BRPI0908087A2 - Composições e métodos para implante de tecido adipose e produtos de tecido adiposo - Google Patents

Composições e métodos para implante de tecido adipose e produtos de tecido adiposo

Info

Publication number
BRPI0908087A2
BRPI0908087A2 BRPI0908087-2A BRPI0908087A BRPI0908087A2 BR PI0908087 A2 BRPI0908087 A2 BR PI0908087A2 BR PI0908087 A BRPI0908087 A BR PI0908087A BR PI0908087 A2 BRPI0908087 A2 BR PI0908087A2
Authority
BR
Brazil
Prior art keywords
adipose tissue
compositions
methods
implantation
products
Prior art date
Application number
BRPI0908087-2A
Other languages
English (en)
Inventor
Gedge Rossen
Jennifer H Elisseeff
Zayna Nahas
Zhaoyang Ye
Alexander Hillel
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of BRPI0908087A2 publication Critical patent/BRPI0908087A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/80—Hyaluronan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
BRPI0908087-2A 2008-02-11 2009-02-11 Composições e métodos para implante de tecido adipose e produtos de tecido adiposo BRPI0908087A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6532208P 2008-02-11 2008-02-11
PCT/US2009/000887 WO2009102452A2 (en) 2008-02-11 2009-02-11 Compositions and methods for implantation of adipose tissue and adipose tissue products

Publications (1)

Publication Number Publication Date
BRPI0908087A2 true BRPI0908087A2 (pt) 2015-08-25

Family

ID=40957429

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908087-2A BRPI0908087A2 (pt) 2008-02-11 2009-02-11 Composições e métodos para implante de tecido adipose e produtos de tecido adiposo

Country Status (6)

Country Link
US (1) US9441200B2 (pt)
EP (1) EP2252686B1 (pt)
AU (1) AU2009215175B2 (pt)
BR (1) BRPI0908087A2 (pt)
CA (1) CA2715288C (pt)
WO (1) WO2009102452A2 (pt)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
CA2735173C (en) 2008-09-02 2017-01-10 Tautona Group Lp Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
FI20085839A0 (fi) * 2008-09-08 2008-09-08 Timo Ylikomi Menetelmiä ja välineitä pehmytkudosteknologiaan
AU2009308152B2 (en) * 2008-10-21 2015-05-21 The General Hospital Corporation Cell transplantation
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
US20100249924A1 (en) * 2009-03-27 2010-09-30 Allergan, Inc. Bioerodible matrix for tissue involvement
US8420077B2 (en) 2009-04-20 2013-04-16 Allergan, Inc. Silk fibroin hydrogels and uses thereof
CA2770490C (en) 2009-08-11 2024-04-16 The Johns Hopkins University Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products
BR112012014603A2 (pt) * 2009-12-17 2019-09-24 Univ Kingston método para descelularização de tecido adiposo, tecido adipose descelularizado, tecido adiposo descelularizado incluindo laminina, biosuporte, revestimento, esfera micro-transportadora e partícula
WO2012002986A2 (en) * 2009-12-21 2012-01-05 The Regents Of The University Of California Decellularized and delipidized extracellular matrix and methods of use
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
EP4062950A1 (en) 2010-03-22 2022-09-28 Allergan, Inc. Syringe comprising dermal filler for soft tissue augmentation
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
JP6072684B2 (ja) 2010-08-06 2017-02-01 ザ ジェネラル ホスピタル コーポレーション ディー/ビー/エイ マサチューセッツ ジェネラル ホスピタル 細胞処置システムおよび細胞処置装置
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8926963B2 (en) 2010-08-19 2015-01-06 Allergan, Inc. Compositions and soft tissue replacement methods
US8894992B2 (en) 2010-08-19 2014-11-25 Allergan, Inc. Compositions and soft tissue replacement methods
EP2605762A1 (en) 2010-08-19 2013-06-26 Allergan, Inc. Compositions comprising adipose tissue and a pge2 analogue and their use in the treatment of a soft tissue condition
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8741281B2 (en) 2010-08-19 2014-06-03 Allergan, Inc. Compositions and soft tissue replacement methods
US8900571B2 (en) 2010-08-19 2014-12-02 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9109198B2 (en) * 2011-04-29 2015-08-18 General Electric Company Automated systems and methods for isolating regenerative cells from adipose tissue
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
RU2624239C2 (ru) 2011-06-03 2017-07-03 Аллерган, Инк. Составы кожного наполнителя, включая антиоксиданты
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
WO2013106715A1 (en) * 2012-01-13 2013-07-18 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
WO2014150784A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
KR20160027127A (ko) * 2013-07-01 2016-03-09 아미트 프라카시 고빌 연조직 임플란트
WO2015017500A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
RU2715234C2 (ru) 2015-02-13 2020-02-26 Аллерган Эндюстри, Сас Имплантаты для моделирования, увеличения или коррекции частей лица, например подбородка
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
US11918658B2 (en) * 2017-04-12 2024-03-05 Massachusetts Institute Of Technology Hydrogels and related compositions and methods
WO2018231882A1 (en) * 2017-06-12 2018-12-20 Biotime, Inc. Implants, methods for making implants and methods of treating lipoatrophy defects therewith
KR102955766B1 (ko) 2018-05-03 2026-04-22 콜플랜트 리미티드 진피 충전제 및 이의 적용
CN109675108B (zh) * 2019-02-18 2021-06-04 上海交通大学医学院附属第九人民医院 利用脂肪组织和支架材料直接再生肥大软骨组织的方法
CN109675109B (zh) * 2019-02-18 2021-08-27 上海交通大学医学院附属第九人民医院 利用脂肪组织直接制备脱细胞肥大软骨基质的方法
US20230044236A1 (en) * 2019-12-17 2023-02-09 L&C Bio Co., Ltd. Medical Composition Comprising Adipose Tissue-Derived Extracellular Matrix And Method For Preparing Same
CN113144288A (zh) * 2021-04-26 2021-07-23 磐升瑞祥(山东)生物工程有限公司 一种复合多组分的胶原蛋白微乳填充剂及其制备方法
CN114908044A (zh) * 2022-05-13 2022-08-16 北京大学第三医院(北京大学第三临床医学院) 一种富含外泌体的微颗粒脂肪片段提纯方法及其乳化器

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69329594T2 (de) 1992-02-28 2001-05-31 Board Of Regents, The University Of Texas System Photopolymerinierbare, biologisch abbaubare hydrogele als gewebekontaktmaterialien und trägerstoffe für kontrollierte freisetzung
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US6224893B1 (en) 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
US20030082152A1 (en) * 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
RU2306335C2 (ru) 1999-03-10 2007-09-20 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Стволовые клетки и решетки, полученные из жировой ткани
US7004977B2 (en) * 1999-11-24 2006-02-28 A Enterprises, Inc. Soft tissue substitute and method of soft tissue reformation
US7625581B2 (en) 2003-12-19 2009-12-01 Ethicon, Inc. Tissue scaffolds for use in muscoloskeletal repairs
US20060134781A1 (en) 2004-12-07 2006-06-22 Bacterin International, Inc. Three-dimensional cell culture system
US7550152B2 (en) * 2005-01-19 2009-06-23 National University Of Ireland, Galway Tissue graft scaffold made from cholecyst-derived extracellular matrix
KR20070095494A (ko) * 2005-09-28 2007-10-01 세원셀론텍(주) 지방 조직 수복용 반고형성 젤 조성물의 제조방법

Also Published As

Publication number Publication date
AU2009215175A1 (en) 2009-08-20
WO2009102452A3 (en) 2009-10-29
US20110183001A1 (en) 2011-07-28
AU2009215175B2 (en) 2014-07-17
CA2715288A1 (en) 2009-08-20
CA2715288C (en) 2018-06-05
WO2009102452A2 (en) 2009-08-20
EP2252686A4 (en) 2013-01-09
EP2252686A2 (en) 2010-11-24
EP2252686B1 (en) 2017-10-11
US9441200B2 (en) 2016-09-13

Similar Documents

Publication Publication Date Title
BR112012003092A2 (pt) composições e métodos para implantação de tecido adiposo processado e produtos de tecido adiposo processados.
BRPI0807918A2 (pt) composições e método para preservação de tecido
BRPI0921959A2 (pt) métodos e composições para remoção de tatuagem
BRPI1015336A2 (pt) composições para tratamento de tecidos que compreendem polímeros de organossiloxano
BRPI1009920A2 (pt) composições bacterianas para profilaxina e tratamento de doença degenerativa.
PT2367561E (pt) Composições e métodos para o tratamento da doença celíaca
BR112012004979A2 (pt) composições para o tratamento de semente e métodos
BRPI0813725A2 (pt) Métodos e composições para tratamento de doenças
BRPI0909780A2 (pt) Composições e métodos para liberação de fármaco
BR112012031446A2 (pt) componentes e métodos para implantes
BRPI1012525A2 (pt) composições de nanopatículas isentas de príons e métodos para sua fabricação
BRPI1013829A2 (pt) composições e métodos para fermentação de biomassa
BR112013015452A2 (pt) composições e métodos para modular fxr
BR112012006808A2 (pt) "composições sanitizadoras e método para sanitização de superfície"
BRPI1007600A2 (pt) composições e métodos para tratamento de doenças cardiovasculares
EP2341852A4 (en) ORTHOPEDIC IMPLANT
BR112012000882A2 (pt) Preparação cosmética capilar e método para aplicação.
BR112012001666A2 (pt) composições de proteína rsv f e métodos para fazer as mesmas
FR2942627B1 (fr) Composition de graisse
BRPI0916670A2 (pt) estações ponderadas de isca para roedor e métodos relacionados
BRPI0920268A2 (pt) Método e aparelho para aumentar a fração de tecido adiposo vascular
PT2340042E (pt) Métodos e composições para o tratamento de cancro
BRPI0914300A2 (pt) composições e métodos para imunogenicidade intensificada de somatostatina
BRPI1006229A2 (pt) composição incluindo uma quantidade suficiente de curcumina
PT2512502T (pt) Métodos e composições para supressão de tumores

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL