BRPI0809138A2 - ensaios utilizando partículas ativas-espectroscopia raman aumentada pela superfície (sers) - Google Patents

ensaios utilizando partículas ativas-espectroscopia raman aumentada pela superfície (sers)

Info

Publication number
BRPI0809138A2
BRPI0809138A2 BRPI0809138A BRPI0809138A BRPI0809138A2 BR PI0809138 A2 BRPI0809138 A2 BR PI0809138A2 BR PI0809138 A BRPI0809138 A BR PI0809138A BR PI0809138 A BRPI0809138 A BR PI0809138A BR PI0809138 A2 BRPI0809138 A2 BR PI0809138A2
Authority
BR
Brazil
Prior art keywords
sers
assays
raman spectroscopy
active particles
surface augmented
Prior art date
Application number
BRPI0809138A
Other languages
English (en)
Inventor
Adam Craig Curry
Alexander G Lastovich
Andrea Liebmann-Vinson
Christian Sandmann
Helen Hsieh
James L Schram
Kristin Weidemaier
Rajendra R Bhat
Robert E Pearson
Steven Keith
W Shannon Dillmore
W William Stewart
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Publication of BRPI0809138A2 publication Critical patent/BRPI0809138A2/pt
Publication of BRPI0809138B1 publication Critical patent/BRPI0809138B1/pt
Publication of BRPI0809138B8 publication Critical patent/BRPI0809138B8/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • G01N21/658Raman scattering enhancement Raman, e.g. surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BRPI0809138A 2007-03-20 2008-03-20 método para detectar a presença ou quantidade de um ou mais analitos em uma amostra biológica BRPI0809138B8 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US89580707P 2007-03-20 2007-03-20
US60/895.807 2007-03-20
US97601507P 2007-09-28 2007-09-28
US60/976.015 2007-09-28
US1374007P 2007-12-14 2007-12-14
US61/013.740 2007-12-14
PCT/US2008/057700 WO2008116093A2 (en) 2007-03-20 2008-03-20 Assays using surface-enhanced raman spectroscopy (sers)-active particles

Publications (3)

Publication Number Publication Date
BRPI0809138A2 true BRPI0809138A2 (pt) 2016-07-26
BRPI0809138B1 BRPI0809138B1 (pt) 2019-07-02
BRPI0809138B8 BRPI0809138B8 (pt) 2021-07-27

Family

ID=39766773

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809138A BRPI0809138B8 (pt) 2007-03-20 2008-03-20 método para detectar a presença ou quantidade de um ou mais analitos em uma amostra biológica

Country Status (10)

Country Link
US (2) US9823253B2 (pt)
EP (3) EP2126581B1 (pt)
JP (3) JP5451592B2 (pt)
CN (1) CN101680900B (pt)
AU (1) AU2008228813C1 (pt)
BR (1) BRPI0809138B8 (pt)
CA (2) CA2981992C (pt)
ES (2) ES2635272T3 (pt)
MX (1) MX2009009994A (pt)
WO (1) WO2008116093A2 (pt)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102565438B (zh) * 2005-04-01 2014-05-07 三菱化学美迪恩斯株式会社 反应杯
JP2010525333A (ja) * 2007-04-18 2010-07-22 ベクトン・ディキンソン・アンド・カンパニー Sersナノタグを用いる分析法
EP2152319B1 (en) 2007-06-06 2015-04-08 Becton Dickinson and Company Near-infrared dyes as surface enhanced raman scattering reporters
WO2009076323A2 (en) 2007-12-06 2009-06-18 Genalyte Inc. Monitoring enzymatic process
WO2009126336A1 (en) * 2008-04-11 2009-10-15 Becton, Dickinson And Company Methods of controlling the sensitivity and dynamic range of a homogeneous assay
JP5656853B2 (ja) 2008-10-27 2015-01-21 ジェナリーテ, インコーポレイテッド 光学的な探査及び検知に基づくバイオセンサ
JP2011033371A (ja) * 2009-07-30 2011-02-17 Beckman Coulter Inc 分析装置
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
JP2011158327A (ja) * 2010-01-29 2011-08-18 Beckman Coulter Inc 分析装置及び分析方法
JP2011163910A (ja) * 2010-02-09 2011-08-25 Beckman Coulter Inc 分注精度管理方法、分注量補正方法、攪拌性能管理方法、自動分析装置および分析キット
EP2542890B1 (en) 2010-03-01 2015-05-06 Quanterix Corporation Methods for extending dynamic range in assays for the detection of molecules or particles
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
RS55757B1 (sr) * 2010-03-22 2017-07-31 Sicpa Holding Sa Sers nanomarkeri selektivni prema talasnoj dužini
EP2577276A4 (en) * 2010-06-04 2017-01-25 Michael Himmelhaus Optical cavity mode excitations in magnetic fluorescent microparticles
EP3733866B1 (en) 2010-11-05 2023-11-15 Genalyte, Inc. Optical analyte detection systems and methods of use
CN102061164A (zh) * 2010-11-22 2011-05-18 东南大学 一种增强拉曼和荧光信号的纳米结构及其制备方法
KR101352342B1 (ko) * 2010-11-24 2014-02-17 서울대학교산학협력단 코어 물질과 쉘 물질 사이에 나노갭이 형성된 단일 나노입자 및 이의 제조방법
WO2012077756A1 (ja) * 2010-12-08 2012-06-14 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
CN102608093B (zh) * 2011-01-20 2014-04-30 中国科学院生态环境研究中心 一种多环芳烃检测方法
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
CA2731892A1 (fr) * 2011-02-18 2012-08-18 Universite De Montreal Sondes a diffusion raman a capsule nanometrique, methode de fabrication et utilisation
CN102183657B (zh) * 2011-02-24 2014-02-05 南京基蛋生物科技有限公司 一种依赖聚苯乙烯纳米粒大幅度增加化学发光磁酶免疫灵敏度的方法
DE112012001449T5 (de) * 2011-03-25 2014-01-30 Imra America, Inc. Vorrichtung und Verfahren zur oberflächenverstärkten Raman-Streuung
CN102206357B (zh) * 2011-03-28 2012-10-17 复旦大学 一种sers标签微球及其制备方法
JP5703098B2 (ja) * 2011-03-31 2015-04-15 富士フイルム株式会社 生体分子検出装置および生体分子検出方法
CN102525421A (zh) * 2011-05-18 2012-07-04 东南大学 一种具有增强拉曼和荧光信号的检测微针及其制备方法
CN103620358B (zh) * 2011-05-20 2016-07-06 惠普发展公司,有限责任合伙企业 表面增强拉曼光谱传感器、传感系统和方法
US9459257B2 (en) 2011-05-29 2016-10-04 Korea Research Institute Of Chemical Technology High-speed screening apparatus for a Raman analysis-based high-speed multiple drug
CN102323412B (zh) * 2011-08-09 2014-01-01 中国科学院合肥物质科学研究院 一种拉曼编码微球的用途及利用拉曼编码微球检测肿瘤标志物的方法
WO2013040782A1 (en) 2011-09-22 2013-03-28 East China University Of Science And Technology Metallic nanoparticles and methods for their preparation and use
JP5816291B2 (ja) * 2011-10-05 2015-11-18 株式会社日立ハイテクノロジーズ 生体分子分析方法及び生体分子分析装置
US9267889B1 (en) * 2011-10-12 2016-02-23 Stc.Unm High efficiency light absorbing and light emitting nanostructures
IN2014KN01168A (pt) 2011-11-02 2015-10-16 Univ Cape Town
EP2594942A1 (en) * 2011-11-16 2013-05-22 Koninklijke Philips Electronics N.V. Long rigid spacers to enhance binding kinetics in immunoassays
CN104105965B (zh) 2011-11-21 2016-07-06 爱贝斯股份有限公司 侧向流和相关免疫测定中的信号放大
EP2812676B1 (en) * 2012-02-07 2019-11-20 Materialytics LLC Methods and systems for analyzing samples
EP2825885B1 (en) * 2012-03-12 2021-05-12 The Board of Trustees of the University of Illinois Optical analyte detection systems with magnetic enhancement
US9733184B2 (en) * 2012-03-30 2017-08-15 Indian Institute Of Technology Madras Visual detection of mercury ions
ES2805025T3 (es) * 2012-04-12 2021-02-10 Becton Dickinson Co Métodos, sistemas y dispositivos para detectar e identificar microorganismos en muestras de cultivo microbiológicas
USD690826S1 (en) 2012-04-12 2013-10-01 Becton Dickinson And Company Vessel assembly
WO2013158504A1 (en) * 2012-04-17 2013-10-24 Ehrenkranz Joel R L Device for performing diagnostic test and methods for use thereof
US10132802B2 (en) 2012-04-17 2018-11-20 i-calQ, LLC Device for performing a diagnostic test and methods for use thereof
CN102721680B (zh) * 2012-06-18 2014-12-03 复旦大学 一种高灵敏检测t-DNA的SERS液相芯片方法
EP2880423B1 (en) 2012-07-29 2021-02-24 Hewlett-Packard Development Company, L.P. Scattering spectroscopy nanosensor
US9863884B2 (en) 2012-08-10 2018-01-09 Hamamatsu Photonics K.K. Surface-enhanced Raman scattering element, and method for producing same
CN104508466B (zh) 2012-08-10 2018-07-17 浜松光子学株式会社 表面增强拉曼散射元件
JP6151948B2 (ja) 2013-03-29 2017-06-21 浜松ホトニクス株式会社 表面増強ラマン散乱ユニット及びラマン分光分析方法
RU2537301C2 (ru) * 2012-09-10 2014-12-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Юго-Западный государственный университет" (ЮЗГУ) Сенсор для получения спектров гигантского комбинационного рассеяния и способ его изготовления
CN104823049A (zh) * 2012-10-01 2015-08-05 普林斯顿大学理事会 具有增强的光学信号的微流体传感器
CN105102979B (zh) * 2013-01-29 2017-05-03 生物辐射海法有限公司 利用磁性纳米粒子的检测测定法
WO2014143637A1 (en) 2013-03-15 2014-09-18 The Board Of Trustees Of The University Of Illinois Methods and compositions for enhancing immunoassays
WO2014144133A1 (en) * 2013-03-15 2014-09-18 The Trustees Of The Princeton University Analyte detection enhancement by targeted immobilization, surface amplification, and pixelated reading and analysis
JP6245664B2 (ja) * 2013-08-23 2017-12-13 株式会社右近工舎 表面増強ラマン散乱分光測定用基板及びそれを用いた装置
WO2015123005A1 (en) * 2014-02-14 2015-08-20 Becton, Dickinson And Company Sers nanoparticles and methods for using the same
JP6440166B2 (ja) * 2014-03-28 2018-12-19 大日本塗料株式会社 イムノクロマトキット
AU2015256932B2 (en) 2014-05-08 2019-11-07 Mytech Co., Ltd. Plasmonic chip, and cancer disease diagnosis methods respectively employing fluorescent image and raman spectroscopy and each using same
WO2015175398A1 (en) 2014-05-12 2015-11-19 President And Fellows Of Harvard College Systems and methods for making and using sensors, probes, and other devices
CN104062276A (zh) * 2014-06-06 2014-09-24 上海交通大学 基于dna快速组装技术的核壳拉曼探针的制备方法
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
GB201418483D0 (en) * 2014-10-17 2014-12-03 Johnson Matthey Plc Analytical method and composition
WO2016111538A2 (ko) * 2015-01-09 2016-07-14 한양대학교 에리카산학협력단 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법
EP3259286A4 (en) * 2015-02-19 2018-07-11 Ionica Sciences Reagents and methods for detecting infectious diseases
US10935545B2 (en) * 2015-05-13 2021-03-02 Slsbio Co., Ltd. Simultaneous analysis method for multiple targets using multiple metal nano-tags
WO2016187588A1 (en) * 2015-05-21 2016-11-24 Lamdagen Corporation Plasmonic nanoparticles and lspr-based assays
PT3331818T (pt) * 2015-08-04 2024-08-30 Zoetis Services Llc Amplificação de sinal em ensaios de parceiro de ligação específica plasmónicos à base de solução
CN105181670B (zh) * 2015-08-26 2017-10-10 福建师范大学 一种利用细胞分泌蛋白sers光谱检测药物细胞毒性方法
JP6507969B2 (ja) * 2015-09-25 2019-05-08 コニカミノルタ株式会社 ガス検知方法及びガス検知装置
KR102396249B1 (ko) 2015-10-14 2022-05-09 삼성전자주식회사 라만 스펙트럼을 이용한 사용자 인증 장치 및 방법
WO2017091640A1 (en) * 2015-11-24 2017-06-01 The Johns Hopkins University Raman spectroscopy reporters and methods for molecular imaging of tissue in vivo
KR101802386B1 (ko) 2015-12-11 2017-11-30 재단법인 대구경북첨단의료산업진흥재단 표면증강라만산란(sers) 나노입자, 이의 제조 방법 및 이의 응용
CN105372226B (zh) * 2015-12-17 2019-01-11 华南师范大学 一种水体中氯霉素cap的定量检测方法
JP6683907B2 (ja) * 2016-01-08 2020-04-22 積水メディカル株式会社 免疫凝集用粒子及びその製造方法
WO2017127759A1 (en) * 2016-01-22 2017-07-27 The Regents Of The University Of California Formation and use of embedded solutions in nanoscale materials
TW201804149A (zh) * 2016-06-21 2018-02-01 日產化學工業有限公司 藉由拉曼散射之簡易感測法
WO2018052464A1 (en) * 2016-09-16 2018-03-22 Plexbio Co., Ltd. Methods and systems for multiplex assays
WO2018102631A1 (en) * 2016-12-01 2018-06-07 University Of Florida Research Foundation, Inc. Polymer conjugates, methods of making polymer conjugates, and methods of using polymer conjugates
CN106623894B (zh) * 2016-12-02 2018-11-13 中国人民解放军国防科学技术大学 磁性复合颗粒及其制备方法和应用
KR102486615B1 (ko) * 2017-01-30 2023-01-11 조에티스 서비시즈 엘엘씨 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체
US11366065B2 (en) 2017-02-03 2022-06-21 Samsung Life Public Welfare Foundation Point-of-care system and method for diagnosing acute febrile illness
WO2018143684A1 (ko) * 2017-02-03 2018-08-09 사회복지법인 삼성생명공익재단 급성 열성 질환을 진단하기 위한 현장 진단 시스템 및 방법
GB201704128D0 (en) * 2017-03-15 2017-04-26 Univ Swansea Method and apparatus for use in diagnosis and monitoring of colorectal cancer
CA3065360A1 (en) * 2017-05-30 2018-12-06 Ellume Limited Nanoparticle aggregates
US10156658B1 (en) 2017-06-06 2018-12-18 Saudi Arabian Oil Company Detecting a tracer in a hydrocarbon reservoir
WO2019004804A2 (ko) * 2017-06-30 2019-01-03 한국화학연구원 패혈증 진단용 키트 및 이를 이용한 진단방법
CN109307669A (zh) * 2017-07-28 2019-02-05 上海海洋大学 基于末端转移酶扩增核酸链制备核壳sers结构的方法
CN107817340A (zh) * 2017-08-01 2018-03-20 东南大学 一种sers技术检测多药耐药蛋白的试剂盒及其应用
EP4427841A3 (en) * 2017-09-08 2024-11-13 President And Fellows Of Harvard College Nanosensor methods and apparatuses for determination of analytes
CN108872185B (zh) * 2018-03-22 2021-07-27 苏州英菲尼纳米科技有限公司 一种sers芯片的制备方法
CN108872157B (zh) * 2018-04-20 2019-11-12 华中科技大学 一种侧面抛光开环型pcf-spr传感器
RU2677703C1 (ru) * 2018-04-23 2019-01-21 Федеральное государственное унитарное предприятие "ВСЕРОССИЙСКИЙ НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИТУТ ОПТИКО-ФИЗИЧЕСКИХ ИЗМЕРЕНИЙ" (ФГУП "ВНИИОФИ") Способ измерения концентрации аналита в плазме крови
KR102582064B1 (ko) * 2018-07-11 2023-09-25 한국과학기술연구원 근적외선 흡수 염료 함유 나노입자, 이의 제조방법, 및 이의 용도
CN112218877B (zh) 2018-08-27 2025-07-25 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
CN109187484B (zh) * 2018-09-13 2020-12-04 广西师范大学 一种用亲和反应调控碳点催化sers检测生物素的方法
WO2020066654A1 (ja) * 2018-09-28 2020-04-02 富士フイルム株式会社 免疫クロマトグラフィー用複合粒子及びその製造方法、並びに、免疫クロマトグラフィー
CN109387500B (zh) * 2018-09-29 2021-01-12 南京农业大学 一种基于磁氧化石墨烯复合金星@金-银合金纳米颗粒对大肠杆菌进行检测的方法
CN113646633A (zh) * 2018-10-17 2021-11-12 易兹代亚科技股份有限公司 生物材料侦测微颗粒和使用其的生物材料侦测方法
US10739269B2 (en) * 2018-10-18 2020-08-11 Baker Hughes, A Ge Company, Llc Detection of trace chemicals in oil and gas applications
WO2020094554A1 (en) * 2018-11-05 2020-05-14 Protatouans - Etaireia Viotechnologias Monoprosopi Etaireia Periorismenis Eythinis Method for the detection of analytes in antibody-based assays via a sequential microparticle suspension system
CN113826011A (zh) 2019-02-27 2021-12-21 纳米马赛克公司 纳米传感器及其用途
WO2020190746A1 (en) 2019-03-15 2020-09-24 Saudi Arabian Oil Company Bulk synthesis of janus nanomaterials
IL285912B2 (en) * 2019-05-13 2024-06-01 Unisers Ltd A method for determining a characteristic of particles in a liquid sample and/or for determining a contamination characteristic of the liquid sample
CN110455714B (zh) * 2019-07-11 2021-09-17 吉林师范大学 一种能自然消除荧光背景的sers基底及其制备方法
US12228512B2 (en) 2019-07-16 2025-02-18 Saudi Arabian Oil Company Multipurpose microfluidics devices for rapid on-site optical chemical analysis
CN110441284B (zh) * 2019-07-23 2022-02-15 海南大学 一种可用于痕量检测的表面增强拉曼散射芯片的制备方法及所得产品和应用
KR102257511B1 (ko) * 2019-08-13 2021-05-31 고려대학교 산학협력단 자성-광학 복합 나노구조체
AU2020332709B9 (en) * 2019-08-22 2025-10-30 Cape Breton University Methods of modifying a liquid sample containing an analyte so as to increase sers signal intensity of the analyte, as well as a probe for remote sensing of an analyte using sers
CN114599958A (zh) * 2019-10-28 2022-06-07 君诺贝生物技术公司 通过粒子复合物的离散计数进行分析物检测和量化
EP4667103A3 (en) * 2019-12-04 2026-01-21 Becton, Dickinson and Company Magnetic capture bead mediated molecular barcoding of nucleic acid targets in single particles and compositions for use in the same
WO2021193589A1 (ja) * 2020-03-23 2021-09-30 積水化学工業株式会社 検査方法、検査キット及び検査システム
CN111551534A (zh) * 2020-05-18 2020-08-18 上海交通大学 基于表面增强拉曼探针的试剂盒及其应用、成像方法
US11422285B2 (en) 2020-06-17 2022-08-23 Saudi Arabian Oil Company Nanofluidic chips as micromodels for carbonate reservoirs
US11773715B2 (en) 2020-09-03 2023-10-03 Saudi Arabian Oil Company Injecting multiple tracer tag fluids into a wellbore
CN113552197A (zh) * 2020-11-10 2021-10-26 淄博新维陶瓷科技有限公司 核壳二氧化钛纳米颗粒修饰dna传感器的构建方法及应用
US11660595B2 (en) 2021-01-04 2023-05-30 Saudi Arabian Oil Company Microfluidic chip with multiple porosity regions for reservoir modeling
JP7591260B2 (ja) * 2021-01-07 2024-11-28 国立大学法人静岡大学 表面増強ラマン散乱による高感度の標的物質の検出のためのナノゲル若しくはキット及び検出方法
US12019038B2 (en) 2021-01-21 2024-06-25 Saudi Arabian Oil Company Evaluation of source rock samples from subterranean reservoirs
US11534759B2 (en) 2021-01-22 2022-12-27 Saudi Arabian Oil Company Microfluidic chip with mixed porosities for reservoir modeling
CN112986213B (zh) * 2021-03-12 2022-03-22 福州大学 一种检测口腔癌dna的拉曼光谱传感器
CN112881363A (zh) * 2021-03-25 2021-06-01 浙江理工大学 一种磁基贵金属纳米复合颗粒组装阵列型sers基底的方法
EP4334704A4 (en) * 2021-05-03 2025-07-02 Univ Bar Ilan OPTICAL EMISSION BIODETECTION USING SHORT AGGREGATION TIME MAGNETIC BEADS
RU2765617C1 (ru) * 2021-05-25 2022-02-01 федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский ядерный университет "МИФИ" (НИЯУ МИФИ) Способ регистрации спектров гигантского комбинационного рассеяния света и проточная ячейка для его реализации
WO2022271238A1 (en) * 2021-06-21 2022-12-29 Ohio State Innovation Foundation Detection of a target virus via surface enhanced raman spectroscopy (sers) using a peptide-modified nanostructured metal
KR102594680B1 (ko) * 2021-10-08 2023-10-25 한국생명공학연구원 표면증강라만산란 기반 표적 바이러스 면역검정법
US11796517B2 (en) 2021-11-09 2023-10-24 Saudi Arabian Oil Company Multifunctional magnetic tags for mud logging
US12140582B2 (en) 2021-11-09 2024-11-12 Saudi Arabian Oil Company Multifunctional polysaccharide-based mud logging barcode tracers
US12110448B2 (en) 2021-11-09 2024-10-08 Saudi Arabian Oil Company Multifunctional fluorescent tags for subterranean applications
US12253467B2 (en) 2021-12-13 2025-03-18 Saudi Arabian Oil Company Determining partition coefficients of tracer analytes
US11885790B2 (en) 2021-12-13 2024-01-30 Saudi Arabian Oil Company Source productivity assay integrating pyrolysis data and X-ray diffraction data
US11999855B2 (en) 2021-12-13 2024-06-04 Saudi Arabian Oil Company Fluorescent dye molecules having hydrophilicity and hydrophobicity for tracer applications
US11725139B2 (en) 2021-12-13 2023-08-15 Saudi Arabian Oil Company Manipulating hydrophilicity of conventional dye molecules for water tracer applications
US12440821B2 (en) 2021-12-13 2025-10-14 Saudi Arabian Oil Company Method for tracing subterranean formations with oil-soluble organic molecular tracers and extracting them of from oil phases
US12000278B2 (en) 2021-12-16 2024-06-04 Saudi Arabian Oil Company Determining oil and water production rates in multiple production zones from a single production well
WO2023215396A1 (en) * 2022-05-03 2023-11-09 Amplified Sciences, Inc. Devices, systems, and methods for classification of pancreatic cells
US12188350B2 (en) 2022-06-08 2025-01-07 Saudi Arabian Oil Company Fluorescent dye oil tracer compositions
CN114994016A (zh) * 2022-06-09 2022-09-02 浙江省肿瘤医院 一种纯半导体复合纳米材料、其制备方法和检测癌细胞的方法
GB202214119D0 (en) * 2022-09-27 2022-11-09 Univ Strathclyde Nanosensor
CN116429746B (zh) * 2022-12-13 2026-01-06 中国科学院宁波材料技术与工程研究所 一种多功能性复合生物探针及其制备方法和应用
US12385858B2 (en) 2023-03-10 2025-08-12 Saudi Arabian Oil Company Evaluating source rock based on time series analysis
US20250035554A1 (en) * 2023-07-26 2025-01-30 Thermo Scientific Portable Analytical Instruments Inc. System and method for spectroscopic determination of a chemometric model from sample scans

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266498A (en) 1989-10-27 1993-11-30 Abbott Laboratories Ligand binding assay for an analyte using surface-enhanced scattering (SERS) signal
US5472881A (en) 1992-11-12 1995-12-05 University Of Utah Research Foundation Thiol labeling of DNA for attachment to gold surfaces
NZ292756A (en) * 1994-08-31 1998-10-28 Activated Cell Therapy Inc Cell separation apparatus and method using centrifugation and density mediums
GB9517955D0 (en) * 1995-07-25 1995-11-08 Univ Strathclyde Nucleotide sequence detection and analysis
JP2614997B2 (ja) * 1996-01-29 1997-05-28 オリンパス光学工業株式会社 凝集反応のための反応促進装置
US5945281A (en) 1996-02-02 1999-08-31 Becton, Dickinson And Company Method and apparatus for determining an analyte from a sample fluid
US7169556B2 (en) 1996-07-29 2007-01-30 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US6180415B1 (en) 1997-02-20 2001-01-30 The Regents Of The University Of California Plasmon resonant particles, methods and apparatus
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US5906744A (en) 1997-04-30 1999-05-25 Becton Dickinson And Company Tube for preparing a plasma specimen for diagnostic assays and method of making thereof
US5860937A (en) 1997-04-30 1999-01-19 Becton, Dickinson & Company Evacuated sample collection tube with aqueous additive
AUPP004497A0 (en) 1997-10-28 1997-11-20 University Of Melbourne, The Stabilized particles
JP3737257B2 (ja) * 1997-11-17 2006-01-18 倉敷紡績株式会社 2次元表現によるスペクトルデータの処理方法及び補正方法
US6699724B1 (en) 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
OA12310A (en) * 1998-04-16 2006-05-12 Kojima Haruo Method for separating magnetic particles mixed in fluid, separating system and separator.
US6534280B1 (en) * 1999-04-15 2003-03-18 Padmanabhan P. Nair Noninvasive detection of colorectal cancer and other gastrointestinal pathology
US20010055764A1 (en) * 1999-05-07 2001-12-27 Empedocles Stephen A. Microarray methods utilizing semiconductor nanocrystals
US8497131B2 (en) 1999-10-06 2013-07-30 Becton, Dickinson And Company Surface enhanced spectroscopy-active composite nanoparticles comprising Raman-active reporter molecules
EP1804053A1 (en) 1999-10-06 2007-07-04 Oxonica Inc. Surface-enhanced spectroscopy-active composite nanoparticles
US7192778B2 (en) 1999-10-06 2007-03-20 Natan Michael J Surface enhanced spectroscopy-active composite nanoparticles
US6514415B2 (en) 2000-01-31 2003-02-04 Dexter Magnetic Technologies, Inc. Method and apparatus for magnetic separation of particles
JP2001272395A (ja) * 2000-03-24 2001-10-05 Asahi Kasei Corp 血液中のヒスタミン分離方法および測定方法並びに測定用組成物
EP2085781B2 (en) * 2000-10-06 2020-03-11 Life Technologies Corporation Transfectable micelles containing semiconductor nanocrystals
ATE384954T1 (de) 2000-11-08 2008-02-15 Becton Dickinson Co Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe
US6861263B2 (en) 2001-01-26 2005-03-01 Surromed, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
CA2451795A1 (en) * 2001-06-26 2003-01-09 Paul M. Mathews Cell-based high-throughput screening methods
US6913825B2 (en) 2001-09-20 2005-07-05 University Of Notre Dame Du Lac Process for making mesoporous silicate nanoparticle coatings and hollow mesoporous silica nano-shells
US20030211488A1 (en) 2002-05-07 2003-11-13 Northwestern University Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection
GB0216197D0 (en) * 2002-07-12 2002-08-21 Univ Strathclyde Serrs active particles
US20040038318A1 (en) * 2002-08-23 2004-02-26 Bell Michael L. Creatine kinase isoenzyme determination in multiplexed assays
WO2004070056A2 (en) * 2003-02-07 2004-08-19 Diagnocure Inc. Method to detect prostate cancer in a sample
US7588827B2 (en) * 2003-08-18 2009-09-15 Emory University Surface enhanced Raman spectroscopy (SERS)-active composite nanoparticles, methods of fabrication thereof, and methods of use thereof
JP4381752B2 (ja) * 2003-09-02 2009-12-09 シスメックス株式会社 光学的定量方法及び光学的定量装置
US20050074779A1 (en) * 2003-10-02 2005-04-07 Tuan Vo-Dinh SERS molecular probe for diagnostics and therapy
WO2005062982A2 (en) * 2003-12-23 2005-07-14 Xing-Xiang Li Signal amplification methods for analyte detection
US20050191665A1 (en) * 2003-12-29 2005-09-01 Xing Su Composite organic-inorganic nanoclusters
US20050148098A1 (en) * 2003-12-30 2005-07-07 Xing Su Methods for using raman spectroscopy to obtain a protein profile of a biological sample
WO2005075997A1 (ja) * 2004-02-03 2005-08-18 Asahi Kasei Kabushiki Kaisha 磁気ビーズを用いた被検物質の検出方法
JP2005241550A (ja) * 2004-02-27 2005-09-08 Hitachi Ltd 糞便回収容器
EP3656735A1 (en) 2004-04-23 2020-05-27 Becton, Dickinson and Company Surface enhanced spectroscopy-active composite nanoparticles
US7403281B2 (en) 2004-05-07 2008-07-22 University Of Wyoming Raman spectrometer
US7002679B2 (en) 2004-05-11 2006-02-21 Duke University Encoded excitation source Raman spectroscopy methods and systems
EP1621890A1 (en) * 2004-07-26 2006-02-01 bioMerieux B.V. Device and method for separating, mixing and concentrating magnetic particles with a fluid and use thereof in purification methods
US9494581B2 (en) * 2004-08-24 2016-11-15 University Of Wyoming System and method for Raman spectroscopy assay using paramagnetic particles
US7776547B2 (en) 2004-08-26 2010-08-17 Intel Corporation Cellular analysis using Raman surface scanning
WO2006060734A2 (en) * 2004-12-03 2006-06-08 Trustees Of Boston University Nanostructured substrate for for surface enhanced raman scattering
US20060216835A1 (en) * 2005-03-24 2006-09-28 General Electric Company Method of separating unattached Raman-active tag from bioassay or other reaction mixture
DE602006010956D1 (de) * 2005-11-01 2010-01-21 Jsr Corp Magnetische Partikel für die Diagnostik
JP4687891B2 (ja) * 2005-11-01 2011-05-25 Jsr株式会社 診断薬用磁性粒子
US8003408B2 (en) * 2005-12-29 2011-08-23 Intel Corporation Modification of metal nanoparticles for improved analyte detection by surface enhanced Raman spectroscopy (SERS)
ES2493990T3 (es) * 2006-02-08 2014-09-12 Becton Dickinson And Company Ensayos con nanoetiquetas SERS

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