BRPI0812744A2 - Métodos para melhoramento molecular direcionado por sequência - Google Patents

Métodos para melhoramento molecular direcionado por sequência

Info

Publication number
BRPI0812744A2
BRPI0812744A2 BRPI0812744-1A2A BRPI0812744A BRPI0812744A2 BR PI0812744 A2 BRPI0812744 A2 BR PI0812744A2 BR PI0812744 A BRPI0812744 A BR PI0812744A BR PI0812744 A2 BRPI0812744 A2 BR PI0812744A2
Authority
BR
Brazil
Prior art keywords
sequence
methods
directed molecular
molecular improvement
improvement
Prior art date
Application number
BRPI0812744-1A2A
Other languages
English (en)
Inventor
Stan Dotson
Fenggao Dong
Fred Achard
Sam Eathington
Nengbing Tao
Zoe Mccuddin
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40130462&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0812744(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of BRPI0812744A2 publication Critical patent/BRPI0812744A2/pt
Publication of BRPI0812744B1 publication Critical patent/BRPI0812744B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/13—Plant traits
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Genetics & Genomics (AREA)
  • Library & Information Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computing Systems (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
BRPI0812744-1A 2007-06-08 2008-06-09 Métodos para melhoramento molecular direcionado por sequência BRPI0812744B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94270707P 2007-06-08 2007-06-08
US60/942,707 2007-06-08
PCT/US2008/066263 WO2008154472A2 (en) 2007-06-08 2008-06-09 Methods for sequence-directed molecular breeding

Publications (2)

Publication Number Publication Date
BRPI0812744A2 true BRPI0812744A2 (pt) 2014-12-23
BRPI0812744B1 BRPI0812744B1 (pt) 2024-01-30

Family

ID=40130462

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812744-1A BRPI0812744B1 (pt) 2007-06-08 2008-06-09 Métodos para melhoramento molecular direcionado por sequência

Country Status (9)

Country Link
US (4) US20090136938A1 (pt)
EP (2) EP2158336A2 (pt)
CN (1) CN101802219A (pt)
AR (1) AR066922A1 (pt)
BR (1) BRPI0812744B1 (pt)
CA (1) CA2688644A1 (pt)
CL (1) CL2008001682A1 (pt)
MX (1) MX2009013422A (pt)
WO (1) WO2008154472A2 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR066922A1 (es) 2007-06-08 2009-09-23 Monsanto Technology Llc Metodos de mejoramiento molecular del germoplasma de una planta por secuenciamiento dirigido
CN102206638B (zh) * 2010-03-29 2014-06-04 中国科学院上海生命科学研究院 组织特异表达启动子及其获得方法和应用
UA115766C2 (uk) 2010-12-03 2017-12-26 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Трансгенна стійка до гербіцидів рослина сої, яка містить пакетовану подію 8264.44.06.1
CN103184275A (zh) * 2011-12-29 2013-07-03 天津农学院 一种水稻基因组基因标识的新方法
US10648030B2 (en) * 2012-01-13 2020-05-12 Affymetrix, Inc. Methods of determining the presence or absence of a plurality of target polynucleotides in a sample
CN102622634B (zh) * 2012-03-31 2014-04-23 中国农业科学院果树研究所 一种苹果种质资源条形码标识的制备方法
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
US10314253B2 (en) 2012-12-04 2019-06-11 Seminis Vegetable Seeds, Inc. Methods and compositions for watermelon sex expression
WO2014144092A1 (en) 2013-03-15 2014-09-18 Nugen Technologies, Inc. Sequential sequencing
CA2929596C (en) 2013-11-13 2022-07-05 Nugen Technologies, Inc. Compositions and methods for identification of a duplicate sequencing read
US20150181822A1 (en) 2013-12-31 2015-07-02 Dow Agrosciences Llc Selection based on optimal haploid value to create elite lines
CN107075581B (zh) * 2014-08-06 2022-03-18 纽亘技术公司 由靶向测序进行数字测量
US11118216B2 (en) 2015-09-08 2021-09-14 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
US11708574B2 (en) * 2016-06-10 2023-07-25 Myriad Women's Health, Inc. Nucleic acid sequencing adapters and uses thereof
CA3031231A1 (en) * 2016-08-08 2018-02-15 Karius, Inc. Reduction of signal from contaminant nucleic acids
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
CN108376210B (zh) * 2018-02-12 2020-06-09 中国农业科学院作物科学研究所 基因组信息辅助育种方法ⅱ-一种基于全基因组snp有利单倍型挖掘的育种亲本选择方法
WO2020006475A1 (en) 2018-06-29 2020-01-02 Covariance Biosciences, Llc Methods and compositions for improved multiplex genotyping and sequencing
CN110564832B (zh) * 2019-09-12 2023-06-23 广东省农业科学院动物科学研究所 一种基于高通量测序平台的基因组育种值估计方法与应用
US10927409B1 (en) 2019-10-14 2021-02-23 Pioneer Hi-Bred International, Inc. Detection of sequences uniquely associated with a dna target region
EP3851542A1 (en) 2020-01-20 2021-07-21 Tecan Genomics, Inc. Depletion of abundant uninformative sequences
CN113275053A (zh) 2020-02-03 2021-08-20 帝肯基因组学公司 试剂存储系统
CN111312335B (zh) * 2020-02-24 2023-07-21 吉林省农业科学院 大豆亲本选择方法、装置、存储介质及电子设备
CN112951345B (zh) * 2021-03-10 2022-06-21 中国地质大学（武汉） 基于杂原子化合物进行油-储源定量对比的方法
CN113736905B (zh) * 2021-09-29 2024-11-05 石家庄博瑞迪生物技术有限公司 一种基于mSNP技术检测西瓜种子纯度的混样检测方法
AU2024364136A1 (en) * 2023-10-19 2026-04-23 Monsanto Technology Llc Methods and systems for use in trait development in agricultural crops
CN118923529A (zh) * 2024-05-08 2024-11-12 山东煜盛煌科技发展集团有限公司 一种多穗大粒杂交小麦育种方法

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535060A (en) 1983-01-05 1985-08-13 Calgene, Inc. Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use
EP0146589A4 (en) 1983-05-26 1987-04-29 Plant Resources Inst METHOD FOR GENETIC TOPOGRAPHIC SURVEYING AND HYBRIDIZATION FOR PLANTS.
US4757011A (en) 1983-09-30 1988-07-12 E. I. Du Pont De Nemours And Company Herbicide resistant tobacco
US4940835A (en) 1985-10-29 1990-07-10 Monsanto Company Glyphosate-resistant plants
DE3784860D1 (de) 1986-12-05 1993-04-22 Ciba Geigy Ag Verbessertes verfahren zur transformation von pflanzlichen protoplasten.
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
US4971908A (en) 1987-05-26 1990-11-20 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
WO1990004651A1 (en) 1988-10-19 1990-05-03 Whitehead Institute For Biomedical Research Mapping quantitative traits using genetic markers
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
JP3209744B2 (ja) 1990-01-22 2001-09-17 デカルブ・ジェネティクス・コーポレーション 結実能力のある遺伝子変換コーン
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US6403865B1 (en) 1990-08-24 2002-06-11 Syngenta Investment Corp. Method of producing transgenic maize using direct transformation of commercially important genotypes
US5384253A (en) 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
US5492547B1 (en) 1993-09-14 1998-06-30 Dekalb Genetics Corp Process for predicting the phenotypic trait of yield in maize
HU223760B1 (hu) 1991-09-24 2005-01-28 Keygene N.V. Szelektív restrikciós fragmentumsokszorosítás, általános módszer DNS-fingerprint analízisére
US5437697A (en) 1992-07-07 1995-08-01 E. I. Du Pont De Nemours And Company Method to identify genetic markers that are linked to agronomically important genes
DE69334225D1 (de) 1992-07-07 2008-07-31 Japan Tobacco Inc Verfahren zur transformation einer monokotyledon pflanze
US5635055A (en) 1994-07-19 1997-06-03 Exxon Research & Engineering Company Membrane process for increasing conversion of catalytic cracking or thermal cracking units (law011)
US5846719A (en) * 1994-10-13 1998-12-08 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
US5604097A (en) 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US5981840A (en) 1997-01-24 1999-11-09 Pioneer Hi-Bred International, Inc. Methods for agrobacterium-mediated transformation
US6219964B1 (en) 1997-03-20 2001-04-24 E. I. Du Pont De Nemours And Company Method for identifying genetic marker loci associated with trait loci
AU1927599A (en) 1997-12-22 1999-07-12 Pioneer Hi-Bred International, Inc. Qtl mapping in plant breeding populations
CA2359868A1 (en) 1999-01-14 2000-07-20 Monsanto Company Soybean transformation method
US6537635B1 (en) 1999-03-23 2003-03-25 Flexplay Technologies, Inc. Pseudo-reflective read inhibitor for optical storage media
EP1265476A2 (en) 1999-12-30 2002-12-18 Pioneer Hi-Bred International, Inc. Mqm mapping using haplotyped putative qtl-alleles: a simple approach for mapping qtl's in plant breeding populations
US7157564B1 (en) 2000-04-06 2007-01-02 Affymetrix, Inc. Tag nucleic acids and probe arrays
WO2003052101A1 (en) 2001-12-14 2003-06-26 Rosetta Inpharmatics, Inc. Sample tracking using molecular barcodes
US20050204780A1 (en) 2002-05-09 2005-09-22 The Furukawa Electric Co., Ltd. Method for manufacturing optical fiber
JP3961530B2 (ja) 2003-05-23 2007-08-22 富士通株式会社 光学素子、光伝送ユニット及び光伝送システム
EP1626621A4 (en) * 2003-05-28 2009-10-21 Pioneer Hi Bred Int PLANT SELECTION METHOD
US8039686B2 (en) * 2003-07-07 2011-10-18 Pioneer Hi-Bred International, Inc. QTL “mapping as-you-go”
WO2005012576A2 (en) 2003-08-01 2005-02-10 Pioneer Hi-Bred International, Inc. Molecular markers for the selection of soybean plants having superior agronomic performance
US20050064435A1 (en) 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US7328230B2 (en) 2004-03-26 2008-02-05 Intel Corporation SIMD four-data element average instruction
US20060288444A1 (en) 2004-08-13 2006-12-21 Mccarroll Robert Soybean polymorphisms and methods of genotyping
EP2798947B1 (en) 2004-08-26 2020-03-18 Monsanto Technology, LLC Automated seed sampler and method of bulking seeds
US7703238B2 (en) 2004-08-26 2010-04-27 Monsanto Technology Llc Methods of seed breeding using high throughput nondestructive seed sampling
US20060135758A1 (en) 2004-08-31 2006-06-22 Kunsheng Wu Soybean polymorphisms and methods of genotyping
US20060141495A1 (en) 2004-09-01 2006-06-29 Kunsheng Wu Polymorphic markers and methods of genotyping corn
WO2006039449A1 (en) 2004-09-29 2006-04-13 Monsanto Technology Llc High yielding soybean plants with low linolenic acid
US8404927B2 (en) 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
AP2693A (en) 2005-05-27 2013-07-16 Monsanto Technology Llc Soybean event MON89788 and methods for detection thereof
DE602006013831D1 (de) 2005-06-23 2010-06-02 Keygene Nv Verbesserte strategien zur sequenzierung komplexer genome unter verwendung von sequenziertechniken mit hohem durchsatz
CN105039313B (zh) * 2005-06-23 2018-10-23 科因股份有限公司 用于多态性的高通量鉴定和检测的策略
US7485425B2 (en) * 2005-10-03 2009-02-03 Applied Biosystems Inc. Methods for amplification of nucleic acids using spanning primers
AU2006314535A1 (en) * 2005-11-15 2007-05-24 Biogemma EMP4 gene
DK1991698T3 (en) 2006-03-01 2014-03-10 Keygene Nv "High-throughput" -sekvensbaseret detection of SNPs using ligeringsassays
US7998669B2 (en) 2006-03-02 2011-08-16 Monsanto Technology Llc Automated contamination-free seed sampler and methods of sampling, testing and bulking seeds
US20080083042A1 (en) 2006-08-14 2008-04-03 David Butruille Maize polymorphisms and methods of genotyping
EP2056667A1 (en) 2006-08-15 2009-05-13 Monsanto Technology, LLC Compositions and methods of plant breeding using high density marker information
EP2518162B1 (en) * 2006-11-15 2018-03-07 Biospherex LLC Multitag sequencing and ecogenomics analysis
AR066922A1 (es) * 2007-06-08 2009-09-23 Monsanto Technology Llc Metodos de mejoramiento molecular del germoplasma de una planta por secuenciamiento dirigido
CN108611398A (zh) 2012-01-13 2018-10-02 Data生物有限公司 通过新一代测序进行基因分型

Also Published As

Publication number Publication date
AR066922A1 (es) 2009-09-23
US10544471B2 (en) 2020-01-28
US20180004894A1 (en) 2018-01-04
CL2008001682A1 (es) 2008-12-12
MX2009013422A (es) 2010-01-15
EP2511381A1 (en) 2012-10-17
EP2158336A2 (en) 2010-03-03
CN101802219A (zh) 2010-08-11
US10550424B2 (en) 2020-02-04
WO2008154472A2 (en) 2008-12-18
CA2688644A1 (en) 2008-12-18
BRPI0812744B1 (pt) 2024-01-30
US20130123113A1 (en) 2013-05-16
EP2511381B1 (en) 2017-01-25
US20160098515A1 (en) 2016-04-07
US10544448B2 (en) 2020-01-28
US20090136938A1 (en) 2009-05-28
WO2008154472A3 (en) 2009-08-27

Similar Documents

Publication Publication Date Title
BRPI0810984A2 (pt) Micro-descanso extendido para comunicação
BRPI0819127A2 (pt) Método para cimentar.
DE602008002163D1 (de) Spikeloser Reifen
BRPI0815075A2 (pt) Aglutinantes
DE602008001114D1 (de) Spikeloser Reifen
DE602008001482D1 (de) Luftreifen
DE602008001751D1 (de) Luftreifen
BRPI0811786A2 (pt) Acionador para inalador dosimetrado
CR10705A (es) Anticuerpos para linfotoxina-alfa
DE602008001235D1 (de) Luftreifen
BRPI0811939A2 (pt) Tiazóis substituídos por heteroarila
PT2223114T (pt) Calibrante para imunoensaios
BRPI0812741A2 (pt) Método para separação de glóbulos
BRPI0809678A2 (pt) Métodos
DE602008000674D1 (de) Luftreifen
DE602007005796D1 (de) Schneidegerät
BRPI0813972A2 (pt) Biofibra colorida para artigos plásticos
DE602008002664D1 (de) Luftreifen
BRPI0812105A2 (pt) Neramexano para o tratamento de nistagmo
FI8012U1 (fi) Radan katkaisulaite
DE602008000470D1 (de) Luftreifen
ES1065835Y (es) Caperuza para cetreria
ES1066304Y (es) Bisagra para canapes
DE112007003228A5 (de) Temperiervorrichtung
ES1063735Y (es) Testero para persiana

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/06/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.