BRPI0908181A2 - Solução de cardioplegia para cirurgia cardíaca - Google Patents

Solução de cardioplegia para cirurgia cardíaca

Info

Publication number
BRPI0908181A2
BRPI0908181A2 BRPI0908181-0A BRPI0908181A BRPI0908181A2 BR PI0908181 A2 BRPI0908181 A2 BR PI0908181A2 BR PI0908181 A BRPI0908181 A BR PI0908181A BR PI0908181 A2 BRPI0908181 A2 BR PI0908181A2
Authority
BR
Brazil
Prior art keywords
cardiac surgery
cardioplegia solution
cardioplegia
solution
cardiac
Prior art date
Application number
BRPI0908181-0A
Other languages
English (en)
Inventor
Hemant Thatte
Original Assignee
Harvard College
Us Dept Of Veterans Affairrs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Us Dept Of Veterans Affairrs filed Critical Harvard College
Publication of BRPI0908181A2 publication Critical patent/BRPI0908181A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BRPI0908181-0A 2008-02-15 2009-02-10 Solução de cardioplegia para cirurgia cardíaca BRPI0908181A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6595208P 2008-02-15 2008-02-15
PCT/US2009/000834 WO2009105165A2 (en) 2008-02-15 2009-02-10 Cardioplegia solution for cardiac surgery

Publications (1)

Publication Number Publication Date
BRPI0908181A2 true BRPI0908181A2 (pt) 2015-08-18

Family

ID=40986090

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908181-0A BRPI0908181A2 (pt) 2008-02-15 2009-02-10 Solução de cardioplegia para cirurgia cardíaca

Country Status (9)

Country Link
US (1) US20110059177A1 (pt)
EP (1) EP2252292A4 (pt)
JP (1) JP2011512351A (pt)
CN (1) CN102088977A (pt)
AU (1) AU2009215884A1 (pt)
BR (1) BRPI0908181A2 (pt)
CA (1) CA2715638A1 (pt)
IL (1) IL207595A0 (pt)
WO (1) WO2009105165A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0903299D0 (en) * 2009-02-26 2009-04-08 Guys And St Thomas Nhs Foundat Composition and methods
MX347919B (es) 2010-05-12 2017-05-17 Rempex Pharmaceuticals Inc * Composiciones de tetraciclina.
EP2611291B1 (en) * 2010-09-01 2020-03-25 Perfusion Fluid Technologies, Inc. Perfusion composition
US9770554B2 (en) * 2011-09-13 2017-09-26 Quest Medical, Inc. Cardioplegia apparatus and method
CA3153463A1 (en) 2012-10-29 2014-05-08 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
CA2923441C (en) * 2013-11-22 2023-03-28 Somahlution, Llc Solutions for increasing the stability and shelf life of an organ and tissue preservation solution
JP6292640B2 (ja) * 2014-05-30 2018-03-14 Sbiファーマ株式会社 臓器保存液
CN115813947A (zh) * 2014-07-11 2023-03-21 有氧运动系统制药有限责任公司 通用心脏麻痹液(多种变型)
JP6843599B2 (ja) * 2016-11-25 2021-03-17 テルモ株式会社 生細胞または生細胞を含む組成物の保存液
CN109769797B (zh) * 2017-11-13 2024-09-10 合肥华琪生物工程有限公司 一种器官保存液
IL256325A (en) * 2017-12-14 2018-01-31 Omrix Biopharmaceuticals Ltd Antibacterial preparations containing minocycline and breakdown products of oxidized cellulose
IT201800003896A1 (it) * 2018-03-27 2019-09-27 Alfasigma Spa Composizione acquosa stabile di fosfocreatina.
WO2020122928A1 (en) * 2018-12-14 2020-06-18 National Taiwan University A stable cardioplegic solution for cardiac surgery
US12472299B2 (en) * 2019-04-04 2025-11-18 Fuso Pharmaceutical Industries, Ltd. Reservoir assembly for providing cardioplegic solution containing bicarbonate ion, and method for manufacturing the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130230A (en) * 1988-05-02 1992-07-14 Cryomedical Sciences, Inc. Blood substitute
US5075210A (en) * 1989-12-21 1991-12-24 The Regents Of The University Of California Preservation of the heart for transplantation
US5407793A (en) * 1991-10-18 1995-04-18 University Of Pittsburgh Of The Commonwealth System Of Higher Education An aqueous heart preservation and cardioplegia solution
US6680305B1 (en) * 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
US5945272A (en) * 1993-06-04 1999-08-31 Biotime, Incorporated Plasma expanders and blood substitutes
US5554497A (en) * 1994-12-12 1996-09-10 Charlotte-Mecklenburg Hospital Authority Cardioplegic solution for arresting an organ
US6569615B1 (en) * 2000-04-10 2003-05-27 The United States Of America As Represented By The Department Of Veteran's Affairs Composition and methods for tissue preservation
SE0002832D0 (sv) * 2000-08-07 2000-08-07 Jostra Ab Cardioplegic solution
US6310094B1 (en) * 2001-01-12 2001-10-30 Baxter International Inc. Ready-to-use esmolol solution
US20030124503A1 (en) * 2001-12-28 2003-07-03 Olivencia-Yurvati Albert H. Pyruvate cardioplegia solutions for administration to the heart during cardiopulmonary surgery and methods of use thereof
AUPS312602A0 (en) * 2002-06-21 2002-07-18 James Cook University Organ arrest, protection, preservation and recovery
US7109169B2 (en) * 2002-06-28 2006-09-19 Hobai Ion A Method for treating heart failure by inhibiting the sarcolemmal sodium/calcium exchange
US7575856B2 (en) * 2005-10-28 2009-08-18 The United States Of America As Represented By The Department Of Veterans Affairs Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant
US7763607B2 (en) * 2006-04-27 2010-07-27 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators

Also Published As

Publication number Publication date
EP2252292A2 (en) 2010-11-24
US20110059177A1 (en) 2011-03-10
WO2009105165A2 (en) 2009-08-27
CN102088977A (zh) 2011-06-08
JP2011512351A (ja) 2011-04-21
WO2009105165A3 (en) 2009-11-19
AU2009215884A1 (en) 2009-08-27
CA2715638A1 (en) 2009-08-27
IL207595A0 (en) 2010-12-30
EP2252292A4 (en) 2011-03-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.