BRPI0812233A2 - Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos. - Google Patents

Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos.

Info

Publication number
BRPI0812233A2
BRPI0812233A2 BRPI0812233-4A2A BRPI0812233A BRPI0812233A2 BR PI0812233 A2 BRPI0812233 A2 BR PI0812233A2 BR PI0812233 A BRPI0812233 A BR PI0812233A BR PI0812233 A2 BRPI0812233 A2 BR PI0812233A2
Authority
BR
Brazil
Prior art keywords
euchariotic
organisms
methods
target dna
exact target
Prior art date
Application number
BRPI0812233-4A2A
Other languages
English (en)
Inventor
Anne Rolland
Manuel Dubald
Michiel Van Lookeren Campagne
Rene Ruiter
Original Assignee
Bayer Bioscience Nv
Bayer Cropscience Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Bioscience Nv, Bayer Cropscience Sa filed Critical Bayer Bioscience Nv
Publication of BRPI0812233A2 publication Critical patent/BRPI0812233A2/pt
Publication of BRPI0812233B1 publication Critical patent/BRPI0812233B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0812233-4A 2007-06-05 2008-06-03 Processos para troca de uma sequência de dna-alvo no genoma de uma célula de planta ou planta por uma sequência de dna de interesse, e vetor de dna BRPI0812233B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07010998 2007-06-05
EP07010998.8 2007-06-05
US93381407P 2007-06-08 2007-06-08
US60/933,814 2007-06-08
PCT/EP2008/004524 WO2008148559A1 (en) 2007-06-05 2008-06-03 Methods and means for exact replacement of target dna in eukaryotic organisms

Publications (2)

Publication Number Publication Date
BRPI0812233A2 true BRPI0812233A2 (pt) 2014-10-07
BRPI0812233B1 BRPI0812233B1 (pt) 2022-10-04

Family

ID=39673536

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812233-4A BRPI0812233B1 (pt) 2007-06-05 2008-06-03 Processos para troca de uma sequência de dna-alvo no genoma de uma célula de planta ou planta por uma sequência de dna de interesse, e vetor de dna

Country Status (7)

Country Link
US (1) US8765448B2 (pt)
EP (1) EP2160467B1 (pt)
CN (1) CN101688217B (pt)
AU (1) AU2008258782B2 (pt)
BR (1) BRPI0812233B1 (pt)
CA (1) CA2689345C (pt)
WO (1) WO2008148559A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0816750A2 (pt) 2007-06-29 2015-09-29 Pioneer Hi Bred Int métodos para alterar o genoma de uma célula de planta monocotiledônea e para modificar uma sequência alvo genômica endógena específica e planta de milho
WO2009114321A2 (en) 2008-03-11 2009-09-17 Precision Biosciencs, Inc. Rationally-designed meganucleases for maize genome engineering
MX2010011511A (es) 2008-04-21 2011-06-09 Danziger Innovations Ltd Vectores de expresion viral de planta y uso de los mismos para generar variaciones genotipicas en genomas de plantas.
WO2011048600A1 (en) * 2009-10-21 2011-04-28 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
CN103119169B (zh) 2010-06-09 2018-11-20 拜尔作物科学公司 植物基因组改造中常用的在核苷酸序列上修饰植物基因组的方法和工具
WO2011154158A1 (en) 2010-06-09 2011-12-15 Bayer Bioscience N.V. Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering
CN102559704B (zh) * 2010-12-23 2014-08-27 中国科学院上海生命科学研究院 一种在丙酮丁醇梭菌中敲除基因的方法
EP2689019A2 (en) * 2011-03-23 2014-01-29 Pioneer Hi-Bred International Inc. Methods for producing a complex transgenic trait locus
ES2657825T3 (es) 2011-06-06 2018-03-07 Bayer Cropscience Nv Métodos y medios para modificar el genoma de una planta en un sitio preseleccionado
AU2012299691B2 (en) 2011-08-22 2015-01-29 BASF Agricultural Solutions Seed US LLC Methods and means to modify a plant genome
EP2612918A1 (en) 2012-01-06 2013-07-10 BASF Plant Science Company GmbH In planta recombination
CA2871008C (en) 2012-04-23 2022-11-22 Bayer Cropscience Nv Targeted genome engineering in plants
AU2014247151A1 (en) * 2013-04-02 2015-10-08 Bayer Cropscience Nv Targeted genome engineering in eukaryotes
CN105682452B (zh) 2013-09-04 2018-10-16 美国陶氏益农公司 用于在作物中确定供体插入的快速靶向分析
US10077449B2 (en) * 2013-11-04 2018-09-18 Dow Agrosciences Llc Universal donor system for gene targeting
BR112017003757A2 (pt) 2014-09-12 2017-12-26 Du Pont ?plantas de milho, partes de planta de milho ou sementes de milho?
WO2016084084A1 (en) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Nucleic acid constructs for genome editing
WO2017102923A1 (en) 2015-12-15 2017-06-22 Bayer Cropscience Nv Brassicaceae plants resistant to plasmodiophora brassicae (clubroot)
US20190225974A1 (en) 2016-09-23 2019-07-25 BASF Agricultural Solutions Seed US LLC Targeted genome optimization in plants
WO2021141890A1 (en) * 2020-01-09 2021-07-15 Pioneer Hi-Bred International, Inc. Two-step gene swap

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436150A (en) 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
JPH08510375A (ja) 1993-02-12 1996-11-05 ザ・ジョンズ−ホプキンス・ユニバーシティー フラボバクテリウム・オケアノコイテス（ｆｏｋｉ）制限エンドヌクレアーゼの機能ドメイン
EP0790311A1 (en) 1996-02-16 1997-08-20 Centrum Voor Plantenveredelings- En Reproduktieonderzoek Microspore-specific promoter from tobacco
JP2002535995A (ja) 1999-02-03 2002-10-29 ザ チルドレンズ メディカル センター コーポレイション 染色体標的部位での二本鎖ｄｎａ切断の誘導を含む遺伝子修復
DE10131786A1 (de) 2001-07-04 2003-01-16 Sungene Gmbh & Co Kgaa Rekombinationssysteme und Verfahren zum Entfernen von Nukleinsäuresequenzen aus dem Genom eukaryotischer Organismen
US20030232410A1 (en) 2002-03-21 2003-12-18 Monika Liljedahl Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
CN1253568C (zh) * 2002-09-02 2006-04-26 大连科源农业生物工程有限公司 具有生物安全性的植物基因工程操作方法
AU2004208031B2 (en) 2003-01-28 2009-10-08 Cellectis Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
ATE514782T1 (de) 2003-11-18 2011-07-15 Bayer Bioscience Nv Verbesserte gezielte dna insertion in pflanzen
JP5639336B2 (ja) * 2005-04-04 2014-12-10 バイエル・クロップサイエンス・エヌ・ヴェーＢａｙｅｒ Ｃｒｏｐｓｃｉｅｎｃｅ Ｎ．Ｖ． 選ばれたｄｎａ配列を除去するための方法および手段
EP2650366B1 (en) 2005-10-18 2017-03-22 Precision Biosciences Rationally designed meganucleases with altered sequence specificity and DNA-binding affinity
WO2007060495A1 (en) 2005-10-25 2007-05-31 Cellectis I-crei homing endonuclease variants having novel cleavage specificity and use thereof
WO2007049095A1 (en) 2005-10-25 2007-05-03 Cellectis Laglidadg homing endonuclease variants having mutations in two functional subdomains and use thereof
WO2007093836A1 (en) 2006-02-13 2007-08-23 Cellectis Meganuclease variants cleaving a dna target sequence from a xp gene and uses thereof
WO2008037436A1 (en) * 2006-09-28 2008-04-03 Bayer Bioscience N.V. Methods and means for removal of a selected dna sequence

Also Published As

Publication number Publication date
CA2689345A1 (en) 2008-12-11
BRPI0812233B1 (pt) 2022-10-04
EP2160467B1 (en) 2015-10-28
AU2008258782A1 (en) 2008-12-11
CN101688217B (zh) 2013-04-03
CN101688217A (zh) 2010-03-31
CA2689345C (en) 2017-07-11
WO2008148559A1 (en) 2008-12-11
US8765448B2 (en) 2014-07-01
AU2008258782B2 (en) 2013-09-19
EP2160467A1 (en) 2010-03-10
US20100175143A1 (en) 2010-07-08

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE S.A (FR) , BAYER CROPSCIENCE N.V

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE N.V. (BE) , BAYER S.A.S. (FR)

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE N.V. (BE) , BAYER CROPSCIENCE AG

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/06/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE AG (DE) ; BASF AGRICULTURAL SOLUTIONS SEED US LLC (US)

B25A Requested transfer of rights approved

Owner name: BASF AGRICULTURAL SOLUTIONS SEED US LLC (US)

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 18A ANUIDADE.