BRPI0806911A8 - Método para influenciar e/ou detectar partículas magnéticas em uma região de ação, partículas magnéticas, e, uso das mesmas - Google Patents

Método para influenciar e/ou detectar partículas magnéticas em uma região de ação, partículas magnéticas, e, uso das mesmas

Info

Publication number
BRPI0806911A8
BRPI0806911A8 BRPI0806911A BRPI0806911A BRPI0806911A8 BR PI0806911 A8 BRPI0806911 A8 BR PI0806911A8 BR PI0806911 A BRPI0806911 A BR PI0806911A BR PI0806911 A BRPI0806911 A BR PI0806911A BR PI0806911 A8 BRPI0806911 A8 BR PI0806911A8
Authority
BR
Brazil
Prior art keywords
region
magnetic particles
action
magnetic
magnetization
Prior art date
Application number
BRPI0806911A
Other languages
English (en)
Inventor
M B Boeve Hans
Markov Dennis
Original Assignee
Koninklijke Philips Electonics N V
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electonics N V, Koninklijke Philips Nv filed Critical Koninklijke Philips Electonics N V
Publication of BRPI0806911A2 publication Critical patent/BRPI0806911A2/pt
Publication of BRPI0806911A8 publication Critical patent/BRPI0806911A8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/0515Magnetic particle imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1866Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle the nanoparticle having a (super)(para)magnetic core coated or functionalised with a peptide, e.g. protein, polyamino acid
    • A61K49/1869Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle the nanoparticle having a (super)(para)magnetic core coated or functionalised with a peptide, e.g. protein, polyamino acid coated or functionalised with a protein being an albumin, e.g. HSA, BSA, ovalbumin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/12Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials
    • H01F1/34Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites
    • H01F1/342Oxides
    • H01F1/344Ferrites, e.g. having a cubic spinel structure (X2+O)(Y23+O3), e.g. magnetite Fe3O4

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Power Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Soft Magnetic Materials (AREA)
  • Magnetic Treatment Devices (AREA)
  • Measuring Magnetic Variables (AREA)
  • Hard Magnetic Materials (AREA)

Abstract

MÉTODO PARA INFLUENCIAR E/OU DETECTAR PARTÍCULAS MAGNÉTICAS EM UMA REGIÃO DE AÇÃO, PARTÍCULAS MAGNÉTICAS, E, USO DAS MESMAS Um método para influenciar e/ou detectar partículas magnéticas em uma região de ação, partículas magnéticas e o uso de partículas magnéticas é divulgado, o qual método compreende os passos de: - introduzir partículas magnéticas em uma região de ação, - gerar um campo de seleção magnético tendo um padrão no espaço de sua força de campo magnético tal que uma primeira sub-zona tendo uma força de campo magnético são formadas na região de ação, - mudar a posição no espaço da duas sub-zonas na região de ação por meio de um campo de orientação magnético tal que a magnetização das partículas magnéticas muda localmente, - adquirir sinais, cujos sinais dependem da magnetização na região de ação, cuja magnetização é influenciada pela mudança na posição no espaço da primeira e segunda sub-zona, onde as partículas magnéticas compreendem uma região do núcleo e uma região de casca, a região do núcleo compreendendo um material magnético, onde o material magnético da região do núcleo é fornecida como um material principalmente metálico de comparavelmente magnetização de alta saturação, e onde a região da casca compreende principalmente um material de metal óxido ou um material de metal nobre.
BRPI0806911A 2007-01-24 2008-01-18 Método para influenciar e/ou detectar partículas magnéticas em uma região de ação, partículas magnéticas, e, uso das mesmas BRPI0806911A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07101071 2007-01-24
EP07101071.4 2007-01-24
PCT/IB2008/050186 WO2008090500A2 (en) 2007-01-24 2008-01-18 Method for influencing and/or detecting magnetic particles in a region of action, magnetic particles and the use of magnetic particles

Publications (2)

Publication Number Publication Date
BRPI0806911A2 BRPI0806911A2 (pt) 2014-04-29
BRPI0806911A8 true BRPI0806911A8 (pt) 2015-10-13

Family

ID=39493893

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0806911A BRPI0806911A8 (pt) 2007-01-24 2008-01-18 Método para influenciar e/ou detectar partículas magnéticas em uma região de ação, partículas magnéticas, e, uso das mesmas

Country Status (7)

Country Link
US (1) US8354841B2 (pt)
EP (1) EP2124715A2 (pt)
JP (1) JP5404417B2 (pt)
CN (2) CN104042214A (pt)
BR (1) BRPI0806911A8 (pt)
RU (1) RU2481570C2 (pt)
WO (1) WO2008090500A2 (pt)

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EP2231273A2 (en) * 2007-12-13 2010-09-29 Koninklijke Philips Electronics N.V. Arrangement and method for influencing and/or detecting magnetic particles in a region of action
WO2010103419A1 (en) * 2009-03-09 2010-09-16 Koninklijke Philips Electronics N.V. Arrangement and method for measuring a magnetic material in a region of action
KR20140033315A (ko) * 2010-11-15 2014-03-18 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 알라바마 포 앤드 온 비하프 오브 더 유니버시티 오브 알라바마 자기 교환 결합형 코어-셀 나노자석
EP2685273A1 (en) * 2012-07-13 2014-01-15 Université Montpellier 2, Sciences et Techniques Micromagnetometry detection system and method for detecting magnetic signatures of magnetic materials
DE102014226138A1 (de) 2014-12-16 2016-06-16 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum Herstellen einer Vorrichtung mit einer dreidimensionalen magnetischen Struktur
DE102016215617A1 (de) 2016-08-19 2018-02-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum Herstellen eines Hohlraums mit poröser Struktur
DE102016215616B4 (de) * 2016-08-19 2020-02-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum Herstellen einer magnetischen Struktur und Vorrichtung
CN107045111B (zh) * 2017-03-29 2023-10-13 金华职业技术学院 一种用于测量磁性分子团簇的磁矩的磁强计
US11077313B2 (en) * 2017-07-07 2021-08-03 Weinberg Medical Physics Inc Electricity energy harvesting with liquid crystal-magnetic particle composite particles
CN112326776B (zh) * 2020-10-30 2023-10-17 北京航空航天大学 P140靶向光学-磁性粒子成像细胞特异性融合装置
KR102583310B1 (ko) * 2021-12-29 2023-09-26 브이메이커(주) 광대역 반사 및 흡수를 갖는 전자기파 차폐소재 및 그 제조방법
CN115144303B (zh) * 2022-08-01 2025-05-16 中国科学院自动化研究所 基于磁粒子布朗弛豫的细胞质粘度检测方法及应用

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Also Published As

Publication number Publication date
US20100123456A1 (en) 2010-05-20
BRPI0806911A2 (pt) 2014-04-29
EP2124715A2 (en) 2009-12-02
US8354841B2 (en) 2013-01-15
RU2009131746A (ru) 2011-02-27
RU2481570C2 (ru) 2013-05-10
JP5404417B2 (ja) 2014-01-29
JP2010517287A (ja) 2010-05-20
WO2008090500A3 (en) 2008-09-12
WO2008090500A2 (en) 2008-07-31
CN101600389A (zh) 2009-12-09
CN104042214A (zh) 2014-09-17

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Owner name: KONINKLIJKE PHILIPS N.V. (NL)

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Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2497 DE 13-11-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.