BRPI0816995A2 - Composições de ciclosporina - Google Patents

Composições de ciclosporina

Info

Publication number: BRPI0816995A2
Authority: BR; Brazil
Prior art keywords: cyclosporine compositions; cyclosporine; compositions
Prior art date: 2007-09-20

Application number

Other languages

English (en)

Inventor

Richard S Graham

Walter L Tier

Aileen Morgan

Rhett Schiffman

David A Hollander

Mayssa Attar

Original Assignee

Allergan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-20

Filing date

2008-09-18

Publication date

2015-03-24

2008-09-18 Application filed by Allergan Inc filed Critical Allergan Inc

2015-03-24 Publication of BRPI0816995A2 publication Critical patent/BRPI0816995A2/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Inorganic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Oncology (AREA)
Biotechnology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

BRPI0816995 2007-09-20 2008-09-18 Composições de ciclosporina BRPI0816995A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11/858,200 US20080146497A1 (en)	2006-07-25	2007-09-20	Cyclosporin Compositions
PCT/US2008/076756 WO2009099467A2 (en)	2007-09-20	2008-09-18	Cyclosporin compositions

Publications (1)

Publication Number	Publication Date
BRPI0816995A2 true BRPI0816995A2 (pt)	2015-03-24

Family

ID=39528114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0816995 BRPI0816995A2 (pt)	2007-09-20	2008-09-18	Composições de ciclosporina

Country Status (12)

Country	Link
US (1)	US20080146497A1 (pt)
EP (1)	EP2190407B1 (pt)
JP (1)	JP2010540446A (pt)
KR (1)	KR20100091946A (pt)
CN (1)	CN101835463A (pt)
AU (1)	AU2008349774A1 (pt)
BR (1)	BRPI0816995A2 (pt)
CA (1)	CA2700182A1 (pt)
IL (1)	IL204614A0 (pt)
MX (1)	MX2010003045A (pt)
RU (1)	RU2010112472A (pt)
WO (1)	WO2009099467A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050059583A1 (en)	2003-09-15	2005-03-17	Allergan, Inc.	Methods of providing therapeutic effects using cyclosporin components
JP5668476B2 (ja)	2007-10-08	2015-02-12	オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃ．	カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物
WO2010127301A1 (en) *	2009-05-01	2010-11-04	Allergan, Inc.	Method of treating allergic conjunctivitis with cyclosporin compositions
EP2440185B1 (en) *	2009-06-09	2015-04-08	Aurinia Pharmaceuticals Inc.	Topical drug delivery systems for ophthalmic use
CN104114154A (zh) *	2011-12-16	2014-10-22	阿勒根公司	包含聚乙烯基己内酰胺-聚乙酸乙烯酯-聚乙二醇接枝共聚物(Soluplus)的眼用组合物
FR2988297B1 (fr) *	2012-03-22	2014-03-28	Thea Lab	Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
WO2013181339A2 (en)	2012-06-01	2013-12-05	Allergan, Inc.	Cyclosporin a analogs
RU2713953C2 (ru)	2014-07-18	2020-02-11	Аллерган, Инк.	Суспензионные составы циклоспорина а для субконъюнктивального и периокулярного введения
KR101587412B1 (ko) *	2014-10-17	2016-01-21	주식회사 휴온스	사이클로스포린 및 트레할로스를 포함하는 안과용 조성물
TW201639873A (zh)	2015-01-08	2016-11-16	歐樂根公司	Ｍｅｂｍｔ側鏈已環化之環孢菌素衍生物
US20190224275A1 (en)	2017-05-12	2019-07-25	Aurinia Pharmaceuticals Inc.	Protocol for treatment of lupus nephritis
RU2762767C1 (ru) *	2020-09-15	2021-12-22	Федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Министерства здравоохранения Российской Федерации	Способ определения тактильной чувствительности роговицы

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2577049B2 (ja) *	1987-06-04	1997-01-29	三共株式会社	シクロスポリン製剤
WO1989001772A1 (en) *	1987-09-03	1989-03-09	University Of Georgia Research Foundation, Inc.	Ocular cyclosporin composition
SG45449A1 (en) *	1992-05-13	1998-01-16	Sandoz Ltd	Ophthalmic compositions
CA2416169C (en) *	2000-07-14	2008-09-23	Allergan, Inc.	Compositions containing therapeutically active components having enhanced solubility
WO2007011880A2 (en) *	2005-07-18	2007-01-25	Minu, L.L.C.	Enhanced ocular neuroprotection/neurostimulation
US7501393B2 (en) *	2005-07-27	2009-03-10	Allergan, Inc.	Pharmaceutical compositions comprising cyclosporins
US8067433B2 (en) *	2005-11-09	2011-11-29	Zalicus Inc.	Methods, compositions, and kits for the treatment of ophthalmic disorders

2007
- 2007-09-20 US US11/858,200 patent/US20080146497A1/en not_active Abandoned
2008
- 2008-09-18 WO PCT/US2008/076756 patent/WO2009099467A2/en not_active Ceased
- 2008-09-18 RU RU2010112472/15A patent/RU2010112472A/ru not_active Application Discontinuation
- 2008-09-18 CN CN200880113223A patent/CN101835463A/zh active Pending
- 2008-09-18 AU AU2008349774A patent/AU2008349774A1/en not_active Abandoned
- 2008-09-18 EP EP08872212.9A patent/EP2190407B1/en not_active Not-in-force
- 2008-09-18 JP JP2010525937A patent/JP2010540446A/ja active Pending
- 2008-09-18 MX MX2010003045A patent/MX2010003045A/es not_active Application Discontinuation
- 2008-09-18 BR BRPI0816995 patent/BRPI0816995A2/pt not_active IP Right Cessation
- 2008-09-18 KR KR1020107008509A patent/KR20100091946A/ko not_active Withdrawn
- 2008-09-18 CA CA2700182A patent/CA2700182A1/en not_active Abandoned
2010
- 2010-03-18 IL IL204614A patent/IL204614A0/en unknown

Also Published As

Publication number	Publication date
WO2009099467A3 (en)	2009-10-22
MX2010003045A (es)	2010-04-29
WO2009099467A2 (en)	2009-08-13
JP2010540446A (ja)	2010-12-24
CA2700182A1 (en)	2009-08-13
CN101835463A (zh)	2010-09-15
IL204614A0 (en)	2010-11-30
RU2010112472A (ru)	2011-10-27
EP2190407B1 (en)	2016-12-07
AU2008349774A1 (en)	2009-08-13
EP2190407A2 (en)	2010-06-02
KR20100091946A (ko)	2010-08-19
US20080146497A1 (en)	2008-06-19

Publication	Publication Date	Title
DK2079456T3 (da)	2013-03-18	Farmaceutiske cyclosporinsammensætninger
ME01423B (me)	2013-12-20	Fungicidni sastavi
HUE059171T2 (hu)	2022-10-28	Kompozíciók
PT2596784T (pt)	2017-03-29	Composições de tapentadol
DK2634232T3 (da)	2022-06-07	Sammensætninger
BRPI0816170A2 (pt)	2015-02-24	Composições poliolefínicas compatibilizadas
BRPI0819737A2 (pt)	2015-06-16	Composições detergentes
DK2209856T3 (da)	2019-10-21	Aerogelsammensætninger
BRPI0813775A2 (pt)	2015-01-06	Composição
BRPI0716325A2 (pt)	2014-03-04	Composição antimicrobianas
RU2493831C3 (ru)	2017-06-08	Фармацевтические композиции
DK2638807T3 (da)	2021-05-25	Drikkevaresammensætninger
ATE528048T1 (de)	2011-10-15	Schweisshemmende/desodorierende zusammensetzung
BRPI0722002A2 (pt)	2018-10-30	composições de desodorante
BRPI0814188A2 (pt)	2014-10-14	Formulações
BRPI0810557A2 (pt)	2016-07-19	composição
EP2043136A4 (en)	2010-08-11	FILMING COMPOSITION
BRPI0811274A2 (pt)	2014-10-07	Composição
DK2235145T3 (da)	2019-05-20	Brændstofsammensætninger
FR2899479B1 (fr)	2009-07-24	Composition cicatrisante
BRPI0716458A2 (pt)	2014-03-04	Composição de vulcanizado
BRPI0718141A2 (pt)	2013-11-05	Composições de frangrâncias
BRPI0719275A2 (pt)	2014-04-29	Composições de carbamatos de fenil-alquil-amino
NO20090054L (no)	2009-01-06	Antitumoral dihydropyran-2-on sammensetninger
EP2197828A4 (en)	2011-09-21	FULLEREN-MULTIADDUKT COMPOSITION

Legal Events

Date	Code	Title	Description
2016-09-20	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 8A ANUIDADE.
2017-01-17	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.