BRPI0900780A2 - makeup and dermatologically insect repellent bar - Google Patents
makeup and dermatologically insect repellent bar Download PDFInfo
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- BRPI0900780A2 BRPI0900780A2 BRPI0900780-6A BRPI0900780A BRPI0900780A2 BR PI0900780 A2 BRPI0900780 A2 BR PI0900780A2 BR PI0900780 A BRPI0900780 A BR PI0900780A BR PI0900780 A2 BRPI0900780 A2 BR PI0900780A2
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- insect repellent
- base
- glycerin
- repellent
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- 239000000077 insect repellent Substances 0.000 title claims abstract description 18
- 239000000203 mixture Substances 0.000 claims abstract description 46
- 239000005871 repellent Substances 0.000 claims abstract description 25
- 230000002940 repellent Effects 0.000 claims abstract description 25
- 239000000344 soap Substances 0.000 claims abstract description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 17
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 14
- 229940110456 cocoa butter Drugs 0.000 claims description 11
- 235000019868 cocoa butter Nutrition 0.000 claims description 11
- 238000009472 formulation Methods 0.000 claims description 11
- GJWSUKYXUMVMGX-UHFFFAOYSA-N citronellic acid Chemical compound OC(=O)CC(C)CCC=C(C)C GJWSUKYXUMVMGX-UHFFFAOYSA-N 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 235000011187 glycerol Nutrition 0.000 claims description 9
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 8
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 8
- 239000002480 mineral oil Substances 0.000 claims description 8
- 235000010446 mineral oil Nutrition 0.000 claims description 8
- 239000012188 paraffin wax Substances 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 8
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims description 8
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 claims description 8
- 235000012141 vanillin Nutrition 0.000 claims description 8
- SMVRDGHCVNAOIN-UHFFFAOYSA-L disodium;1-dodecoxydodecane;sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC SMVRDGHCVNAOIN-UHFFFAOYSA-L 0.000 claims description 7
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims description 7
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 claims description 7
- 229960003415 propylparaben Drugs 0.000 claims description 7
- 229940057910 shea butter Drugs 0.000 claims description 7
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 6
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 6
- 229930006000 Sucrose Natural products 0.000 claims description 6
- 239000005720 sucrose Substances 0.000 claims description 6
- 229930008398 Citronellate Natural products 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 claims description 4
- QLHULAHOXSSASE-UHFFFAOYSA-N butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate Chemical compound CCC(C)OC(=O)N1CCCCC1CCO QLHULAHOXSSASE-UHFFFAOYSA-N 0.000 claims description 4
- 229960001673 diethyltoluamide Drugs 0.000 claims description 4
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims description 4
- ZHYZQXUYZJNEHD-VQHVLOKHSA-N geranic acid Chemical compound CC(C)=CCC\C(C)=C\C(O)=O ZHYZQXUYZJNEHD-VQHVLOKHSA-N 0.000 claims description 4
- 229930008392 geranic acid Natural products 0.000 claims description 4
- ZHYZQXUYZJNEHD-UHFFFAOYSA-N trans-geranic acid Natural products CC(C)=CCCC(C)=CC(O)=O ZHYZQXUYZJNEHD-UHFFFAOYSA-N 0.000 claims description 4
- OJISWRZIEWCUBN-QIRCYJPOSA-N (E,E,E)-geranylgeraniol Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO OJISWRZIEWCUBN-QIRCYJPOSA-N 0.000 claims description 3
- XWRJRXQNOHXIOX-UHFFFAOYSA-N geranylgeraniol Natural products CC(C)=CCCC(C)=CCOCC=C(C)CCC=C(C)C XWRJRXQNOHXIOX-UHFFFAOYSA-N 0.000 claims description 3
- OJISWRZIEWCUBN-UHFFFAOYSA-N geranylnerol Natural products CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCO OJISWRZIEWCUBN-UHFFFAOYSA-N 0.000 claims description 3
- LMXFTMYMHGYJEI-UHFFFAOYSA-N p-menthane-3,8-diol Chemical compound CC1CCC(C(C)(C)O)C(O)C1 LMXFTMYMHGYJEI-UHFFFAOYSA-N 0.000 claims description 3
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims description 2
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 claims description 2
- 239000005770 Eugenol Substances 0.000 claims description 2
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims description 2
- 229940043350 citral Drugs 0.000 claims description 2
- 229960002217 eugenol Drugs 0.000 claims description 2
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 claims description 2
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 229930006948 p-menthane-3,8-diol Natural products 0.000 claims description 2
- 238000009827 uniform distribution Methods 0.000 claims description 2
- 244000166675 Cymbopogon nardus Species 0.000 claims 1
- 235000018791 Cymbopogon nardus Nutrition 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 235000014121 butter Nutrition 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 abstract description 5
- 241000282414 Homo sapiens Species 0.000 abstract description 4
- 241001465754 Metazoa Species 0.000 abstract description 3
- 210000003491 skin Anatomy 0.000 description 7
- 206010012310 Dengue fever Diseases 0.000 description 6
- 208000001490 Dengue Diseases 0.000 description 5
- 208000025729 dengue disease Diseases 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 241000255925 Diptera Species 0.000 description 3
- 229940042472 mineral oil Drugs 0.000 description 3
- 229940056211 paraffin Drugs 0.000 description 3
- -1 stick Substances 0.000 description 3
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 241000288906 Primates Species 0.000 description 2
- 206010058874 Viraemia Diseases 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 241000238876 Acari Species 0.000 description 1
- 206010001935 American trypanosomiasis Diseases 0.000 description 1
- 208000024699 Chagas disease Diseases 0.000 description 1
- 241000710781 Flaviviridae Species 0.000 description 1
- 241000710831 Flavivirus Species 0.000 description 1
- 208000032456 Hemorrhagic Shock Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 208000009714 Severe Dengue Diseases 0.000 description 1
- 206010049771 Shock haemorrhagic Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 241000223109 Trypanosoma cruzi Species 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 201000002950 dengue hemorrhagic fever Diseases 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
COMPOSIÇçO E BARRA DERMATOLàGICA REPELENTE DE INSETOS. A presente patente de invenção refere-se a um modelo de sabonete repelente a seco, também denominado no campo farmacêutico de barra, com ação repelente a insetos, para uso humano e animal.COMPOSITION AND DERMATOLOGICALLY INSECT BAR. The present invention relates to a model of dry repellent soap, also known in the pharmaceutical field as insect repellent bar for human and animal use.
Description
COMPOSIÇÃO E BARRA DERMATOLÓGICA REPELENTE OE INSETOS"COMPOSITION AND DERMATOLOGICAL BAR REPELLENT AND INSECTS "
A presente patente de invenção refere-se a um modelo desabonete repelente a seco, também denominado no campo farmacêutico debarra, com ação repelente a insetos, para uso humano e animal.The present invention relates to a dry repellent soap model, also known in the pharmaceutical field as insect repellent, for human and animal use.
Doenças transmitidas por insetos são responsáveis poraproximadamente 700 milhões de casos/ano no mundo, dentre as quaispodemos citar a malária, a Ieishmaniose1 a doença de Chagas, a febre do sonoe a dengue. No Brasil, a dengue é a manifestação de maior incidência causadapor insetos.Insect-borne diseases are responsible for approximately 700 million cases per year worldwide, among which we can mention malaria, Ieishmaniasis1, Chagas disease, sleep fever and dengue fever. In Brazil, dengue is the manifestation of higher incidence caused by insects.
Denomina-se dengue a enfermidade causada por arbovírusda família Flaviviridae, gênero flavivirus, que inclui quatro tipos imunológicos:1,2,3 e 4.Dengue is the disease caused by arbovirus of the family Flaviviridae, genus flavivirus, which includes four immunological types: 1,2,3 and 4.
A dengue tem como hospedeiro vertebrado o Homem eoutros primatas, mas somente o primeiro apresenta manifestação clínica daínfecção e período de viremía de aproximadamente sete dias. Nos demaisprimatas, a viremia é baixa e de curta duração.Dengue has as vertebrate host man and other primates, but only the first presents clinical manifestation of infection and viremia period of approximately seven days. In other primates, viremia is low and short-lived.
Atualmente, a dengue é a arbovirose mais comum queatinge o homem, sendo responsável por cerca de 100 milhões de casos/anoem populações de risco de 2,5 a 3 bilhões de seres humanos no mundo inteiro.A febre hemorrágica da dengue e a síndrome de choque atingem pelo menos500 mil pessos/ano no mundo apresentando taxa de mortalidade de até 10 %para pacientes hospitalizados e 30 % para pacientes não tratados no mundo.Dengue is currently the most common arbovirus affecting men, accounting for about 100 million cases / year in at-risk populations of 2.5 to 3 billion human beings worldwide. Dengue hemorrhagic fever and shock reach at least 500,000 people / year worldwide with a mortality rate of up to 10% for hospitalized patients and 30% for untreated patients worldwide.
No mercado, são conhecidas diferentes formulações derepelentes comerciais em líquido, loção, gel, bastão, espuma, spray, aerossol ecreme, com concentrações e eficácias variadas, onde as matérias primasnaturais e sintéticas estão presentes isoladas e/ou associadas, o que confereuma característica específica a cada produto.Different commercially available formulations of liquid, lotion, gel, stick, foam, spray, aerosol ecreme are known in the market, with varying concentrations and efficiencies, where natural and synthetic raw materials are present alone and / or associated, which confers a specific characteristic. to each product.
Em que se pese a utilização desses produtos, algunsinconvenientes podem ser atribuídos, como por exemplo, a aplicação deformulações em spray/aerossol próximo aos olhos e mucosas édesaconselhado devido a imtabilidade proporcionada pelos componentes dafórmula.Despite the use of these products, some drawbacks may be attributed, for example, the application of spray / aerosol deformities near the eyes and mucous membranes is discouraged due to the immutability provided by the components of the formula.
Outro problema dos repelentes, relativo à formafarmacêutica creme e gel, é a demasiada utilização do produto numa mesmaaplicação, podendo ocasionar superdosagem.Another problem of repellents, concerning the cream and gel pharmaceutical form, is the overuse of the product in the same application and may cause overdose.
Tendo em vista esses problemas e no propósito de superá-los, fia desenvolvida uma composição sob a forma de uma barra que contémingredientes específicos para repetir insetos, preferiveimente mosquitos ecarrapatos, prevenindo e protegendo de suas picadas/mordidas.In view of these problems and for the purpose of overcoming them, a bar-shaped composition has been developed that contains specific insect repeating ingredients, preferably mosquitoes and ticks, preventing and protecting from their bites / bites.
A barra dermatológica repelente, objeto da presente patente,consiste em aplicar sobre a pele uma formulação em forma de barra, como umsabonete seco de pH neutro ou fisiológico, sem a utilização de água, a fim degerar uma película espessa e uniforme sobre a pele, com a vantagem deminimizar a aplicação excessiva, evitar o desperdício na aplicação e a perdapara o ambiente, resultando em maior tempo de durabilidade do produto, e,conseqüentemente, em menor custo para o usuário.The repellent dermatological bar, object of the present invention, is to apply a bar-shaped formulation to the skin as a neutral or physiological pH dry soap without the use of water in order to generate a thick and uniform skin film, With the advantage of minimizing over-application, avoiding application wastage and waste to the environment, resulting in longer product durability and therefore lower cost to the user.
A composição da barra dermatológica repelente éconstituída de uma base glicerinada de sabonete de pH levemente alcalino, deIauni éter sulfato de sódio, etanol, giicenna, sacarose, propilenoglicol, EDTA,corantes, água, manteiga de cacau, parafina, manteiga de Karíté, óleo mineral,proptlparabeno, BHT1 vanilina, ácido gerânico e ácido citronêlico.The composition of the repellent dermatological bar consists of a glycerinated base of mildly alkaline pH soap, sodium launi ether sulfate, ethanol, giicenna, sucrose, propylene glycol, EDTA, dyes, water, cocoa butter, paraffin, shea butter, mineral oil. proptlparaben, BHT1 vanillin, geranic acid and citronellic acid.
A formulação apresentada acima constitui a base glicerinadadas demais variações apresentadas abaixo, onde somente a substância ativa évariável, o que confere características diversas ao produto final, como tempode eficiência, facilidade de distribuição sob a forma de um filme (pequenapelícula) na derme sem a necessidade de adição de água, pois contémhidratantes e emolientes que proporcionam umidade e maciez à pele.The formulation presented above constitutes the base glycerinated other variations presented below, where only the active substance is variable, which confers diverse characteristics to the final product, such as efficiency, ease of distribution in the form of a film (small film) in the dermis without the need addition of water, as it contains moisturizers and emollients that provide moisture and softness to the skin.
Também constitui objeto da presente invenção a inclusão damanteiga de cacau na formulação, pois esta é responsável pela distribuiçãouniforme do produto sobre a pele, não permitindo a geração de espuma, deforma que a barra dermatológica forme um filme sobre a pele/pêlo.It is also an object of the present invention to include cocoa butter in the formulation, as it is responsible for the uniform distribution of the product on the skin, not allowing the generation of foam, so that the skin bar forms a film on the skin / hair.
As substâncias repelentes ativas usadas na inserção dabase glicerinada são: DEET (N.N-díetil meta-toluamída), citral, cítroneía,geranilgeraniol, ácido citronêlico, ácido geranílico, eugenol, p-mentano-3,8-diole picaridina (Icaridina);The active repellent substances used in the glycerinated dabase insertion are: DEET (N.N-dimethyl meta-toluamide), citral, citrone, geranylgeraniol, citronellic acid, geranylic acid, eugenol, p-menthane-3,8-diole picaridine (Icaridine);
O fixador dos óleos essenciais utilizados é a vanilina.The fixative of the essential oils used is vanillin.
A barra dermatológica repelente possui pH que varia doneutro (pH = 7,0) ao fisiológico (faixa entre pH =4,6 a 5,8) em sabonetes demassa vegetal.The repellent dermatological bar has a pH ranging from doneutro (pH = 7.0) to physiological (range between pH = 4.6 to 5.8) in excess vegetable soaps.
A presente invenção tem como objetivo duas formulações debase glicerinada que constituem a composição da barra dermatológicarepelente, variando somente as substâncias repelentes ativas de composiçãovariável.The present invention aims at two glycerin based formulations which constitute the composition of the dermatological bar and the composition, varying only the active repellent substances of variable composition.
As seguintes proporções são utilizadas na formulação de100g da base glicerinada para a composição da barra dermatológica repelente:The following proportions are used in the 100g formulation of the glycerinated base for the repellent dermatological bar composition:
Composição 1:0a 65% de glicerina; 5% de Iauril éter sulfato de sódio; 3 a 6%de água; 1 a 5% de etanol; 2 a 5% de sacarose; 1 a 3% de propilenoglicol; 0,5a 1 % EDTA; 2 a 5% de manteiga de cacau; 2 a 6% de manteiga de Karité; 0,5a 3% de óleo mineral; 0,5 a 2 % de parafina; 0,1 a 0,3 % de BHT; 0,3 a 0,6 %de propilparabeno e 3% de vanilina.Composition 1: 0 to 65% glycerin; 5% sodium lauryl ether sulfate; 3 to 6% water; 1 to 5% ethanol; 2 to 5% sucrose; 1 to 3% propylene glycol; 0.5 to 1% EDTA; 2 to 5% cocoa butter; 2 to 6% shea butter; 0.5 to 3% mineral oil; 0.5 to 2% paraffin; 0.1 to 0.3% BHT; 0.3 to 0.6% propylparaben and 3% vanillin.
Composição 2: 0 a 65% de glicerina; 5% de Iauril éter sulfato de sódio; 3 a 6%de água; 1 a 5% de etanol; 2 a 5% de sacarose; 1 a 3% de propilenoglicol; 1 a0,5 % EDTA; 2 a 5% de manteiga de cacau; 2 a 6% de manteiga de Karité; 0,5a 3% de óleo mineral; 0,5 a 2 % de parafina; 0,1 a 0,3 % de BHT; 0,3 a 0,6 %de propilparabeno; 3% de vanilina; 3 a 6% de ácido gerânico; 3 a 6% de ácidocitronêlico.Composition 2: 0 to 65% glycerin; 5% sodium lauryl ether sulfate; 3 to 6% water; 1 to 5% ethanol; 2 to 5% sucrose; 1 to 3% propylene glycol; 1 to 0.5% EDTA; 2 to 5% cocoa butter; 2 to 6% shea butter; 0.5 to 3% mineral oil; 0.5 to 2% paraffin; 0.1 to 0.3% BHT; 0.3 to 0.6% propylparaben; 3% vanillin; 3 to 6% geranic acid; 3 to 6% of cititronellic acid.
As substâncias repelentes ativas utilizadas separadamentena formulação da composição 1 são: o DEET ( Ν,Ν-dietil mata-toluamida) naconcentração de 15 a 30%, com tempo de ação repelente que varia de 6 a 8horas, e Picaridina (Icaridina) na concentração de 10 a 20%, com tempo deação repelente que varia de 8 a 10 horas.The active repellent substances used separately in the formulation of composition 1 are: DEET (Ν, Ν-diethyl mata-toluamide) at a concentration of 15 to 30%, with repellent action time ranging from 6 to 8 hours, and Picaridine (Icaridine) in concentration 10 to 20%, with repellent donation time ranging from 8 to 10 hours.
Na composição 2, as substâncias ativas utilizadasseparadamente na composição são: p-mentano-3,8-diol na concentração quevaria de 25 a 30%, com tempo de ação repelente que varia de 6 a 8 horas, e ogeranilgeranio! na concentração de 15 a 20%, com tempo de ação repelenteque varia de 6 a 8 horas.In composition 2, the active substances used separately in the composition are: p-menthane-3,8-diol at a concentration of 25 to 30%, with repellent action time ranging from 6 to 8 hours, and ogeranylgeranium! at a concentration of 15 to 20%, with repellent action time ranging from 6 to 8 hours.
Os componentes da formulação se apresentam em baseaquosa no estado líquido e sólido, em temperatura ambiente normal, e sãosolúveis entre si, de forma a facilitar o processo de fabricação.The formulation components are liquid and solid based at normal room temperature and are soluble in order to facilitate the manufacturing process.
O processo de fabricação consiste em adicionar osreagentes em um Becker adaptado com um termômetro, para aquecimento a40°C, na seguinte ordem e concentrações acima especificados para acomposição 1: glicerína, Iauril éter sulfato de sódio, água, etanol, saca rose,propilenoglicoí, EDTA1 manteiga de cacau, manteiga de karité, óleo mineral,parafina, BHT, propilparabeno, vanilina, e, para a composição 2: glicerína,Iauril éter sulfato de sódio, água, etanol, sacarose, propilenoglicoí, EDTAmanteiga de cacau, manteiga de karité, óleo mineral, parafina, BHT,propilparabeno, vanilina, ácido gerânico e ácido átronêlico, que são misturadose homogeneizados com agitação mecânica.The manufacturing process consists of adding the reagents to a Becker fitted with a thermometer for heating to 40 ° C in the following order and concentrations specified above for composition 1: glycerin, lauryl ether sodium sulfate, water, ethanol, rose sac, propylene glycol, EDTA1 cocoa butter, shea butter, mineral oil, paraffin, BHT, propylparaben, vanillin, and for composition 2: glycerin, lauryl ether sodium sulfate, water, ethanol, sucrose, propylene glycol, EDTA cocoa butter, shea butter , mineral oil, paraffin, BHT, propylparaben, vanillin, geranic acid and atronic acid, which are mixed and homogenized with mechanical agitation.
A presente patente apresenta as seguintes propriedades:uma barra dermatológica repelente não irritante, de composição compatívelquando combinada com altas concentrações de repelentes naturais e produtosquímicos, e concentração suficientemente comprovada de repelentes químicospara fornecer máxima proteção intrínseca, bem como prolongar a sua açãorepelente.The present patent has the following properties: a non-irritating repellent dermatological bar of compatible composition when combined with high concentrations of natural repellents and chemicals, and sufficiently proven concentration of chemical repellents to provide maximum intrinsic protection as well as prolong its repellent action.
A invenção descrita acima fornece, também, um métodopara a proteção de animais contra a picada/mordida de insetos, que inclui aaplicação na pele/pêlo de um montante eficaz da composição da barradermatolóagica repelente.The invention described above also provides a method for protecting animals against insect bite / bite, which includes applying to the skin / hair an effective amount of the repellent barradermatological composition.
A composição, de acordo com a invenção, afeta os insetos,em particular os mosquitos, através do uso de repelentes tópicos queinterferem com os sensores do mosquito fêmea, desviando-a de seu ataquecaminho.The composition according to the invention affects insects, particularly mosquitoes, through the use of topical repellents that interfere with the female mosquito's sensors, diverting it from its attack.
Outros ingredientes, como perfumes e corantes, sãoopcionais por não serem prejudiciais fisiologicamente.Other ingredients, such as perfumes and dyes, are optional as they are not physiologically harmful.
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0900780A BRPI0900780B1 (en) | 2009-03-20 | 2009-03-20 | insect repellent dermatological composition and bar |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0900780A BRPI0900780B1 (en) | 2009-03-20 | 2009-03-20 | insect repellent dermatological composition and bar |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0900780A2 true BRPI0900780A2 (en) | 2010-12-14 |
| BRPI0900780B1 BRPI0900780B1 (en) | 2018-10-30 |
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ID=43332423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0900780A BRPI0900780B1 (en) | 2009-03-20 | 2009-03-20 | insect repellent dermatological composition and bar |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BRPI0900780B1 (en) |
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2009
- 2009-03-20 BR BRPI0900780A patent/BRPI0900780B1/en not_active IP Right Cessation
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| Publication number | Publication date |
|---|---|
| BRPI0900780B1 (en) | 2018-10-30 |
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