BRPI0820229A2 - conjugados de análogos de fumagilina biodegradáveis biocompatíveis - Google Patents
conjugados de análogos de fumagilina biodegradáveis biocompatíveisInfo
- Publication number
- BRPI0820229A2 BRPI0820229A2 BRPI0820229A BRPI0820229A BRPI0820229A2 BR PI0820229 A2 BRPI0820229 A2 BR PI0820229A2 BR PI0820229 A BRPI0820229 A BR PI0820229A BR PI0820229 A BRPI0820229 A BR PI0820229A BR PI0820229 A2 BRPI0820229 A2 BR PI0820229A2
- Authority
- BR
- Brazil
- Prior art keywords
- biocompatible biodegradable
- fumagillin analog
- analog conjugates
- fumagillin
- conjugates
- Prior art date
Links
- NGGMYCMLYOUNGM-CSDLUJIJSA-N fumagillin Chemical class C([C@H]([C@H]([C@@H]1[C@]2(C)[C@H](O2)CC=C(C)C)OC)OC(=O)\C=C\C=C\C=C\C=C\C(O)=O)C[C@@]21CO2 NGGMYCMLYOUNGM-CSDLUJIJSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyethers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US458207P | 2007-11-28 | 2007-11-28 | |
| PCT/US2008/084539 WO2009073445A2 (en) | 2007-11-28 | 2008-11-24 | Biocompatible biodegradable fumagillin analog conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0820229A2 true BRPI0820229A2 (pt) | 2017-05-09 |
Family
ID=40600044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820229A BRPI0820229A2 (pt) | 2007-11-28 | 2008-11-24 | conjugados de análogos de fumagilina biodegradáveis biocompatíveis |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8399512B2 (pt) |
| EP (1) | EP2217283A2 (pt) |
| JP (1) | JP5557746B2 (pt) |
| CN (1) | CN101990441A (pt) |
| AU (1) | AU2008331516B2 (pt) |
| BR (1) | BRPI0820229A2 (pt) |
| CA (1) | CA2706914A1 (pt) |
| EA (1) | EA020251B1 (pt) |
| IL (1) | IL206057A0 (pt) |
| MX (1) | MX2010005857A (pt) |
| NZ (2) | NZ600039A (pt) |
| WO (1) | WO2009073445A2 (pt) |
| ZA (1) | ZA201003819B (pt) |
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-
2008
- 2008-11-24 BR BRPI0820229A patent/BRPI0820229A2/pt not_active IP Right Cessation
- 2008-11-24 WO PCT/US2008/084539 patent/WO2009073445A2/en not_active Ceased
- 2008-11-24 EA EA201070657A patent/EA020251B1/ru not_active IP Right Cessation
- 2008-11-24 CN CN2008801221269A patent/CN101990441A/zh active Pending
- 2008-11-24 CA CA2706914A patent/CA2706914A1/en not_active Abandoned
- 2008-11-24 EP EP08857683A patent/EP2217283A2/en not_active Withdrawn
- 2008-11-24 NZ NZ600039A patent/NZ600039A/xx not_active IP Right Cessation
- 2008-11-24 JP JP2010536101A patent/JP5557746B2/ja not_active Expired - Fee Related
- 2008-11-24 NZ NZ585547A patent/NZ585547A/xx not_active IP Right Cessation
- 2008-11-24 US US12/276,856 patent/US8399512B2/en not_active Expired - Fee Related
- 2008-11-24 MX MX2010005857A patent/MX2010005857A/es active IP Right Grant
- 2008-11-24 AU AU2008331516A patent/AU2008331516B2/en not_active Ceased
-
2010
- 2010-05-27 IL IL206057A patent/IL206057A0/en unknown
- 2010-05-27 ZA ZA2010/03819A patent/ZA201003819B/en unknown
-
2013
- 2013-02-15 US US13/769,024 patent/US20130158046A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009073445A3 (en) | 2010-01-28 |
| NZ600039A (en) | 2013-11-29 |
| US20130158046A1 (en) | 2013-06-20 |
| US8399512B2 (en) | 2013-03-19 |
| CN101990441A (zh) | 2011-03-23 |
| JP2011504964A (ja) | 2011-02-17 |
| US20090148396A1 (en) | 2009-06-11 |
| NZ585547A (en) | 2012-12-21 |
| WO2009073445A2 (en) | 2009-06-11 |
| CA2706914A1 (en) | 2009-06-11 |
| EA201070657A1 (ru) | 2010-12-30 |
| JP5557746B2 (ja) | 2014-07-23 |
| MX2010005857A (es) | 2010-11-22 |
| IL206057A0 (en) | 2010-11-30 |
| EA020251B1 (ru) | 2014-09-30 |
| ZA201003819B (en) | 2013-09-25 |
| EP2217283A2 (en) | 2010-08-18 |
| AU2008331516A1 (en) | 2009-06-11 |
| AU2008331516B2 (en) | 2014-01-09 |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
| B25B | Requested transfer of rights rejected |
Owner name: MERSANA THERAPEUTICS, INC. (US) , CHERI A. STEVENS |
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| B15K | Others concerning applications: alteration of classification |
Ipc: C07D 303/40 (2006.01), A61K 47/59 (2017.01), C07D |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] |