BRPI0719430B8 - molécula de anticorpo isolada, composição, uso de uma molécula de anticorpo ou de uma composição, e, molécula de ácido nucleico isolado - Google Patents

molécula de anticorpo isolada, composição, uso de uma molécula de anticorpo ou de uma composição, e, molécula de ácido nucleico isolado

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Publication number
BRPI0719430B8
BRPI0719430B8 BRPI0719430A BRPI0719430A BRPI0719430B8 BR PI0719430 B8 BRPI0719430 B8 BR PI0719430B8 BR PI0719430 A BRPI0719430 A BR PI0719430A BR PI0719430 A BRPI0719430 A BR PI0719430A BR PI0719430 B8 BRPI0719430 B8 BR PI0719430B8
Authority
BR
Brazil
Prior art keywords
isolated
composition
antibody molecule
molecule
antibody
Prior art date
Application number
BRPI0719430A
Other languages
English (en)
Inventor
Mallinder Philip
Charles Cruwys Simon
Godfrey Lane Steven
Original Assignee
Astrazeneca Ab
Medimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Medimmune Ltd filed Critical Astrazeneca Ab
Publication of BRPI0719430A2 publication Critical patent/BRPI0719430A2/pt
Publication of BRPI0719430B1 publication Critical patent/BRPI0719430B1/pt
Publication of BRPI0719430B8 publication Critical patent/BRPI0719430B8/pt

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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
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Abstract

membro de ligação isolado para il-6 humana, molécula de anticorpo isolada, domínios vh e vl isolados, composição, uso de um membro de ligação isolado, ou molécula de anticorpo, molécula de ácido nucleico isolado, célula hospedeira, e, métodos para produzir um membro de ligação, uma molécula de anticorpo ou um domínio vh ou vl de anticorpo, para produzir um domínio de ligação a antígeno de anticorpo para il-6 e para produzir uma composição de molécula de anticorpo. membro de ligação, p. ex., moléculas de anticorpo humano, que se ligam a interleucina-6 (il-6) e neutralizam seus efeitos biológicos. uso de membros de ligação para il-6 em tratamento médico, p. ex., para tratar tumores e doenças inflamatórias associadas a il-6.
BRPI0719430A 2006-11-30 2007-11-28 molécula de anticorpo isolada, composição, uso de uma molécula de anticorpo ou de uma composição, e, molécula de ácido nucleico isolado BRPI0719430B8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US86170406P 2006-11-30 2006-11-30
US60/861,704 2006-11-30
US60/861704 2006-11-30
PCT/GB2007/004527 WO2008065378A2 (en) 2006-11-30 2007-11-28 Binding members for interleukin-6

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