BRPI0811092A2 - Método de determinação do grau de um tumor, e, uso de 1 3c-piruvato hiperpolarizado - Google Patents

Método de determinação do grau de um tumor, e, uso de 1 3c-piruvato hiperpolarizado

Info

Publication number
BRPI0811092A2
BRPI0811092A2 BRPI0811092-1A2A BRPI0811092A BRPI0811092A2 BR PI0811092 A2 BRPI0811092 A2 BR PI0811092A2 BR PI0811092 A BRPI0811092 A BR PI0811092A BR PI0811092 A2 BRPI0811092 A2 BR PI0811092A2
Authority
BR
Brazil
Prior art keywords
determining
tumor degree
tumor
degree
Prior art date
Application number
BRPI0811092-1A2A
Other languages
English (en)
Inventor
Ralf Eugene Hurd
John Kurhanewicz
Daniel Blackburn Vigneron
Sarah Jane Nelson
Original Assignee
Gen Electric
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Electric, Univ California filed Critical Gen Electric
Publication of BRPI0811092A2 publication Critical patent/BRPI0811092A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4375—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the male reproductive system
    • A61B5/4381—Prostate evaluation or disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/485—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Signal Processing (AREA)
  • Gynecology & Obstetrics (AREA)
  • Optics & Photonics (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
BRPI0811092-1A2A 2007-05-17 2008-05-16 Método de determinação do grau de um tumor, e, uso de 1 3c-piruvato hiperpolarizado BRPI0811092A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93846807P 2007-05-17 2007-05-17
PCT/NO2008/000171 WO2008143519A1 (en) 2007-05-17 2008-05-16 Mr methods of grading a tumor using an imaging medium that comprises hyperpolarised 13c-pyruvate

Publications (1)

Publication Number Publication Date
BRPI0811092A2 true BRPI0811092A2 (pt) 2014-12-09

Family

ID=39722634

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811092-1A2A BRPI0811092A2 (pt) 2007-05-17 2008-05-16 Método de determinação do grau de um tumor, e, uso de 1 3c-piruvato hiperpolarizado

Country Status (11)

Country Link
US (1) US20110020235A1 (pt)
EP (1) EP2144561B1 (pt)
JP (1) JP2010529868A (pt)
KR (2) KR20100023802A (pt)
CN (2) CN101730504A (pt)
AU (1) AU2008253822B2 (pt)
BR (1) BRPI0811092A2 (pt)
CA (1) CA2683023C (pt)
MX (1) MX2009011855A (pt)
RU (1) RU2494672C2 (pt)
WO (1) WO2008143519A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120035464A1 (en) * 2009-04-20 2012-02-09 Koninklijke Philips Electronics N.V. Control apparatus for controlling a therapeutic apparatus
DE102011082181B3 (de) * 2011-09-06 2013-02-21 Siemens Ag Korrektur eines Bestrahlungsplans auf Grundlage von Magnetresonanzdaten
EP2950826B1 (en) 2013-01-31 2019-09-18 Bracco Imaging S.p.A Hyperpolarized esters as metabolic markers in mri
KR101516634B1 (ko) * 2014-07-09 2015-05-06 연세대학교 산학협력단 13c-자기공명분광영상을 이용한 암 환자의 치료 예후를 예측하는 방법
US10667718B2 (en) * 2015-03-26 2020-06-02 Case Western Reserve University Quantitative prostate cancer imaging with magnetic resonance fingerprinting (MRF)
CN109477872A (zh) * 2016-03-10 2019-03-15 纪念斯隆凯特琳癌症中心 超极化微核磁共振系统和方法
DE102016218715A1 (de) * 2016-09-28 2018-03-29 Siemens Healthcare Gmbh Verbesserte Erzeugung kombinierter Magnetresonanzbilder
KR101939454B1 (ko) * 2017-03-21 2019-01-16 전남대학교산학협력단 생체 내 과분극화 c13 피루베이트 자기공명분광법을 이용하여 새로운 정량적 생체지표를 통한 비알코올성 지방간질환 진단 방법
WO2019159154A1 (en) * 2018-02-19 2019-08-22 Bruker France Sas Nuclear spin hyperpolarization in a porous matrix
CN117180458B (zh) * 2023-08-31 2024-08-09 中国科学院精密测量科学与技术创新研究院 草酰乙酸在溶融动态核极化中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6009342A (en) * 1997-02-28 1999-12-28 The Regents Of The University Of California Imaging method for the grading of tumors
ATE276745T1 (de) * 1998-04-09 2004-10-15 Amersham Health As Verwendung von teilchenförmigen kontrastmitteln in der diagnostischen bilderzeugung zur untersuchung physiologischer parameter
US7742800B2 (en) * 2004-05-10 2010-06-22 General Electric Company Methods and systems for detection and monitoring of neurodegenerative diseases using magnetic resonance spectroscopy
CA2576202A1 (en) * 2004-07-30 2006-02-02 Ge Healthcare As Mr imaging method for the discrimination between healthy and tumour tissue
AU2005267668B2 (en) * 2004-07-30 2011-10-20 Ge Healthcare As Method of producing a composition, composition and its use
PL1824523T3 (pl) * 2004-11-19 2013-12-31 Ge Healthcare As Sposób obrazowania serca przy zastosowaniu hiperspolaryzowanego 13C-pirogronianu

Also Published As

Publication number Publication date
KR20150053819A (ko) 2015-05-18
EP2144561B1 (en) 2017-09-20
KR20100023802A (ko) 2010-03-04
CA2683023A1 (en) 2008-11-27
AU2008253822A1 (en) 2008-11-27
EP2144561A1 (en) 2010-01-20
CN101730504A (zh) 2010-06-09
WO2008143519A1 (en) 2008-11-27
RU2494672C2 (ru) 2013-10-10
MX2009011855A (es) 2009-11-18
AU2008253822B2 (en) 2013-01-31
RU2009137467A (ru) 2011-06-27
CN105054933A (zh) 2015-11-18
CA2683023C (en) 2016-10-11
JP2010529868A (ja) 2010-09-02
US20110020235A1 (en) 2011-01-27

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Legal Events

Date Code Title Description
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2514 DE 12-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.