BRPI0811710A2 - Troca de nucleotídeo alvo com oligonucleotídes modificados melhorados - Google Patents

Troca de nucleotídeo alvo com oligonucleotídes modificados melhorados

Info

Publication number
BRPI0811710A2
BRPI0811710A2 BRPI0811710-1A2A BRPI0811710A BRPI0811710A2 BR PI0811710 A2 BRPI0811710 A2 BR PI0811710A2 BR PI0811710 A BRPI0811710 A BR PI0811710A BR PI0811710 A2 BRPI0811710 A2 BR PI0811710A2
Authority
BR
Brazil
Prior art keywords
target nucleotide
modified oligonucleotides
nucleotide exchange
improved modified
improved
Prior art date
Application number
BRPI0811710-1A2A
Other languages
English (en)
Inventor
Paul Bundock
Original Assignee
Keygene Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keygene Nv filed Critical Keygene Nv
Publication of BRPI0811710A2 publication Critical patent/BRPI0811710A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01—Transketolases and transaldolases (2.2.1)
    • C12Y202/01006—Acetolactate synthase (2.2.1.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0811710-1A2A 2007-06-22 2008-06-19 Troca de nucleotídeo alvo com oligonucleotídes modificados melhorados BRPI0811710A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2007000159 2007-06-22
PCT/NL2008/000151 WO2009002150A1 (en) 2007-06-22 2008-06-19 Targeted nucleotide exchange with improved modified oligonucleotides

Publications (1)

Publication Number Publication Date
BRPI0811710A2 true BRPI0811710A2 (pt) 2014-10-14

Family

ID=38556385

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811710-1A2A BRPI0811710A2 (pt) 2007-06-22 2008-06-19 Troca de nucleotídeo alvo com oligonucleotídes modificados melhorados

Country Status (12)

Country Link
US (1) US20100223691A1 (pt)
EP (1) EP2167660A1 (pt)
JP (1) JP5467999B2 (pt)
KR (1) KR20100051795A (pt)
CN (1) CN101868542A (pt)
AU (1) AU2008269778A1 (pt)
BR (1) BRPI0811710A2 (pt)
CA (1) CA2690510A1 (pt)
IL (1) IL202530A0 (pt)
NZ (1) NZ582721A (pt)
RU (1) RU2010101882A (pt)
WO (1) WO2009002150A1 (pt)

Families Citing this family (29)

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Publication number Priority date Publication date Assignee Title
AR025996A1 (es) 1999-10-07 2002-12-26 Valigen Us Inc Plantas no transgenicas resistentes a los herbicidas.
UA99594C2 (en) 2006-01-12 2012-09-10 Сайбас Юроп Б.В. Epsps mutants
CA2708751A1 (en) 2007-12-14 2009-06-25 Minitube Of America, Inc. Gender-specific separation of sperm cells and embryos
BRPI0722219A2 (pt) 2007-12-21 2014-08-05 Keygene Nv "um método de mutagênese melhorando utilizando a introdução de nucleobases mutagênicas mediada por polietileno glicol em protoplastos vegetais"
WO2011032034A2 (en) 2009-09-10 2011-03-17 University Of Idaho Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids
AU2010335107B2 (en) 2009-12-21 2014-07-03 Keygene N.V. Improved techniques for transfecting protoplasts
CA2819423C (en) * 2010-12-02 2020-12-22 Keygene N.V. Targeted alteration of dna
EP2655629B1 (en) 2010-12-24 2024-04-24 BASF Agricultural Solutions Seed US LLC Brassica plant comprising a mutant alcatraz allele
US20140206850A1 (en) 2011-04-29 2014-07-24 Keygene N.V. Glyphosate resistance enhancement
WO2013013068A2 (en) 2011-07-19 2013-01-24 University Of Idaho Embodiments of a probe and method for targeting nucleic acids
EP2554045A1 (en) 2011-08-04 2013-02-06 Rijk Zwaan Zaadteelt en Zaadhandel B.V. Method for systemically influencing processes in the male meiocyte
CA3195951A1 (en) 2012-07-06 2014-01-09 BASF Agricultural Solutions Seed US LLC Brassica rod1 gene sequences and uses thereof
CA2878287A1 (en) 2012-07-06 2014-01-09 Bayer Cropscience Nv Soybean rod1 gene sequences and uses thereof
EP2877583A1 (en) 2012-07-06 2015-06-03 Bayer CropScience NV Brassica plants with modified seed oil composition
AU2014247081B2 (en) 2013-04-05 2020-04-16 BASF Agricultural Solutions Seed US LLC Brassica plants comprising mutant DA1 alleles
WO2014201306A1 (en) * 2013-06-12 2014-12-18 Oncoimmunin, Inc. Systemic in vivo delivery of oligonucleotides
CA2917105C (en) 2013-07-01 2023-09-26 Bayer Cropscience Nv Methods and means for modulating flowering time in monocot plants
RU2697502C2 (ru) 2014-07-24 2019-08-14 Эбботт Молекьюлар Инк. Композиции и способы обнаружения и анализа микобактерии туберкулеза (mycobacterium tuberculosis)
WO2016050512A1 (en) 2014-10-03 2016-04-07 Bayer Cropscience Nv Methods and means for increasing stress tolerance and biomass in plants
EP3201327B1 (en) 2014-10-03 2018-10-03 VIB vzw Functional mutant alleles of ein5 for yield increase
CA2983893A1 (en) 2015-04-28 2016-11-03 Bayer Cropscience Nv Brassica plants with modified seed oil composition
EP3322483A4 (en) 2015-07-14 2019-01-02 Abbott Molecular Inc. Compositions and methods for identifying drug resistant tuberculosis
JP2018532405A (ja) 2015-10-16 2018-11-08 バイエル・クロップサイエンス・エヌ・ヴェーＢａｙｅｒ Ｃｒｏｐｓｃｉｅｎｃｅ Ｎ．Ｖ． 種子製造における変更された特性を有するアブラナ属植物
US20200362366A1 (en) 2018-01-12 2020-11-19 Basf Se Gene underlying the number of spikelets per spike qtl in wheat on chromosome 7a
NL2020823B1 (en) 2018-04-25 2019-11-05 Univ Delft Tech NAD+ dependent 7ß-hydroxysteroid dehydrogenase
US12584140B2 (en) 2018-07-12 2026-03-24 Keygene N.V. Type V CRISPR/nuclease-system for genome editing in plant cells
CA3110651A1 (en) 2018-09-07 2020-03-12 Basf Plant Science Company Gmbh Improved method for the production of high levels of pufa in plants
US20220010321A1 (en) 2018-11-01 2022-01-13 Keygene N.V. Dual guide rna for crispr/cas genome editing in plants cells
CN121443735A (zh) * 2023-04-26 2026-01-30 优乐斯治疗株式会社 用于改变靶核苷酸序列的非天然型多核苷酸

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936467B2 (en) * 2000-03-27 2005-08-30 University Of Delaware Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
NZ521698A (en) * 2000-03-27 2004-08-27 Univ Delaware Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
WO2002026967A2 (en) * 2000-09-25 2002-04-04 Thomas Jefferson University Targeted gene correction by single-stranded oligodeoxynucleotides
US20050074801A1 (en) * 2003-09-09 2005-04-07 Monia Brett P. Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry
US20050053981A1 (en) * 2003-09-09 2005-03-10 Swayze Eric E. Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini
WO2007073149A1 (en) * 2005-12-22 2007-06-28 Keygene N.V. Alternative nucleotides for improved targeted nucleotide exchange

Also Published As

Publication number Publication date
JP5467999B2 (ja) 2014-04-09
AU2008269778A1 (en) 2008-12-31
WO2009002150A1 (en) 2008-12-31
US20100223691A1 (en) 2010-09-02
RU2010101882A (ru) 2011-07-27
EP2167660A1 (en) 2010-03-31
NZ582721A (en) 2011-11-25
CN101868542A (zh) 2010-10-20
JP2010530750A (ja) 2010-09-16
KR20100051795A (ko) 2010-05-18
IL202530A0 (en) 2011-08-01
CA2690510A1 (en) 2008-12-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]