BRPI0718444A2 - Inibidores de receptor de adp de plaqueta - Google Patents
Inibidores de receptor de adp de plaquetaInfo
- Publication number
- BRPI0718444A2 BRPI0718444A2 BRPI0718444-1A2A BRPI0718444A BRPI0718444A2 BR PI0718444 A2 BRPI0718444 A2 BR PI0718444A2 BR PI0718444 A BRPI0718444 A BR PI0718444A BR PI0718444 A2 BRPI0718444 A2 BR PI0718444A2
- Authority
- BR
- Brazil
- Prior art keywords
- inhibitors
- receiver
- platelet adp
- adp
- platelet
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84632806P | 2006-09-20 | 2006-09-20 | |
| US11/856,616 US7834023B2 (en) | 2006-09-20 | 2007-09-17 | Substituted dihydroquinazolines as platelet ADP receptor inhibitors |
| PCT/US2007/079076 WO2008036843A2 (en) | 2006-09-20 | 2007-09-20 | Nitrogen containing substituted heterocycles as platelet adp receptor inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0718444A2 true BRPI0718444A2 (pt) | 2013-11-19 |
Family
ID=39048759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0718444-1A2A BRPI0718444A2 (pt) | 2006-09-20 | 2007-09-20 | Inibidores de receptor de adp de plaqueta |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7834023B2 (pt) |
| EP (1) | EP2094272B1 (pt) |
| JP (1) | JP5266232B2 (pt) |
| KR (1) | KR20090057314A (pt) |
| AU (1) | AU2007299723A1 (pt) |
| BR (1) | BRPI0718444A2 (pt) |
| CA (1) | CA2664411A1 (pt) |
| CO (1) | CO6160324A2 (pt) |
| IL (1) | IL197726A0 (pt) |
| MA (1) | MA30775B1 (pt) |
| MX (1) | MX2009003017A (pt) |
| NO (1) | NO20091331L (pt) |
| NZ (1) | NZ576162A (pt) |
| RU (1) | RU2009114827A (pt) |
| TN (1) | TN2009000091A1 (pt) |
| WO (1) | WO2008036843A2 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100260825A1 (en) * | 2009-04-13 | 2010-10-14 | Nair Madhavan G | Antifolates for the treatment of cardiovascular, inflammatory, neoplastic, autoimmune and related diseases in sublingual dosage units, film strips, or skin patches |
| EP2723718A1 (en) | 2011-06-24 | 2014-04-30 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
| US8710043B2 (en) | 2011-06-24 | 2014-04-29 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| AU2013305759C1 (en) | 2012-08-23 | 2018-01-18 | Janssen Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| TN2017000508A1 (en) | 2015-06-26 | 2019-04-12 | Takeda Pharmaceuticals Co | 2,3-dihydro-4h-1,3-benzoxazin-4-one derivatives as modulators of cholinergic muscarinic m1 receptor |
| EP3366679B1 (en) | 2015-10-20 | 2021-03-24 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| JP7080346B2 (ja) * | 2018-04-30 | 2022-06-03 | ユニティ バイオテクノロジー インコーポレイテッド | 老化細胞によって引き起こされるかまたは媒介される状態の臨床管理における使用のためおよびがんを治療するための、Ｂｃｌファミリーアンタゴニストであるホスホノアミダート |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL135175B2 (en) * | 1983-12-22 | 1985-10-31 | Method of printing of articles made of polyamide fibres | |
| DE19650975A1 (de) * | 1996-12-09 | 1998-06-10 | Basf Ag | Neue heterocyclisch substituierte Benzamide und deren Anwendung |
| RU2260007C2 (ru) | 1999-03-17 | 2005-09-10 | Астразенека Аб | Производные амида, способ их получения (варианты), фармацевтическая композиция, способ ингибирования |
| US6906063B2 (en) * | 2000-02-04 | 2005-06-14 | Portola Pharmaceuticals, Inc. | Platelet ADP receptor inhibitors |
| FR2837201A1 (fr) * | 2002-03-18 | 2003-09-19 | Servier Lab | Nouveaux composes derives de la quinazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP2005097276A (ja) * | 2003-08-22 | 2005-04-14 | Takeda Chem Ind Ltd | 縮合ピリミジン誘導体およびその用途 |
| AU2004278030C1 (en) | 2003-10-03 | 2010-12-02 | Portola Pharmaceuticals, Inc. | 2,4-Dioxo-3-quinazolinylaryl sulfonylureas |
| JP4879745B2 (ja) * | 2003-10-03 | 2012-02-22 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 置換イソキノリノン |
| CA2568756A1 (en) | 2004-06-15 | 2005-12-29 | Astrazeneca Ab | Substituted quinazolones as anti-cancer agents |
| US20070010537A1 (en) * | 2004-08-20 | 2007-01-11 | Kazumasa Hamamura | Fused pyramidine derivative and use thereof |
| CN101031565B (zh) | 2004-09-29 | 2010-09-29 | 博尔托拉制药公司 | 取代的2h-1,3-苯并噁嗪-4(3h)-酮 |
| JP2009541310A (ja) | 2006-06-19 | 2009-11-26 | アストラゼネカ・アクチエボラーグ | イソキノリン誘導体およびサイトカイン仲介疾患の阻害剤としてのそれらの使用 |
-
2007
- 2007-09-17 US US11/856,616 patent/US7834023B2/en not_active Expired - Fee Related
- 2007-09-20 RU RU2009114827/15A patent/RU2009114827A/ru not_active Application Discontinuation
- 2007-09-20 MX MX2009003017A patent/MX2009003017A/es active IP Right Grant
- 2007-09-20 AU AU2007299723A patent/AU2007299723A1/en not_active Abandoned
- 2007-09-20 EP EP07842909.9A patent/EP2094272B1/en active Active
- 2007-09-20 CA CA002664411A patent/CA2664411A1/en not_active Abandoned
- 2007-09-20 WO PCT/US2007/079076 patent/WO2008036843A2/en not_active Ceased
- 2007-09-20 BR BRPI0718444-1A2A patent/BRPI0718444A2/pt not_active IP Right Cessation
- 2007-09-20 KR KR1020097007782A patent/KR20090057314A/ko not_active Withdrawn
- 2007-09-20 NZ NZ576162A patent/NZ576162A/en not_active IP Right Cessation
- 2007-09-20 JP JP2009529403A patent/JP5266232B2/ja not_active Expired - Fee Related
-
2009
- 2009-03-19 TN TN2009000091A patent/TN2009000091A1/fr unknown
- 2009-03-19 IL IL197726A patent/IL197726A0/en unknown
- 2009-03-20 CO CO09029291A patent/CO6160324A2/es unknown
- 2009-03-31 NO NO20091331A patent/NO20091331L/no not_active Application Discontinuation
- 2009-04-02 MA MA31756A patent/MA30775B1/fr unknown
-
2010
- 2010-10-26 US US12/912,367 patent/US20110098247A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO6160324A2 (es) | 2010-05-20 |
| JP5266232B2 (ja) | 2013-08-21 |
| JP2010504357A (ja) | 2010-02-12 |
| US7834023B2 (en) | 2010-11-16 |
| NO20091331L (no) | 2009-05-20 |
| MA30775B1 (fr) | 2009-10-01 |
| WO2008036843A3 (en) | 2008-05-15 |
| KR20090057314A (ko) | 2009-06-04 |
| US20080132499A1 (en) | 2008-06-05 |
| HK1131058A1 (en) | 2010-01-15 |
| US20110098247A1 (en) | 2011-04-28 |
| NZ576162A (en) | 2012-03-30 |
| CA2664411A1 (en) | 2008-03-27 |
| AU2007299723A1 (en) | 2008-03-27 |
| TN2009000091A1 (en) | 2010-08-19 |
| MX2009003017A (es) | 2009-06-08 |
| WO2008036843A2 (en) | 2008-03-27 |
| IL197726A0 (en) | 2009-12-24 |
| EP2094272B1 (en) | 2014-03-26 |
| EP2094272A2 (en) | 2009-09-02 |
| RU2009114827A (ru) | 2010-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08L | Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette] |
Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 6A E 7A ANUIDADES. |
|
| B08I | Publication cancelled [chapter 8.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |