BRPI0801740A2 - agente de revestimento para stent de liberaÇço de fÁrmaco, mÉtodo para sua preparaÇço e stent de liberaÇço de fÁrmaco revestido com ele - Google Patents
agente de revestimento para stent de liberaÇço de fÁrmaco, mÉtodo para sua preparaÇço e stent de liberaÇço de fÁrmaco revestido com eleInfo
- Publication number
- BRPI0801740A2 BRPI0801740A2 BRPI0801740-9A BRPI0801740A BRPI0801740A2 BR PI0801740 A2 BRPI0801740 A2 BR PI0801740A2 BR PI0801740 A BRPI0801740 A BR PI0801740A BR PI0801740 A2 BRPI0801740 A2 BR PI0801740A2
- Authority
- BR
- Brazil
- Prior art keywords
- drug release
- release stent
- coating agent
- preparation
- coated therewith
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 6
- 229940079593 drug Drugs 0.000 title abstract 6
- 239000011248 coating agent Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- 239000000126 substance Substances 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 229920001218 Pullulan Polymers 0.000 abstract 1
- 239000004373 Pullulan Substances 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920002635 polyurethane Polymers 0.000 abstract 1
- 239000004814 polyurethane Substances 0.000 abstract 1
- 235000019423 pullulan Nutrition 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
AGENTE DE REVESTIMENTO PARA STENT DE LIBERAÇçO DE FÁRMACO, MÉTODO PARA SUA PREPARAÇçO E STENT DE LIBERAÇçO DE FÁRMACO REVESTIDO COM ELE. A presente invenção refere-se a um agente de revestimento para stents de liberação de fármaco, um método para sua preparação e um stent de liberação de fármaco revestido com ele. O agente de revestimento compreende um material biologicamente ativo e um material de revestimento selecionado dentre acetato de pululano, representado pela Fórmula Química 1 que segue, e uma mistura de tensoativo de poliuretano. [Fórmula Química 1]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020070053877A KR100888219B1 (ko) | 2007-06-01 | 2007-06-01 | 약물 방출 스텐트용 코팅제, 그의 제조방법 및 이 코팅제로코팅된 약물 방출 스텐트 |
| KR1020070103080A KR100916750B1 (ko) | 2007-10-12 | 2007-10-12 | 약물 방출 스텐트용 코팅제와 약물 방출 스텐트용 코팅제의제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0801740A2 true BRPI0801740A2 (pt) | 2009-02-10 |
Family
ID=39790909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0801740-9A BRPI0801740A2 (pt) | 2007-06-01 | 2008-06-02 | agente de revestimento para stent de liberaÇço de fÁrmaco, mÉtodo para sua preparaÇço e stent de liberaÇço de fÁrmaco revestido com ele |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8017143B2 (pt) |
| EP (2) | EP2238993A3 (pt) |
| JP (1) | JP5006261B2 (pt) |
| AU (1) | AU2008202283B2 (pt) |
| BR (1) | BRPI0801740A2 (pt) |
| CA (1) | CA2632891A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5860480B2 (ja) | 2011-01-11 | 2016-02-16 | キャプシュゲル・ベルジウム・エヌ・ヴィ | プルランを含む新しい硬カプセル |
| KR20120135689A (ko) * | 2011-06-07 | 2012-12-17 | (주) 태웅메디칼 | 약물 방출 스텐트 코팅제의 제조방법 및 이에 의해 제조된 약물 방출 스텐트 코팅제 |
| WO2014169137A1 (en) | 2013-04-10 | 2014-10-16 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
| US10241109B2 (en) | 2013-11-08 | 2019-03-26 | Mcmaster University | Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions |
| KR101765335B1 (ko) * | 2014-09-26 | 2017-08-22 | 서울대학교산학협력단 | 암 세포 조영용 mri 조영제 조성물 |
| CA3059529A1 (en) | 2017-04-14 | 2018-10-18 | Capsugel Belgium Nv | Process for making pullulan |
| CN110678170A (zh) | 2017-04-14 | 2020-01-10 | 比利时胶囊公司 | 普鲁兰多糖胶囊 |
| WO2023091976A1 (en) | 2021-11-17 | 2023-05-25 | PanTher Therapeutics, Inc. | Implantable and biodegradable drug delivery devices and methods of use thereof |
| JP2025538459A (ja) | 2022-11-17 | 2025-11-28 | パンサー セラピューティクス,インコーポレイティド | 膵臓がんを治療する方法 |
| CN119587763B (zh) * | 2024-12-16 | 2025-09-05 | 上海交通大学 | 一种用于周围神经缺损修复的具有两面神结构的氢气和镁离子泵导管及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63313722A (ja) * | 1987-06-15 | 1988-12-21 | Towa Yakuhin Kk | 経口用抗生物質の徐放化を目的としたプルランアセテ−トマイクロカプセル製剤の製造法 |
| US5092877A (en) | 1988-09-01 | 1992-03-03 | Corvita Corporation | Radially expandable endoprosthesis |
| JPH10506560A (ja) | 1995-04-19 | 1998-06-30 | シュナイダー(ユーエスエー)インク | 薬品を放出する被覆されたステント |
| KR100439156B1 (ko) | 2001-07-05 | 2004-07-05 | 주식회사 에스앤지바이오텍 | 약물 방출 스텐트용 코팅 조성물 및 이의 제조 방법 |
| US6921390B2 (en) * | 2001-07-23 | 2005-07-26 | Boston Scientific Scimed, Inc. | Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface |
| US6702850B1 (en) * | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
| US7279174B2 (en) * | 2003-05-08 | 2007-10-09 | Advanced Cardiovascular Systems, Inc. | Stent coatings comprising hydrophilic additives |
| US7807722B2 (en) * | 2003-11-26 | 2010-10-05 | Advanced Cardiovascular Systems, Inc. | Biobeneficial coating compositions and methods of making and using thereof |
| US8309112B2 (en) * | 2003-12-24 | 2012-11-13 | Advanced Cardiovascular Systems, Inc. | Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same |
| US20050220835A1 (en) * | 2004-03-30 | 2005-10-06 | Jayaraman Ramesh B | Agent eluting bioimplantable devices and polymer systems for their preparation |
| WO2006031532A2 (en) * | 2004-09-10 | 2006-03-23 | Surmodics, Inc. | Methods, devices, and coatings for controlled active agent release |
| EP1830902A2 (en) * | 2004-12-30 | 2007-09-12 | Cinvention Ag | Combination comprising an agent providing a signal, an implant material and a drug |
| KR100511618B1 (ko) | 2005-01-17 | 2005-08-31 | 이경범 | 약물방출 조절형 다층 코팅 스텐트 및 이의 제조방법 |
| JP2006262960A (ja) * | 2005-03-22 | 2006-10-05 | Terumo Corp | ステント |
| WO2007127488A1 (en) * | 2006-04-27 | 2007-11-08 | Shenoy Narmada R | Compositions and methods for treating or preventing diseases of body passageways |
-
2008
- 2008-05-23 AU AU2008202283A patent/AU2008202283B2/en not_active Ceased
- 2008-05-28 US US12/154,864 patent/US8017143B2/en not_active Expired - Fee Related
- 2008-05-29 JP JP2008141675A patent/JP5006261B2/ja not_active Expired - Fee Related
- 2008-05-30 CA CA 2632891 patent/CA2632891A1/en not_active Abandoned
- 2008-05-30 EP EP10166708A patent/EP2238993A3/en not_active Ceased
- 2008-05-30 EP EP20080251892 patent/EP2005980A3/en not_active Withdrawn
- 2008-06-02 BR BRPI0801740-9A patent/BRPI0801740A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2005980A3 (en) | 2009-07-08 |
| CA2632891A1 (en) | 2008-12-01 |
| EP2238993A3 (en) | 2010-10-20 |
| US8017143B2 (en) | 2011-09-13 |
| AU2008202283B2 (en) | 2011-01-20 |
| EP2238993A2 (en) | 2010-10-13 |
| AU2008202283A1 (en) | 2008-12-18 |
| JP5006261B2 (ja) | 2012-08-22 |
| EP2005980A2 (en) | 2008-12-24 |
| JP2008296021A (ja) | 2008-12-11 |
| US20080300296A1 (en) | 2008-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B03A | Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2310 DE 14-04-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |