BRPI0822540A2 - Preparação e uso de um extrato de planta de solanum glaucophyllum com um teor enriquecido de d3 glicosídeos de 1,25-di-hidroxivitamina e glicosídeos de quercetina - Google Patents

Preparação e uso de um extrato de planta de solanum glaucophyllum com um teor enriquecido de d3 glicosídeos de 1,25-di-hidroxivitamina e glicosídeos de quercetina

Info

Publication number: BRPI0822540A2
Authority: BR; Brazil
Prior art keywords: glycosides; dihydroxyvitamin; preparation; plant extract; quercetin
Prior art date: 2008-04-21

Application number

BRPI0822540-0A

Other languages

English (en)

Inventor

Sabrina Autzen

Heinrich Bachmann

Original Assignee

Herbonis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-04-21

Filing date

2008-04-21

Publication date

2015-06-23

2008-04-21 Application filed by Herbonis Ag filed Critical Herbonis Ag

2015-06-23 Publication of BRPI0822540A2 publication Critical patent/BRPI0822540A2/pt

2023-05-16 Publication of BRPI0822540B1 publication Critical patent/BRPI0822540B1/pt

Links

-1 1,25-dihydroxyvitamin d3 glycosides Chemical class 0.000 title 2
229930182470 glycoside Natural products 0.000 title 2
GMRQFYUYWCNGIN-UHFFFAOYSA-N 1,25-Dihydroxy-vitamin D3' Natural products C1CCC2(C)C(C(CCCC(C)(C)O)C)CCC2C1=CC=C1CC(O)CC(O)C1=C GMRQFYUYWCNGIN-UHFFFAOYSA-N 0.000 title 1
ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 title 1
HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 title 1
235000005004 Solanum glaucophyllum Nutrition 0.000 title 1
241000511905 Solanum glaucophyllum Species 0.000 title 1
229960005084 calcitriol Drugs 0.000 title 1
MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 title 1
239000000419 plant extract Substances 0.000 title 1
229960001285 quercetin Drugs 0.000 title 1
REFJWTPEDVJJIY-UHFFFAOYSA-N quercetin Natural products C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 title 1
235000005875 quercetin Nutrition 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Natural Medicines & Medicinal Plants (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Mycology (AREA)
Biotechnology (AREA)
Botany (AREA)
Medical Informatics (AREA)
Microbiology (AREA)
Alternative & Traditional Medicine (AREA)
Epidemiology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)

BRPI0822540-0A 2008-04-21 2008-04-21 Método para a preparação e purificação de um extrato de planta enriquecido de solanum glaucophyllum tendo um teor enriquecido de glicosídeos de 1,25-di-hidroxivitamina d3 e glicosídeos de quercetina BRPI0822540B1 (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2008/003191 WO2009129818A1 (en)	2008-04-21	2008-04-21	Preparation and use of a plant extract from solanum glaucophyllum with an enriched content of 1,25-dihydroxyvitamin d3 glycosides and quercetin glycosides

Publications (2)

Publication Number	Publication Date
BRPI0822540A2 true BRPI0822540A2 (pt)	2015-06-23
BRPI0822540B1 BRPI0822540B1 (pt)	2023-05-16

Family

ID=39735396

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0822540-0A BRPI0822540B1 (pt)	2008-04-21	2008-04-21	Método para a preparação e purificação de um extrato de planta enriquecido de solanum glaucophyllum tendo um teor enriquecido de glicosídeos de 1,25-di-hidroxivitamina d3 e glicosídeos de quercetina

Country Status (11)

Country	Link
US (2)	US8465781B2 (pt)
EP (1)	EP2265277B1 (pt)
JP (1)	JP5390594B2 (pt)
CN (1)	CN102014945B (pt)
AU (1)	AU2008355402B2 (pt)
BR (1)	BRPI0822540B1 (pt)
CA (1)	CA2721566C (pt)
DK (1)	DK2265277T3 (pt)
ES (1)	ES2702987T3 (pt)
PL (1)	PL2265277T3 (pt)
WO (2)	WO2009129818A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5243875B2 (ja) *	2008-07-31	2013-07-24	日本配合飼料株式会社	反芻動物用飼料
DK2440213T3 (da) *	2009-06-10	2014-01-20	Emma Nutrition	Anvendelse af 1,25-dihydroxyvitamin D3-glycosid i lakterende dyr
BE1019408A5 (nl) *	2009-06-10	2012-07-03	Emma Nutrition	Gebruik van 1,25-dihydroxyvitamine d3 glycoside bij melkgevende dieren.
AU2010309784B2 (en)	2009-10-20	2016-11-10	Herbonis Ag	Composition comprising Solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing blood calcium levels
JP2013508338A (ja) *	2009-10-20	2013-03-07	ヘルボニスアクチェンゲゼルシャフト	骨代謝障害および腎障害の治療を目的としたＳａｌｏｎｕｍＧｌａｕｃｏｐｈｙｌｌｕｍ由来エキスの使用
WO2012019644A1 (en) *	2010-08-11	2012-02-16	Herbonis Ag	Producing 1alpha, 25 -dihydroxyvitamin d3 in plant cells and plants and methods for up-regulating corresponding metabolic pathways
US9327006B2 (en)	2011-08-04	2016-05-03	Ramaswamy Rajendran	Extraction of B-vitamins from plant matter
WO2013018105A2 (en) *	2011-08-04	2013-02-07	Ramaswamy Rajendran	Extraction of vitamins and minerals from plant matter
GB2550100B (en) *	2013-04-23	2020-06-03	Herbonis Ag	Method for improving mineral resorption in farmed fish and crustacean
EP2990789A4 (en) *	2013-04-26	2016-05-04	Sumitomo Electric Industries	METHOD FOR SEARCHING FOR ORGANIC SUBSTANCES IN A SOLUTION TO BE INVESTIGATED
FR3005419B1 (fr)	2013-05-13	2015-09-04	Agronomique Inst Nat Rech	Utilisation d'une association de deux composes pour le traitement et/ou la prevention de troubles osseux
CN104710485B (zh) *	2015-01-13	2017-06-27	南京理工大学	维生素d2糖苷类似物、合成及应用
US20180133278A1 (en) *	2015-04-24	2018-05-17	Victor ATAMANIUK	Plant-based biologically active substance having a polypharmacological effect
DE102016105369A1 (de) *	2016-03-22	2017-09-28	Bernd Büter	Erzeugnis, insbesondere Nahrungsmittelzusatz, Futtermittel oder Tierfutterzusatz und Verfahren zu dessen Herstellung
CN111084780A (zh) *	2020-01-09	2020-05-01	昆明医科大学	老鹳草素在制备治疗骨质疏松合并骨折的药物中的用途
WO2022029037A1 (en) *	2020-08-06	2022-02-10	Herbonis Ag	Method for preventing myopathies in poultry and compositions useful therefor
US20230248761A1 (en) *	2022-02-10	2023-08-10	Contract Manufacturing Services, LLC	Method for supporting normal blood calcium concentrations in mammals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4521410A (en)	1984-05-03	1985-06-04	The General Hospital Corporation	Vitamin D glycosyl orthoesters
DE69331833T2 (de)	1992-12-29	2002-11-14	Michael F. Holick	Verwendung von vitamin d-glykosiden zur behandlung oder prävention von osteoporose
AT398372B (de)	1993-06-04	1994-11-25	Binder Erich	Verfahren zur prophylaxe der hypokalzämischen gebärlähmung und der atypischen gebärparese des rindes
US5776461A (en) *	1996-07-26	1998-07-07	Chesebrough-Pond's Usa Co., Division Of Conopco, Inc.	Cosmetic compositions containing phytovitamin D
JP4041843B2 (ja) *	2004-07-15	2008-02-06	島根県	クエルセチン３−ｏ−（６−ｏ−マロニル）グルコシドを有効成分として含む医薬組成物およびクエルセチンマロニルグルコシドを含有する食品

2008
- 2008-04-21 CN CN200880128743XA patent/CN102014945B/zh active Active
- 2008-04-21 WO PCT/EP2008/003191 patent/WO2009129818A1/en not_active Ceased
- 2008-04-21 ES ES08735341T patent/ES2702987T3/es active Active
- 2008-04-21 CA CA2721566A patent/CA2721566C/en active Active
- 2008-04-21 AU AU2008355402A patent/AU2008355402B2/en active Active
- 2008-04-21 DK DK08735341.3T patent/DK2265277T3/en active
- 2008-04-21 PL PL08735341T patent/PL2265277T3/pl unknown
- 2008-04-21 BR BRPI0822540-0A patent/BRPI0822540B1/pt active IP Right Grant
- 2008-04-21 JP JP2011505365A patent/JP5390594B2/ja active Active
- 2008-04-21 US US12/988,598 patent/US8465781B2/en active Active
- 2008-04-21 EP EP08735341.3A patent/EP2265277B1/en active Active
2009
- 2009-04-21 WO PCT/EP2009/002906 patent/WO2009130005A2/en not_active Ceased
2013
- 2013-06-17 US US13/919,560 patent/US9446088B2/en active Active

Also Published As

Publication number	Publication date
CN102014945A (zh)	2011-04-13
CN102014945B (zh)	2013-05-15
WO2009129818A1 (en)	2009-10-29
DK2265277T3 (en)	2019-01-21
PL2265277T3 (pl)	2019-06-28
EP2265277A1 (en)	2010-12-29
ES2702987T3 (es)	2019-03-06
EP2265277B1 (en)	2018-10-03
AU2008355402B2 (en)	2014-04-17
US20130280351A1 (en)	2013-10-24
CA2721566C (en)	2016-04-05
JP5390594B2 (ja)	2014-01-15
US20110038960A1 (en)	2011-02-17
JP2011518201A (ja)	2011-06-23
US8465781B2 (en)	2013-06-18
WO2009130005A3 (en)	2010-01-21
WO2009130005A2 (en)	2009-10-29
AU2008355402A1 (en)	2009-10-29
CA2721566A1 (en)	2009-10-29
US9446088B2 (en)	2016-09-20
BRPI0822540B1 (pt)	2023-05-16

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Legal Events

Date	Code	Title	Description
2017-02-21	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2017-05-16	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2017-10-31	B07G	Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
2018-05-02	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2018-08-28	B09B	Patent application refused [chapter 9.2 patent gazette]
2018-11-06	B12B	Appeal against refusal [chapter 12.2 patent gazette]
2023-05-16	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/04/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.
2023-06-20	B25G	Requested change of headquarter approved	Owner name: HERBONIS AG (CH)