BRPI0813823B8 - métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina - Google Patents

métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina

Info

Publication number
BRPI0813823B8
BRPI0813823B8 BRPI0813823A BRPI0813823A BRPI0813823B8 BR PI0813823 B8 BRPI0813823 B8 BR PI0813823B8 BR PI0813823 A BRPI0813823 A BR PI0813823A BR PI0813823 A BRPI0813823 A BR PI0813823A BR PI0813823 B8 BRPI0813823 B8 BR PI0813823B8
Authority
BR
Brazil
Prior art keywords
immunoglobulin
flow filtration
tangential flow
concentrating
producing
Prior art date
Application number
BRPI0813823A
Other languages
English (en)
Inventor
Rosenberg Eva
Winter Gerhard
Hepbildikler Stefan
Kuhne Wolfgang
Original Assignee
Hoffmann La Roche
Ludwig Maximilians Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38562282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0813823(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche, Ludwig Maximilians Univ filed Critical Hoffmann La Roche
Publication of BRPI0813823A2 publication Critical patent/BRPI0813823A2/pt
Publication of BRPI0813823B1 publication Critical patent/BRPI0813823B1/pt
Publication of BRPI0813823B8 publication Critical patent/BRPI0813823B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

filtração de fluxo tangencial variável. a presente invenção refere-se a um método para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial no qual a pressão da transmembrana e o fluxo cruzado são variáveis.
BRPI0813823A 2007-07-17 2008-07-15 métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina BRPI0813823B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07013948.0 2007-07-17
EP07013948 2007-07-17
PCT/EP2008/005766 WO2009010269A1 (en) 2007-07-17 2008-07-15 Variable tangential flow filtration

Publications (3)

Publication Number Publication Date
BRPI0813823A2 BRPI0813823A2 (pt) 2015-01-06
BRPI0813823B1 BRPI0813823B1 (pt) 2018-08-07
BRPI0813823B8 true BRPI0813823B8 (pt) 2021-05-25

Family

ID=38562282

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813823A BRPI0813823B8 (pt) 2007-07-17 2008-07-15 métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina

Country Status (14)

Country Link
US (1) US8633302B2 (pt)
EP (1) EP2170949B1 (pt)
JP (1) JP5432137B2 (pt)
KR (1) KR101215740B1 (pt)
CN (1) CN101754977B (pt)
AU (1) AU2008277886B8 (pt)
BR (1) BRPI0813823B8 (pt)
CA (1) CA2693443C (pt)
ES (1) ES2401820T3 (pt)
IL (1) IL203338A (pt)
MX (1) MX2010000534A (pt)
RU (1) RU2504549C2 (pt)
TW (1) TWI374051B (pt)
WO (1) WO2009010269A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8822655B2 (en) 2009-09-29 2014-09-02 Hoffmann-La Roche Inc. Pre-filtration adjustment of buffer solutes
WO2011039274A1 (en) * 2009-10-01 2011-04-07 F. Hoffmann-La Roche Ag Multistep final filtration
EP2727643A1 (en) 2012-10-31 2014-05-07 Takeda GmbH Cross-flow ultrafiltration device and method for concentration of pharmaceutical compositions
US9439864B2 (en) * 2014-07-07 2016-09-13 Antriabio, Inc. Solvent extraction from biodegradable microparticles
GB201600287D0 (en) 2016-01-07 2016-02-24 Fujifilm Diosynth Biotechnologies Uk Ltd Process
JP2025522984A (ja) * 2022-07-12 2025-07-17 ベイジン スウィッツアランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 限外濾過／透析濾過（ｕｆ／ｄｆ）による高濃縮ｐｄ－１抗体溶液の調製方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256294A (en) * 1990-09-17 1993-10-26 Genentech, Inc. Tangential flow filtration process and apparatus
GB9610992D0 (en) 1996-05-24 1996-07-31 Glaxo Group Ltd Concentrated antibody preparation
US6365395B1 (en) * 2000-11-03 2002-04-02 Millipore Corporation Process for removing protein aggregates and virus from a protein solution
WO2004001007A2 (en) * 2002-06-21 2003-12-31 Idec Pharmaceuticals Corporation Buffered formulations for concentrating antibodies and methods of use thereof
CN1226418C (zh) * 2002-07-12 2005-11-09 广东欧瑞卡生物工程有限公司 天然活性蛋白质和肽的分离纯化方法
CA2516836A1 (en) * 2003-02-24 2004-09-10 Gtc Biotherapeutics, Inc. Methods of tangential flow filtration and an apparatus therefore
AR045614A1 (es) 2003-09-10 2005-11-02 Hoffmann La Roche Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
US20050197496A1 (en) 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
KR100891620B1 (ko) 2004-04-13 2009-04-02 에프. 호프만-라 로슈 아게 항-ｐ-셀렉틴 항체
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
TW200640443A (en) 2005-02-23 2006-12-01 Alcon Inc Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors

Also Published As

Publication number Publication date
JP5432137B2 (ja) 2014-03-05
TW200914120A (en) 2009-04-01
AU2008277886B2 (en) 2013-03-14
AU2008277886A1 (en) 2009-01-22
RU2504549C2 (ru) 2014-01-20
EP2170949A1 (en) 2010-04-07
ES2401820T3 (es) 2013-04-24
KR101215740B1 (ko) 2012-12-27
US20100196961A1 (en) 2010-08-05
RU2010105311A (ru) 2011-08-27
CN101754977A (zh) 2010-06-23
KR20100049066A (ko) 2010-05-11
BRPI0813823A2 (pt) 2015-01-06
TWI374051B (en) 2012-10-11
EP2170949B1 (en) 2012-12-26
CN101754977B (zh) 2013-07-17
JP2010533663A (ja) 2010-10-28
BRPI0813823B1 (pt) 2018-08-07
AU2008277886B8 (en) 2013-08-01
WO2009010269A1 (en) 2009-01-22
US8633302B2 (en) 2014-01-21
MX2010000534A (es) 2010-04-22
CA2693443A1 (en) 2009-01-22
IL203338A (en) 2014-03-31
CA2693443C (en) 2018-02-13

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/07/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF