BRPI0809667A2 - COMPOUND, MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING AND USE OF THE COMPOUND - Google Patents

COMPOUND, MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING AND USE OF THE COMPOUND

Info

Publication number
BRPI0809667A2
BRPI0809667A2 BRPI0809667-8A2A BRPI0809667A BRPI0809667A2 BR PI0809667 A2 BRPI0809667 A2 BR PI0809667A2 BR PI0809667 A BRPI0809667 A BR PI0809667A BR PI0809667 A2 BRPI0809667 A2 BR PI0809667A2
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
composition containing
medicinal product
medicinal
Prior art date
Application number
BRPI0809667-8A2A
Other languages
Portuguese (pt)
Inventor
Markus Gude
Christian Hubschwerlen
Jean-Philippe Surivet
Cornelia Zumbrunn-Acklin
Georg Rueedi
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0809667A2 publication Critical patent/BRPI0809667A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0809667-8A2A 2007-04-11 2008-04-10 COMPOUND, MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING AND USE OF THE COMPOUND BRPI0809667A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2007051292 2007-04-11
IB2008050746 2008-02-29
PCT/IB2008/051356 WO2008126024A2 (en) 2007-04-11 2008-04-10 Oxazolidinone antibiotic derivatives

Publications (1)

Publication Number Publication Date
BRPI0809667A2 true BRPI0809667A2 (en) 2014-10-07

Family

ID=39722506

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809667-8A2A BRPI0809667A2 (en) 2007-04-11 2008-04-10 COMPOUND, MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING AND USE OF THE COMPOUND

Country Status (16)

Country Link
US (1) US8114867B2 (en)
EP (1) EP2146987B1 (en)
JP (1) JP5363457B2 (en)
KR (1) KR101563752B1 (en)
CN (1) CN101657450B (en)
AR (1) AR066012A1 (en)
AU (1) AU2008238894B2 (en)
BR (1) BRPI0809667A2 (en)
CA (1) CA2679069C (en)
CL (1) CL2008001003A1 (en)
ES (1) ES2560870T3 (en)
MX (1) MX2009010641A (en)
PL (1) PL2146987T3 (en)
RU (1) RU2506263C2 (en)
TW (1) TWI415614B (en)
WO (1) WO2008126024A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5323088B2 (en) 2007-12-18 2013-10-23 アクテリオン ファーマシューティカルズ リミテッド 5-Aminocyclylmethyl-oxazolidin-2-one derivatives
BRPI0907892A2 (en) 2008-02-20 2015-07-28 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compound, medicine, pharmaceutical composition containing and use thereof
CA2713187C (en) 2008-02-22 2016-06-07 Actelion Pharmaceuticals Ltd Oxazolidinone derivatives
WO2010015985A1 (en) * 2008-08-04 2010-02-11 Actelion Pharmaceuticals Ltd Tricyclic alkylaminomethyloxazolidinone derivatives
JP4833385B1 (en) 2008-10-07 2011-12-07 アクテリオン ファーマシューティカルズ リミテッド Tricyclic oxazolidinone antibiotic compounds
ES2395491T3 (en) * 2008-10-10 2013-02-13 Actelion Pharmaceuticals Ltd. 2-Benzothiophenyl and 2-naphthyl-oxazolidinones and their azaisósteros analogs as antibacterial agents
CN102232078B (en) 2008-12-12 2014-07-16 埃科特莱茵药品有限公司 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
EP2509997B1 (en) * 2009-12-07 2017-08-30 i2 Pharmaceuticals, Inc. Conjugates comprising an antibody surrogate scaffold with improved pharmacokinetic properties
EP2377850A1 (en) * 2010-03-30 2011-10-19 Pharmeste S.r.l. TRPV1 vanilloid receptor antagonists with a bicyclic portion
TW201309689A (en) 2011-02-07 2013-03-01 Daiichi Sankyo Co Ltd Amino group-containing pyrrolidinone derivatives
WO2013021363A1 (en) 2011-08-11 2013-02-14 Actelion Pharmaceuticals Ltd Quinazoline-2,4-dione derivatives
IN2014CN04126A (en) * 2011-11-08 2015-07-10 Actelion Pharmaceuticals Ltd
TW201326180A (en) 2011-11-30 2013-07-01 Actelion Pharmaceuticals Ltd 3,7-disubstituted octahydro-2H-pyrido[4,3-e][1,3]oxazin-2-one antibiotics
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
ES2594553T3 (en) * 2012-08-17 2016-12-21 Basf Se Procedure for manufacturing benzoxazinones
MA38588B1 (en) * 2013-04-16 2018-04-30 Idorsia Pharmaceuticals Ltd Bi-aromatic antibacterial derivatives
AR102256A1 (en) * 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH REPLACEMENT OF AMINOALCOXI
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
CA3012569A1 (en) * 2016-02-08 2017-08-17 Redx Pharma Plc Antibacterial compounds
EP3413976A1 (en) * 2016-02-08 2018-12-19 Redx Pharma PLC Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds
GB2550437B (en) * 2016-05-20 2021-06-23 Bugworks Res Inc Heterocyclic compounds useful as anti-bacterial agents and method for production
TW201833120A (en) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 Aryloxazolidinone antibiotic compound
US10912780B2 (en) 2017-06-08 2021-02-09 Bugworks Research, Inc. Heterocyclic compounds useful as anti-bacterial agents and method for production thereof
CN111527093B (en) * 2017-11-29 2023-06-09 巴格沃克斯研究有限公司 Antibacterial Heterocyclic Compounds and Their Synthesis
JP7473204B2 (en) * 2018-03-28 2024-04-23 バグワークス・リサーチ・インコーポレイテッド Oxazolidinone antibiotic compounds and methods of preparation
CN117532894B (en) * 2023-12-05 2024-06-14 东莞美泰电子有限公司 PU leather hot-pressing leather pasting technology for protecting parts

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU698867B2 (en) 1995-04-21 1998-11-12 Shinnippon Pharmaceutical Inc. Fused imidazo 1,2-a pyridines
DE69616366T2 (en) * 1995-09-01 2002-07-04 Upjohn Co PHENYLOXAZOLIDINONE WITH A C-C BOND TO 4-8 UNIT HETEROCYCLES
CA2331735A1 (en) 1998-05-08 1999-11-18 Smithkline Beecham P.L.C. Phenylurea and phenylthio urea derivatives
WO2000040554A1 (en) 1999-01-07 2000-07-13 American Home Products Corporation Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
JP2003503403A (en) 1999-06-28 2003-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Respiratory syncytial virus replication inhibitor
CN1452619A (en) 2000-07-26 2003-10-29 史密斯克莱·比奇曼公司 Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
AU2003224345A1 (en) * 2002-04-30 2003-11-17 Orchid Chemicals & Pharmaceuticals Antibacterial agents
AR040336A1 (en) 2002-06-26 2005-03-30 Glaxo Group Ltd PIPERIDINE COMPOUND, USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND PROCEDURE TO PREPARE SUCH COMPOUND
AR040335A1 (en) 2002-06-26 2005-03-30 Glaxo Group Ltd CYCLLOHEXAN OR CYCLHEXENE COMPOUND, USE OF THE SAME TO PREPARE A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, PROCEDURE AND INTERMEDIATE COMPOUNDS OF UTILITY TO PREPARE SUCH COMPOUND
JP4602903B2 (en) * 2002-10-10 2010-12-22 モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー New compounds with antibacterial activity
DE60324179D1 (en) 2002-12-04 2008-11-27 Glaxo Group Ltd CHINOLINE AND NITROGENIC DERIVATEDAVAN AND THEIR USE AS ANTIBACTERIAL AGENTS
AR042486A1 (en) 2002-12-18 2005-06-22 Glaxo Group Ltd QUINOLINE AND NAFTIRIDINE COMPOSITE HALOSUSTITUDED IN POSITION 3, PROCEDURE TO PREPARE THE COMPOUND, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE SUCH COMPOSITION.
DE10316081A1 (en) 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie New compounds with antibacterial activity
EP1484304A1 (en) 2003-05-28 2004-12-08 Dainippon Ink And Chemicals, Inc. Process for the preparation of fluorophenylalkylene acid derivatives
EP1796466A4 (en) 2004-06-15 2009-09-02 Glaxo Group Ltd Antibacterial agents
FR2872164B1 (en) * 2004-06-29 2006-11-17 Aventis Pharma Sa QUINOLINE-4-SUBSTITUTED DERIVATIVES, PROCESS AND PREPARATION INTERMEDIATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
BRPI0514381A (en) * 2004-07-30 2008-06-10 Palumed Sa hybrid aminoquinoline-antibiotic compounds, pharmaceutical compositions, method of preparation and use thereof
DE102004041163A1 (en) 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie New compounds with antibacterial activity
JP4887297B2 (en) 2004-09-24 2012-02-29 アクテリオン ファーマシューティカルズ リミテッド New bicyclic antibiotics
JP5314244B2 (en) 2004-10-27 2013-10-16 富山化学工業株式会社 Novel nitrogen-containing heterocyclic compounds and salts thereof
GB0426373D0 (en) 2004-12-01 2005-01-05 Syngenta Ltd Fungicides
DE602006016564D1 (en) 2005-03-03 2010-10-14 Santen Pharmaceutical Co Ltd NEW CYCLIC COMPOUND WITH CHINOLYL ALKYLTHIOGROUP
AU2006230364B2 (en) 2005-03-31 2012-09-13 Janssen Pharmaceutica N.V. Bicyclic pyrazole compounds as antibacterial agents
WO2007016610A2 (en) 2005-08-02 2007-02-08 Glaxo Group Limited Antibacterial agents
WO2007069555A1 (en) 2005-12-12 2007-06-21 Meiji Seika Kaisha, Ltd. Novel 16-membered cyclic 4”-0-carbamoyl azalide derivative and process for producing same
JP2009524643A (en) 2006-01-26 2009-07-02 アクテリオン ファーマシューティカルズ リミテッド Tetrahydropyran antibiotics

Also Published As

Publication number Publication date
US8114867B2 (en) 2012-02-14
US20100137290A1 (en) 2010-06-03
TWI415614B (en) 2013-11-21
TW200843780A (en) 2008-11-16
CA2679069A1 (en) 2008-10-23
JP5363457B2 (en) 2013-12-11
CA2679069C (en) 2016-06-07
RU2506263C2 (en) 2014-02-10
WO2008126024A2 (en) 2008-10-23
MX2009010641A (en) 2009-10-23
KR101563752B1 (en) 2015-10-27
KR20090130112A (en) 2009-12-17
JP2010523645A (en) 2010-07-15
AU2008238894A1 (en) 2008-10-23
ES2560870T3 (en) 2016-02-23
RU2009141310A (en) 2011-05-20
EP2146987B1 (en) 2015-12-02
PL2146987T3 (en) 2016-05-31
WO2008126024A3 (en) 2008-12-04
EP2146987A2 (en) 2010-01-27
AR066012A1 (en) 2009-07-15
CN101657450B (en) 2014-04-23
CN101657450A (en) 2010-02-24
CL2008001003A1 (en) 2008-10-17
AU2008238894B2 (en) 2013-06-20

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: IDORSIA PHARMACEUTICALS LTD (CH)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B25C Requirement related to requested transfer of rights

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2513 DE 06-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B25B Requested transfer of rights rejected

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

Free format text: INDEFERIDO O PEDIDO DE TRANSFERENCIA CONTIDO NA PETICAO 870170095261 DE 07/12/2017, DEVIDO AO DESPACHO PUBLICADO NA RPI 2529 DE 25/06/2019.