BRPI0807177B8 - dispositivo de enxerto de tecido tubular e método de preparação do mesmo - Google Patents

dispositivo de enxerto de tecido tubular e método de preparação do mesmo

Info

Publication number
BRPI0807177B8
BRPI0807177B8 BRPI0807177A BRPI0807177A BRPI0807177B8 BR PI0807177 B8 BRPI0807177 B8 BR PI0807177B8 BR PI0807177 A BRPI0807177 A BR PI0807177A BR PI0807177 A BRPI0807177 A BR PI0807177A BR PI0807177 B8 BRPI0807177 B8 BR PI0807177B8
Authority
BR
Brazil
Prior art keywords
tubular tissue
tubular
vein
graft device
matrix
Prior art date
Application number
BRPI0807177A
Other languages
English (en)
Inventor
Mohammed El-Kurdi
Yi Hong
Lorenzo Soletti
John J Stankus
David A Vorp
William R Wagner
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of BRPI0807177A2 publication Critical patent/BRPI0807177A2/pt
Publication of BRPI0807177B1 publication Critical patent/BRPI0807177B1/pt
Publication of BRPI0807177B8 publication Critical patent/BRPI0807177B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3679—Hollow organs, e.g. bladder, esophagus, urether, uterus, intestine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3826—Muscle cells, e.g. smooth muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D01D5/0076—Electro-spinning characterised by the electro-spinning apparatus characterised by the collecting device, e.g. drum, wheel, endless belt, plate or grid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/22—Materials or treatment for tissue regeneration for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/10—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyurethanes
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/12—Physical properties biodegradable
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2509/00—Medical; Hygiene
    • D10B2509/06—Vascular grafts; stents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Textile Engineering (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Polymers & Plastics (AREA)

Abstract

dispositivo de enxerto de tecido tubular e métodos de preparação do mesmo e de bypass cardíaco. é proporcionado um dispositivo de enxerto de tecido tubular que compreende um tecido tubular e uma matriz de fibra restritiva de um polímero bioerodível sobre uma circunferência do tecido tubular. a matriz pode ser electrospun sobre o tecido tubular. numa modalidade, o tecido tubular é de uma veia, tal como uma veia safena, útil como um enxerto arterial, por exemplo e sem limitação, num procedimento de bypass da artéria coronária. também é proporcionado um método de preparação de um enxerto tubular que compreende depositar uma matriz de fibra de um polímero bioerodível sobre um perímetro de um tecido tubular para produzir um dispositivo de enxerto de tecido tubular. e também proporcionado um método de bypass cardíaco que compreende bypassar uma artéria coronária com um dispositivo de enxerto de tecido tubular compreendendo uma veia ¢ uma matriz de fibra restritiva de um polímero bioerodível sobre uma circunferência da veia.
BRPI0807177A 2007-01-30 2008-01-30 dispositivo de enxerto de tecido tubular e método de preparação do mesmo BRPI0807177B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89835607P 2007-01-30 2007-01-30
US60/898.356 2007-01-30
PCT/US2008/052408 WO2008094971A2 (en) 2007-01-30 2008-01-30 Bioerodible wraps and uses therefor

Publications (3)

Publication Number Publication Date
BRPI0807177A2 BRPI0807177A2 (pt) 2014-05-27
BRPI0807177B1 BRPI0807177B1 (pt) 2020-06-30
BRPI0807177B8 true BRPI0807177B8 (pt) 2021-06-22

Family

ID=39674763

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807177A BRPI0807177B8 (pt) 2007-01-30 2008-01-30 dispositivo de enxerto de tecido tubular e método de preparação do mesmo

Country Status (9)

Country Link
US (3) US9237945B2 (pt)
EP (1) EP2111185B1 (pt)
JP (2) JP5973121B2 (pt)
KR (2) KR101719081B1 (pt)
CN (3) CN105343932A (pt)
AU (1) AU2008210523B2 (pt)
BR (1) BRPI0807177B8 (pt)
CA (1) CA2677033C (pt)
WO (1) WO2008094971A2 (pt)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7998188B2 (en) 2003-04-28 2011-08-16 Kips Bay Medical, Inc. Compliant blood vessel graft
GB0515140D0 (en) * 2005-07-22 2005-08-31 Ark Therapeutics Ltd Therapeutic device
WO2008024640A2 (en) * 2006-08-10 2008-02-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biodegradable elastomeric scaffolds containing microintegrated cells
BRPI0807177B8 (pt) 2007-01-30 2021-06-22 Univ Pittsburgh dispositivo de enxerto de tecido tubular e método de preparação do mesmo
US20100070020A1 (en) 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
US9090737B2 (en) * 2007-11-13 2015-07-28 Surmodics, Inc. Viscous terpolymers as drug delivery platform
US9492593B2 (en) 2008-09-24 2016-11-15 Poly-Med, Inc. Absorbable, permeability-modulated barrier composites and applications thereof
WO2010048281A1 (en) * 2008-10-21 2010-04-29 Emory University Composite biomimetic materials
US8735354B2 (en) * 2008-11-07 2014-05-27 Uab Research Foundation Endothelium mimicking nanomatrix
EP2361059B1 (en) 2008-11-24 2014-05-14 Vascular Graft Solutions Ltd. External stent
US8974808B2 (en) * 2008-12-23 2015-03-10 Surmodics, Inc. Elastic implantable composites and implants comprising same
US8951546B2 (en) 2008-12-23 2015-02-10 Surmodics Pharmaceuticals, Inc. Flexible implantable composites and implants comprising same
US20100168807A1 (en) * 2008-12-23 2010-07-01 Burton Kevin W Bioactive terpolymer compositions and methods of making and using same
US20100158978A1 (en) * 2008-12-23 2010-06-24 Peter Markland Bioactive spray coating compositions and methods of making and uses thereof
US9415197B2 (en) 2008-12-23 2016-08-16 Surmodics, Inc. Implantable suction cup composites and implants comprising same
CN102282301B (zh) 2009-01-16 2014-07-30 Zeus工业品公司 利用高粘度材料对ptfe进行电纺丝
US8257640B2 (en) 2009-08-07 2012-09-04 Zeus Industrial Products, Inc. Multilayered composite structure with electrospun layer
US20130268062A1 (en) 2012-04-05 2013-10-10 Zeus Industrial Products, Inc. Composite prosthetic devices
US8685424B2 (en) 2010-10-14 2014-04-01 Zeus Industrial Products, Inc. Antimicrobial substrate
US10022468B2 (en) * 2009-02-02 2018-07-17 Kimberly-Clark Worldwide, Inc. Absorbent articles containing a multifunctional gel
JP2013509258A (ja) * 2009-10-28 2013-03-14 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 生体浸食性ラップおよびそのための使用
EP2512369B8 (en) 2009-12-16 2017-05-17 Neograft Technologies, Inc. Graft devices and methods of use
CA2785989A1 (en) 2009-12-31 2011-07-07 Neograft Technologies, Inc. Graft devices and methods of fabrication
WO2011150328A1 (en) 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
EP2595695B1 (en) 2010-07-19 2019-02-06 Neograft Technologies, Inc. Graft devices and methods of use
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
CA2809825A1 (en) 2010-08-30 2012-03-08 Surmodics Pharmaceuticals, Inc. Biodegradable terpolymers and terpolymer blends as pressure-sensitive adhesives
US9656417B2 (en) 2010-12-29 2017-05-23 Neograft Technologies, Inc. System and method for mandrel-less electrospinning
US10085829B2 (en) 2011-01-14 2018-10-02 Neograft Technologies, Inc. Apparatus for creating graft devices
EP2667829B1 (en) 2011-01-28 2021-09-22 Merit Medical Systems, Inc. Electrospun ptfe coated stent and method of use
US9867690B2 (en) 2011-02-09 2018-01-16 Neograft Technologies, Inc. System and mandrel for creating graft devices
US10227568B2 (en) 2011-03-22 2019-03-12 Nanofiber Solutions, Llc Fiber scaffolds for use in esophageal prostheses
WO2012143925A1 (en) 2011-04-18 2012-10-26 Vascular Graft Solutions Ltd Devices and methods for deploying implantable sleeves over blood vessels
WO2013016349A2 (en) 2011-07-25 2013-01-31 Neograft Technologies, Inc. Vessel treatment methods and devices for use in a graft device
WO2013025819A2 (en) 2011-08-16 2013-02-21 The University Of Kansas Fibrous tracheal patch
US20140288632A1 (en) * 2011-10-25 2014-09-25 Neograft Technologies, Inc. Graft Device with Adhered Fiber Matrix
US10239262B2 (en) 2011-11-21 2019-03-26 Nanofiber Solutions, Llc Fiber scaffolds for use in tracheal prostheses
KR101421579B1 (ko) * 2011-12-02 2014-07-22 경상대학교산학협력단 무정형의 Ｐ（３ＨＶ－ｃｏ－４ＨＢ）－ｂ－ｍＰＥＧ에 약물이 담지된 약물전달 제제
EP2790607B1 (en) 2011-12-13 2017-11-15 Neograft Technologies, Inc. System and atraumatic mandrel for creating graft devices
WO2013106822A1 (en) 2012-01-12 2013-07-18 Johnson Jed K Nanofiber scaffolds for biological structures
CN110064076A (zh) 2012-01-16 2019-07-30 麦瑞通医疗设备有限公司 被旋转纺丝材料覆盖的医疗器械和制造方法
JP6117482B2 (ja) * 2012-06-14 2017-04-19 パール工業株式会社 選定分子導入装置
US10507268B2 (en) 2012-09-19 2019-12-17 Merit Medical Systems, Inc. Electrospun material covered medical appliances and methods of manufacture
US9198999B2 (en) 2012-09-21 2015-12-01 Merit Medical Systems, Inc. Drug-eluting rotational spun coatings and methods of use
WO2014127278A2 (en) * 2013-02-18 2014-08-21 Elutin, Inc. Site specific drug delivery wraps, systems and methods of use thereof
CN103173931B (zh) * 2013-03-07 2016-04-06 苏州睿研纳米医学科技有限公司 生物相容的纤维复合无纺网毡及其制备方法和应用
WO2014159710A1 (en) 2013-03-13 2014-10-02 Merit Medical Systems, Inc. Serially deposited fiber materials and associated devices and methods
WO2014159399A1 (en) 2013-03-13 2014-10-02 Merit Medical Systems, Inc. Methods, systems, and apparatuses for manufacturing rotational spun appliances
EP3950019A1 (en) 2013-03-15 2022-02-09 Nanofiber Solutions, LLC Biocompatible fiber textiles for implantation
WO2015048224A1 (en) * 2013-09-25 2015-04-02 Johnson Jed K Fiber scaffolds for use creating implantable structures
US20160325480A1 (en) * 2013-12-31 2016-11-10 Neograft Technologies, Inc. Self-diagnostic graft production systems and related methods
US11891727B2 (en) 2014-01-30 2024-02-06 Poly-Med, Inc. Thermally and dimensionally stabilized electrospun compositions and methods of making same
US20170304488A1 (en) * 2014-11-11 2017-10-26 Duke University Compositions and Methods for the Prevention and/or Reduction of Scarring
EP3785677B1 (en) 2015-02-26 2024-08-07 Merit Medical Systems, Inc. Layered medical appliances
CZ306213B6 (cs) * 2015-03-06 2016-10-05 Technická univerzita v Liberci Cévní náhrada, zejména maloprůměrová cévní náhrada
US10286116B2 (en) * 2015-04-15 2019-05-14 Mayo Foundation For Medical Education And Research Methods and materials for reducing venous neointimal hyperplasia of an arteriovenous fistula or graft
US20160317706A1 (en) * 2015-04-29 2016-11-03 Nanofiber Solutions, Inc. Multi-component electrospun fiber scaffolds
EP3370788A4 (en) 2015-11-02 2019-07-31 Nanofiber Solutions, LLC ELECTRO-spun fibers with contrast agents and method for producing same
WO2018144858A1 (en) 2017-02-02 2018-08-09 Nanofiber Solutions, Inc. Methods of improving bone-soft tissue healing using electrospun fibers
KR102618130B1 (ko) * 2017-05-16 2023-12-27 코넬 유니버시티 그래핀계 섬유, 얀, 복합체, 및 이들의 제조방법
BR102017013337A2 (pt) * 2017-06-20 2019-01-15 Fundação Ezequiel Dias dispositivo de liberação ocular de fármacos, nanofibras poliméricas contendo bevacizumabe e processo de obtenção
US11529318B2 (en) * 2017-06-23 2022-12-20 University of Pittsburgh—of the Commonwealth System of Higher Education Devices and methods for local delivery of tacrolimus
CN107630292B (zh) * 2017-09-18 2019-04-30 吉林大学 一种负载亚精胺的生物活性膜及其静电纺丝制备方法
WO2019079195A1 (en) 2017-10-16 2019-04-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education GENETICALLY MODIFIED MESENCHYMAL STEM CELLS FOR USE IN CARDIOVASCULAR PROSTHESES
CN107941760B (zh) * 2017-11-16 2020-06-30 南方医科大学南方医院 直肠癌切除标本的切缘处胶原组织评价方法
EP3755267B1 (en) 2018-02-22 2024-06-12 University of Pittsburgh - of the Commonwealth System of Higher Education Extracts for the regeneration of ligaments
EP3773769A4 (en) * 2018-04-02 2022-01-19 Bioaesthetics Corporation Polymer-permeated grafts and methods of making and using the same
EP3787554A4 (en) * 2018-04-30 2021-06-16 Board of Regents of the University of Nebraska STENT TRANSPLANT
WO2020072717A1 (en) * 2018-10-05 2020-04-09 Board Of Regents Of The University Of Nebraska Bypass graft
CN109498839A (zh) * 2018-11-13 2019-03-22 南开大学 一种生物复合人工血管和应用
US11576927B2 (en) 2018-12-11 2023-02-14 Nanofiber Solutions, Llc Methods of treating chronic wounds using electrospun fibers
CN110274807B (zh) * 2019-06-27 2021-07-30 浙江省海洋水产养殖研究所 一种南美白对虾性腺组织冷冻切片的制作方法
CN110629321B (zh) * 2019-09-17 2021-10-12 南通大学 一种抗凝血溶纤纳米纤维材料的制备方法
BR112022006037A2 (pt) * 2019-10-03 2022-07-12 Bioaesthetics Corp Enxertos permeados por polímero e métodos de produção e uso dos mesmos
DE102019132938A1 (de) * 2019-12-04 2021-06-10 Cortronik GmbH Verfahren zur Herstellung einer intraluminalen Endoprothese mit einer biodegradierbaren Hülle
JP7624235B2 (ja) 2020-03-03 2025-01-30 株式会社彩 静脈カバー
US12310836B2 (en) 2020-03-03 2025-05-27 Akeo Hagiwara Vein cover
CN112885216B (zh) * 2021-01-28 2022-07-08 山西白求恩医院(山西医学科学院) 一种医学教育实训用静脉注射训练装置
WO2022183215A1 (en) 2021-02-26 2022-09-01 Merit Medical Systems, Inc. Fibrous constructs with therapeutic material particles
KR20250116484A (ko) * 2024-01-25 2025-08-01 순천향대학교 산학협력단 내막과증식 예방을 위한 코어-쉘 구조 나노섬유체로 구성된 중, 소구경 인공혈관

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609626A (en) * 1989-05-31 1997-03-11 Baxter International Inc. Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts
US5723004A (en) * 1993-10-21 1998-03-03 Corvita Corporation Expandable supportive endoluminal grafts
JP2719752B2 (ja) * 1994-03-24 1998-02-25 パイロットプレシジョン株式会社 接ぎ木方法及び台木と穂木とを接合するための棒状部材の供給装置
US20030086975A1 (en) * 2001-11-08 2003-05-08 Timothy Ringeisen Method for making a porous Polymeric material
US6036702A (en) * 1997-04-23 2000-03-14 Vascular Science Inc. Medical grafting connectors and fasteners
US6187038B1 (en) * 1998-04-08 2001-02-13 Sulzer Carbomedics Inc. Small bore biologic graft with therapeutic delivery system
US6113612A (en) * 1998-11-06 2000-09-05 St. Jude Medical Cardiovascular Group, Inc. Medical anastomosis apparatus
WO2000027310A2 (en) * 1998-11-06 2000-05-18 St. Jude Medical Cardiovascular Group, Inc. Medical graft connector component and methods of making and installing same
US6296863B1 (en) * 1998-11-23 2001-10-02 Agion Technologies, Llc Antimicrobial fabric and medical graft of the fabric
US20020081732A1 (en) * 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
JP5859179B2 (ja) * 2000-03-15 2016-02-10 オーバスネイチ メディカル、インコーポレイテッド 内皮細胞接着を促進するコーティング
CA2457162A1 (en) * 2000-09-01 2002-03-07 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed fibrin-based matrices and tissues
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US20020123786A1 (en) * 2001-03-02 2002-09-05 Ventrica, Inc. Methods and devices for bypassing an obstructed target vessel by placing the vessel in communication with a heart chamber containing blood
EP1377421A4 (en) * 2001-03-20 2004-05-26 Nicast Ltd TUBULAR POLYMER FIBER STRUCTURE WITH IMPROVED KINK RESISTANCE
US6713011B2 (en) 2001-05-16 2004-03-30 The Research Foundation At State University Of New York Apparatus and methods for electrospinning polymeric fibers and membranes
US6891077B2 (en) * 2001-07-25 2005-05-10 The United States Of America As Represented By The Secretary Of The Army Fibrinogen bandages and arterial bleeding models and methods of making and using thereof
JP2006515186A (ja) * 2002-09-26 2006-05-25 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 血管周囲ラップ
US20070225631A1 (en) * 2002-10-04 2007-09-27 Bowlin Gary L Sealants for Skin and Other Tissues
EP1415671A1 (en) * 2002-11-01 2004-05-06 Polyganics B.V. Biodegradable drains for medical applications
CA2417634A1 (en) * 2002-11-22 2004-05-22 Emory University Plastic and elastic protein copolymers
US7452374B2 (en) * 2003-04-24 2008-11-18 Maquet Cardiovascular, Llc AV grafts with rapid post-operative self-sealing capabilities
US7998188B2 (en) * 2003-04-28 2011-08-16 Kips Bay Medical, Inc. Compliant blood vessel graft
JP4692902B2 (ja) * 2003-04-28 2011-06-01 キップス・ベイ・メディカル・インコーポレーテッド 柔軟な静脈移植体
US7001401B1 (en) * 2003-05-06 2006-02-21 Medcanica Llc Device and method for holding a blood vessel
JP4987474B2 (ja) 2003-06-04 2012-07-25 ジョージタウン・ユニバーシティ リポソーム複合体の安定性および使用期限を改良するための方法
CN1251769C (zh) 2003-08-29 2006-04-19 中国人民解放军第三军医大学 基因修饰的组织工程血管
WO2005082448A1 (ja) * 2004-02-27 2005-09-09 Sumitomo Electric Industries, Ltd. 複合構造体とその製造方法
US7775965B2 (en) 2004-03-09 2010-08-17 The Board Of Regents Of The University Of Oklahoma Decellularized grafts from umbilical cord vessels and process for preparing and using same
US20060085063A1 (en) * 2004-10-15 2006-04-20 Shastri V P Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
US20060199265A1 (en) * 2005-03-02 2006-09-07 Wolf Michael F Seeding implantable medical devices with cells
US7759120B2 (en) * 2005-03-02 2010-07-20 Kps Bay Medical, Inc. Seeding implantable medical devices with cells
JP5232636B2 (ja) * 2005-03-11 2013-07-10 ウエイク・フオレスト・ユニバーシテイ・ヘルス・サイエンシズ 組織の工作された血管
US7531503B2 (en) * 2005-03-11 2009-05-12 Wake Forest University Health Sciences Cell scaffold matrices with incorporated therapeutic agents
US20070239267A1 (en) * 2006-03-28 2007-10-11 Medtronic Vascular, Inc. Stent Graft With Healing Promoting Necks
BRPI0807177B8 (pt) 2007-01-30 2021-06-22 Univ Pittsburgh dispositivo de enxerto de tecido tubular e método de preparação do mesmo
KR100932688B1 (ko) * 2007-07-06 2009-12-21 한국과학기술연구원 인공혈관용 이중막 구조의 튜브형 다공성 스캐폴드 및 그의제조방법
WO2009086458A1 (en) * 2007-12-27 2009-07-09 C.R. Bard. Inc. Vascular graft prosthesis having a reinforced margin for enhanced anastomosis
US8353814B2 (en) 2008-10-09 2013-01-15 Kips Bay Medical, Inc. Apparatus and method for mounting an external scaffold to a vascular graft

Also Published As

Publication number Publication date
US9237945B2 (en) 2016-01-19
CN114377204A (zh) 2022-04-22
EP2111185A2 (en) 2009-10-28
WO2008094971A2 (en) 2008-08-07
US20150150673A1 (en) 2015-06-04
CA2677033A1 (en) 2008-08-07
KR101719081B1 (ko) 2017-03-22
CN101663001A (zh) 2010-03-03
AU2008210523A1 (en) 2008-08-07
JP5950966B2 (ja) 2016-07-13
KR20090113318A (ko) 2009-10-29
WO2008094971A3 (en) 2008-10-16
US20080208323A1 (en) 2008-08-28
EP2111185A4 (en) 2012-11-14
BRPI0807177B1 (pt) 2020-06-30
JP5973121B2 (ja) 2016-08-23
AU2008210523B2 (en) 2013-08-22
US20160317280A1 (en) 2016-11-03
KR20150067388A (ko) 2015-06-17
US9333068B2 (en) 2016-05-10
JP2010516437A (ja) 2010-05-20
BRPI0807177A2 (pt) 2014-05-27
CN105343932A (zh) 2016-02-24
JP2014221394A (ja) 2014-11-27
EP2111185B1 (en) 2017-12-20
CA2677033C (en) 2015-04-28

Similar Documents

Publication Publication Date Title
EP2111185A4 (en) BIODEGRADABLE WRAPPING AND ITS USE
WO2011056705A3 (en) Bioerodible wraps and uses therefor
Huang et al. Engineering of arteries in vitro
ATE471977T1 (de) Vliesfaser für eine biomedizinische anwendung basierend auf poly(esteramid)en
MX2019007882A (es) Matriz y metodo de electrohilado.
WO2012122618A8 (pt) Composição imunogênica para modulação do sistema imune e seu uso, método de tratamento e prevenção de doenças, método para induzir a regeneração celular e método para recondução da resposta imune
ATE455566T1 (de) Verbundmaterial, insbesondere für die medizinische anwendung, und verfahren zu dessen herstellung
NZ603913A (en) Method of engrafting cells from solid tissues
UY31816A (es) Agente para el tratamiento y/o prevención de una enfemedad autoinmune y para la formación de células t reguladoras
GB2476624A (en) Compositions and methods for tissue repair with extracellular matrices
WO2014168719A8 (en) Use of microparticles and endothelial cells with decellularized organs and tissues
EP2181722A3 (en) Delayed gelation compositions and methods of use
BR112014003071A2 (pt) tratamento de doença vascular periférica com o uso de células derivadas do tecido do cordão umbilical
CN102631706B (zh) 低免疫原性猪真皮支架的制备方法
WO2008134305A3 (en) Tissue engineering devices and methods for luminal organs
Liu et al. Fabrication of a dual-layer cell-laden tubular scaffold for nerve regeneration and bile duct reconstruction
CN110585488A (zh) 一种新型复合材料制备的神经修复导管及其制备方法
Liberski et al. Knitting for heart valve tissue engineering
Goyal et al. Decellularization of caprine esophagus using fruit pericarp extract of Sapindus mukorossi
Li et al. Biomechanical properties of different segments of human umbilical cord vein and its value for clinical application
GB2456270A (en) Skin substitutes, preparation methods and uses thereof
Wu et al. Tween-80 improves single/coaxial electrospinning of three-layered bioartificial blood vessel
BR112018001581A2 (pt) não tecido de ilhas-no-mar enxertadas para alta capacidade de biosseparação de permuta de íons
Ghosh et al. Advancing biomedical applications: integrating textile innovations with tissue engineering
WO2014091796A1 (ja) 移植用細胞シートを運搬するためのキャリア

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B04C Request for examination: application reinstated [chapter 4.3 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/06/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REF. RPI 2582 DE 30/06/2020 QUANTO AO INVENTOR.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/01/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO