BRPI0905725B8 - vacina e embalagem farmacêutica - Google Patents

vacina e embalagem farmacêutica

Info

Publication number
BRPI0905725B8
BRPI0905725B8 BRPI0905725A BRPI0905725A BRPI0905725B8 BR PI0905725 B8 BRPI0905725 B8 BR PI0905725B8 BR PI0905725 A BRPI0905725 A BR PI0905725A BR PI0905725 A BRPI0905725 A BR PI0905725A BR PI0905725 B8 BRPI0905725 B8 BR PI0905725B8
Authority
BR
Brazil
Prior art keywords
vaccine
individual
administered
polypeptide
pharmaceutical packaging
Prior art date
Application number
BRPI0905725A
Other languages
English (en)
Inventor
B Plikaytis Bonnie
Cheruvu Mani
Roa Amara Rama
Sable Suraj
M Shinnick Thomas
Original Assignee
Univ Emory
The Government Of The Us Secretary Department Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Emory, The Government Of The Us Secretary Department Of Health And Human Services filed Critical Univ Emory
Publication of BRPI0905725A2 publication Critical patent/BRPI0905725A2/pt
Publication of BRPI0905725B1 publication Critical patent/BRPI0905725B1/pt
Publication of BRPI0905725B8 publication Critical patent/BRPI0905725B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

vacina, embalagem farmacêutica e processo para criar uma resposta imune em tecido celular de indivíduo. é fornecida uma vacina em que um poiipeptídeo ou combinação de peptídeos de m. tuberculosis é administrada a um indivíduo para suscitar uma resposta imune. a vacina polipeptídica é administrada como parte de uma estratégia de dose inicial-reforço (prime-boost) com a vacina bcg para aumentar a imunoproteção em um indivíduo tal que a prevenção ou eliminação da doença seja alcançada. finalmente, é provida uma embalagem farmacêutica que abrange uma vacina polipeptídica para m- tuberculosis que, quando administrada a um indivíduo suscita imunoproteção.
BRPI0905725A 2008-01-11 2009-01-12 vacina e embalagem farmacêutica BRPI0905725B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2057308P 2008-01-11 2008-01-11
US61/020,573 2008-01-11
PCT/US2009/030754 WO2009089535A2 (en) 2008-01-11 2009-01-12 Polypeptide vaccine and vaccination strategy against mycobacterium

Publications (3)

Publication Number Publication Date
BRPI0905725A2 BRPI0905725A2 (pt) 2015-12-01
BRPI0905725B1 BRPI0905725B1 (pt) 2020-12-29
BRPI0905725B8 true BRPI0905725B8 (pt) 2021-05-25

Family

ID=40853787

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0905725A BRPI0905725B8 (pt) 2008-01-11 2009-01-12 vacina e embalagem farmacêutica

Country Status (6)

Country Link
US (1) US8741313B2 (pt)
EP (2) EP2818178A1 (pt)
CN (1) CN101969976A (pt)
BR (1) BRPI0905725B8 (pt)
WO (1) WO2009089535A2 (pt)
ZA (1) ZA201005742B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9597379B1 (en) 2010-02-09 2017-03-21 David Gordon Bermudes Protease inhibitor combination with therapeutic proteins including antibodies
US8771669B1 (en) 2010-02-09 2014-07-08 David Gordon Bermudes Immunization and/or treatment of parasites and infectious agents by live bacteria
US8524220B1 (en) 2010-02-09 2013-09-03 David Gordon Bermudes Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria
CN101850111B (zh) * 2010-04-07 2013-07-31 四川大学 一种用于结核病预防的新型疫苗
CN101822829B (zh) * 2010-04-07 2013-07-31 四川大学 一种用于结核病预防的重组卡介苗
PL2661253T3 (pl) * 2011-01-04 2017-08-31 Archivel Farma, Sl Preparat liposomowy odpowiedni do leczenia lub zapobiegania gruźlicy
EP2471511A1 (en) * 2011-01-04 2012-07-04 Archivel Farma, SL Liposome formulation suitable for treating or preventing tuberculosis
DK2802345T3 (en) 2012-01-12 2018-04-30 Archivel Farma Sl MTB-C-VACCINE AGAINST ALLERGIC REACTIONS
BR102012003790A2 (pt) * 2012-02-17 2014-04-22 Fundacao Butantan Cepa de mycobacterium recombinante, composição imunogênica e uso
RU2539026C1 (ru) * 2013-06-11 2015-01-10 Федеральное государственное бюджетное учреждение "Центральный научно-исследовательский институт туберкулеза" Российской академии медицинских наук РЕКОМБИНАНТНАЯ ПЛАЗМИДА pESAT6-CFP10-DBD, РЕКОМБИНАНТНЫЙ ШТАММ Escherichia coli M15 [pREP4, pESAT6-CFP10-DBD], СПОСОБ ПОЛУЧЕНИЯ, ИММОБИЛИЗАЦИИ, КОНЦЕНТРИРОВАНИЯ И ОЧИСТКИ РЕКОМБИНАНТНОГО БЕЛКА ESAT6-CFP10-DBD НА ДЕКСТРАНЕ, РЕКОМБИНАНТНЫЙ БЕЛОК ESAT6-CFP10-DBD И ИММУНОГЕННАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ БЕЛОК ESAT6-CFP10-DBD
US10370437B2 (en) 2013-08-30 2019-08-06 Longhorn Vaccines And Diagnostics, Llc Antibodies that modulate immunity to drug resistant and latent MTB infections
US10414819B2 (en) 2013-08-30 2019-09-17 Longhorn Vaccines And Diagnostics, Llc Monoclonal antibodies that modulate immunity to MTB and enhance immune clearance
AU2014312135B2 (en) * 2013-08-30 2017-09-07 Longhorn Vaccines And Diagnostics, Llc Enhancing immunity to tuberculosis
US9737592B1 (en) 2014-02-14 2017-08-22 David Gordon Bermudes Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
BR112019004913B1 (pt) * 2016-09-16 2022-07-12 Infectious Disease Research Institute Vacinas que compreendem polipeptídeos de mycobacterium leprae para a prevenção, tratamento e diagnóstico de lepra
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2018236876A2 (en) * 2017-06-19 2018-12-27 Washington University Nanoemulsion and methods of use thereof
EP3743103A4 (en) * 2018-01-26 2021-03-17 The Regents of The University of California INTRANASAL ADMINISTRATION OF CYCLIC DI-NUCLEOTIDE ADJUVED VACCINE FOR TUBERCULOSIS
CN112770771A (zh) * 2018-09-17 2021-05-07 丘拉提斯股份有限公司 包含干扰素基因刺激蛋白激动剂的免疫佐剂及疫苗组合物
KR102317403B1 (ko) * 2019-01-28 2021-10-29 주식회사 바이오앱 당화된 Ag85A 단백질을 포함하는 결핵 예방용 백신 조성물 및 이의 제조방법
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
CN110240637A (zh) * 2019-06-04 2019-09-17 华中农业大学 牛分枝杆菌免疫相关的分子伴侣蛋白GroEL2及其编码基因与应用
CN110354098B (zh) * 2019-07-23 2021-01-05 中国农业大学 重组蛋白cfp-10纳米颗粒的制备及应用
US12285437B2 (en) 2019-10-30 2025-04-29 The Research Foundation For The State University Of New York Reversing the undesirable pH-profile of doxorubicin via activation of a disubstituted maleamic acid prodrug at tumor acidity
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
EP4217066A4 (en) * 2020-09-23 2024-10-23 The General Hospital Corporation BCG VACCINES TO PREVENT COVID-19 AND OTHER INFECTIOUS DISEASES
CN114404582B (zh) * 2021-12-20 2023-08-11 南京鼓楼医院 通过分枝杆菌特异性免疫治疗肿瘤的方法及使用的抗原肽

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196191A (en) 1975-09-29 1980-04-01 Burroughs Wellcome Co. Biological preparations
GB9525083D0 (en) 1995-12-07 1996-02-07 Danbiosyst Uk Vaccine compositions
US6096291A (en) 1996-12-27 2000-08-01 Biovector Therapeutics, S.A. Mucosal administration of substances to mammals
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
DE69912441T2 (de) 1998-08-19 2004-08-19 Skyepharma Canada Inc., Verdun Injizierbare wässerige propofoldispersionen
US6630169B1 (en) 1999-03-31 2003-10-07 Nektar Therapeutics Particulate delivery systems and methods of use
US6558670B1 (en) 1999-04-19 2003-05-06 Smithkline Beechman Biologicals S.A. Vaccine adjuvants
WO2001080831A2 (en) 2000-04-27 2001-11-01 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
US6368602B1 (en) 2000-06-16 2002-04-09 Hadasit Medical Research Services And Development Ltd Mucosal immunization against hepatitis A virus (HAV) through rectal administration of HAV vaccine
WO2002004018A2 (en) * 2000-07-10 2002-01-17 Colorado State University Research Foundation Mid-life vaccine and methods for boosting anti-mycobacterial immunity
US6541030B2 (en) 2000-09-27 2003-04-01 Verion Inc. Instant water dissolvable encapsulate and process
US6663861B2 (en) 2000-11-09 2003-12-16 Antibodyshop A/S Method of producing antibodies by immunization with conjugates of molecules coupled to charge-modified proteins
FR2818647B1 (fr) * 2000-12-21 2006-09-29 Pasteur Institut Glycopeptides immunogenes, criblage, preparation et applications
AU2002243630A1 (en) 2001-01-23 2002-08-06 Massachusetts Institute Of Technology Solid- and solution -phase synthesis of heparin and other glycosaminoglycans
US20040121322A9 (en) 2001-02-22 2004-06-24 Cole Stewart T. Comparative mycobacterial genomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
US7745141B2 (en) * 2001-06-21 2010-06-29 New York University Mycobacterial proteins as early antigens for serodiagnosis and vaccines
CN1694725A (zh) * 2001-08-02 2005-11-09 纽约大学 肽在早期检测分枝杆菌疾病中的应用
US20040009937A1 (en) 2002-01-31 2004-01-15 Wei Chen Methods and composition for delivering nucleic acids and/or proteins to the respiratory system
US20050075298A1 (en) 2002-01-31 2005-04-07 Wei Chen Methods and composition for delivering nucleic acids and/or proteins to the intestinal mucosa
WO2004006952A2 (en) * 2002-07-13 2004-01-22 Statens Serum Institut Therapeutic tuberculosis vaccines
WO2004094469A1 (en) 2003-04-23 2004-11-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Tuberculosis vaccine with improved efficacy
GB0323965D0 (en) 2003-10-13 2003-11-19 Glaxosmithkline Biolog Sa Immunogenic compositions
WO2005061534A2 (en) * 2003-12-23 2005-07-07 Statens Serum Institut Improved tuberculosis vaccines
EP1649869A1 (en) 2004-10-21 2006-04-26 Vakzine Projekt Management GmbH Combination of a recombinant mycobacterium and a biologically active agent as a vaccine
KR100609813B1 (ko) 2005-02-24 2006-08-08 학교법인연세대학교 결핵 예방 백신
BRPI0612833A2 (pt) * 2005-06-23 2010-11-30 Statens Seruminstitut composição imunogênica, vacina, composição farmacêutica, polipeptìdeo de fusão e uso das três primeiras

Also Published As

Publication number Publication date
CN101969976A (zh) 2011-02-09
EP2244720A2 (en) 2010-11-03
BRPI0905725A2 (pt) 2015-12-01
WO2009089535A2 (en) 2009-07-16
ZA201005742B (en) 2011-04-28
WO2009089535A3 (en) 2009-10-01
US8741313B2 (en) 2014-06-03
US20110027349A1 (en) 2011-02-03
EP2244720A4 (en) 2013-01-16
EP2818178A1 (en) 2014-12-31
BRPI0905725B1 (pt) 2020-12-29

Similar Documents

Publication Publication Date Title
BRPI0905725B8 (pt) vacina e embalagem farmacêutica
WO2010037395A3 (en) Mhc multimers in cancer vaccines and immune monitoring
PE20141906A1 (es) Esketamina para el tratamiento de la depresion refractaria al tratamiento o resistente al tratamiento
WO2012027379A3 (en) Interleukin-13 receptor alpha 2 peptide-based brain cancer vaccines
BR112012020839A2 (pt) vacinas para uso na profilaxe e tratamento de doença de vírus da influenza
BR212016030926U2 (pt) conjugados de alvo e partículas e formulações dos mesmos
BR112016016290A2 (pt) Composições farmacêuticas de insulina de ação rápida, conjunto de infusão, sistema de conjunto de infusão e usos de análogos monoméricos ou diméricos de insulina
CO6501124A2 (es) Polipeptidos inmunomoduladores derivados se la il 2 y su uso terapeutico en cancer y en infecciones crónicas
AU2009326524A8 (en) Use of Flt3 ligand for strengthening immune responses in RNA immunization
AR078247A1 (es) Vacuna de pcsk9
BR112012032008A2 (pt) anticorpos s100a4 e usos terapêuticos do mesmo
BR112013032410A2 (pt) composições farmacêuticas compreendendo uma combinação de veículos, vitaminas, taninos e flavonoides de seleção como imunomoduladores específicos de antígeno
MX347101B (es) Forma de dosis de disolucion rapida de vacuna oral que usa almidon.
CA2915027A1 (en) Compositions and methods for administration of vaccines against dengue virus
CL2007002825A1 (es) Metodo para generar vacunas que estimulen el sistema inmune que comprende inducir celulas mononucleares de sangre periferica a que se diferencien a apc, para luego, separar dichas apc y mezclarlas con adyuvantes; extracto de celulas tumorales; y comp
BR112013029417A2 (pt) composições de vacina de matriz proteica incluindo policátions
CY1124512T1 (el) Εμβολια καρκινου που στοχευουν καρκινικα βλαστοκυτταρα
BR112012016783A2 (pt) "usos do composto de naltrexona ou sal farmaceuticamente aceitável da mesma a bupropiona ou sal farmaceuticamente aceitável da mesma ou de composição dos mesmos e métodos para proporcionar terapia"
CR20150266A (es) Formulaciones de liberación modificada para oprozomib
EP4233896A3 (en) Method for preparing an immunogenic lysate, the lysate obtained, dendritic cells loaded with such lysate and a pharmaceutical composition comprising the lysate or the dendritic cells
MX368864B (es) Composicion para prevenir infeccion por mycoplasma spp.
PH12015502844B1 (en) Mammalian milk osteopontin for enhancing immune responsiveness
WO2010045431A3 (en) Dry powder formulations, vaccines and methods
WO2012078051A3 (en) IPN Vaccine
BR112014020184A8 (pt) Preparação farmacêutica que contém anlodipina e ra-mipril

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/12/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/01/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF