BRPI0812233A2 - Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos. - Google Patents

Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos.

Info

Publication number
BRPI0812233A2
BRPI0812233A2 BRPI0812233-4A2A BRPI0812233A BRPI0812233A2 BR PI0812233 A2 BRPI0812233 A2 BR PI0812233A2 BR PI0812233 A BRPI0812233 A BR PI0812233A BR PI0812233 A2 BRPI0812233 A2 BR PI0812233A2
Authority
BR
Brazil
Prior art keywords
euchariotic
organisms
methods
target dna
exact target
Prior art date
Application number
BRPI0812233-4A2A
Other languages
English (en)
Inventor
Anne Rolland
Manuel Dubald
Michiel Van Lookeren Campagne
Rene Ruiter
Original Assignee
Bayer Bioscience Nv
Bayer Cropscience Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Bioscience Nv, Bayer Cropscience Sa filed Critical Bayer Bioscience Nv
Publication of BRPI0812233A2 publication Critical patent/BRPI0812233A2/pt
Publication of BRPI0812233B1 publication Critical patent/BRPI0812233B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0812233-4A 2007-06-05 2008-06-03 Processos para troca de uma sequência de dna-alvo no genoma de uma célula de planta ou planta por uma sequência de dna de interesse, e vetor de dna BRPI0812233B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07010998 2007-06-05
EP07010998.8 2007-06-05
US93381407P 2007-06-08 2007-06-08
US60/933,814 2007-06-08
PCT/EP2008/004524 WO2008148559A1 (en) 2007-06-05 2008-06-03 Methods and means for exact replacement of target dna in eukaryotic organisms

Publications (2)

Publication Number Publication Date
BRPI0812233A2 true BRPI0812233A2 (pt) 2014-10-07
BRPI0812233B1 BRPI0812233B1 (pt) 2022-10-04

Family

ID=39673536

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812233-4A BRPI0812233B1 (pt) 2007-06-05 2008-06-03 Processos para troca de uma sequência de dna-alvo no genoma de uma célula de planta ou planta por uma sequência de dna de interesse, e vetor de dna

Country Status (7)

Country Link
US (1) US8765448B2 (pt)
EP (1) EP2160467B1 (pt)
CN (1) CN101688217B (pt)
AU (1) AU2008258782B2 (pt)
BR (1) BRPI0812233B1 (pt)
CA (1) CA2689345C (pt)
WO (1) WO2008148559A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2691440A1 (en) 2007-06-29 2009-01-08 Pioneer Hi-Bred International, Inc. Methods for altering the genome of a monocot plant cell
WO2009114321A2 (en) 2008-03-11 2009-09-17 Precision Biosciencs, Inc. Rationally-designed meganucleases for maize genome engineering
WO2009130695A2 (en) 2008-04-21 2009-10-29 Danziger Innovation Ltd. Plant viral expression vectors and use of same for generating genotypic variations in plant genomes
US9476060B2 (en) 2009-10-21 2016-10-25 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
MX347575B (es) 2010-06-09 2017-05-03 Bayer Cropscience N V * Metodos y medios para modificar un genoma vegetal en una secuencia de nucleotidos usada comunmente en la ingenieria genetica de genomas vegetales.
AU2011264074B2 (en) 2010-06-09 2015-01-22 Bayer Cropscience Nv Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering
CN102559704B (zh) * 2010-12-23 2014-08-27 中国科学院上海生命科学研究院 一种在丙酮丁醇梭菌中敲除基因的方法
AR085533A1 (es) 2011-03-23 2013-10-09 Pioneer Hi Bred Int Metodos de produccion de un locus de rasgos transgenicos complejo
WO2012168124A1 (en) 2011-06-06 2012-12-13 Bayer Cropscience Nv Methods and means to modify a plant genome at a preselected site
BR112014003919A2 (pt) 2011-08-22 2017-03-14 Bayer Cropscience Ag métodos e meios para modificar um genoma de planta
EP2612918A1 (en) 2012-01-06 2013-07-10 BASF Plant Science Company GmbH In planta recombination
CA2871008C (en) * 2012-04-23 2022-11-22 Bayer Cropscience Nv Targeted genome engineering in plants
CN105121650A (zh) * 2013-04-02 2015-12-02 拜尔作物科学公司 真核生物中的靶向基因组工程
BR102014021800B1 (pt) 2013-09-04 2022-03-29 Dow Agrosciences Llc Método para detectar a integração específica de sítio de uma sequência de doador de polinucleotídeo dentro de um sítio-alvo genômico
BR102014027448A8 (pt) * 2013-11-04 2021-08-24 Dow Agrosciences Llc cassete de doador de polinucleotídeo, uso de uma planta, de uma parte de planta, ou de uma célula vegetal compreendendo o referido cassete, e método para integração direcionada do mesmo
BR112017003757A2 (pt) 2014-09-12 2017-12-26 Du Pont ?plantas de milho, partes de planta de milho ou sementes de milho?
CA2968808A1 (en) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Nucleic acid constructs for genome editing
WO2017102923A1 (en) 2015-12-15 2017-06-22 Bayer Cropscience Nv Brassicaceae plants resistant to plasmodiophora brassicae (clubroot)
US20190225974A1 (en) 2016-09-23 2019-07-25 BASF Agricultural Solutions Seed US LLC Targeted genome optimization in plants
CA3167419A1 (en) * 2020-01-09 2021-07-15 Pioneer Hi-Bred International, Inc. Two-step gene swap

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436150A (en) 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
EP0682699B1 (en) 1993-02-12 2003-05-07 The Johns-Hopkins University FUNCTIONAL DOMAINS IN $i(FLAVOBACTERIUM OKEANOKOITES) (FOKI) RESTRICTION ENDONUCLEASE
EP0790311A1 (en) 1996-02-16 1997-08-20 Centrum Voor Plantenveredelings- En Reproduktieonderzoek Microspore-specific promoter from tobacco
AU2982900A (en) 1999-02-03 2000-08-25 Children's Medical Center Corporation Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site
DE10131786A1 (de) * 2001-07-04 2003-01-16 Sungene Gmbh & Co Kgaa Rekombinationssysteme und Verfahren zum Entfernen von Nukleinsäuresequenzen aus dem Genom eukaryotischer Organismen
EP1504092B2 (en) 2002-03-21 2014-06-25 Sangamo BioSciences, Inc. Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
CN1253568C (zh) * 2002-09-02 2006-04-26 大连科源农业生物工程有限公司 具有生物安全性的植物基因工程操作方法
US20060206949A1 (en) 2003-01-28 2006-09-14 Sylvain Arnould Custom-made meganuclease and use thereof
PT2025756E (pt) 2003-11-18 2011-09-28 Bayer Bioscience Nv Inserção direccionada de adn em plantas
JP5639336B2 (ja) 2005-04-04 2014-12-10 バイエル・クロップサイエンス・エヌ・ヴェーＢａｙｅｒ Ｃｒｏｐｓｃｉｅｎｃｅ Ｎ．Ｖ． 選ばれたｄｎａ配列を除去するための方法および手段
DK3246403T3 (da) 2005-10-18 2020-10-26 Prec Biosciences Rationelt designede meganucleaser med ændret sekvens-specificitet og dna-bindende affinitet
WO2007060495A1 (en) 2005-10-25 2007-05-31 Cellectis I-crei homing endonuclease variants having novel cleavage specificity and use thereof
WO2007049095A1 (en) 2005-10-25 2007-05-03 Cellectis Laglidadg homing endonuclease variants having mutations in two functional subdomains and use thereof
WO2007093836A1 (en) 2006-02-13 2007-08-23 Cellectis Meganuclease variants cleaving a dna target sequence from a xp gene and uses thereof
EP2082051B1 (en) 2006-09-28 2016-03-23 Bayer CropScience NV Methods and means for removal of a selected dna sequence

Also Published As

Publication number Publication date
CA2689345C (en) 2017-07-11
BRPI0812233B1 (pt) 2022-10-04
CN101688217A (zh) 2010-03-31
AU2008258782A1 (en) 2008-12-11
US20100175143A1 (en) 2010-07-08
CA2689345A1 (en) 2008-12-11
EP2160467A1 (en) 2010-03-10
AU2008258782B2 (en) 2013-09-19
US8765448B2 (en) 2014-07-01
CN101688217B (zh) 2013-04-03
EP2160467B1 (en) 2015-10-28
WO2008148559A1 (en) 2008-12-11

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE S.A (FR) , BAYER CROPSCIENCE N.V

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE N.V. (BE) , BAYER S.A.S. (FR)

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE N.V. (BE) , BAYER CROPSCIENCE AG

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/06/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE AG (DE) ; BASF AGRICULTURAL SOLUTIONS SEED US LLC (US)

B25A Requested transfer of rights approved

Owner name: BASF AGRICULTURAL SOLUTIONS SEED US LLC (US)

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 18A ANUIDADE.