BRPI0716802A2 - Expressão de tgf-beta em plastídeos - Google Patents

Expressão de tgf-beta em plastídeos

Info

Publication number: BRPI0716802A2
Authority: BR; Brazil
Prior art keywords: plastids; tgf; beta expression; beta; expression
Prior art date: 2006-09-11

Application number

BRPI0716802-0A2A

Other languages

English (en)

Inventor

Mark William James Ferguson

Hugh Gerard Laverty

Nicholas Occleston

Sharon O'kane

Martin Gisby

Anil Day

Phil Mellors

Original Assignee

Renovo Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-11

Filing date

2007-09-11

Publication date

2013-10-22

2007-09-11 Application filed by Renovo Ltd filed Critical Renovo Ltd

2013-10-22 Publication of BRPI0716802A2 publication Critical patent/BRPI0716802A2/pt

Links

210000002706 plastid Anatomy 0.000 title 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8214—Plastid transformation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Physical Education & Sports Medicine (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Rheumatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Gastroenterology & Hepatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Toxicology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)

BRPI0716802-0A2A 2006-09-11 2007-09-11 Expressão de tgf-beta em plastídeos BRPI0716802A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0617816.4A GB0617816D0 (en)	2006-09-11	2006-09-11	Nucleic acids and methods of protein expression
PCT/GB2007/003416 WO2008032035A1 (en)	2006-09-11	2007-09-11	Expression of tgf-beta in plastids

Publications (1)

Publication Number	Publication Date
BRPI0716802A2 true BRPI0716802A2 (pt)	2013-10-22

Family

ID=37232698

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0716802-0A2A BRPI0716802A2 (pt)	2006-09-11	2007-09-11	Expressão de tgf-beta em plastídeos

Country Status (12)

Country	Link
US (1)	US20090328250A1 (pt)
EP (1)	EP2074217A1 (pt)
JP (1)	JP2010502237A (pt)
CN (1)	CN101535484A (pt)
AR (1)	AR062749A1 (pt)
AU (1)	AU2007295983A1 (pt)
BR (1)	BRPI0716802A2 (pt)
CA (1)	CA2663146A1 (pt)
CL (1)	CL2007002745A1 (pt)
GB (1)	GB0617816D0 (pt)
TW (1)	TW200829697A (pt)
WO (1)	WO2008032035A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0604938D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Proteins, nucleic acids and medicaments
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
JP7667540B2 (ja) *	2019-07-21	2025-04-23	国立大学法人大阪大学	植物を用いた塩基性線維芽細胞増殖因子の製造方法
CN117280038A (zh) *	2021-01-04	2023-12-22	迪亚马特科学公司	基于植物的合成产物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4051848A (en) *	1976-03-01	1977-10-04	Levine Norman S	Synthetic skin wound dressing
US6559123B1 (en) *	1985-04-19	2003-05-06	Osi Pharmaceuticals, Inc.	Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof
US5135915A (en) *	1988-10-14	1992-08-04	Genentech, Inc.	Method for the treatment of grafts prior to transplantation using TGF-.beta.
GB8927546D0 (en) *	1989-12-06	1990-02-07	Ciba Geigy	Process for the production of biologically active tgf-beta
US6054122A (en) *	1990-11-27	2000-04-25	The American National Red Cross	Supplemented and unsupplemented tissue sealants, methods of their production and use
GB9206861D0 (en) *	1992-03-28	1992-05-13	Univ Manchester	Wound healing and treatment of fibrotic disorders
WO1993019783A1 (en) *	1992-04-01	1993-10-14	The Whittier Institute For Diabetes And Endocrinology	Methods of inhibiting or enhancing scar formation in the cns
US5411940A (en) *	1993-09-29	1995-05-02	Alcon Laboratories, Inc.	Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma
TW440566B (en) *	1994-07-25	2001-06-16	Novartis Ag	Novel process for the production of biologically active dimeric protein
AU725654B2 (en) *	1996-05-03	2000-10-19	Innogenetics N.V.	New medicaments containing gelatin cross-linked with oxidized polysaccharides
EP1074620A1 (en) *	1999-08-06	2001-02-07	HyGene AG	Monomeric protein of the TGF-beta family
TR200101032T2 (tr) *	1998-10-07	2001-10-22	Syngenta Participations Ag	Bitkilerdeki sağaltıcı yönden aktif proteinler.
EP1272649A2 (en) *	2000-04-03	2003-01-08	Monsanto Technology LLC	Method for producing authentic cytokines in plants
WO2001081371A1 (en) *	2000-04-25	2001-11-01	Otsuka Pharmaceutical Co., Ltd.	Gd3-mimetic peptides
US20040078851A1 (en) *	2000-05-02	2004-04-22	Ning Huang	Production of human growth factors in monocot seeds
JP2005525081A (ja) *	2001-06-05	2005-08-25	カレンケイ．オオイシ	植物からの生物活性ミュラー管抑制物質を含むＴＧＦ−βタンパク質の遺伝子発現および産生法
JP2006500037A (ja) *	2002-09-27	2006-01-05	セントロデインジエニエリアジエネテイカイバイオテクノロジア	被子植物遺伝子導入植物を作製するためのベクター
WO2006118617A2 (en) *	2004-12-23	2006-11-09	Chlorogen, Inc.	EXPRESSING TGF-β PROTEINS IN PLANT PLASTIDS
BRPI0613731A2 (pt) *	2005-07-12	2011-02-01	Renovo Ltd	composição farmacêutica, recipiente enchido previamente, bem como uso de um açúcar para aprimorar a recuperação e/ou aumentar a atividade biológica de um membro da superfamìlia tgf-beta

2006
- 2006-09-11 GB GBGB0617816.4A patent/GB0617816D0/en not_active Ceased
2007
- 2007-09-11 CN CNA2007800345861A patent/CN101535484A/zh active Pending
- 2007-09-11 AR ARP070104019A patent/AR062749A1/es not_active Application Discontinuation
- 2007-09-11 CA CA002663146A patent/CA2663146A1/en not_active Abandoned
- 2007-09-11 EP EP07804214A patent/EP2074217A1/en not_active Withdrawn
- 2007-09-11 TW TW096133966A patent/TW200829697A/zh unknown
- 2007-09-11 JP JP2009527880A patent/JP2010502237A/ja not_active Withdrawn
- 2007-09-11 BR BRPI0716802-0A2A patent/BRPI0716802A2/pt not_active IP Right Cessation
- 2007-09-11 AU AU2007295983A patent/AU2007295983A1/en not_active Abandoned
- 2007-09-11 US US12/440,688 patent/US20090328250A1/en not_active Abandoned
- 2007-09-11 WO PCT/GB2007/003416 patent/WO2008032035A1/en not_active Ceased
- 2007-09-24 CL CL200702745A patent/CL2007002745A1/es unknown

Also Published As

Publication number	Publication date
GB0617816D0 (en)	2006-10-18
CL2007002745A1 (es)	2008-10-03
AU2007295983A1 (en)	2008-03-20
TW200829697A (en)	2008-07-16
AR062749A1 (es)	2008-12-03
JP2010502237A (ja)	2010-01-28
US20090328250A1 (en)	2009-12-31
CN101535484A (zh)	2009-09-16
EP2074217A1 (en)	2009-07-01
WO2008032035A1 (en)	2008-03-20
CA2663146A1 (en)	2008-03-20

Legal Events

Date	Code	Title	Description
2014-06-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2014-08-26	B08L	Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]	Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 5A, 6A E 7A ANUIDADES.
2020-11-10	B08I	Publication cancelled [chapter 8.9 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.
2020-11-17	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES.
2021-03-09	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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