaccines & Diagnostic Deamidiertes interferon-beta

Also Published As

Publication number Publication date
WO2008020968A3 (en) 2008-05-29
JP2010500024A (ja) 2010-01-07
CA2658715A1 (en) 2008-02-21
AU2007284964A1 (en) 2008-02-21
RU2009107894A (ru) 2010-09-20
EP2059528A2 (en) 2009-05-20
WO2008020968A2 (en) 2008-02-21
CN101506232A (zh) 2009-08-12
WO2008020968A8 (en) 2009-08-06
US20090311216A1 (en) 2009-12-17
KR20090047452A (ko) 2009-05-12
MX2009001348A (es) 2009-05-11

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Legal Events

Date Code Title Description
B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 5A, 6A E 7A ANUIDADES.

B08I Publication cancelled [chapter 8.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.