BRPI0819854A2 - Enumeração e caracterização automatizada de células de melanoma circulantes no sangue - Google Patents
Enumeração e caracterização automatizada de células de melanoma circulantes no sangueInfo
- Publication number
- BRPI0819854A2 BRPI0819854A2 BRPI0819854-3A BRPI0819854A BRPI0819854A2 BR PI0819854 A2 BRPI0819854 A2 BR PI0819854A2 BR PI0819854 A BRPI0819854 A BR PI0819854A BR PI0819854 A2 BRPI0819854 A2 BR PI0819854A2
- Authority
- BR
- Brazil
- Prior art keywords
- characterization
- melanoma cells
- blood circulating
- circulating melanoma
- automated enumeration
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5751—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the skin, e.g. melanoma
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70589—CD45
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US434507P | 2007-11-27 | 2007-11-27 | |
| US61/004,345 | 2007-11-27 | ||
| PCT/US2008/080436 WO2009070392A1 (en) | 2007-11-27 | 2008-10-20 | Automated enumeration and characterization of circulating melanoma cells in blood |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0819854A2 true BRPI0819854A2 (pt) | 2015-06-16 |
| BRPI0819854B1 BRPI0819854B1 (pt) | 2019-06-04 |
Family
ID=40670042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819854-3A BRPI0819854B1 (pt) | 2007-11-27 | 2008-10-20 | Método para isolar, enriquecer e analisar células de melanoma circulantes em uma amostra de sangue |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20090136946A1 (pt) |
| EP (1) | EP2225563B1 (pt) |
| JP (1) | JP5479355B2 (pt) |
| KR (1) | KR101604649B1 (pt) |
| CN (1) | CN101878429B (pt) |
| BR (1) | BRPI0819854B1 (pt) |
| CA (1) | CA2706442C (pt) |
| DK (1) | DK2225563T3 (pt) |
| IL (1) | IL205864A (pt) |
| MX (1) | MX2010005811A (pt) |
| WO (1) | WO2009070392A1 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2359164A4 (en) | 2008-12-10 | 2012-05-30 | Abqmr Inc | CORE MAGNETIC RESONANCE DEVICE, METHOD AND ASSOCIATED TECHNOLOGY |
| WO2010151109A1 (en) * | 2009-06-26 | 2010-12-29 | Erasmus University Medical Center Rotterdam | Identifying circulating tumor cells (ctcs) using cd146 in breast cancers patients |
| US9428547B2 (en) | 2010-04-21 | 2016-08-30 | Dna Electronics, Inc. | Compositions for isolating a target analyte from a heterogeneous sample |
| US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
| US8841104B2 (en) | 2010-04-21 | 2014-09-23 | Nanomr, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
| US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
| TWI539158B (zh) * | 2010-06-08 | 2016-06-21 | 維里德克斯有限責任公司 | 使用血液中之循環黑色素瘤細胞預測黑色素瘤病患之臨床結果的方法。 |
| WO2013013222A1 (en) * | 2011-07-21 | 2013-01-24 | Veridex, Llc | Assay to capture and detect circulating multiple myeloma cells from blood |
| US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
| US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
| US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
| US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
| US9434940B2 (en) | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
| US9804069B2 (en) | 2012-12-19 | 2017-10-31 | Dnae Group Holdings Limited | Methods for degrading nucleic acid |
| PL2972359T3 (pl) | 2013-03-15 | 2021-03-08 | Menarini Silicon Biosystems S.P.A. | Wzbogacanie krążących komórek nowotworowych poprzez deplecję białych krwinek |
| CN103472227A (zh) * | 2013-09-18 | 2013-12-25 | 上海卫恒医疗器械有限公司 | 一种循环肿瘤细胞检测试剂盒、配套仪器及应用 |
| CN107850587B (zh) * | 2015-05-26 | 2021-06-15 | 创新微技术公司 | 循环肿瘤细胞有丝分裂指数在癌症分层和诊断中的应用 |
| MX2024007563A (es) | 2021-12-17 | 2024-08-27 | Bioaffinity Tech Inc | Detección de cáncer de pulmón en etapa temprana en esputo utilizando citometría de flujo automatizada y aprendizaje automático. |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
| DE19736691A1 (de) * | 1997-08-22 | 1999-02-25 | Michael Prof Dr Med Giesing | Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen |
| AU1585799A (en) * | 1997-11-14 | 1999-06-07 | General Hospital Corporation, The | Treatment of hematologic disorders |
| US20010018192A1 (en) * | 1998-02-12 | 2001-08-30 | Terstappen Leon W.M.M. | Labeled cells for use as an internal functional control in rare cell detection assays |
| BR9907852A (pt) * | 1998-02-12 | 2000-10-24 | Immunivest Corp | Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes |
| US7029652B2 (en) * | 1998-09-16 | 2006-04-18 | The Regents Of The University Of California | Method of treating tumors |
| US6551843B1 (en) * | 1999-01-29 | 2003-04-22 | Immunivest Corporation | Methods for enhancing binding interactions between members of specific binding pairs |
| US6222096B1 (en) * | 1999-03-01 | 2001-04-24 | Stine Biotechnology | Promoter and construct for plant transformation |
| US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| ATE488529T1 (de) * | 1999-07-28 | 2010-12-15 | Genentech Inc | Zusammensetzungen und verfahren zur behandlung von tumoren |
| CA2404431C (en) * | 2000-03-27 | 2011-06-07 | Thomas Jefferson University | Guanylyl cyclase c in the detection of stomach and esophageal cancers |
| CN1516597A (zh) * | 2000-10-13 | 2004-07-28 | Ī��ʲ��ѧ | 胸腺功能的诊断指示指标 |
| US7223596B2 (en) * | 2003-09-05 | 2007-05-29 | Wisconsin Alumni Research Foundation | Malignant endothelial cell line and uses thereof in models for angiogenesis |
| WO2006130737A1 (en) * | 2005-06-02 | 2006-12-07 | Immunivest Corporation | A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells |
| US20070037173A1 (en) * | 2005-08-12 | 2007-02-15 | Allard Jeffrey W | Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients |
-
2008
- 2008-10-20 EP EP08855440.7A patent/EP2225563B1/en active Active
- 2008-10-20 US US12/254,188 patent/US20090136946A1/en not_active Abandoned
- 2008-10-20 DK DK08855440.7T patent/DK2225563T3/en active
- 2008-10-20 CN CN200880118137.XA patent/CN101878429B/zh active Active
- 2008-10-20 BR BRPI0819854-3A patent/BRPI0819854B1/pt not_active IP Right Cessation
- 2008-10-20 WO PCT/US2008/080436 patent/WO2009070392A1/en not_active Ceased
- 2008-10-20 JP JP2010536033A patent/JP5479355B2/ja not_active Expired - Fee Related
- 2008-10-20 KR KR1020107013842A patent/KR101604649B1/ko active Active
- 2008-10-20 CA CA2706442A patent/CA2706442C/en active Active
- 2008-10-20 MX MX2010005811A patent/MX2010005811A/es active IP Right Grant
-
2010
- 2010-05-20 IL IL205864A patent/IL205864A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN101878429A (zh) | 2010-11-03 |
| DK2225563T3 (en) | 2015-02-09 |
| WO2009070392A1 (en) | 2009-06-04 |
| US20090136946A1 (en) | 2009-05-28 |
| CA2706442A1 (en) | 2009-06-04 |
| KR101604649B1 (ko) | 2016-03-18 |
| MX2010005811A (es) | 2010-06-09 |
| CN101878429B (zh) | 2015-05-20 |
| JP5479355B2 (ja) | 2014-04-23 |
| EP2225563A1 (en) | 2010-09-08 |
| HK1148348A1 (en) | 2011-09-02 |
| KR20100101109A (ko) | 2010-09-16 |
| IL205864A (en) | 2016-12-29 |
| JP2011505012A (ja) | 2011-02-17 |
| CA2706442C (en) | 2017-07-11 |
| EP2225563A4 (en) | 2011-11-16 |
| HK1148068A1 (en) | 2011-08-26 |
| IL205864A0 (en) | 2010-11-30 |
| BRPI0819854B1 (pt) | 2019-06-04 |
| EP2225563B1 (en) | 2015-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 11A ANUIDADE. |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2536 DE 13-08-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |