BRPI0821458A2 - Derivado 6-heterocíclico-imidazo[1,2-a]pirroína-2-carboxamida s, o respectivo preparo e a respectiva aplicação em, terapêutica - Google Patents

Derivado 6-heterocíclico-imidazo[1,2-a]pirroína-2-carboxamida s, o respectivo preparo e a respectiva aplicação em, terapêutica

Info

Publication number: BRPI0821458A2
Authority: BR; Brazil
Prior art keywords: pyrroin; imidazo; carboxamide; therapeutics; heterocyclic
Prior art date: 2008-01-02

Application number

BRPI0821458-1A

Other languages

English (en)

Inventor

Jean-François Peyronel

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-02

Filing date

2008-12-31

Publication date

2015-06-16

2008-12-31 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2015-06-16 Publication of BRPI0821458A2 publication Critical patent/BRPI0821458A2/pt

Links

239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Cardiology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0821458-1A 2008-01-02 2008-12-31 Derivado 6-heterocíclico-imidazo[1,2-a]pirroína-2-carboxamida s, o respectivo preparo e a respectiva aplicação em, terapêutica BRPI0821458A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0800005A FR2925903B1 (fr)	2008-01-02	2008-01-02	DERIVES 6-HETEROCYCLIQUE-IMIDAZO°1,2-a!PYRIDINE-2- CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
PCT/FR2008/001836 WO2009106750A2 (fr)	2008-01-02	2008-12-31	Dérivés 6-heterocyclique-imidazo[1,2-a]pyrroine-2-carboxamides, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number	Publication Date
BRPI0821458A2 true BRPI0821458A2 (pt)	2015-06-16

Family

ID=39745373

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0821458-1A BRPI0821458A2 (pt)	2008-01-02	2008-12-31	Derivado 6-heterocíclico-imidazo[1,2-a]pirroína-2-carboxamida s, o respectivo preparo e a respectiva aplicação em, terapêutica

Country Status (24)

Country	Link
US (2)	US8314109B2 (pt)
EP (1)	EP2225240B1 (pt)
JP (1)	JP5258899B2 (pt)
KR (1)	KR101600635B1 (pt)
CN (1)	CN101959884B (pt)
AR (1)	AR070074A1 (pt)
AU (1)	AU2008351928B2 (pt)
BR (1)	BRPI0821458A2 (pt)
CA (1)	CA2710947C (pt)
CL (1)	CL2008003928A1 (pt)
CO (1)	CO6331309A2 (pt)
EA (1)	EA019122B1 (pt)
FR (1)	FR2925903B1 (pt)
IL (1)	IL206669A (pt)
MA (1)	MA32527B1 (pt)
ME (1)	ME01157B (pt)
MX (1)	MX2010007353A (pt)
MY (1)	MY155468A (pt)
NZ (1)	NZ586474A (pt)
SG (1)	SG187408A1 (pt)
TW (1)	TWI432432B (pt)
UY (1)	UY31589A1 (pt)
WO (1)	WO2009106750A2 (pt)
ZA (1)	ZA201004644B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2925907B1 (fr) *	2008-01-02	2010-10-15	Sanofi Aventis	DERIVES DE 2-HETEROAROYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
CA2852615A1 (en) *	2011-10-21	2013-04-25	Torrent Pharmaceuticals Limited	Novel substituted imidazopyrimidines as gpbar1 receptor modulators
US9573881B2 (en)	2012-12-25	2017-02-21	Nippon Soda Co., Ltd.	Halogenated aniline and method for producing same
CN108295074B (zh) *	2018-02-01	2020-08-28	华中农业大学	一种噻二唑并三嗪类化合物在制备单胺氧化酶抑制剂中的用途
KR102819183B1 (ko)	2019-03-29	2025-06-13	한미약품 주식회사	퓨로피리미딘 화합물의 산 부가염의 결정형

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2638161B1 (fr) *	1988-10-24	1991-01-11	Centre Nat Rech Scient	Nouvelles benzoyl-2 imidazo (1,2-a) pyridines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
IE904346A1 (en) *	1989-12-04	1991-06-05	Searle & Co	IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
EP1597355A2 (en) *	2002-09-24	2005-11-23	Neuro Therapeutics AB	Method and materials relating to neurogenesis
US7405299B2 (en) *	2002-11-27	2008-07-29	Eli Lilly And Company	Compounds as pharmaceutical agents
WO2004103991A1 (en) *	2003-05-20	2004-12-02	'chemical Diversity Research Institute', Ltd.	2-substituted piperidines, focused library and a pharmaceutical compound
DE102005019181A1 (de) *	2005-04-25	2006-10-26	Novartis Ag	Peptid-Deformylase (PDF) Inhibitoren 1
FR2903106B1 (fr) *	2006-07-03	2010-07-30	Sanofi Aventis	Utilisations de 2-benzoyl-imidazopyridines en therapeutique
FR2903108B1 (fr) *	2006-07-03	2008-08-29	Sanofi Aventis Sa	Utilisation de derives d'imidazo[1,2-a] pyridine-2-carboxamides en therapeutique.
FR2903107B1 (fr) *	2006-07-03	2008-08-22	Sanofi Aventis Sa	Derives d'imidazopyridine-2-carboxamides, leur preparation et leur application en therapeutique

2008
- 2008-01-02 FR FR0800005A patent/FR2925903B1/fr not_active Expired - Fee Related
- 2008-12-30 UY UY31589A patent/UY31589A1/es not_active Application Discontinuation
- 2008-12-30 AR ARP080105779A patent/AR070074A1/es unknown
- 2008-12-30 CL CL2008003928A patent/CL2008003928A1/es unknown
- 2008-12-31 NZ NZ586474A patent/NZ586474A/en not_active IP Right Cessation
- 2008-12-31 EA EA201070814A patent/EA019122B1/ru not_active IP Right Cessation
- 2008-12-31 MX MX2010007353A patent/MX2010007353A/es active IP Right Grant
- 2008-12-31 WO PCT/FR2008/001836 patent/WO2009106750A2/fr not_active Ceased
- 2008-12-31 KR KR1020107017143A patent/KR101600635B1/ko not_active Expired - Fee Related
- 2008-12-31 CA CA2710947A patent/CA2710947C/fr not_active Expired - Fee Related
- 2008-12-31 MY MYPI2010003073A patent/MY155468A/en unknown
- 2008-12-31 AU AU2008351928A patent/AU2008351928B2/en not_active Ceased
- 2008-12-31 EP EP08872775.5A patent/EP2225240B1/fr active Active
- 2008-12-31 ME MEP-2010-103A patent/ME01157B/me unknown
- 2008-12-31 BR BRPI0821458-1A patent/BRPI0821458A2/pt not_active IP Right Cessation
- 2008-12-31 TW TW097151708A patent/TWI432432B/zh not_active IP Right Cessation
- 2008-12-31 CN CN2008801277669A patent/CN101959884B/zh not_active Expired - Fee Related
- 2008-12-31 SG SG2012096269A patent/SG187408A1/en unknown
- 2008-12-31 JP JP2010541085A patent/JP5258899B2/ja not_active Expired - Fee Related
2010
- 2010-06-28 IL IL206669A patent/IL206669A/en not_active IP Right Cessation
- 2010-07-01 US US12/828,374 patent/US8314109B2/en not_active Expired - Fee Related
- 2010-07-01 ZA ZA2010/04644A patent/ZA201004644B/en unknown
- 2010-07-02 CO CO10080887A patent/CO6331309A2/es active IP Right Grant
- 2010-07-27 MA MA33051A patent/MA32527B1/fr unknown
2012
- 2012-10-10 US US13/648,731 patent/US8691990B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN101959884A (zh)	2011-01-26
KR20100109940A (ko)	2010-10-11
AR070074A1 (es)	2010-03-10
MY155468A (en)	2015-10-15
WO2009106750A2 (fr)	2009-09-03
ME01157B (me)	2013-03-20
WO2009106750A3 (fr)	2010-02-25
TW200934780A (en)	2009-08-16
UY31589A1 (es)	2009-08-03
SG187408A1 (en)	2013-02-28
US8691990B2 (en)	2014-04-08
CA2710947A1 (fr)	2009-09-03
EP2225240B1 (fr)	2014-01-22
JP5258899B2 (ja)	2013-08-07
FR2925903A1 (fr)	2009-07-03
CL2008003928A1 (es)	2010-02-12
FR2925903B1 (fr)	2011-01-21
US20130041152A1 (en)	2013-02-14
CO6331309A2 (es)	2011-10-20
AU2008351928A1 (en)	2009-09-03
JP2011508760A (ja)	2011-03-17
MA32527B1 (fr)	2011-08-01
CA2710947C (fr)	2016-04-12
IL206669A (en)	2015-07-30
MX2010007353A (es)	2010-08-18
CN101959884B (zh)	2013-02-27
TWI432432B (zh)	2014-04-01
EA201070814A1 (ru)	2011-02-28
EA019122B1 (ru)	2014-01-30
HK1148016A1 (en)	2011-08-26
US20100317675A1 (en)	2010-12-16
US8314109B2 (en)	2012-11-20
EP2225240A2 (fr)	2010-09-08
ZA201004644B (en)	2011-11-30
NZ586474A (en)	2012-06-29
AU2008351928B2 (en)	2013-11-21
KR101600635B1 (ko)	2016-03-07
IL206669A0 (en)	2010-12-30

Legal Events

Date	Code	Title	Description
2015-11-24	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2016-03-15	B08G	Application fees: restoration [chapter 8.7 patent gazette]
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-10-30	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 10A ANUIDADE.
2019-02-12	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-03-19	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2495 DE 30-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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