BRPI0907542A2 - Método para produzir ácido 5'-guanílico, e, microrganismo com uma capacidade de converter ácido inosínico em ácido 5'-guanílico - Google Patents
Método para produzir ácido 5'-guanílico, e, microrganismo com uma capacidade de converter ácido inosínico em ácido 5'-guanílicoInfo
- Publication number
- BRPI0907542A2 BRPI0907542A2 BRPI0907542-9A BRPI0907542A BRPI0907542A2 BR PI0907542 A2 BRPI0907542 A2 BR PI0907542A2 BR PI0907542 A BRPI0907542 A BR PI0907542A BR PI0907542 A2 BRPI0907542 A2 BR PI0907542A2
- Authority
- BR
- Brazil
- Prior art keywords
- acid
- guanylic
- microorganism
- convert
- ability
- Prior art date
Links
- RQFCJASXJCIDSX-UHFFFAOYSA-N 14C-Guanosin-5'-monophosphat Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(COP(O)(O)=O)C(O)C1O RQFCJASXJCIDSX-UHFFFAOYSA-N 0.000 title 2
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 title 2
- 235000013928 guanylic acid Nutrition 0.000 title 2
- AUHDWARTFSKSAC-HEIFUQTGSA-N (2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-(6-oxo-1H-purin-9-yl)oxolane-2-carboxylic acid Chemical compound [C@]1([C@H](O)[C@H](O)[C@@H](CO)O1)(N1C=NC=2C(O)=NC=NC12)C(=O)O AUHDWARTFSKSAC-HEIFUQTGSA-N 0.000 title 1
- GRSZFWQUAKGDAV-UHFFFAOYSA-N Inosinic acid Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-UHFFFAOYSA-N 0.000 title 1
- 235000013902 inosinic acid Nutrition 0.000 title 1
- 239000004245 inosinic acid Substances 0.000 title 1
- 229940028843 inosinic acid Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008043136 | 2008-02-25 | ||
| PCT/JP2009/053358 WO2009107631A1 (ja) | 2008-02-25 | 2009-02-25 | ５’－グアニル酸の製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0907542A2 true BRPI0907542A2 (pt) | 2015-07-28 |
Family
ID=41016021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0907542-9A BRPI0907542A2 (pt) | 2008-02-25 | 2009-02-25 | Método para produzir ácido 5'-guanílico, e, microrganismo com uma capacidade de converter ácido inosínico em ácido 5'-guanílico |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8309329B2 (pt) |
| EP (1) | EP2264144A4 (pt) |
| JP (1) | JP5440489B2 (pt) |
| KR (1) | KR101599977B1 (pt) |
| CN (1) | CN101960005B (pt) |
| BR (1) | BRPI0907542A2 (pt) |
| WO (1) | WO2009107631A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5636648B2 (ja) * | 2009-08-10 | 2014-12-10 | 味の素株式会社 | ５’−グアニル酸の製造法 |
| PH12013500068A1 (en) * | 2010-07-12 | 2016-11-16 | Inbiose Nv | Metabolically engineered organisms for the production of added value bio-products |
| CN104371939B (zh) * | 2013-08-15 | 2017-07-21 | 中国中化股份有限公司 | 一种培养处理焦化废水所用复合菌的培养基及其应用 |
| KR101599800B1 (ko) | 2014-03-21 | 2016-03-04 | 씨제이제일제당 주식회사 | Ｌ-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법 |
| US11544214B2 (en) * | 2015-02-02 | 2023-01-03 | Optimum Semiconductor Technologies, Inc. | Monolithic vector processor configured to operate on variable length vectors using a vector length register |
| CN110117568B (zh) * | 2018-02-06 | 2021-03-30 | 中国科学院微生物研究所 | 生产l-组氨酸的重组菌、其构建方法以及l-组氨酸的生产方法 |
| KR101956510B1 (ko) * | 2018-07-27 | 2019-03-08 | 씨제이제일제당 (주) | 신규 5'-이노신산 디하이드로게나아제 및 이를 이용한 5'-이노신산 제조방법 |
| KR102284843B1 (ko) | 2019-10-08 | 2021-08-02 | 씨제이제일제당 주식회사 | 5'-구아닐산이나트륨 7수화물 결정의 제조 방법 |
| WO2021239702A1 (en) * | 2020-05-25 | 2021-12-02 | Danmarks Tekniske Universitet | Permeabilized microbial cell catalysts |
| CN115678864B (zh) * | 2021-07-28 | 2025-08-29 | 梅花(上海)生物科技有限公司 | 产核苷的基因工程菌及其构建方法与应用 |
| KR102419166B1 (ko) * | 2021-09-23 | 2022-07-08 | 씨제이제일제당 주식회사 | 신규한 글루타민 가수분해 gmp 합성효소 변이체 및 이를 이용한 퓨린 뉴클레오티드의 생산방법 |
| EP4180523B1 (en) * | 2021-09-23 | 2024-08-21 | CJ Cheiljedang Corporation | Novel glutamine hydrolysis gmp synthase variant and method for producing purine nucleotides using same |
| TW202530412A (zh) * | 2024-01-22 | 2025-08-01 | 南韓商Ｃｊ第一製糖股份有限公司 | 新穎麩醯胺水解ｇｍｐ合成酶變體以及使用其生產５′—單磷酸鳥苷之方法 |
| WO2025165579A1 (en) * | 2024-02-01 | 2025-08-07 | International Flavors & Fragrances, Inc. | Process for producing products with amino acid and taste retention |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5612438A (en) | 1979-07-13 | 1981-02-06 | Mitsubishi Heavy Ind Ltd | Drag suction-head for sludge dredging |
| DE185092T1 (de) | 1984-03-12 | 1986-11-27 | Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo | Verfahren zur herstellung von 5'-guanylsaeure. |
| JPH0716431B2 (ja) | 1986-06-02 | 1995-03-01 | 協和醗酵工業株式会社 | ５′−グアニル酸の製造法 |
| JPS63233798A (ja) * | 1986-10-09 | 1988-09-29 | Kyowa Hakko Kogyo Co Ltd | ５′−グアニル酸の製造法 |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| JP2602927B2 (ja) | 1988-11-15 | 1997-04-23 | 協和醗酵工業株式会社 | アデノシン−５’−三リン酸の製造法 |
| JPH0328196A (ja) | 1989-06-27 | 1991-02-06 | Kawasaki Steel Corp | ダイヤモンドの気相合成方法 |
| JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
| KR970005914B1 (ko) | 1991-07-31 | 1997-04-22 | 제일제당 주식회사 | 유전자 재조합 미생물에 의한 5'-구아닐산의 제조방법 |
| JP3651036B2 (ja) | 1993-12-27 | 2005-05-25 | 味の素株式会社 | ヌクレオシド−５’−燐酸エステルの製造法 |
| PL184520B1 (pl) | 1995-03-24 | 2002-11-29 | Ajinomoto Kk | Sposób wytwarzania kwasu inozynowego lub guanylowego stransformowany mikroorganizm zrekombinowany DNA białko oraz gen |
| JP3941390B2 (ja) | 1995-05-25 | 2007-07-04 | 味の素株式会社 | 変異型酸性フォスファターゼ |
| JPH0937785A (ja) | 1995-05-25 | 1997-02-10 | Ajinomoto Co Inc | ヌクレオシド−５’−燐酸エステルの製造法 |
| JP4304727B2 (ja) | 1996-11-21 | 2009-07-29 | 味の素株式会社 | ヌクレオシド−５’−燐酸エステルの製造法 |
| US7435560B1 (en) * | 1997-07-18 | 2008-10-14 | Ajinomoto Co., Inc. | Method for producing purine nucleoside by fermentation |
| JP2007105056A (ja) * | 1997-07-18 | 2007-04-26 | Ajinomoto Co Inc | 発酵法によるプリンヌクレオシドの製造法 |
| JP2000135097A (ja) * | 1998-10-29 | 2000-05-16 | Ajinomoto Co Inc | 酵素法によるグアノシン５’−モノリン酸の製造法 |
| JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
| JP4696404B2 (ja) | 2000-07-05 | 2011-06-08 | 味の素株式会社 | 発酵法によるヌクレオチドの製造法 |
| EP1170370B1 (en) * | 2000-07-05 | 2006-09-27 | Ajinomoto Co., Inc. | Method for producing nucleotide by fermentation |
| JP2003325182A (ja) | 2002-05-10 | 2003-11-18 | Ajinomoto Co Inc | 発酵法によるヌクレオシド−５’−リン酸エステルの製造法 |
| DE102004001674B4 (de) | 2003-01-29 | 2019-01-24 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Lysin unter Einsatz von Methanol verwertenden Bakterien |
| PL1651758T3 (pl) | 2003-07-29 | 2009-04-30 | Ajinomoto Kk | Sposób wytwarzania L-lizyny lub L-treoniny przy użyciu bakterii Escherichia o atenuowanej aktywności enzymu jabłczanowego |
| US7183106B1 (en) * | 2004-05-28 | 2007-02-27 | The United States Of America As Represented By The United States Department Of Energy | Bacterial inosine 5′-monophosphate dehydrogenase (“IMPDH”) DNA as a dominant selectable marker in mammals and other eukaryotes |
| EP1838726A1 (en) | 2005-01-18 | 2007-10-03 | Ajinomoto Co., Inc. | L-amino acid producing microorganism and a method for producing l-amino acid |
| US7326546B2 (en) | 2005-03-10 | 2008-02-05 | Ajinomoto Co., Inc. | Purine-derived substance-producing bacterium and a method for producing purine-derived substance |
| KR101005707B1 (ko) * | 2005-12-14 | 2011-01-05 | 씨제이제일제당 (주) | 암모니아 특이적 5'-크산틸산 아미나아제 변이체 |
| CN101432418B (zh) | 2006-04-24 | 2012-11-14 | 味之素株式会社 | 能够产生嘌呤物质的细菌和用于产生嘌呤物质的方法 |
| JP5104754B2 (ja) | 2006-04-24 | 2012-12-19 | 味の素株式会社 | プリン系物質生産菌及びプリン系物質の製造法 |
-
2009
- 2009-02-25 EP EP09715319A patent/EP2264144A4/en not_active Withdrawn
- 2009-02-25 KR KR1020107020612A patent/KR101599977B1/ko not_active Expired - Fee Related
- 2009-02-25 CN CN200980106422.4A patent/CN101960005B/zh not_active Expired - Fee Related
- 2009-02-25 JP JP2010500701A patent/JP5440489B2/ja not_active Expired - Fee Related
- 2009-02-25 BR BRPI0907542-9A patent/BRPI0907542A2/pt not_active Application Discontinuation
- 2009-02-25 WO PCT/JP2009/053358 patent/WO2009107631A1/ja not_active Ceased
-
2010
- 2010-08-24 US US12/861,939 patent/US8309329B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2264144A4 (en) | 2012-11-07 |
| JP5440489B2 (ja) | 2014-03-12 |
| US20110045543A1 (en) | 2011-02-24 |
| CN101960005B (zh) | 2016-02-24 |
| EP2264144A1 (en) | 2010-12-22 |
| JPWO2009107631A1 (ja) | 2011-06-30 |
| WO2009107631A1 (ja) | 2009-09-03 |
| US8309329B2 (en) | 2012-11-13 |
| KR101599977B1 (ko) | 2016-03-04 |
| CN101960005A (zh) | 2011-01-26 |
| KR20100127784A (ko) | 2010-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |