BRPI0800085A2 - composição farmacêutica e curativo para tratamento de lesões de pele, bem como uso de sal de cério associado a uma matriz de colágeno - Google Patents

composição farmacêutica e curativo para tratamento de lesões de pele, bem como uso de sal de cério associado a uma matriz de colágeno

Info

Publication number
BRPI0800085A2
BRPI0800085A2 BRPI0800085-9A BRPI0800085A BRPI0800085A2 BR PI0800085 A2 BRPI0800085 A2 BR PI0800085A2 BR PI0800085 A BRPI0800085 A BR PI0800085A BR PI0800085 A2 BRPI0800085 A2 BR PI0800085A2
Authority
BR
Brazil
Prior art keywords
present
skin
skin lesions
lesions
pharmaceutical composition
Prior art date
Application number
BRPI0800085-9A
Other languages
English (en)
Inventor
Cruz Luis Eduardo Da
Original Assignee
Cruz Luis Eduardo Da
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cruz Luis Eduardo Da filed Critical Cruz Luis Eduardo Da
Priority to BRPI0800085-9A priority Critical patent/BRPI0800085A2/pt
Priority to US12/202,599 priority patent/US20090202434A1/en
Priority to PT97078257T priority patent/PT2249879E/pt
Priority to HK11104791.0A priority patent/HK1150785B/en
Priority to EP09707825.7A priority patent/EP2249879B1/en
Priority to CN200980112850.8A priority patent/CN102105177B/zh
Priority to JP2010545335A priority patent/JP5596561B2/ja
Priority to US12/866,726 priority patent/US8507652B2/en
Priority to ES09707825.7T priority patent/ES2467668T3/es
Priority to BRPI0908149-6A priority patent/BRPI0908149B1/pt
Priority to PCT/BR2009/000031 priority patent/WO2009097672A2/en
Publication of BRPI0800085A2 publication Critical patent/BRPI0800085A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1213—Semi-solid forms, gels, hydrogels, ointments, fats and waxes that are solid at room temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPOSIçãO FARMACêUTICA E CURATIVO PARA TRATAMENTO DE LESõES DE PELE, BEM COMO USO DE SAL DE CéRIO ASSOCIADO A UMA MATRIZ DE COLáGENO. A presente invenção refere-se a uma composição farmacêutica para tratamento de lesões de pele compreendendo um sal de cério sobre uma matriz de colágeno e um veículo dermatologicamente aceitável. A presente invenção também se refere a um curativo para tratamento de lesões de pele compreendendo a composição farmacêutica da presente invenção. A presente invenção refere-se ainda ao uso de um sal de cério associado a colágeno na preparação da composição farmacêutica ou curativo de acordo com a presente invenção. A composição da presente invenção pode ser utilizada para aplicação tópica em diversos tipos de lesões, tais como, lesões de pele que envolva a liberação no organismo humano ou animal de toxinas relacionadas a proteínas microbianas ou aquelas denominadas HSP; queimaduras que envolvem a formação da toxina da pele queimada ou LPC; lesões cutâneas ulceradas crónicas nas quais haja produção excessiva de proteinases; lesões de pele de difícil resolução nas quais seja necessário controle da produção excessiva de exsudato; e lesões de pele infectadas ou colonizadas de maneira crítica.
BRPI0800085-9A 2008-02-08 2008-02-08 composição farmacêutica e curativo para tratamento de lesões de pele, bem como uso de sal de cério associado a uma matriz de colágeno BRPI0800085A2 (pt)

Priority Applications (11)

Application Number Priority Date Filing Date Title
BRPI0800085-9A BRPI0800085A2 (pt) 2008-02-08 2008-02-08 composição farmacêutica e curativo para tratamento de lesões de pele, bem como uso de sal de cério associado a uma matriz de colágeno
US12/202,599 US20090202434A1 (en) 2008-02-08 2008-09-02 Pharmaceutical Composition and Dressing for Treating Skin Lesion, as Well as the Use of Cerium Salt Associated With a Collagen Matrix
PT97078257T PT2249879E (pt) 2008-02-08 2009-02-09 Composição farmacêutica, curativo e método para tratar uma lesão da pele, composição intermediária e processo para preparar o dito curativo, e uso de sal de cério associado com uma matriz de colagénio
HK11104791.0A HK1150785B (en) 2008-02-08 2009-02-09 Pharmaceutical composition, dressing and method for treating skin lesion, intermediate composition and process for preparing said dressing, and use of cerium salt associated with a collagen matrix
EP09707825.7A EP2249879B1 (en) 2008-02-08 2009-02-09 Pharmaceutical composition, dressing and method for treating skin lesion, intermediate composition and process for preparing said dressing, and use of cerium salt associated with a collagen matrix
CN200980112850.8A CN102105177B (zh) 2008-02-08 2009-02-09 治疗皮肤损伤的药物组合物、敷料和方法,用于制备所述敷料的中间组合物和方法,以及与胶原基质缔合的铈盐的用途
JP2010545335A JP5596561B2 (ja) 2008-02-08 2009-02-09 皮膚の病変を処置するための医薬組成物、ドレッシング材及び方法、該ドレッシング材を調製するための中間組成物及びプロセス、並びにコラーゲンマトリックスと併せたセリウム塩の使用
US12/866,726 US8507652B2 (en) 2008-02-08 2009-02-09 Pharmaceutical composition, dressing and method for treating skin lesion, intermediate composition and process for preparing said dressing, and use of cerium salt associated with a collagen matrix
ES09707825.7T ES2467668T3 (es) 2008-02-08 2009-02-09 Composicón farmaceutica, vendaje y método para tratar lesión cutánea, composición intermedia y proceso para preparar dicho vendaje y uso de sal de cerio asociada con una matriz de colágeno
BRPI0908149-6A BRPI0908149B1 (pt) 2008-02-08 2009-02-09 Composição farmacêutica e curativo para o tratamento de lesões de pele, processo para a preparação do dito curativo, e uso de sal de cério associado a uma matriz de colágeno
PCT/BR2009/000031 WO2009097672A2 (en) 2008-02-08 2009-02-09 Pharmaceutical composition, dressing and method for treating skin lesion, intermediate composition and process for preparing said dressing, and use of cerium salt associated with a collagen matrix

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0800085-9A BRPI0800085A2 (pt) 2008-02-08 2008-02-08 composição farmacêutica e curativo para tratamento de lesões de pele, bem como uso de sal de cério associado a uma matriz de colágeno

Publications (1)

Publication Number Publication Date
BRPI0800085A2 true BRPI0800085A2 (pt) 2009-09-29

Family

ID=40939036

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0800085-9A BRPI0800085A2 (pt) 2008-02-08 2008-02-08 composição farmacêutica e curativo para tratamento de lesões de pele, bem como uso de sal de cério associado a uma matriz de colágeno
BRPI0908149-6A BRPI0908149B1 (pt) 2008-02-08 2009-02-09 Composição farmacêutica e curativo para o tratamento de lesões de pele, processo para a preparação do dito curativo, e uso de sal de cério associado a uma matriz de colágeno

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0908149-6A BRPI0908149B1 (pt) 2008-02-08 2009-02-09 Composição farmacêutica e curativo para o tratamento de lesões de pele, processo para a preparação do dito curativo, e uso de sal de cério associado a uma matriz de colágeno

Country Status (8)

Country Link
US (1) US20090202434A1 (pt)
EP (1) EP2249879B1 (pt)
JP (1) JP5596561B2 (pt)
CN (1) CN102105177B (pt)
BR (2) BRPI0800085A2 (pt)
ES (1) ES2467668T3 (pt)
PT (1) PT2249879E (pt)
WO (1) WO2009097672A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2767400A1 (en) * 2009-07-06 2011-01-13 Molycorp Minerals Llc Ceria for use as an antimicrobial barrier and disinfectant in a wound dressing
US9233863B2 (en) 2011-04-13 2016-01-12 Molycorp Minerals, Llc Rare earth removal of hydrated and hydroxyl species
MX370462B (es) 2014-03-07 2019-12-13 Secure Natural Resources Llc Oxido de cerio (iv) con propiedades de remocion de arsenico excepcionales.
CN104474535A (zh) * 2014-12-10 2015-04-01 成都新际生物活性胶原开发有限公司 一种治疗糖尿病足的水溶性凝胶
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
EP3283098A1 (en) * 2015-04-15 2018-02-21 Welland Medical Limited Composition comprising collagen and honey
CN115463242B (zh) * 2022-09-27 2023-09-08 中国地质大学（武汉） 一种高岭土止血纱布及其制备方法
CN119015480A (zh) * 2024-08-20 2024-11-26 上海市浦东新区人民医院 一种用于外伤性出血快速止血的止血粉、其制备方法及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4746504A (en) * 1986-03-14 1988-05-24 Bio-Technology General Corp. Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
JP2719671B2 (ja) * 1989-07-11 1998-02-25 日本ゼオン株式会社 創傷被覆材
GB9001878D0 (en) * 1990-01-26 1990-03-28 Beam Tech Ltd Alginate materials
EG20380A (en) * 1991-10-16 1999-02-28 Richardson Vicks Inc Enhanced skin penetration system for improved topical delivery of drugs
JP3357094B2 (ja) * 1991-10-18 2002-12-16 株式会社クラレ 抗菌性重合性組成物、それより得られるポリマーおよび用品
GB9209327D0 (en) * 1992-04-30 1992-06-17 Johnson & Johnson Medical Freeze-dried pad
FR2759692B1 (fr) * 1997-02-18 1999-04-30 Sod Conseils Rech Applic Argiles associees a des ions de cerium (iii), medicaments a base d'argile et d'ions cerium (iii), compositions pharmaceutiques les contenant et leur utilisation pour traiter des infections
GB2382775B (en) * 2001-12-06 2005-05-25 Johnson & Johnson Medical Ltd Controlled release therapeutic wound dressings

Also Published As

Publication number Publication date
PT2249879E (pt) 2014-06-05
WO2009097672A3 (en) 2010-05-20
ES2467668T3 (es) 2014-06-12
CN102105177B (zh) 2014-11-05
JP5596561B2 (ja) 2014-09-24
WO2009097672A2 (en) 2009-08-13
HK1150785A1 (en) 2012-01-13
JP2011511013A (ja) 2011-04-07
US20090202434A1 (en) 2009-08-13
EP2249879B1 (en) 2014-03-26
EP2249879A2 (en) 2010-11-17
CN102105177A (zh) 2011-06-22
BRPI0908149A2 (pt) 2015-08-11
BRPI0908149B1 (pt) 2018-05-02

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]