BRPI0820177A2 - Métodos para produzir um extrato de proteína a partir de células fixadas ou não-fixadas e para detectar uma proteína alvo, sistema para produzir um extrato de proteína, kit para produzir um extrato de proteína de células fixadas ou não-fixadas, e, método para extrair uma proteína viral alvo de uma amostra celular - Google Patents
Métodos para produzir um extrato de proteína a partir de células fixadas ou não-fixadas e para detectar uma proteína alvo, sistema para produzir um extrato de proteína, kit para produzir um extrato de proteína de células fixadas ou não-fixadas, e, método para extrair uma proteína viral alvo de uma amostra celularInfo
- Publication number
- BRPI0820177A2 BRPI0820177A2 BRPI0820177-3A2A BRPI0820177A BRPI0820177A2 BR PI0820177 A2 BRPI0820177 A2 BR PI0820177A2 BR PI0820177 A BRPI0820177 A BR PI0820177A BR PI0820177 A2 BRPI0820177 A2 BR PI0820177A2
- Authority
- BR
- Brazil
- Prior art keywords
- protein
- extract
- produce
- target
- detect
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title 3
- 102000004169 proteins and genes Human genes 0.000 title 3
- 108010067390 Viral Proteins Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4044—Concentrating samples by chemical techniques; Digestion; Chemical decomposition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/985547 | 2007-11-14 | ||
| US11/985,547 US9207240B2 (en) | 2007-11-14 | 2007-11-14 | Method of efficient extraction of protein from cells |
| PCT/US2008/083707 WO2009065091A1 (en) | 2007-11-14 | 2008-11-14 | Method of efficient extraction of protein from cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0820177A2 true BRPI0820177A2 (pt) | 2014-11-04 |
| BRPI0820177B1 BRPI0820177B1 (pt) | 2019-07-02 |
| BRPI0820177B8 BRPI0820177B8 (pt) | 2021-07-27 |
Family
ID=40624059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820177A BRPI0820177B8 (pt) | 2007-11-14 | 2008-11-14 | métodos para produzir um extrato de proteína a partir de células fixadas ou não-fixadas |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9207240B2 (pt) |
| EP (1) | EP2222838B1 (pt) |
| JP (1) | JP5787519B2 (pt) |
| CN (2) | CN107629109A (pt) |
| AU (1) | AU2008322473B2 (pt) |
| BR (1) | BRPI0820177B8 (pt) |
| CA (1) | CA2705765C (pt) |
| ES (1) | ES2456341T3 (pt) |
| WO (1) | WO2009065091A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101460636A (zh) | 2006-05-11 | 2009-06-17 | 伯克顿迪金森公司 | 从细胞中提取蛋白质的方法 |
| US8865162B2 (en) * | 2008-06-13 | 2014-10-21 | Oncohealth Corp. | Monoclonal antibodies against HPV proteins |
| US9207240B2 (en) | 2007-11-14 | 2015-12-08 | Arbor Vita Corporation | Method of efficient extraction of protein from cells |
| CN102575220B (zh) | 2009-09-03 | 2015-09-16 | 贝克顿·迪金森公司 | 用于直接化学裂解的方法和组合物 |
| US8658417B2 (en) * | 2009-09-15 | 2014-02-25 | Qiagen Gaithersburg, Inc. | Multiple-input analytical system |
| US8994937B2 (en) | 2012-04-18 | 2015-03-31 | Hewlett-Packard Development Company, L.P. | Surface enhanced Raman spectroscopy calibration curve generating systems |
| US9680916B2 (en) | 2013-08-01 | 2017-06-13 | Flowtraq, Inc. | Methods and systems for distribution and retrieval of network traffic records |
| JP6397224B2 (ja) * | 2014-06-04 | 2018-09-26 | 田中貴金属工業株式会社 | 免疫学的測定試薬におけるプロゾーン現象の解消法 |
| CN104237198A (zh) * | 2014-07-31 | 2014-12-24 | 中国人民解放军第二军医大学 | 一种判定中药材或中药饮片是否染色的方法 |
| ES3050636T3 (en) * | 2016-05-31 | 2025-12-22 | Hoffmann La Roche | Method for serological detection of viral antigens |
| CN107621462B (zh) * | 2016-07-13 | 2020-03-31 | 王志伟 | 一种组织透明化液sut及其制备和应用 |
| WO2018130072A1 (zh) * | 2017-01-12 | 2018-07-19 | 厦门大学 | 稳定呼吸道合胞病毒融合蛋白的方法 |
| JP2021506896A (ja) * | 2017-12-22 | 2021-02-22 | ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー | 生物学的サンプル、好ましくは加工植物種子ミールからの膜結合型タンパク質の単離のための方法および手段 |
| JP7267548B2 (ja) * | 2019-04-24 | 2023-05-02 | 株式会社ニップン | トマト黄化葉巻ウイルス(tylcv)の免疫学的診断法 |
| CN112213164A (zh) * | 2019-07-12 | 2021-01-12 | 温州医科大学附属第一医院 | 一种总蛋白提取试剂盒及提取方法 |
| CN116223793A (zh) * | 2023-02-14 | 2023-06-06 | 上海乐备实生物技术有限公司 | 一种用于外泌体中补体检测的裂解液及其应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3546334A (en) | 1965-05-21 | 1970-12-08 | Lerner Lab Inc | Composition for fixing and protecting a smear of body cells and method of applying same |
| US3303038A (en) | 1965-07-29 | 1967-02-07 | Ethicon Inc | Process of forming collagen articles and dispersions |
| JPS5535088B2 (pt) | 1971-09-10 | 1980-09-11 | ||
| US4578282A (en) | 1982-02-04 | 1986-03-25 | Harrison James S | Composition for diagnostic reagents |
| US4766065A (en) | 1984-08-23 | 1988-08-23 | Becton Dickinson And Company | Detection of cell membrane protein |
| US4649192A (en) * | 1985-05-30 | 1987-03-10 | Smith Kline-Rit | Method for the isolation and purification of hepatitis B surface antigen using polysorbate |
| US4857300A (en) | 1987-07-27 | 1989-08-15 | Cytocorp, Inc. | Cytological and histological fixative formulation and methods for using same |
| US5047325A (en) | 1988-10-07 | 1991-09-10 | Eastman Kodak Company | Wash solution containing a cationic surfactant and its use in chlamydial and gonococcal determinations |
| US5132205A (en) | 1988-10-07 | 1992-07-21 | Eastman Kodak Company | High ph extraction composition and its use to determine a chlamydial, gonococcal or herpes antigen |
| US5081010A (en) | 1989-02-09 | 1992-01-14 | Eastman Kodak Company | Extraction composition, test kit and their use to extract or determine herpes simplex viral antigen |
| US5104640A (en) | 1989-03-17 | 1992-04-14 | Wescor, Inc. | Fixative composition for fixing blood smears to slides |
| US5256571A (en) | 1991-05-01 | 1993-10-26 | Cytyc Corporation | Cell preservative solution |
| US5196182A (en) | 1991-05-08 | 1993-03-23 | Streck Laboratories, Inc. | Tissue fixative |
| US5773277A (en) * | 1992-06-26 | 1998-06-30 | Seikagaku Kogyo Kabushiki Kaisha | Crystalline chondroitinase isolated from Proteus vulgaris ATCC 6896 |
| US5432056A (en) | 1993-11-15 | 1995-07-11 | Ventana Medical Systems, Inc. | Bisulfite-based tissue fixative |
| US5658749A (en) | 1994-04-05 | 1997-08-19 | Corning Clinical Laboratories, Inc. | Method for processing mycobacteria |
| US5620869A (en) | 1995-09-28 | 1997-04-15 | Becton, Dickinson And Company | Methods for reducing inhibition of nucleic acid amplification reactions |
| US7306926B2 (en) | 1998-07-01 | 2007-12-11 | Mtm Laboratories Ag | Method for detecting carcinomas in a solubilized cervical body sample |
| US6245568B1 (en) * | 1999-03-26 | 2001-06-12 | Merck & Co., Inc. | Human papilloma virus vaccine with disassembled and reassembled virus-like particles |
| US20060148711A1 (en) | 1999-05-14 | 2006-07-06 | Arbor Vita Corporation | Molecular interactions in neurons |
| US20050037969A1 (en) | 1999-05-14 | 2005-02-17 | Arbor Vita Corporation | Molecular interactions in hematopoietic cells |
| US20050019841A1 (en) | 1999-05-14 | 2005-01-27 | Arbor Vita Corporation | Modulation of signaling pathways |
| US6488671B1 (en) | 1999-10-22 | 2002-12-03 | Corazon Technologies, Inc. | Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same |
| UA76708C2 (uk) * | 1999-12-08 | 2006-09-15 | Сінгента Патисипейшонс Аг | Антитіло, яке застосовується в імунологічному аналізі зразка для визначення неонікотиноїдного інсектициду, білковий кон'югат для одержання антитіла, спосіб визначення концентрації неонікотиноїдного інсектициду в зразку та набір для визначення кількості неонікотиноїдного інсектициду |
| US6337189B1 (en) | 2000-02-08 | 2002-01-08 | Streck Laboratories, Inc. | Fixative system, method and composition for biological testing |
| US6436662B1 (en) | 2000-04-04 | 2002-08-20 | Digene Corporation | Device and method for cytology slide preparation |
| WO2002007751A1 (en) | 2000-07-25 | 2002-01-31 | Axcell Biosciences Corporation | Identification and isolation of novel polypeptides having pdz domains and methods of using same |
| JP2004515752A (ja) * | 2000-09-15 | 2004-05-27 | バイオジェネックス ラボラトリーズ | insituハイブリダイゼーションの向上 |
| US7312041B2 (en) | 2001-02-16 | 2007-12-25 | Arbor Vita Corporation | Methods of diagnosing cervical cancer |
| KR100702373B1 (ko) | 2001-06-22 | 2007-04-02 | 에프. 호프만-라 로슈 아게 | 레트로바이러스 표면 당단백질을 함유하는 가용성 복합체 |
| AU2003270548B2 (en) | 2002-09-09 | 2008-09-25 | Arbor Vita Corporation | Methods of diagnosing cervical cancer |
| US20050032105A1 (en) | 2001-10-12 | 2005-02-10 | Bair Robert Jackson | Compositions and methods for using a solid support to purify DNA |
| EP1507148B1 (en) | 2003-08-25 | 2005-02-23 | MTM Laboratories AG | Method for detecting carcinomas in a solubilized cervical body sample |
| EP1558748A4 (en) | 2002-11-01 | 2008-10-22 | Promega Corp | CELL SYSE COMPOSITIONS, USE METHOD, DEVICE AND KIT |
| WO2005058933A1 (en) | 2003-12-16 | 2005-06-30 | Gentra Systems, Inc. | Formulations and methods for denaturing proteins |
| EP1708745B1 (en) | 2003-12-23 | 2012-04-18 | Arbor Vita Corporation | Antibodies for oncogenic strains of hpv and methods of their use |
| CA2562447A1 (en) * | 2004-04-15 | 2005-12-15 | Allied Biotech, Inc. | Methods and apparatus for detection of viral infection |
| AP2006003861A0 (en) * | 2004-06-09 | 2006-12-31 | Pathogen Removal And Diagnosti | Particles embedded in a porous substrate for removing target analyte from a sample |
| CN101460636A (zh) | 2006-05-11 | 2009-06-17 | 伯克顿迪金森公司 | 从细胞中提取蛋白质的方法 |
| US9207240B2 (en) | 2007-11-14 | 2015-12-08 | Arbor Vita Corporation | Method of efficient extraction of protein from cells |
-
2007
- 2007-11-14 US US11/985,547 patent/US9207240B2/en active Active
-
2008
- 2008-11-14 CA CA2705765A patent/CA2705765C/en not_active Expired - Fee Related
- 2008-11-14 CN CN201710593190.6A patent/CN107629109A/zh active Pending
- 2008-11-14 EP EP08850323.0A patent/EP2222838B1/en not_active Not-in-force
- 2008-11-14 BR BRPI0820177A patent/BRPI0820177B8/pt not_active IP Right Cessation
- 2008-11-14 AU AU2008322473A patent/AU2008322473B2/en not_active Ceased
- 2008-11-14 JP JP2010534253A patent/JP5787519B2/ja not_active Expired - Fee Related
- 2008-11-14 CN CN200880124680.0A patent/CN101910400B/zh not_active Expired - Fee Related
- 2008-11-14 ES ES08850323.0T patent/ES2456341T3/es active Active
- 2008-11-14 WO PCT/US2008/083707 patent/WO2009065091A1/en not_active Ceased
-
2015
- 2015-11-04 US US14/932,693 patent/US9995745B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2222838B1 (en) | 2014-01-22 |
| CN101910400B (zh) | 2017-06-27 |
| US9995745B2 (en) | 2018-06-12 |
| WO2009065091A1 (en) | 2009-05-22 |
| JP5787519B2 (ja) | 2015-09-30 |
| BRPI0820177B1 (pt) | 2019-07-02 |
| BRPI0820177B8 (pt) | 2021-07-27 |
| EP2222838A4 (en) | 2011-01-05 |
| CA2705765A1 (en) | 2009-05-22 |
| CN107629109A (zh) | 2018-01-26 |
| AU2008322473B2 (en) | 2014-07-03 |
| AU2008322473A1 (en) | 2009-05-22 |
| US20160216258A1 (en) | 2016-07-28 |
| US20090123910A1 (en) | 2009-05-14 |
| CA2705765C (en) | 2018-12-11 |
| US9207240B2 (en) | 2015-12-08 |
| EP2222838A1 (en) | 2010-09-01 |
| ES2456341T3 (es) | 2014-04-22 |
| JP2011503208A (ja) | 2011-01-27 |
| CN101910400A (zh) | 2010-12-08 |
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| Date | Code | Title | Description |
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