BRPI0717880A2 - Método para inibir a atividade de uma enzima e uso de um material compósito - Google Patents
Método para inibir a atividade de uma enzima e uso de um material compósitoInfo
- Publication number
- BRPI0717880A2 BRPI0717880A2 BRPI0717880-8A BRPI0717880A BRPI0717880A2 BR PI0717880 A2 BRPI0717880 A2 BR PI0717880A2 BR PI0717880 A BRPI0717880 A BR PI0717880A BR PI0717880 A2 BRPI0717880 A2 BR PI0717880A2
- Authority
- BR
- Brazil
- Prior art keywords
- composite material
- enzyme activity
- inhibiting enzyme
- nanoparticle
- metal
- Prior art date
Links
- 239000002131 composite material Substances 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002105 nanoparticle Substances 0.000 abstract 2
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 230000018791 negative regulation of catalytic activity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Optics & Photonics (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/554,214 US20080103459A1 (en) | 2006-10-30 | 2006-10-30 | Enzyme inhibition using nanoparticles |
| PCT/US2007/082603 WO2008055049A2 (en) | 2006-10-30 | 2007-10-26 | Enzyme inhibition using nanoparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0717880A2 true BRPI0717880A2 (pt) | 2015-06-16 |
Family
ID=39331215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0717880-8A BRPI0717880A2 (pt) | 2006-10-30 | 2007-10-26 | Método para inibir a atividade de uma enzima e uso de um material compósito |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080103459A1 (pt) |
| EP (1) | EP2083796B1 (pt) |
| JP (1) | JP2010508356A (pt) |
| CN (1) | CN101557800B (pt) |
| AT (1) | ATE501759T1 (pt) |
| AU (1) | AU2007313799A1 (pt) |
| BR (1) | BRPI0717880A2 (pt) |
| CA (1) | CA2667953A1 (pt) |
| CO (1) | CO6210804A2 (pt) |
| DE (1) | DE602007013266D1 (pt) |
| ES (1) | ES2360638T3 (pt) |
| MX (1) | MX2009004787A (pt) |
| RU (1) | RU2009120470A (pt) |
| WO (1) | WO2008055049A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060134052A1 (en) * | 2004-12-17 | 2006-06-22 | Cossa Anthony J | Compositions comprising polymeric emulsifiers and methods of using same |
| RU2460532C1 (ru) * | 2011-04-28 | 2012-09-10 | Учреждение Российской академии наук Институт энергетических проблем химической физики РАН | Препарат, ускоряющий ранозаживление |
| US20140154468A1 (en) * | 2012-12-05 | 2014-06-05 | National Taiwan University | Composite of size-controllable metal nanoparticales and the method of making the same |
| CN105025976B (zh) * | 2013-01-21 | 2019-01-08 | 白雁美学公司 | 微型针、微型针的制造模具和制造方法 |
| JP2014234334A (ja) * | 2013-06-04 | 2014-12-15 | Dic株式会社 | 金属ナノ粒子/層状鉱物複合体及びその製造方法 |
| US20180243336A1 (en) * | 2015-08-28 | 2018-08-30 | The Regents Of The University Of Michigan | Antimicrobial and enzyme inhibitory zinc oxide nanoparticles |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556560A (en) * | 1983-01-24 | 1985-12-03 | The Procter & Gamble Company | Methods for the treatment and prophylaxis of diaper rash and diaper dermatitis |
| FR2651125B1 (fr) * | 1989-08-23 | 1992-10-02 | Roussel Uclaf | Compositions pharmaceutiques de type "pates a l'eau". |
| US6492453B1 (en) | 1999-09-24 | 2002-12-10 | Alphagary Corporation | Low smoke emission, low corrosivity, low toxicity, low heat release, flame retardant, zero halogen polymeric compositions |
| US6464994B1 (en) * | 2000-01-19 | 2002-10-15 | Mentis Technologies, L.C. | Diaper dermatitis preventative medication and a method for making and using same |
| US20030185901A1 (en) * | 2000-07-27 | 2003-10-02 | Burrell Robert E. | Methods of treating conditions with a metal-containing material |
| US6518324B1 (en) | 2000-11-28 | 2003-02-11 | Atofina Chemicals, Inc. | Polymer foam containing nanoclay |
| AU2002253882A1 (en) | 2001-01-30 | 2002-08-28 | The Procter And Gamble Company | Coating compositions for modifying surfaces |
| CA2445734A1 (en) * | 2001-04-23 | 2002-10-31 | Nucryst Pharmaceuticals Corp. | Medicament containing a metal such as silver, gold, platinum or palladium as an antimicrobial agent and their use to induce apoptosis in cancerous tissue |
| KR100467205B1 (ko) * | 2001-07-12 | 2005-01-24 | 주식회사 엘지생활건강 | 항균제를 함유하는 일회용 흡수제품 |
| US20030104019A1 (en) * | 2001-11-01 | 2003-06-05 | Mcculloch Laura | Composition for reducing enzymatic irritation to skin |
| US6743463B2 (en) | 2002-03-28 | 2004-06-01 | Scimed Life Systems, Inc. | Method for spray-coating a medical device having a tubular wall such as a stent |
| BRPI0416114A (pt) * | 2003-10-30 | 2007-01-02 | Mcneil Ppc Inc | materiais compósitos compreendendo nanopartìculas carregadas com metal |
| JP2005287985A (ja) * | 2004-04-05 | 2005-10-20 | Gha:Kk | 炎症/臭い抑制部材及びその製造方法並びにこれを用いた義体及びギブス |
| EP1880213A4 (en) * | 2005-01-05 | 2010-06-23 | Robert Holladay | SILVER / WATER, SILVER GEL AND SILVER BASE COMPOSITIONS AND METHOD FOR THE PRODUCTION AND USE THEREOF |
-
2006
- 2006-10-30 US US11/554,214 patent/US20080103459A1/en not_active Abandoned
-
2007
- 2007-10-26 DE DE602007013266T patent/DE602007013266D1/de active Active
- 2007-10-26 JP JP2009535403A patent/JP2010508356A/ja active Pending
- 2007-10-26 CA CA002667953A patent/CA2667953A1/en not_active Abandoned
- 2007-10-26 RU RU2009120470/15A patent/RU2009120470A/ru not_active Application Discontinuation
- 2007-10-26 WO PCT/US2007/082603 patent/WO2008055049A2/en not_active Ceased
- 2007-10-26 AT AT07868587T patent/ATE501759T1/de not_active IP Right Cessation
- 2007-10-26 MX MX2009004787A patent/MX2009004787A/es active IP Right Grant
- 2007-10-26 ES ES07868587T patent/ES2360638T3/es active Active
- 2007-10-26 EP EP07868587A patent/EP2083796B1/en not_active Not-in-force
- 2007-10-26 BR BRPI0717880-8A patent/BRPI0717880A2/pt not_active IP Right Cessation
- 2007-10-26 AU AU2007313799A patent/AU2007313799A1/en not_active Abandoned
- 2007-10-26 CN CN2007800465613A patent/CN101557800B/zh not_active Expired - Fee Related
-
2009
- 2009-05-11 CO CO09047337A patent/CO6210804A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008055049A3 (en) | 2008-10-02 |
| CO6210804A2 (es) | 2010-10-20 |
| CA2667953A1 (en) | 2008-05-08 |
| DE602007013266D1 (de) | 2011-04-28 |
| EP2083796B1 (en) | 2011-03-16 |
| MX2009004787A (es) | 2009-08-12 |
| WO2008055049A2 (en) | 2008-05-08 |
| CN101557800B (zh) | 2013-04-24 |
| US20080103459A1 (en) | 2008-05-01 |
| EP2083796A2 (en) | 2009-08-05 |
| CN101557800A (zh) | 2009-10-14 |
| RU2009120470A (ru) | 2010-12-10 |
| JP2010508356A (ja) | 2010-03-18 |
| ES2360638T3 (es) | 2011-06-07 |
| AU2007313799A1 (en) | 2008-05-08 |
| ATE501759T1 (de) | 2011-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |