BRPI0811511A2 - Paliperidona pura e processos para sua preparação - Google Patents
Paliperidona pura e processos para sua preparaçãoInfo
- Publication number
- BRPI0811511A2 BRPI0811511A2 BRPI0811511-7A2A BRPI0811511A BRPI0811511A2 BR PI0811511 A2 BRPI0811511 A2 BR PI0811511A2 BR PI0811511 A BRPI0811511 A BR PI0811511A BR PI0811511 A2 BRPI0811511 A2 BR PI0811511A2
- Authority
- BR
- Brazil
- Prior art keywords
- processes
- preparation
- pure paliperidone
- paliperidone
- pure
- Prior art date
Links
- PMXMIIMHBWHSKN-UHFFFAOYSA-N 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCC(O)C4=NC=3C)=NOC2=C1 PMXMIIMHBWHSKN-UHFFFAOYSA-N 0.000 title 1
- 229960001057 paliperidone Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92874707P | 2007-05-10 | 2007-05-10 | |
| US92874507P | 2007-05-10 | 2007-05-10 | |
| US93039207P | 2007-05-15 | 2007-05-15 | |
| US92912607P | 2007-06-14 | 2007-06-14 | |
| US95857107P | 2007-07-05 | 2007-07-05 | |
| US92970307P | 2007-07-10 | 2007-07-10 | |
| US93509407P | 2007-07-26 | 2007-07-26 | |
| US93509307P | 2007-07-26 | 2007-07-26 | |
| US96392207P | 2007-08-07 | 2007-08-07 | |
| US11/889,558 US20080171876A1 (en) | 2007-05-10 | 2007-08-14 | Pure paliperidone and processes for preparing thereof |
| PCT/US2008/002027 WO2008140641A2 (en) | 2007-05-10 | 2008-02-14 | Pure paliperidone and processes for preparing thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0811511A2 true BRPI0811511A2 (pt) | 2014-11-18 |
Family
ID=40002831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0811511-7A2A BRPI0811511A2 (pt) | 2007-05-10 | 2008-02-14 | Paliperidona pura e processos para sua preparação |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20080171876A1 (pt) |
| EP (1) | EP2044069A2 (pt) |
| JP (1) | JP2010526806A (pt) |
| KR (1) | KR20100007874A (pt) |
| CN (1) | CN101679419A (pt) |
| BR (1) | BRPI0811511A2 (pt) |
| IL (1) | IL197004A0 (pt) |
| WO (1) | WO2008140641A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7820816B2 (en) * | 2006-08-23 | 2010-10-26 | Teva Pharmaceutical Industries Ltd. | Process for the synthesis of CMHTP and intermediates thereof |
| US20080171876A1 (en) * | 2007-05-10 | 2008-07-17 | Santiago Ini | Pure paliperidone and processes for preparing thereof |
| US20090209757A1 (en) * | 2008-01-10 | 2009-08-20 | Santiago Ini | Processes for the preparation and purification of paliperidone palmitate |
| EP2202234A1 (en) | 2008-12-24 | 2010-06-30 | Laboratorios Lesvi, S.L. | Purification of paliperidone |
| WO2010122575A2 (en) | 2009-04-20 | 2010-10-28 | Matrix Laboratories Ltd | Process for the preparation of pure paliperidone |
| US20120164188A1 (en) | 2009-09-10 | 2012-06-28 | Actavis Group Ptc Ehf | Paliperidone or a pharmaceutically acceptable salt thereof substantially free of impurities |
| EP2343296A1 (en) * | 2009-12-01 | 2011-07-13 | Chemo Ibérica, S.A. | A process for the purification of paliperidone |
| WO2011073997A2 (en) | 2009-12-14 | 2011-06-23 | Cadila Healthcare Limited | Process for preparing paliperidone and pharmaceutically acceptable salts thereof |
| WO2012035554A1 (en) | 2010-09-14 | 2012-03-22 | Megafine Pharma (P) Ltd. | An improved process for the preparation of highly pure paliperidone |
| EP2714687B1 (en) | 2011-05-30 | 2017-02-15 | Cipla Limited | Process for the preparation of paliperidone |
| CN111533737A (zh) * | 2020-05-22 | 2020-08-14 | 烟台大学 | 4-氟帕利哌酮棕榈酸酯及其制备方法和应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US150046A (en) * | 1874-04-21 | Improvement in shoemakers awl-hafts | ||
| US60027A (en) * | 1866-11-27 | mason | ||
| US260303A (en) * | 1882-06-27 | Lantern-holder | ||
| US2698846A (en) * | 1953-04-24 | 1955-01-04 | Hoffmann La Roche | Heterocyclic compounds |
| US5158952A (en) * | 1988-11-07 | 1992-10-27 | Janssen Pharmaceutica N.V. | 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use |
| US5254556A (en) * | 1988-11-07 | 1993-10-19 | Janssen Pharmaceutica N.V. | 3-piperidinyl-1,2-benzisoxazoles |
| US5193214A (en) * | 1989-12-29 | 1993-03-09 | Robert Bosch Gmbh | Vehicular radio receiver with standard traffic problem database |
| AU687940B2 (en) * | 1993-11-23 | 1998-03-05 | Janssen Pharmaceutica N.V. | Novel 9-hydroxy-pyrido(1,2-a)pyrimidin-4-one ether derivatives |
| SE516278C2 (sv) * | 1994-03-04 | 2001-12-10 | Volvo Ab | Trafikinformationssystem och förfarande för tillhandahållande av trafikinformation |
| US6325826B1 (en) * | 1998-01-14 | 2001-12-04 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
| JP3532492B2 (ja) * | 1999-06-25 | 2004-05-31 | 株式会社ザナヴィ・インフォマティクス | 道路交通情報提供システム、情報提供装置、およびナビゲーション装置 |
| JP2003004455A (ja) * | 2001-06-15 | 2003-01-08 | Mitsubishi Electric Corp | 車載用ナビゲーション装置 |
| US6843880B2 (en) * | 2002-05-24 | 2005-01-18 | International Business Machines Corporation | Enhanced endpoint detection for wet etch process control |
| WO2006027370A1 (en) * | 2004-09-09 | 2006-03-16 | Janssen Pharmaceutica N.V. | PREPARATION OF 9-HYDROXY-3- (2-HYDROXYETHYL) -2-METHYL-4H-PYRID0[1, 2-a] PYRIMIDIN-4-ONE AND CRYSTALS THEREOF |
| CN101163702B (zh) * | 2005-04-25 | 2011-09-07 | 詹森药业有限公司 | 制备无菌的3-[2-[4-(6-氟-1,2-苯并异唑-3-基)-1-哌啶基]乙基]-6,7,8,9-四氢-9-羟基-2-甲基-4H-吡啶并[1,2-a]嘧啶-4-酮棕榈酸酯的方法 |
| US7453755B2 (en) * | 2005-07-01 | 2008-11-18 | Sandisk 3D Llc | Memory cell with high-K antifuse for reverse bias programming |
| US7915412B2 (en) * | 2006-08-14 | 2011-03-29 | Teva Pharmaceutical Industries, Ltd. | Process for the synthesis of 9-hydroxy risperidone (paliperidone) |
| JP2009524685A (ja) * | 2006-08-14 | 2009-07-02 | テバ ファーマシューティカル インダストリーズ リミティド | ９−ヒドロキシ−リスペリドン（パリペリドン）の結晶型 |
| US7820816B2 (en) * | 2006-08-23 | 2010-10-26 | Teva Pharmaceutical Industries Ltd. | Process for the synthesis of CMHTP and intermediates thereof |
| JP2009524574A (ja) * | 2006-08-23 | 2009-07-02 | テバ ファーマシューティカル インダストリーズ リミティド | Ｃｍｈｔｐ及びその中間体の合成方法 |
| US20080171876A1 (en) * | 2007-05-10 | 2008-07-17 | Santiago Ini | Pure paliperidone and processes for preparing thereof |
-
2007
- 2007-08-14 US US11/889,558 patent/US20080171876A1/en not_active Abandoned
-
2008
- 2008-02-14 EP EP08725638A patent/EP2044069A2/en not_active Withdrawn
- 2008-02-14 JP JP2010507383A patent/JP2010526806A/ja active Pending
- 2008-02-14 KR KR1020097023453A patent/KR20100007874A/ko not_active Ceased
- 2008-02-14 WO PCT/US2008/002027 patent/WO2008140641A2/en not_active Ceased
- 2008-02-14 CN CN200880015395A patent/CN101679419A/zh active Pending
- 2008-02-14 BR BRPI0811511-7A2A patent/BRPI0811511A2/pt not_active IP Right Cessation
- 2008-02-14 US US12/070,130 patent/US20080281100A1/en not_active Abandoned
-
2009
- 2009-02-11 IL IL197004A patent/IL197004A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010526806A (ja) | 2010-08-05 |
| IL197004A0 (en) | 2009-11-18 |
| WO2008140641A3 (en) | 2009-03-05 |
| EP2044069A2 (en) | 2009-04-08 |
| US20080171876A1 (en) | 2008-07-17 |
| WO2008140641A2 (en) | 2008-11-20 |
| US20080281100A1 (en) | 2008-11-13 |
| CN101679419A (zh) | 2010-03-24 |
| KR20100007874A (ko) | 2010-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |