BRPI0807177B8 - dispositivo de enxerto de tecido tubular e método de preparação do mesmo - Google Patents

dispositivo de enxerto de tecido tubular e método de preparação do mesmo

Info

Publication number
BRPI0807177B8
BRPI0807177B8 BRPI0807177A BRPI0807177A BRPI0807177B8 BR PI0807177 B8 BRPI0807177 B8 BR PI0807177B8 BR PI0807177 A BRPI0807177 A BR PI0807177A BR PI0807177 A BRPI0807177 A BR PI0807177A BR PI0807177 B8 BRPI0807177 B8 BR PI0807177B8
Authority
BR
Brazil
Prior art keywords
tubular tissue
tubular
vein
graft device
matrix
Prior art date
Application number
BRPI0807177A
Other languages
English (en)
Inventor
Mohammed El-Kurdi
Yi Hong
Lorenzo Soletti
John J Stankus
David A Vorp
William R Wagner
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of BRPI0807177A2 publication Critical patent/BRPI0807177A2/pt
Publication of BRPI0807177B1 publication Critical patent/BRPI0807177B1/pt
Publication of BRPI0807177B8 publication Critical patent/BRPI0807177B8/pt

Links

Classifications

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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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  • General Engineering & Computer Science (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Polymers & Plastics (AREA)

Abstract

dispositivo de enxerto de tecido tubular e métodos de preparação do mesmo e de bypass cardíaco. é proporcionado um dispositivo de enxerto de tecido tubular que compreende um tecido tubular e uma matriz de fibra restritiva de um polímero bioerodível sobre uma circunferência do tecido tubular. a matriz pode ser electrospun sobre o tecido tubular. numa modalidade, o tecido tubular é de uma veia, tal como uma veia safena, útil como um enxerto arterial, por exemplo e sem limitação, num procedimento de bypass da artéria coronária. também é proporcionado um método de preparação de um enxerto tubular que compreende depositar uma matriz de fibra de um polímero bioerodível sobre um perímetro de um tecido tubular para produzir um dispositivo de enxerto de tecido tubular. e também proporcionado um método de bypass cardíaco que compreende bypassar uma artéria coronária com um dispositivo de enxerto de tecido tubular compreendendo uma veia ¢ uma matriz de fibra restritiva de um polímero bioerodível sobre uma circunferência da veia.
BRPI0807177A 2007-01-30 2008-01-30 dispositivo de enxerto de tecido tubular e método de preparação do mesmo BRPI0807177B8 (pt)

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US89835607P 2007-01-30 2007-01-30
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Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7998188B2 (en) 2003-04-28 2011-08-16 Kips Bay Medical, Inc. Compliant blood vessel graft
GB0515140D0 (en) * 2005-07-22 2005-08-31 Ark Therapeutics Ltd Therapeutic device
US20080109070A1 (en) * 2006-08-10 2008-05-08 Wagner William R Biodegradable elastomeric scaffolds containing microintegrated cells
BRPI0807177B8 (pt) 2007-01-30 2021-06-22 Univ Pittsburgh dispositivo de enxerto de tecido tubular e método de preparação do mesmo
US20100070020A1 (en) * 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
WO2009064442A1 (en) * 2007-11-13 2009-05-22 Brookwood Pharmaceuticals, Inc. Viscous terpolymers as drug delivery platform
US9492593B2 (en) 2008-09-24 2016-11-15 Poly-Med, Inc. Absorbable, permeability-modulated barrier composites and applications thereof
WO2010048281A1 (en) * 2008-10-21 2010-04-29 Emory University Composite biomimetic materials
US8735354B2 (en) * 2008-11-07 2014-05-27 Uab Research Foundation Endothelium mimicking nanomatrix
US8734503B2 (en) * 2008-11-24 2014-05-27 Vascular Graft Solutions Ltd. External stent
US8951546B2 (en) 2008-12-23 2015-02-10 Surmodics Pharmaceuticals, Inc. Flexible implantable composites and implants comprising same
US8974808B2 (en) * 2008-12-23 2015-03-10 Surmodics, Inc. Elastic implantable composites and implants comprising same
US20100158978A1 (en) * 2008-12-23 2010-06-24 Peter Markland Bioactive spray coating compositions and methods of making and uses thereof
US20100168807A1 (en) * 2008-12-23 2010-07-01 Burton Kevin W Bioactive terpolymer compositions and methods of making and using same
US9415197B2 (en) 2008-12-23 2016-08-16 Surmodics, Inc. Implantable suction cup composites and implants comprising same
US20130268062A1 (en) 2012-04-05 2013-10-10 Zeus Industrial Products, Inc. Composite prosthetic devices
PL2384375T3 (pl) 2009-01-16 2017-12-29 Zeus Industrial Products, Inc. Elektrospinning PTFE materiałami o wysokiej lepkości
US8685424B2 (en) 2010-10-14 2014-04-01 Zeus Industrial Products, Inc. Antimicrobial substrate
US8262979B2 (en) 2009-08-07 2012-09-11 Zeus Industrial Products, Inc. Process of making a prosthetic device from electrospun fibers
US10022468B2 (en) * 2009-02-02 2018-07-17 Kimberly-Clark Worldwide, Inc. Absorbent articles containing a multifunctional gel
CA2778459C (en) * 2009-10-28 2016-08-16 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Bioerodible wraps and uses therefor
US8992594B2 (en) 2009-12-16 2015-03-31 Neograft Technologies, Inc. Graft devices and methods of use
US9295541B2 (en) 2009-12-31 2016-03-29 Neograft Technologies, Inc. Graft devices and methods of fabrication
WO2011150328A1 (en) 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
WO2012012407A2 (en) 2010-07-19 2012-01-26 Neograft Technologies, Inc. Graft devices and methods of use
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
WO2012030821A1 (en) 2010-08-30 2012-03-08 Surmodics Pharmaceuticals, Inc. Terpolymer blends and their use as pressure-sensitive adhesives
US9656417B2 (en) 2010-12-29 2017-05-23 Neograft Technologies, Inc. System and method for mandrel-less electrospinning
EP2663265A4 (en) 2011-01-14 2016-05-25 Neograft Technologies Inc APPARATUS FOR GENERATING DEVICES FOR GRAFT
JP6203639B2 (ja) 2011-01-28 2017-09-27 メリット・メディカル・システムズ・インコーポレイテッドＭｅｒｉｔ Ｍｅｄｉｃａｌ Ｓｙｓｔｅｍｓ，Ｉｎｃ． 電界紡糸されたｐｔｆｅでコーティングされたステントおよび使用方法
WO2012109309A2 (en) * 2011-02-09 2012-08-16 Neograft Technologies, Inc. System and mandrel for creating graft devices
US10227568B2 (en) 2011-03-22 2019-03-12 Nanofiber Solutions, Llc Fiber scaffolds for use in esophageal prostheses
US10052218B2 (en) 2011-04-18 2018-08-21 Vascular Graft Solutions Ltd. Devices and methods for deploying implantable sleeves over blood vessels
WO2013016349A2 (en) 2011-07-25 2013-01-31 Neograft Technologies, Inc. Vessel treatment methods and devices for use in a graft device
WO2013025819A2 (en) 2011-08-16 2013-02-21 The University Of Kansas Fibrous tracheal patch
WO2013063190A1 (en) * 2011-10-25 2013-05-02 Neograft Technologies, Inc. Graft device with adhered fiber matrix
WO2013078051A1 (en) 2011-11-21 2013-05-30 Johnson Jed K Fiber scaffolds for use in tracheal prostheses
KR101421579B1 (ko) * 2011-12-02 2014-07-22 경상대학교산학협력단 무정형의 Ｐ（３ＨＶ－ｃｏ－４ＨＢ）－ｂ－ｍＰＥＧ에 약물이 담지된 약물전달 제제
EP2790607B1 (en) 2011-12-13 2017-11-15 Neograft Technologies, Inc. System and atraumatic mandrel for creating graft devices
US9884027B2 (en) 2012-01-12 2018-02-06 Nanofiber Solutions, Inc. Nanofiber scaffolds for biological structures
WO2013109528A1 (en) 2012-01-16 2013-07-25 Merit Medical Systems, Inc. Rotational spun material covered medical appliances and methods of manufacture
JP6117482B2 (ja) * 2012-06-14 2017-04-19 パール工業株式会社 選定分子導入装置
US10507268B2 (en) 2012-09-19 2019-12-17 Merit Medical Systems, Inc. Electrospun material covered medical appliances and methods of manufacture
US9198999B2 (en) 2012-09-21 2015-12-01 Merit Medical Systems, Inc. Drug-eluting rotational spun coatings and methods of use
US20140249618A1 (en) * 2013-02-18 2014-09-04 Elutin, Inc. Site specific drug delivery wraps, systems and methods of use thereof
CN103173931B (zh) * 2013-03-07 2016-04-06 苏州睿研纳米医学科技有限公司 生物相容的纤维复合无纺网毡及其制备方法和应用
EP3988278A1 (en) 2013-03-13 2022-04-27 Merit Medical Systems, Inc. Serially deposited fiber materials and associated devices and methods
WO2014159399A1 (en) 2013-03-13 2014-10-02 Merit Medical Systems, Inc. Methods, systems, and apparatuses for manufacturing rotational spun appliances
EP3950019A1 (en) 2013-03-15 2022-02-09 Nanofiber Solutions, LLC Biocompatible fiber textiles for implantation
US9737632B2 (en) * 2013-09-25 2017-08-22 Nanofiber Solutions, Inc. Fiber scaffolds for use creating implantable structures
US20160325480A1 (en) * 2013-12-31 2016-11-10 Neograft Technologies, Inc. Self-diagnostic graft production systems and related methods
WO2015116912A1 (en) 2014-01-30 2015-08-06 Poly-Med. Inc. Thermally and dimensionally stabilized electrospun compositions and methods of making same
CA2967352A1 (en) * 2014-11-11 2016-05-19 Duke University Compositions and methods for the prevention and/or reduction of scarring
EP3261589B1 (en) 2015-02-26 2020-09-16 Merit Medical Systems, Inc. Layered medical appliances
CZ306213B6 (cs) * 2015-03-06 2016-10-05 Technická univerzita v Liberci Cévní náhrada, zejména maloprůměrová cévní náhrada
US10286116B2 (en) 2015-04-15 2019-05-14 Mayo Foundation For Medical Education And Research Methods and materials for reducing venous neointimal hyperplasia of an arteriovenous fistula or graft
EP4331632A3 (en) * 2015-04-29 2024-05-29 NFS IP Holdings, LLC Multi-component electrospun fiber scaffolds
WO2017079328A1 (en) 2015-11-02 2017-05-11 Nanofiber Solutions, Inc. Electrospun fibers having contrast agents and methods of making the same
WO2018144858A1 (en) 2017-02-02 2018-08-09 Nanofiber Solutions, Inc. Methods of improving bone-soft tissue healing using electrospun fibers
JP7477138B2 (ja) * 2017-05-16 2024-05-01 コーネル ユニバーシティー グラフェン繊維、糸、複合体、およびそれらの製造方法
BR102017013337A2 (pt) * 2017-06-20 2019-01-15 Fundação Ezequiel Dias dispositivo de liberação ocular de fármacos, nanofibras poliméricas contendo bevacizumabe e processo de obtenção
US11529318B2 (en) * 2017-06-23 2022-12-20 University of Pittsburgh—of the Commonwealth System of Higher Education Devices and methods for local delivery of tacrolimus
CN107630292B (zh) * 2017-09-18 2019-04-30 吉林大学 一种负载亚精胺的生物活性膜及其静电纺丝制备方法
WO2019079195A1 (en) 2017-10-16 2019-04-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education GENETICALLY MODIFIED MESENCHYMAL STEM CELLS FOR USE IN CARDIOVASCULAR PROSTHESES
CN107941760B (zh) * 2017-11-16 2020-06-30 南方医科大学南方医院 直肠癌切除标本的切缘处胶原组织评价方法
WO2019165185A1 (en) 2018-02-22 2019-08-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracts for the regeneration of ligaments
US20210023267A1 (en) * 2018-04-02 2021-01-28 Bioaesthetics Corporation Polymer-permeated grafts and methods of making and using the same
US20210236260A1 (en) * 2018-04-30 2021-08-05 Board Of Regents Of The University Of Nebraska Stent-graft
WO2020072717A1 (en) 2018-10-05 2020-04-09 Board Of Regents Of The University Of Nebraska Bypass graft
CN109498839A (zh) * 2018-11-13 2019-03-22 南开大学 一种生物复合人工血管和应用
AU2019397470A1 (en) 2018-12-11 2021-06-10 Nfs Ip Holdings, Llc Methods of treating chronic wounds using electrospun fibers
CN110274807B (zh) * 2019-06-27 2021-07-30 浙江省海洋水产养殖研究所 一种南美白对虾性腺组织冷冻切片的制作方法
CN110629321B (zh) * 2019-09-17 2021-10-12 南通大学 一种抗凝血溶纤纳米纤维材料的制备方法
BR112022006037A2 (pt) * 2019-10-03 2022-07-12 Bioaesthetics Corp Enxertos permeados por polímero e métodos de produção e uso dos mesmos
DE102019132938A1 (de) * 2019-12-04 2021-06-10 Cortronik GmbH Verfahren zur Herstellung einer intraluminalen Endoprothese mit einer biodegradierbaren Hülle
US12310836B2 (en) 2020-03-03 2025-05-27 Akeo Hagiwara Vein cover
EP4115915A4 (en) 2020-03-03 2024-04-03 Akeo Hagiwara Vein cover
CN112885216B (zh) * 2021-01-28 2022-07-08 山西白求恩医院(山西医学科学院) 一种医学教育实训用静脉注射训练装置
WO2022183215A1 (en) 2021-02-26 2022-09-01 Merit Medical Systems, Inc. Fibrous constructs with therapeutic material particles
KR20250116484A (ko) * 2024-01-25 2025-08-01 순천향대학교 산학협력단 내막과증식 예방을 위한 코어-쉘 구조 나노섬유체로 구성된 중, 소구경 인공혈관

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609626A (en) * 1989-05-31 1997-03-11 Baxter International Inc. Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts
US5723004A (en) 1993-10-21 1998-03-03 Corvita Corporation Expandable supportive endoluminal grafts
JP2719752B2 (ja) 1994-03-24 1998-02-25 パイロットプレシジョン株式会社 接ぎ木方法及び台木と穂木とを接合するための棒状部材の供給装置
US20030086975A1 (en) 2001-11-08 2003-05-08 Timothy Ringeisen Method for making a porous Polymeric material
US6036702A (en) 1997-04-23 2000-03-14 Vascular Science Inc. Medical grafting connectors and fasteners
US6187038B1 (en) 1998-04-08 2001-02-13 Sulzer Carbomedics Inc. Small bore biologic graft with therapeutic delivery system
US6113612A (en) 1998-11-06 2000-09-05 St. Jude Medical Cardiovascular Group, Inc. Medical anastomosis apparatus
EP1126795A2 (en) 1998-11-06 2001-08-29 St. Jude Medical Cardiovascular Group, Inc. Medical graft connector component and methods of making and installing same
US6296863B1 (en) 1998-11-23 2001-10-02 Agion Technologies, Llc Antimicrobial fabric and medical graft of the fabric
US20020081732A1 (en) * 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
EP1263484B1 (en) 2000-03-15 2007-05-16 OrbusNeich Medical, Inc. Coating which promotes endothelial cell adherence
AU2001288692A1 (en) * 2000-09-01 2002-03-13 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed fibrin-based matrices and tissues
WO2002074190A2 (en) * 2001-03-20 2002-09-26 Nicast Ltd. Polymer fiber tubular structure having improved kinking resistance
US6599323B2 (en) 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US20020123786A1 (en) 2001-03-02 2002-09-05 Ventrica, Inc. Methods and devices for bypassing an obstructed target vessel by placing the vessel in communication with a heart chamber containing blood
US6713011B2 (en) 2001-05-16 2004-03-30 The Research Foundation At State University Of New York Apparatus and methods for electrospinning polymeric fibers and membranes
US6891077B2 (en) * 2001-07-25 2005-05-10 The United States Of America As Represented By The Secretary Of The Army Fibrinogen bandages and arterial bleeding models and methods of making and using thereof
US20040146546A1 (en) * 2002-09-26 2004-07-29 Angiotech Pharmaceuticals, Inc. Perivascular wraps
EP1555957A4 (en) * 2002-10-04 2010-11-24 Nanomatrix Inc SEALANT FOR SKIN AND OTHER FABRICS
EP1415671A1 (en) * 2002-11-01 2004-05-06 Polyganics B.V. Biodegradable drains for medical applications
CA2417634A1 (en) 2002-11-22 2004-05-22 Emory University Plastic and elastic protein copolymers
US7452374B2 (en) 2003-04-24 2008-11-18 Maquet Cardiovascular, Llc AV grafts with rapid post-operative self-sealing capabilities
US7998188B2 (en) * 2003-04-28 2011-08-16 Kips Bay Medical, Inc. Compliant blood vessel graft
CA2523812C (en) 2003-04-28 2011-06-21 Medtronic, Inc. Compliant venous graft
US7001401B1 (en) * 2003-05-06 2006-02-21 Medcanica Llc Device and method for holding a blood vessel
AU2004251680B2 (en) 2003-06-04 2010-02-18 Georgetown University Method for improving stability and shelf-life of liposome complexes
CN1251769C (zh) 2003-08-29 2006-04-19 中国人民解放军第三军医大学 基因修饰的组织工程血管
EP1719538B1 (en) 2004-02-27 2015-09-30 Sumitomo Electric Industries, Ltd. Composite structure and process for producing the same
US7775965B2 (en) 2004-03-09 2010-08-17 The Board Of Regents Of The University Of Oklahoma Decellularized grafts from umbilical cord vessels and process for preparing and using same
US20060085063A1 (en) * 2004-10-15 2006-04-20 Shastri V P Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
US7759120B2 (en) 2005-03-02 2010-07-20 Kps Bay Medical, Inc. Seeding implantable medical devices with cells
US20060199265A1 (en) 2005-03-02 2006-09-07 Wolf Michael F Seeding implantable medical devices with cells
US7531503B2 (en) * 2005-03-11 2009-05-12 Wake Forest University Health Sciences Cell scaffold matrices with incorporated therapeutic agents
EP1863547B1 (en) * 2005-03-11 2016-05-11 Wake Forest University Health Sciences Tissue engineered blood vessels
US20070239267A1 (en) 2006-03-28 2007-10-11 Medtronic Vascular, Inc. Stent Graft With Healing Promoting Necks
BRPI0807177B8 (pt) 2007-01-30 2021-06-22 Univ Pittsburgh dispositivo de enxerto de tecido tubular e método de preparação do mesmo
KR100932688B1 (ko) 2007-07-06 2009-12-21 한국과학기술연구원 인공혈관용 이중막 구조의 튜브형 다공성 스캐폴드 및 그의제조방법
WO2009086458A1 (en) 2007-12-27 2009-07-09 C.R. Bard. Inc. Vascular graft prosthesis having a reinforced margin for enhanced anastomosis
US8353814B2 (en) 2008-10-09 2013-01-15 Kips Bay Medical, Inc. Apparatus and method for mounting an external scaffold to a vascular graft

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JP5973121B2 (ja) 2016-08-23
AU2008210523B2 (en) 2013-08-22
US9333068B2 (en) 2016-05-10
CN105343932A (zh) 2016-02-24
US9237945B2 (en) 2016-01-19
CN101663001A (zh) 2010-03-03
KR101719081B1 (ko) 2017-03-22
CN114377204A (zh) 2022-04-22
CA2677033C (en) 2015-04-28
AU2008210523A1 (en) 2008-08-07
EP2111185A4 (en) 2012-11-14
US20160317280A1 (en) 2016-11-03
WO2008094971A3 (en) 2008-10-16
WO2008094971A2 (en) 2008-08-07
CA2677033A1 (en) 2008-08-07
KR20090113318A (ko) 2009-10-29
US20080208323A1 (en) 2008-08-28
KR20150067388A (ko) 2015-06-17
EP2111185B1 (en) 2017-12-20
JP5950966B2 (ja) 2016-07-13
BRPI0807177B1 (pt) 2020-06-30
US20150150673A1 (en) 2015-06-04
EP2111185A2 (en) 2009-10-28
JP2014221394A (ja) 2014-11-27
BRPI0807177A2 (pt) 2014-05-27

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