BRPI0813587A2 - Composto, uso do mesmo, e, composição farmacêutica - Google Patents

Composto, uso do mesmo, e, composição farmacêutica

Info

Publication number: BRPI0813587A2
Authority: BR; Brazil
Prior art keywords: compound; same; pharmaceutical composition; pharmaceutical; composition
Prior art date: 2007-07-16

Application number

BRPI0813587-8A2A

Other languages

English (en)

Inventor

Jiaqiang Cai

Zoran Rankovic

Philip Stephen Jones

David Jonathan Bennett

Xavier Fradera

Original Assignee

Organon Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-16

Filing date

2008-07-14

Publication date

2014-12-30

2008-07-14 Application filed by Organon Nv filed Critical Organon Nv

2014-12-30 Publication of BRPI0813587A2 publication Critical patent/BRPI0813587A2/pt

Links

150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Immunology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0813587-8A2A 2007-07-16 2008-07-14 Composto, uso do mesmo, e, composição farmacêutica BRPI0813587A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07112517		2007-07-16
PCT/EP2008/059172 WO2009010491A1 (en)	2007-07-16	2008-07-14	6-phenyl-1h-imidazo[4,5-c]pyridine-4-carbonitrile derivatives as cathepsin inhibitors

Publications (1)

Publication Number	Publication Date
BRPI0813587A2 true BRPI0813587A2 (pt)	2014-12-30

Family

ID=38846911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0813587-8A2A BRPI0813587A2 (pt)	2007-07-16	2008-07-14	Composto, uso do mesmo, e, composição farmacêutica

Country Status (19)

Country	Link
EP (1)	EP2178873B1 (pt)
JP (1)	JP5371976B2 (pt)
KR (1)	KR20100043235A (pt)
CN (1)	CN101842373B (pt)
AR (1)	AR067530A1 (pt)
AT (1)	ATE492546T1 (pt)
AU (1)	AU2008277679B2 (pt)
BR (1)	BRPI0813587A2 (pt)
CA (1)	CA2693887A1 (pt)
CL (1)	CL2008002082A1 (pt)
DE (1)	DE602008004167D1 (pt)
EC (1)	ECSP109966A (pt)
ES (1)	ES2356279T3 (pt)
IL (1)	IL202769A0 (pt)
PE (1)	PE20091087A1 (pt)
RU (1)	RU2485119C2 (pt)
TW (1)	TW200911803A (pt)
WO (1)	WO2009010491A1 (pt)
ZA (1)	ZA200909132B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7932251B2 (en)	2007-07-16	2011-04-26	N.V. Organon	6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
TW201035094A (en) *	2009-01-16	2010-10-01	Organon Nv	6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
US8026236B2 (en)	2009-01-16	2011-09-27	N.V. Organon	6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
EP2523954B1 (en)	2010-01-15	2014-04-16	Merck Sharp & Dohme B.V.	1h-[1,2,3]triazolo[4,5-c]pyridine-4- carbonitrile derivatives as cathepsin s inhibitors
EP2727920B1 (en)	2011-07-29	2016-11-02	FUJIFILM Corporation	1,5-naphthyridine derivative or salt thereof
CA2870527A1 (en) *	2012-04-17	2013-10-24	Astellas Pharma Inc.	Nitrogenated bicyclic aromatic heterocyclic compound
EP3887376A1 (en)	2018-11-28	2021-10-06	Topadur Pharma AG	Novel dual mode of action soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof
AU2020250933A1 (en)	2019-04-05	2021-10-28	Centre Hospitalier Régional Et Universitaire De Brest	Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning
CA3168146A1 (en)	2020-01-20	2021-07-29	Genzyme Corporation	Therapeutic tyrosine kinase inhibitors for relapsing multiple sclerosis (rms)
EP3858471A1 (en)	2020-01-31	2021-08-04	Novamem AG	Solvent-free production of porous polymer structures
CA3201936A1 (en)	2020-12-10	2022-06-16	Minhua Chen	Crystal form of tolebrutinib and preparation method thereof
IL303834A (en)	2020-12-23	2023-08-01	Genzyme Corp	4-amino-3-(4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-C]pyridin-2-one derivatives and their salts

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA62972C2 (en) *	1997-07-03	2004-01-15		Application of imidazopyrimidins and imidazopyridins for the treatment of neural disorders
GB9921150D0 (en) *	1999-09-07	1999-11-10	Merck Sharp & Dohme	Therapeutic agents
PA8535601A1 (es) *	2000-12-21	2002-11-28	Pfizer	Derivados benzimidazol y piridilimidazol como ligandos para gabaa
GB0121033D0 (en) *	2001-08-30	2001-10-24	Novartis Ag	Organic compounds
SE0201980D0 (sv) *	2002-06-24	2002-06-24	Astrazeneca Ab	Novel compounds
FR2852957B1 (fr) *	2003-03-31	2005-06-10	Sod Conseils Rech Applic	Nouveaux derives d'imidazo-pyridine et leur utilisation en tant que medicament
EP1724264A1 (en) *	2004-03-10	2006-11-22	Ono Pharmaceutical Co., Ltd.	Nitriles and medicinal compositions containing the same as the active ingredient
TW200734338A (en) *	2006-01-16	2007-09-16	Organon Nv	6-Phenyl-1H-imidazo [4,5-c] pyridine-4-carbonitrile derivatives

2008
- 2008-06-18 TW TW097122685A patent/TW200911803A/zh unknown
- 2008-07-14 AU AU2008277679A patent/AU2008277679B2/en not_active Ceased
- 2008-07-14 CA CA2693887A patent/CA2693887A1/en not_active Abandoned
- 2008-07-14 PE PE2008001179A patent/PE20091087A1/es not_active Application Discontinuation
- 2008-07-14 WO PCT/EP2008/059172 patent/WO2009010491A1/en not_active Ceased
- 2008-07-14 BR BRPI0813587-8A2A patent/BRPI0813587A2/pt not_active Application Discontinuation
- 2008-07-14 DE DE602008004167T patent/DE602008004167D1/de active Active
- 2008-07-14 JP JP2010516481A patent/JP5371976B2/ja not_active Expired - Fee Related
- 2008-07-14 EP EP08786128A patent/EP2178873B1/en active Active
- 2008-07-14 ES ES08786128T patent/ES2356279T3/es active Active
- 2008-07-14 AR ARP080103015A patent/AR067530A1/es unknown
- 2008-07-14 AT AT08786128T patent/ATE492546T1/de not_active IP Right Cessation
- 2008-07-14 CN CN200880024871XA patent/CN101842373B/zh not_active Expired - Fee Related
- 2008-07-14 RU RU2010105234/04A patent/RU2485119C2/ru not_active IP Right Cessation
- 2008-07-14 KR KR1020107003287A patent/KR20100043235A/ko not_active Withdrawn
- 2008-07-15 CL CL2008002082A patent/CL2008002082A1/es unknown
2009
- 2009-12-16 IL IL202769A patent/IL202769A0/en unknown
- 2009-12-21 ZA ZA200909132A patent/ZA200909132B/xx unknown
2010
- 2010-02-12 EC EC2010009966A patent/ECSP109966A/es unknown

Also Published As

Publication number	Publication date
CA2693887A1 (en)	2009-01-22
PE20091087A1 (es)	2009-07-20
AU2008277679B2 (en)	2012-11-15
AR067530A1 (es)	2009-10-14
RU2010105234A (ru)	2011-08-27
EP2178873B1 (en)	2010-12-22
JP2010533675A (ja)	2010-10-28
TW200911803A (en)	2009-03-16
IL202769A0 (en)	2010-06-30
EP2178873A1 (en)	2010-04-28
HK1142323A1 (en)	2010-12-03
JP5371976B2 (ja)	2013-12-18
AU2008277679A1 (en)	2009-01-22
WO2009010491A1 (en)	2009-01-22
RU2485119C2 (ru)	2013-06-20
ATE492546T1 (de)	2011-01-15
CN101842373B (zh)	2013-12-18
DE602008004167D1 (en)	2011-02-03
CL2008002082A1 (es)	2009-01-02
ECSP109966A (es)	2010-03-31
ES2356279T3 (es)	2011-04-06
CN101842373A (zh)	2010-09-22
KR20100043235A (ko)	2010-04-28
ZA200909132B (en)	2010-08-25

Legal Events

Date	Code	Title	Description
2015-06-09	B11A	Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
2015-09-08	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]

Publication	Publication Date	Title
BRPI0618904A2 (pt)	2016-09-13	composto, composição farmacêutica, e, uso do composto
BRPI0814593A2 (pt)	2015-01-20	Composto, composição farmacêutica que o contém e uso do composto.
BRPI0821115A2 (pt)	2015-06-16	Composto derivado de aminotriazol, medicamento, composição farmacêutica e uso do composto
BR112012004335A2 (pt)	2015-09-08	composto, composição farmacêutica, e, uso do composto.
BRPI0810696A2 (pt)	2014-10-21	Composto, composição farmacêutica, e, uso de um composto
BRPI0614205A2 (pt)	2016-11-22	composto, composição farmacêutica, e, uso de composto
BRPI0815709A2 (pt)	2017-06-13	composro, composição farmacêutica, e, uso de um composto.
BRPI0813627A2 (pt)	2014-12-23	Peptídio antimicrobiano, composições e métodos de uso
BRPI0806531A2 (pt)	2014-04-22	Composto, composição farmacêutica, agente terapêutico, e, uso do composto.
BRPI0919942A2 (pt)	2014-12-23	Composto, composição farmacêutica, e, uso de um composto
BRPI0907562A2 (pt)	2017-05-23	composto, composição farmacêutica, e, uso de um composto
BRPI0921375A2 (pt)	2015-12-29	composto, composição farmacêutica, e, uso de um composto
BRPI0720124A2 (pt)	2014-03-04	Composições farmacêuticas e seus métodos de uso.
BRPI0912717A2 (pt)	2014-12-23	Composição farmacêutica, e, uso de 5-azacitidina
BRPI0813770A2 (pt)	2014-12-30	Composição, e, uso de uma composição
BRPI0716171A2 (pt)	2013-09-17	composto, composiÇço farmacÊutica e uso de um composto.
BRPI0810161A2 (pt)	2014-12-30	Composto, preparação farmacêutica, composição farmacêutica, e, uso de um composto
BRPI0815190A2 (pt)	2015-03-31	Composto derivado de piridina, composição farmacêutica que o compreende e uso do mesmo
BRPI0609802A2 (pt)	2017-05-02	composto, composição farmacêutica e uso de um composto
BRPI0819299A2 (pt)	2014-10-07	Uso de composição, e, composição contendo proteína
BRPI0812942A2 (pt)	2014-12-16	Composto, composição farmacêutica e uso de um composto
BRPI0921879A2 (pt)	2018-10-16	composto, composição farmacêutica , e, uso de um composto
BRPI0807078A2 (pt)	2014-04-08	Composto, e, formulação farmacêutica
BRPI0810019A2 (pt)	2014-10-14	Composto, composição farmacêutica, e, uso de um composto
BRPI0716698A2 (pt)	2014-02-25	Composto, composição farmacêutica e uso de um composto