BRPI0800357A2 - method for producing a stabilized vaccine - Google Patents

method for producing a stabilized vaccine

Info

Publication number
BRPI0800357A2
BRPI0800357A2 BRPI0800357-2A BRPI0800357A BRPI0800357A2 BR PI0800357 A2 BRPI0800357 A2 BR PI0800357A2 BR PI0800357 A BRPI0800357 A BR PI0800357A BR PI0800357 A2 BRPI0800357 A2 BR PI0800357A2
Authority
BR
Brazil
Prior art keywords
vaccine
stabilized
producing
hydrostatic pressure
high hydrostatic
Prior art date
Application number
BRPI0800357-2A
Other languages
Portuguese (pt)
Inventor
Luciane Pinto Gaspar
Silva Freire Marcos Da
De Oliveira Andrea Cheble
Da Silva Jerson Lima
Original Assignee
Fundacao Oswaldo Cruz
Univ Fed Do Rio De Janeiro Ufrj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Oswaldo Cruz, Univ Fed Do Rio De Janeiro Ufrj filed Critical Fundacao Oswaldo Cruz
Priority to BRPI0800357-2A priority Critical patent/BRPI0800357A2/en
Priority to PCT/BR2009/000058 priority patent/WO2009111849A1/en
Publication of BRPI0800357A2 publication Critical patent/BRPI0800357A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32051—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32651—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

MéTODO PARA PRODUçãO DE UMA VACINA ESTABILIZADA A presente invenção se refere ao campo das vacinas, mais particularmente, à estabilização das três cepas vacinais da poliomielite, presentes na Vacina Oral contra a Poliomielite (VOP) . A alta pressão hidrostática é uma tecnologia que é extremamente segura, limpa e económica. Além disso, uma vacina comercial estabilizada pela ação da alta pressão hidrostática evita a necessidade de energia elétrica para armazenamento do material.METHOD FOR PRODUCTION OF A STABILIZED VACCINE The present invention relates to the field of vaccines, more particularly, to the stabilization of the three polio vaccine strains present in the Oral Polio Vaccine (VOP). High hydrostatic pressure is a technology that is extremely safe, clean and economical. In addition, a commercial vaccine stabilized by the action of high hydrostatic pressure avoids the need for electrical energy for material storage.

BRPI0800357-2A 2008-03-10 2008-03-10 method for producing a stabilized vaccine BRPI0800357A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0800357-2A BRPI0800357A2 (en) 2008-03-10 2008-03-10 method for producing a stabilized vaccine
PCT/BR2009/000058 WO2009111849A1 (en) 2008-03-10 2009-03-10 Method for stabilized vaccine production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0800357-2A BRPI0800357A2 (en) 2008-03-10 2008-03-10 method for producing a stabilized vaccine

Publications (1)

Publication Number Publication Date
BRPI0800357A2 true BRPI0800357A2 (en) 2009-10-27

Family

ID=41064685

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0800357-2A BRPI0800357A2 (en) 2008-03-10 2008-03-10 method for producing a stabilized vaccine

Country Status (2)

Country Link
BR (1) BRPI0800357A2 (en)
WO (1) WO2009111849A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2012MU00206A (en) 2012-01-20 2013-08-09
NZ706288A (en) 2012-08-30 2016-06-24 Merial Inc Expression of chimeric ksac protein and method of producing soluble proteins by high pressure
ZA201501696B (en) 2012-08-30 2016-01-27 Merial Ltd Hyperbaric device and methods for producing inactivated vaccines and for refolding/solubilizing recombinant proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2065023A1 (en) * 1989-08-15 1991-02-16 Brent Dorval Stabilized vaccine compositions
WO1997033612A1 (en) * 1996-03-15 1997-09-18 Immunotherapy, Inc. Dialdehydes as immunostimulatory adjuvants and cross-linkers for producing immunogenic preparations and generating pressure and cross-link treated cells for enhancing and augmenting the immune response against cancers, tumors and pathogenic diseases
US6270723B1 (en) * 1998-06-15 2001-08-07 Bbi Bioseq, Inc. Rapid cryobaric sterilization and vaccine preparation
CN1099295C (en) * 1998-09-04 2003-01-22 中国科学院上海生物化学研究所 Infectious cloacal bursa virus vaccine for chicken and its preparing process and application
WO2004042001A2 (en) * 2002-05-17 2004-05-21 Emory University Virus-like particles, methods of preparation, and immonogenic compositions

Also Published As

Publication number Publication date
WO2009111849A1 (en) 2009-09-17

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: FUNDACAO OSWALDO CRUZ - FIOCRUZ (BR/RJ) , UNIVERSI

Free format text: TRANSFERIDO PARTE DOS DIREITOS DE: FUNDACAO OSWALDO CRUZ - FIOCRUZ

B03A Publication of an application: publication of a patent application or of a certificate of addition of invention
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07D Technical examination (opinion) related to article 229 of industrial property law
B07E Notice of approval relating to section 229 industrial property law

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal