BRPI0819774A2 - Subfamília c de adenovírus sadv-40, -31 e -34 de símio e seus usos - Google Patents

Subfamília c de adenovírus sadv-40, -31 e -34 de símio e seus usos

Info

Publication number
BRPI0819774A2
BRPI0819774A2 BRPI0819774-1A2A BRPI0819774A BRPI0819774A2 BR PI0819774 A2 BRPI0819774 A2 BR PI0819774A2 BR PI0819774 A BRPI0819774 A BR PI0819774A BR PI0819774 A2 BRPI0819774 A2 BR PI0819774A2
Authority
BR
Brazil
Prior art keywords
sadv
subfamily
adenovirus
adenovirus subfamily
Prior art date
Application number
BRPI0819774-1A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Soumitra Roy
James M Wilson
Luc H Vandenberghe
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of BRPI0819774A2 publication Critical patent/BRPI0819774A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0819774-1A2A 2007-11-28 2008-11-24 Subfamília c de adenovírus sadv-40, -31 e -34 de símio e seus usos BRPI0819774A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US449607P 2007-11-28 2007-11-28
US456807P 2007-11-28 2007-11-28
US446507P 2007-11-28 2007-11-28
PCT/US2008/013067 WO2009105084A2 (fr) 2007-11-28 2008-11-24 Adénovirus c de la sous-famille simiesque sadv-40, -31, et -34 et leurs utilisations

Publications (1)

Publication Number Publication Date
BRPI0819774A2 true BRPI0819774A2 (pt) 2014-10-14

Family

ID=40933501

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819774-1A2A BRPI0819774A2 (pt) 2007-11-28 2008-11-24 Subfamília c de adenovírus sadv-40, -31 e -34 de símio e seus usos

Country Status (11)

Country Link
US (1) US8231880B2 (fr)
EP (2) EP2220217A2 (fr)
JP (2) JP5758124B2 (fr)
KR (1) KR101614369B1 (fr)
CN (1) CN102131920B (fr)
AU (1) AU2008350937B2 (fr)
BR (1) BRPI0819774A2 (fr)
CA (1) CA2707029A1 (fr)
MX (1) MX2010005860A (fr)
WO (1) WO2009105084A2 (fr)
ZA (1) ZA201003895B (fr)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102131920B (zh) 2007-11-28 2013-11-06 宾夕法尼亚大学托管会 猿猴亚家族C腺病毒SAdV-40、-31和-34及其应用
CN101883858B (zh) 2007-11-28 2015-07-22 宾夕法尼亚大学托管会 猿猴亚家族E腺病毒SAdV-39、-25.2、-26、-30、-37和-38及其应用
AU2008331905B2 (en) 2007-11-28 2014-09-18 The Trustees Of The University Of Pennsylvania Simian subfamily B adenovirus SAdV-28 and uses thereof
JP5661476B2 (ja) 2008-03-04 2015-01-28 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア サルアデノウイルスＳＡｄＶ−３６、−４２．１、−４２．２および−４４ならびにそれらの用途
WO2010051367A1 (fr) 2008-10-31 2010-05-06 The Trustees Of The University Of Pennsylvania Adénovirus simiens sadv-43, -45, -48, -49 et –50 et leurs utilisations
PL2391638T3 (pl) 2009-02-02 2018-11-30 Glaxosmithkline Biologicals Sa Sekwencje nukleotydowe i aminokwasowe małpiego adenowirusa, zawierające je wektory i ich zastosowania
CA2762203A1 (fr) 2009-05-29 2010-12-02 Soumitra Roy Adenovirus simien 41 et ses utilisations
AU2011332025B2 (en) 2010-11-23 2015-06-25 The Trustees Of The University Of Pennsylvania Subfamily E simian adenoviruses A1321, A1325, A1295, A1309 and A1322 and uses thereof
TWI623618B (zh) 2011-07-12 2018-05-11 傳斯堅公司 Ｈｂｖ聚合酶突變體
WO2013045668A2 (fr) 2011-09-29 2013-04-04 Transgene Sa Composition et schéma immunothérapeutique de traitement d'une infection par le virus de l'hépatite c
TW201318637A (zh) 2011-09-29 2013-05-16 Transgene Sa 免疫療法組成物及用於治療ｃ型肝炎病毒感染之療程（一）
SG11201407343XA (en) 2012-05-18 2014-12-30 Univ Pennsylvania Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
US10473668B2 (en) * 2014-06-06 2019-11-12 The Regents Of The University Of California Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette
EP3151866B1 (fr) 2014-06-09 2023-03-08 Voyager Therapeutics, Inc. Capsides chimériques
KR102608590B1 (ko) 2014-09-24 2023-12-01 솔크 인스티튜트 포 바이올로지칼 스터디즈 종양 살상 바이러스 및 이의 사용방법
US10941452B2 (en) 2014-10-06 2021-03-09 The Trustees Of The University Of Pennsylvania Compositions and methods for isolation of circulating tumor cells (CTC)
RU2716991C2 (ru) 2014-11-05 2020-03-17 Вояджер Терапьютикс, Инк. Полинуклеотиды aadc для лечения болезни паркинсона
KR20230145206A (ko) 2014-11-14 2023-10-17 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
WO2016077687A1 (fr) 2014-11-14 2016-05-19 Voyager Therapeutics, Inc. Compositions et méthodes de traitement de la sclérose latérale amyotrophique (sla)
US11697825B2 (en) 2014-12-12 2023-07-11 Voyager Therapeutics, Inc. Compositions and methods for the production of scAAV
EP4523756A3 (fr) 2015-02-13 2025-05-28 Transgene Vaccin et polythérapie à base d'anticorps immunothérapeutiques
WO2016131945A1 (fr) 2015-02-20 2016-08-25 Transgene Sa Produit de combinaison modulateur de l'autophagie
GB201514772D0 (en) * 2015-08-19 2015-09-30 Glaxosmithkline Biolog Sa Adenovirus polynucleotides and polypeptides
BE1024824B1 (fr) * 2015-06-12 2018-07-13 Glaxosmithkline Biologicals Sa Polynucleotides et polypeptides d'adenovirus
BR112017026523A2 (pt) * 2015-06-12 2018-08-14 Glaxosmithkline Biologicals Sa vetor recombinante, adenovírus recombinante, composição, uso de um vetor recombinante, de um adenovírus recombinante ou de uma composição, método para induzir uma resposta imune em um indivíduo, e, polinucleotídeo isolado.
GB201513176D0 (en) * 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
EP3384035A4 (fr) 2015-12-02 2019-08-07 Voyager Therapeutics, Inc. Dosages pour la détection d'anticorps neutralisants de vaa
WO2017147269A1 (fr) 2016-02-23 2017-08-31 Salk Institute For Biological Studies Expression de gènes exogènes dans un adénovirus thérapeutique pour un effet minimal sur la cinétique virale
WO2017147265A1 (fr) 2016-02-23 2017-08-31 Salk Institute For Biological Studies Dosage à haut débit pour mesurer la cinétique de réplication d'un adénovirus
US11299751B2 (en) 2016-04-29 2022-04-12 Voyager Therapeutics, Inc. Compositions for the treatment of disease
EP3448874A4 (fr) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. Compositions pour le traitement de maladies
CA3023022A1 (fr) 2016-05-04 2017-11-09 Transgene Sa Polytherapie avec un ligand de tlr9 cpg
KR20240056729A (ko) 2016-05-18 2024-04-30 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
KR102427379B1 (ko) 2016-05-18 2022-08-02 보이저 테라퓨틱스, 인크. 헌팅톤 질환을 치료하기 위한 조성물 및 방법
WO2018044933A1 (fr) 2016-08-30 2018-03-08 The Regents Of The University Of California Procédés de ciblage et d'administration biomédicaux, et dispositifs et systèmes pour la mise en œuvre de ceux-ci
WO2018069316A2 (fr) 2016-10-10 2018-04-19 Transgene Sa Polythérapie à base d'un produit immunothérapeutique et de modulateurs de mdsc
GB201620968D0 (en) 2016-12-09 2017-01-25 Glaxosmithkline Biologicals Sa Adenovirus polynucleotides and polypeptides
ES2959811T3 (es) * 2016-12-09 2024-02-28 Glaxosmithkline Biologicals Sa Construcciones de adenovirus de chimpancé con antígenos de Lyssavirus
EP3532082A4 (fr) 2016-12-12 2020-08-26 Salk Institute for Biological Studies Adénovirus synthétiques ciblant une tumeur et leurs utilisations
JP2020518259A (ja) 2017-05-05 2020-06-25 ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ハンチントン病治療組成物および方法
JP2020518258A (ja) 2017-05-05 2020-06-25 ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 筋萎縮性側索硬化症（ａｌｓ）治療組成物および方法
JOP20190269A1 (ar) 2017-06-15 2019-11-20 Voyager Therapeutics Inc بولي نوكليوتيدات aadc لعلاج مرض باركنسون
CA3070087A1 (fr) 2017-07-17 2019-01-24 Voyager Therapeutics, Inc. Systeme de guide de trajectoire d'appareillage en reseau
EP3808849A1 (fr) 2017-08-03 2021-04-21 Voyager Therapeutics, Inc. Compositions et procédés pour l'administration d'aav
AU2018338728B2 (en) 2017-09-29 2025-01-02 Centre National De La Recherche Scientifique (Cnrs) Rescue of central and peripheral neurological phenotype of Friedreich's Ataxia by intravenous delivery
TW202413649A (zh) 2017-10-16 2024-04-01 美商航海家醫療公司 肌萎縮性脊髓側索硬化症(als)之治療
EP3697908A1 (fr) 2017-10-16 2020-08-26 Voyager Therapeutics, Inc. Traitement de la sclérose latérale amyotrophique (sla)
WO2019086466A1 (fr) * 2017-10-31 2019-05-09 Janssen Vaccines & Prevention B.V. Adénovirus et utilisations associées
CN112292449A (zh) 2018-04-09 2021-01-29 萨克生物研究学院 具有增强的复制特性的溶瘤腺病毒组合物
KR20210019996A (ko) 2018-05-15 2021-02-23 보이저 테라퓨틱스, 인크. 파킨슨병의 치료를 위한 조성물 및 방법
WO2019241486A1 (fr) 2018-06-13 2019-12-19 Voyager Therapeutics, Inc. Régions 5' non traduites (5'utr) modifiées pour la production d'aav
CN112770812A (zh) 2018-07-24 2021-05-07 沃雅戈治疗公司 产生基因治疗制剂的系统和方法
EP3856762A1 (fr) 2018-09-28 2021-08-04 Voyager Therapeutics, Inc. Constructions d'expression de frataxine comprenant des promoteurs modifiés et leurs méthodes d'utilisation
WO2020072849A1 (fr) 2018-10-04 2020-04-09 Voyager Therapeutics, Inc. Procédés de mesure du titre et de la puissance de particules de vecteur viral
WO2020072844A1 (fr) 2018-10-05 2020-04-09 Voyager Therapeutics, Inc. Constructions d'acides nucléiques modifiés codant pour des protéines de production d'aav
CN113166781A (zh) 2018-10-15 2021-07-23 沃雅戈治疗公司 在杆状病毒/Sf9系统中大规模生产rAAV的表达载体
WO2020160508A1 (fr) 2019-01-31 2020-08-06 Oregon Health & Science University Méthodes d'utilisation d'une évolution dirigée, dépendant d'une transcription, de capsides aav
CN116322740A (zh) 2020-07-13 2023-06-23 特兰斯吉恩股份有限公司 免疫抑制的治疗
WO2022165313A1 (fr) 2021-02-01 2022-08-04 Regenxbio Inc. Thérapie génique de céroïdes-lipofuscinoses neuronales
WO2022218997A1 (fr) 2021-04-12 2022-10-20 Centre National De La Recherche Scientifique (Cnrs) Nouveau système de présentation de vaccin universel
JP2024518553A (ja) * 2021-05-13 2024-05-01 フォージ バイオロジクス，インコーポレイテッド アデノウイルスヘルパープラスミド
WO2023213764A1 (fr) 2022-05-02 2023-11-09 Transgene Polypeptide de fusion comprenant un anti-pd-l1 sdab et un membre du tnfsf
CN115947798B (zh) * 2022-11-21 2026-04-03 广西壮族自治区兽医研究所 与LMH细胞免疫应答相关的蛋白质pX及其相关生物材料和应用
US20250276095A1 (en) 2024-03-04 2025-09-04 Kate Therapeutics, Inc. Adeno-associated virus compositions for the treatment of duchenne muscular dystrophy
WO2025226841A1 (fr) 2024-04-24 2025-10-30 Kate Therapeutics, Inc. Approche de thérapie génique pour le traitement de troubles associés à tnnt2
WO2025226842A1 (fr) 2024-04-24 2025-10-30 Kate Therapeutics, Inc. Contrôle d'expression par des arnmi exprimés par drg
WO2026011008A1 (fr) 2024-07-02 2026-01-08 Kate Therapeutics, Inc. Contrôle d'expression par miarn exprimés par les muscles squelettiques
WO2026011009A1 (fr) 2024-07-02 2026-01-08 Kate Therapeutics, Inc. Compositions et procédés pour troubles musculaires
WO2026030242A1 (fr) 2024-07-29 2026-02-05 Kate Therapeutics, Inc. Compositions de virus adéno-associés pour le traitement de la dystrophie musculaire facio-scapulo-humérale
WO2026030244A1 (fr) 2024-07-30 2026-02-05 Kate Therapeutics, Inc. Compositions de virus adéno-associés pour le traitement de la dystrophie musculaire des ceintures de type 2a
WO2026050402A1 (fr) 2024-08-29 2026-03-05 Kate Therapeutics, Inc. Capsides tropiques musculaires dé-ciblées du foie

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5240846A (en) 1989-08-22 1993-08-31 The Regents Of The University Of Michigan Gene therapy vector for cystic fibrosis
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
WO1996012406A1 (fr) 1994-10-19 1996-05-02 Genetic Therapy, Inc. Therapie genique par administration concurrente et repetee d'adenovirus et d'agents immunodepresseurs
US5856152A (en) 1994-10-28 1999-01-05 The Trustees Of The University Of Pennsylvania Hybrid adenovirus-AAV vector and methods of use therefor
DE69534166T2 (de) 1994-10-28 2006-03-09 Trustees Of The University Of Pennsylvania Rekombinanter adenovirus und methoden zu dessen verwendung
DE69636863T2 (de) 1995-02-24 2007-11-15 Trustees Of The University Of Pennsylvania Benutzung von immunmodulatoren zur herstellung von medikamenten zur inhibierung einer immunantwort gegen gleichzeitig verabreichte rekombinante viren
WO1998010087A1 (fr) 1996-09-06 1998-03-12 Trustees Of The University Of Pennsylvania Vecteurs d'adenovirus de chimpanze
EP0931158A1 (fr) 1996-09-06 1999-07-28 The Trustees Of The University Of Pennsylvania Procede inductible de production de virus adeno-associes recombines au moyen de la polymerase t7
US5922315A (en) 1997-01-24 1999-07-13 Genetic Therapy, Inc. Adenoviruses having altered hexon proteins
US5891994A (en) 1997-07-11 1999-04-06 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
EP1015619A1 (fr) 1997-09-19 2000-07-05 The Trustees Of The University Of Pennsylvania Procedes et lignee cellulaire utiles pour la production de virus adeno-associes recombines
WO1999014354A1 (fr) 1997-09-19 1999-03-25 The Trustees Of The University Of The Pennsylvania Procedes et produits genetiques vectoriels utiles pour obtenir un virus adeno-associe (aav)
GB9720585D0 (en) 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
AU1822499A (en) 1997-12-12 1999-06-28 Saint Louis University Ctip, a novel protein that interacts with ctbp and uses therefor
EP1064393B1 (fr) 1998-03-20 2004-12-29 The Trustees Of The University Of Pennsylvania Compositions et methodes de production de virus adeno-associes recombines sans auxiliaire
WO2000011140A1 (fr) 1998-08-20 2000-03-02 The Wistar Institute Of Anatomy And Biology Techniques permettant d'augmenter l'immunite des muqueuses par l'intermediaire d'un premier vaccin systemique et d'un rappel mucosal
US6258595B1 (en) 1999-03-18 2001-07-10 The Trustees Of The University Of Pennsylvania Compositions and methods for helper-free production of recombinant adeno-associated viruses
BR0107972A (pt) 2000-01-31 2002-11-05 Smithkline Beecham Biologicals Uso de uma proteìna ou polinucleotìdeo tat do hiv, nef do hiv, ou tat do hiv ligado(a) a uma proteìna ou polinucleotìdeo nef do hiv (nef-tat), e de uma proteìna ou polinucleotìdeo gp120 do hiv, método para imunizar um ser humano contra o hiv, e, composição de vacina para o uso humano
AU2001234981A1 (en) 2000-02-09 2001-08-20 Genvec, Inc. Adenoviral capsid containing chimeric protein ix
EP1409748B1 (fr) * 2001-06-22 2011-10-26 The Trustees of The University of Pennsylvania Adénovirus recombinants comprenant des protéines d'adénovirus simiens et leurs utilisations
US20040136963A1 (en) * 2001-06-22 2004-07-15 The Trustees Of The University Of Pennsylvania Simian adenovirus vectors and methods of use
CN1167801C (zh) * 2001-10-25 2004-09-22 山西德元堂药业有限公司 重组人vegf腺病毒载体及其应用
AU2002365366B2 (en) * 2001-11-21 2007-05-10 The Trustees Of The University Of Pennsylvania Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
CN100475966C (zh) * 2001-11-23 2009-04-08 上海三维生物技术有限公司 具有肿瘤细胞特异性感染和转基因表达能力的新型腺病毒
US7291498B2 (en) * 2003-06-20 2007-11-06 The Trustees Of The University Of Pennsylvania Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
CA2528511C (fr) * 2003-06-20 2015-11-03 The Trustees Of The University Of Pennsylvania Procede pour produire des adenovirus chimeriques et utilisations de ces derniers
DE602005017743D1 (de) * 2004-01-23 2009-12-31 Angeletti P Ist Richerche Bio Impfstoffträger für schimpansen-adenovirus
EP2012822B1 (fr) * 2006-04-28 2010-01-20 The Trustees of the University of Pennsylvania Protéine hexon d'adénovirus modifiée et ses utilisations
CN102131920B (zh) 2007-11-28 2013-11-06 宾夕法尼亚大学托管会 猿猴亚家族C腺病毒SAdV-40、-31和-34及其应用
CN101883858B (zh) 2007-11-28 2015-07-22 宾夕法尼亚大学托管会 猿猴亚家族E腺病毒SAdV-39、-25.2、-26、-30、-37和-38及其应用

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JP2011504751A (ja) 2011-02-17
ZA201003895B (en) 2011-04-28
JP5758124B2 (ja) 2015-08-05
JP2015083007A (ja) 2015-04-30
CN102131920A (zh) 2011-07-20
KR20100105630A (ko) 2010-09-29
MX2010005860A (es) 2010-06-22
EP2463362A1 (fr) 2012-06-13
KR101614369B1 (ko) 2016-04-21
EP2463362B1 (fr) 2017-11-08
CN102131920B (zh) 2013-11-06
US8231880B2 (en) 2012-07-31
US20100260799A1 (en) 2010-10-14
WO2009105084A2 (fr) 2009-08-27
WO2009105084A8 (fr) 2010-10-07
AU2008350937B2 (en) 2014-10-09
AU2008350937A1 (en) 2009-08-27
CA2707029A1 (fr) 2009-08-27
EP2220217A2 (fr) 2010-08-25

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